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Brandon M Roberts

Brandon M Roberts
USARIEM · Military Performance

PhD

About

27
Publications
21,783
Reads
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750
Citations
Additional affiliations
September 2016 - September 2019
University of Alabama at Birmingham
Position
  • PostDoc Position
April 2012 - August 2016
University of Florida
Position
  • Research Assistant
August 2010 - August 2012
University of Florida
Position
  • Research Assistant

Publications

Publications (27)
Article
Age-related muscle loss (sarcopenia) is a major clinical problem affecting both men and women - accompanied by muscle weakness, dysfunction, disability, and impaired quality of life. Current definitions of sarcopenia do not fully encompass the age-related changes in skeletal muscle. We therefore examined the influence of aging and sex on elements o...
Article
Full-text available
Skeletal muscle is highly adaptable and has consistently been shown to morphologically respond to exercise training. Skeletal muscle growth during periods of resistance training has traditionally been referred to as skeletal muscle hypertrophy, and this manifests as increases in muscle mass, muscle thickness, muscle area, muscle volume, and muscle...
Article
Full-text available
Roberts, BM, Nuckols, G, and Krieger, JW. Sex differences in resistance training: A systematic review and meta-analysis. J Strength Cond Res XX(X): 000-000, 2020-The purpose of this study was to determine whether there are different responses to resistance training for strength or hypertrophy in young to middle-aged males and females using the same...
Article
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Introduction The cadets in the U.S. Army Reserve Officers’ Training Corps (ROTC) consist of students from varied backgrounds. As part of collegiate ROTC programs, cadets must pass fitness tests and adhere to body composition standards in addition to completing their education. The previous fitness test of record was the Army Physical Fitness Test (...
Article
Full-text available
Martínez-Gómez, MG and Roberts, BM. Metabolic adaptations to weight loss: A brief review. J Strength Cond Res XX(X): 000-000, 2021-As the scientific literature has continuously shown, body mass loss attempts do not always follow a linear fashion nor always go as expected even when the intervention is calculated with precise tools. One of the main r...
Article
Full-text available
Nutritional ketosis as a therapeutic tool has extended to the treatment of metabolic diseases including - obesity, type 2 diabetes and nonalcoholic fatty liver disease. The purpose of this study was to determine whether dietary administration of the ketone ester (KE), R,S-1,3-butanediol diacetoacetate (BD-AcAc 2 ), attenuates markers of hepatic ste...
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Full-text available
Cancer cachexia is a syndrome characterized by profound cardiac and diaphragm muscle wasting, which increase the risk of morbidity in cancer patients due to failure of the cardiorespiratory system. In this regard, muscle relies greatly on mitochondria to meet energy requirements for contraction and mitochondrial dysfunction can result in muscle wea...
Article
Objective The aim of this study was to examine the effects of a ketone ester (KE)‐supplemented diet on energy expenditure (EE) and adiposity in mice housed at 23 °C versus thermoneutrality (30 °C), in which sympathetic nervous system activity is diminished. Methods Thirty‐two 10‐week‐old male C57BL/6J mice were assigned to 1 of 4 groups (n = 8 per...
Article
In the past decades, the ketogenic diet has received scientific interest as a diet which may be beneficial for athletes. We summarize the ketogenic literature and give competitive bodybuilders and physique athletes advice on whether the diet and ketone supplements are suitable for off-season and in-season use. The diet is effective for fat loss a...
Article
Skeletal muscle wasting is a devastating consequence of cancer that contributes to increased complications and poor survival, but is not well understood at the molecular level. Herein, we investigated the role of Myocilin (Myoc), a skeletal muscle hypertrophy-promoting protein that we showed is downregulated in multiple mouse models of cancer cache...
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Full-text available
The popularity of physique sports is increasing, yet there are currently few comprehensive nutritional guidelines for these athletes. Physique sport now encompasses more than just a short phase before competition and offseason guidelines have recently been published. Therefore, the goal of this review is to provide an extensive guide for male and f...
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Parkinson's disease (PD) is a common neurodegenerative disorder impacting cognition, movement, and quality of life in >10 million individuals worldwide. We recently characterized and quantified a skeletal muscle pathology in PD represented by exaggerated type I myofiber grouping presumed to result from denervation-reinnervation processes. Our previ...
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Full-text available
Holland, BM, Roberts, BM, Krieger, JW, and Schoenfeld, BJ. Does HMB enhance body composition in athletes? A systematic review and meta-analysis. J Strength Cond Res XX(X): 000-000, 2019-The purpose of this article was to systematically review and meta-analyze the current literature to determine the effects of HMB on body composition in athletes. St...
Article
Older adults undergoing age-related decrements in muscle health can benefit substantially from resistance exercise training, a potent stimulus for whole muscle and myofiber hypertrophy, neuromuscular performance gains, and improved functional mobility. With the use of advancing technologies, research continues to elucidate the mechanisms of and het...
Data
Supplemental Table 1: Respiratory values during plethysmography studies. Values are expressed as mean ± SEM. Supplemental Table 2: Physiological variables during neurophysiology studies. No significant difference was observed within expiratory carbon dioxide, oxygen (O2) saturation at baseline, or oxygen (O2) saturation during hypoxic challenge. S...
Preprint
The primary means for disseminating sport and exercise science research is currently through journal articles. However, not all studies, especially those with null findings, make it to formal publication. This publication bias towards positive findings may contribute to questionable research practices. Preregistration is a solution to prevent the pub...
Article
Full-text available
Purpose: To examine data reporting characteristics in sports nutrition. Methods: We examined 236 papers from ten journals published in 2016. The primary outcome was statistical variance associated with treatment (SD (correct) vs. SEM or CI). Secondary outcomes included the reporting of: (a) effect sizes (Y/N); (b) outcome prioritization (Y/N; prima...
Article
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Background: Cancer cachexia is an insidious process characterized by muscle atrophy with associated motor deficits, including diaphragm weakness and respiratory insufficiency. Although neuropathology contributes to muscle wasting and motor deficits in many clinical disorders, neural involvement in cachexia-linked respiratory insufficiency has not...
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Purpose: The myriad consequences of age-related muscle atrophy include reduced muscular strength, power, and mobility; increased risk of falls, disability, and metabolic disease; and compromised immune function. At its root, aging muscle atrophy results from a loss of myofibers and atrophy of the remaining type II myofibers. The purpose of this tr...
Article
Skeletal muscle hypertrophy is a widely sought exercise adaptation to counteract the muscle atrophy of aging and disease, or to improve athletic performance. While this desired muscle enlargement is a well-known adaptation to resistance exercise training (RT), the mechanistic underpinnings are not fully understood. The purpose of this review is thu...
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Respiratory dysfunction is prevalent in critically ill patients, and can lead to adverse clinical outcomes including respiratory failure and increased mortality. Respiratory muscles, which normally sustain respiration through inspiratory muscle contractions, become weakened during critical illness, and recent studies suggest that respiratory muscle...
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Full-text available
Evidence from cachectic cancer patients and animal models of cancer cachexia supports the involvement of Forkhead box O (FoxO) transcription factors in driving cancer-induced skeletal muscle wasting. However, the genome-wide gene networks and associated biological processes regulated by FoxO during cancer cachexia are unknown. We hypothesize that F...
Article
Full-text available
The Forkhead boxO (FoxO) transcription factors are activated and necessary for the muscle atrophy during several pathophysiological conditions, including muscle disuse and cancer cachexia. Yet, the mechanisms which lead to FoxO activation are not well defined. Recent data from our lab and others indicate that the activity of FoxO is repressed under...
Article
Full-text available
Cancer cachexia is characterized by a continuous loss of locomotor skeletal muscle mass, which causes profound muscle weakness. If this atrophy and weakness also occurs in diaphragm muscle, it could lead to respiratory failure, which is a major cause of death in patients with cancer. Thus, the purpose of the current study was to determine whether c...

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Projects

Projects (4)
Project
To determine how various NSAIDs influence bone metabolism and skeletal muscle.
Project
To summarize our understanding of how ‘metabolic adaptations’ can affect weight loss and weight regain over time and what are the possible nutritional solutions proposed to mitigate these phenomena