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Introduction
Additional affiliations
May 2013 - present
September 2011 - October 2012
Uniclon Biotecnologia Ltda
Position
- Researcher
March 2011 - May 2013
Publications
Publications (63)
About 2% of the oil consumed worldwide is related to the production of automotive and industrial lubricating oils. The pollution derived from these oils in aquatic and terrestrial environments is responsible for several ecological and social problems due to their toxic, mutagenic, and carcinogenic properties. Thus, studies related to bioremediation...
Objective: The aim of this experimental assay was to produce citric acid via submerged fermentation, using hemicellulose hydrolysate from coffee husks as main substrate. Theoretical framework: Obtaining citric acid through fermentation processes, especially submerged fermentation, has become viable due to the use of low-cost materials, such as indu...
This study evaluated the stability of the Poly-(sorbitol-co-citrate adipate) with potential applica-tion in the biomedical area. Thus, the physical, chemical and microbiological stability of this was investigated. First, the chemical stability in alkaline phosphate buffer (pH 7.4) was evaluated for 5 days. In aqueous solution, the copolymer acidifi...
Vinasse is one of the most polluting effluents in the sugar–alcohol industry due to its physicochemical properties. The common methods of treatment are not able to supply all the volume generated, and therefore, efforts are needed to obtain new technologies that are efficient in the management of this waste. So, this work aims to evaluate sugarcane...
Vinasse is one of the most polluting effluents in the sugar-alcohol industry due to its physicochemical properties. It poses a threat to soil fertility and can contaminate groundwater if not appropriately handled. Therefore, it is important to evaluate more sustainable and comprehensive vinasse treatment strategies to safeguard environmental integr...
This study presents an exergetic analysis of xylitol fermentative production from hemicellulose hydrolysate, aiming to optimize operational conditions in a fluidized bed bioreactor. The aerobic fermentation conditions evaluated in this study (gas flow rate - x1, hydrolysate concentration factor - x2, and recirculation flow rate - x3) were optimized...
The present work presents the results obtained in the production of vanillin-doped alginate biopolymeric film using green chemistry methodology. Alginate dressings are already a therapeutic reality, but they act only by maintaining the appropriate environment for healing. In order to improve their properties, the incorporation of vanillin was propo...
Vinasse is one of the most polluting effluents in the sugar-alcohol industry due to its physicochemical properties. It poses a threat to soil fertility and can contaminate groundwater if not appropriately handled. Therefore, it is important to evaluate more sustainable and comprehensive vinasse treatment strategies to safeguard environmental integr...
The present work presents the results of the production of vanillin-doped alginate biofilm. Alginate dressings are already a therapeutic reality, but they act only by maintaining the appropriate environment for healing. With the intention of improving their properties, the incorporation of vanillin was proposed due to its antioxidant and antimicrob...
This work describes the synthesis and physicochemical and microstructural characterization of poly(sorbitol adipate co-citrate) with the aim of obtaining a sustainable biopolymer derived from renewable and non-toxic sources intended for applications such as biomaterial. Polymerizations at three different ratios of sorbitol and adipic and citric aci...
Lipases are hydrolases used in various sectors such as the food, pharmaceutical and chemical synthesis industries. In this study, epiphytic microorganisms were isolated from the Serra of Ouro Branco State Park (Minas Gerais, Brazil) and were subsequently evaluated for their ability to produce extracellular lipases. Among the 46 isolated strains, 25...
Lignin has aroused great interest in the scientific and economic areas because of its aromatic and complex nature. It can be used as a raw material for obtaining aromatic aldehydes but the great potential of lignin is not satisfactorily utilized. The interest is justified by the fact that, when its structure is spun off through pre-treatment proces...
In this study, hybrid models for specific chemical exergy prediction were proposed for pure organic compounds. The models were designed from the relation between the compounds standard molar chemical exergy and the reaction Gibbs energy and employing a dataset consisting in 178 pure organic compounds. The model performance was compared to available...
Different methods of chemical exergy estimation for several organic compounds have been proposed in literature, mainly for those related to the petrochemical and energy industry. However, there is a lack of specific models for the estimation of different biomolecules chemical exergy. The present work aimed to evaluate the performance of two specifi...
Biopolymers are sustainable materials derived from renewable sources that have relevant and industrially attractive properties such as biodegradability, biocompatibility and antimicrobial effect. Thus, these were the target of several experimental studies, widely published in the literature and used in our daily lives. This paper presents a prelimi...
The excessive use of phthalates (PHEs) plasticizers has promoted a serious environmental problem. This study evaluated the biodegradation of PHEs from polyvinyl chloride (PVC) film, aiming to mitigate damage to the environment. Therefore, 23 microorganisms were prospected and isolated from the Serra do Ouro Branco State Park (Minas Gerais, Brazil),...
Verifica-se carência na literatura de modelos específicos de estimação de propriedades para moléculas de interesse biotecnológico, levando à aplicação de metodologias alternativas para o cálculo. Principalmente na literatura nacional, observa-se um volume reduzido de trabalhos destinados a avaliar métodos de estimação de propriedades para as molécu...
This study updates the introduction of non-native fishes Nannostomus beckfordi , Aphyocharax anisitsi , Knodus moenkhausii , Moenkhausia costae , Ancistrus multispinis and Astronotus ocellatus in the largest ornamental aquaculture center located in Paraíba do Sul River basin, state of Minas Gerais, Brazil. There is evidence that all species are est...
Residual glycerin, a co-product obtained in the biodiesel production by transesterification reaction, has been generated
in great quantities in the last decade due to the increase in the demand of this biofuel. Therefore, researches related
to the production of high added value and environmental friendly materials using residual glycerin are fundam...
A glicerina loira, um coproduto obtido na produção do biodiesel pela reação de transesterificação, tem sido gerado na última década, em grandes quantidades cada vez maiores, devido ao aumento na produção desse biocombustível. Dessa forma, tornam-se importantes pesquisas relacionadas ao desenvolvimento de materiais e produtos que agreguem valor e de...
O Brasil é um dos maiores produtores mundiais de etanol proveniente de cana-de-açúcar. No processo de produção do biocombustível etanol vários resíduos são gerados, dentre eles destaca-se a vinhaça como o mais preocupante, devido as suas características físico-químicas e grande volume gerado. Este efluente é caracterizado altos teores de matéria or...
Due to economic, geopolitical, and environmental issues, the world’s attention turns to alternative energy sources, especially for second-generation ethanol. In addition to economic considerations, other factors such as energy security, greenhouse gas emissions, and global climate change are boosting scientific researches concerning alternative bio...
Since the first successful attempt at sequencing the Corynebacterium pseudotuberculosis genome, large amounts of genomic, transcriptomic and proteomic data have been generated. C. pseudotuberculosis is an interesting bacterium due to its great zoonotic potential and because it causes considerable economic losses worldwide. Furthermore, different st...
The present paper studies the biotechnological production of xylitol using sugarcane bagasse hydrolysate in a repeated batch fermentation system with immobilized cells of Candida guilliermondii FTI20037. Immobilized cell system is considered as an attractive alternative to reuse the well-grown and adapted yeast cells in a new fresh fermentation med...
Ten yeast strains were evaluated concerning their capabilities to assimilate biodiesel-derived glycerol in batch cultivation. The influence of glycerol concentration, temperature, pH and yeast extract concentration on biomass production was studied for the yeast selected. Further, the effect of agitation on glycerol utilization by the yeast Hansenu...
Processos biotecnológicos têm sido desenvolvidos e aplicados com sucesso para a obtenção de novos produtos. Entre estes, um em desenvolvimento é o uso de microorganismos que fermentam a xilose da fração hemicelulósica de resíduos agroindustriais à xilitol, um alimento funcional com importantes aplicações industriais. Dentre os resíduos agroindustri...
This work aims to contribute to the development of a viable technology for the production of xylitol from sugarcane bagasse hemicellulose hydrolysate, using a fluidized bed bioreactor with yeast cells of Candida guilliermondii FTI 20037. To evaluate the technical viability of this biotechnological process, simple batch fermentations were realized a...
Dilute-acid hydrolysis pretreatment of sugarcane bagasse resulted in release of 48% (18.4g/L) of the xylan in the hemicellulose
fraction into the hydrolysate as monomeric xylose. In order to enhance the recuperation of this monomer, a post-hydrolysis
stage consisted of thermal treatment was carried out. This treatment resulted in an increase in xyl...
BACKGROUND: Xylitol is a sugar alcohol (polyalcohol) with many interesting properties for pharmaceutical and food products. It is currently produced by a chemical process, which has some disadvantages such as high energy requirement. Therefore microbiological production of xylitol has been studied as an alternative, but its viability is dependent o...
In this paper, two new strians, Issatchenkia occidentalis (Lj-3, CCTCC M 2006097) and Issatchenkia orienalis (S-7, CCTCC M 2006098), isolated from different environments on solid media, were used in the detoxification process of the hemicellulosic hydrolysate of sugarcane bagasse. High-pressure liquid chromatography elution curve of UV-absorption c...
The present paper studies the influence of different nutrients for the production of two cellulolytic enzymes: endo beta-1.4 glucanase and exo beta- 1.4 glucanase by anaerobic fungi taken from cow rumen, that were fed a diet of corn silage and Brachiaria decumbens grass hay. During the enzymatic degradation assays, it was observed that the addition...
The bioethanol industry expects a huge expansion and new technologies are being implemented with the aim of optimizing the fermentation process. The behavior of cells of Saccharomyces cerevisiae immobilized in PVA-LentiKats, during the production of bioethanol in two reactor systems, was studied. The entrapped cell in LentiKats lenses showed a diff...
Given the increasing demand for reducing environmental pollution by Using clean energy, there is an urgent need to investigate new and more efficient alternatives for renewable resources use and clean energy production. Although biofuels such as, biodiesel represents a secure, renewable and environmentally safe alternative to fossil fuels. Its prod...
The use of the biotechnological way to xylitol production can represent minors production costs, whereas, in this case, it can be worked under reduced conditions of pressure and temperature and does not have necessity of purification of the hydrolysate. Among the searched alternatives, the Submerged Fermentation method is more extensively studied,...
Lignocellulose is the major structural component of woody plants such as sugar cane bagasse which represents an import source of renewable organic matter. Lignocellulose consists of lignin, hemicellulose and cellulose. The chemical properties of the components of lignocellulosics make them a substrate of enormous biotechnological value. The huge am...
This study provides a preliminary contribution to the development of a bioprocess for the continuous production of xylitol from hemicellulosic hydrolyzate utilizing Candida guilliermondii cells immobilized onto natural sugarcane bagasse fibers. To this purpose, cells of this yeast were submitted to batch tests of “in situ” adsorption onto crushed a...
The fluidized bed reactor has successfully been used to perform biotechnological processes addressed to the production of high added value. The present work evaluates hydrodynamic parameters of a bench-scale fluidized bed reactor with cells of the yeast Candida guilliermondii immobilized either in calcium alginate beads or in polyvinyl alcohol (PVA...
This work deals with the evaluation of the hydrodynamic characteristics and fermentation parameters of a bench-scale three-phase fluidized bed reactor (FBR) with cells of the yeast Candida guilliermondii immobilized calcium alginate beads for xylitol production. The effects of the following hydrodynamic variables on cell immobilization were evaluat...
El uso de biomasa renovable como sustrato en procesos biotecnológicos es una alternativa sostenible y adecuada que permite la producción de nuevos alimentos, productos químicos y farmacéuticos evitando el daño al medio ambiente. Brasil es un país conocido por su gran cantidad de recursos renovables, tales como el bagazo de caña de azúcar generado a...
As citoquinas são um grupo de glicoproteínas que atuam na resposta imune, unindo-se aos receptores nas membranas celulares para transmitir as informações. Possuem inúmeras fun-ções biológicas e podem ser produzidas por praticamente todos os tipos de células, dentre elas, as mais importantes são os linfócitos, monócitos e macrófagos. Recentemente, t...
As citoquinas são mediadores extremamente importantes no sistema imunológico humano, estando associadas a diversos processos inflamatórios, bem como ao tratamento de diver-sas doenças. Em muitos estudos, um exame completo para caracterizar inflamações requer a medida exata dos níveis de citoquinas no sangue. Dessa forma, este trabalho apresenta uma...
Resumo As citoquinas são mediadores extremamente importantes no sistema imunológico humano, estando associadas a diversos processos inflamatórios, bem como ao tratamento de diver-sas doenças. Em muitos estudos, um exame completo para caracterizar inflamações requer a medida exata dos níveis de citoquinas no sangue. Dessa forma, este trabalho aprese...
The claim for reducing environment pollution stimulates the world market of clean fuels. Biofuels
as biodiesel, represents a renewable and environmentally safety alternative to fossil fuel.
Nonetheless, its production is increasing considerably, and as a consequence, the amount of
raw glycerol (byproduct) generated is growing exponentially. With th...
The production cost of ethanol depends on the cost of the raw material. The new developed technologies of production allow the production of ethanol starting from lignocellulosic biomass, constituted by the fibrous part of the plants and in special of the remainders or Agro-industrial by-products. For example harvest and processing of maize, bagass...
Cells of Candida guilliermondii entrapped in Ca-alginate beads were used for xylitol production, from concentrated hemicellulose hydrolyzate of sugarcane bagasse, in a fluidized bed bioreactor (FBR). The maximum xylitol concentration 28.9 g xylitol/L was obtained at a high aeration rate of 600 mL/min after 70 h of fermentation, indicating that the...
In an attempt at improving bioethanol production, a bench-scale comparison has been performed between the traditional one-step process of sugarcane bagasse hydrolysis with 70 % sulfuric acid, and a modified operation including a second step with more dilute acid, at higher temperature. The influence of the reaction time, the percentage of solids in...
Lignocellulosic residues, like sugar cane bagasse generated by the sugar-alcohol industries, is the most abundant biomass in Brazil. It is necessary to find new technologies to use this renewable biomass in different processes to produce economically valuable products. Xylitol is an anticariogenic poliol with negative dissolution heat and presentin...
The semisolid fermentation (FSS) was consolidated as an alternative and attractive technology for the substitution of the submerged fermentation in various technological applications. This applications is presenting a growth increased in western countries, due its Technical-economical viability. This review article has as objective demonstrate the...
Nos últimos 25 anos o conhecimento da imunologia passou por importantes mudanças, sendo atualmente a imunologia considerada como uma ciência per si e isto ocasionou relevantes avanços nos modelos terapêuticos de inúmeras patologias através do estudo e analise das citoquinas. As citoquinas são fatores solúveis elaborados principalmente pelas células...
This work deals with acid hydrolysis of bagasse in lust one step and in a modified step using concentrated sulphuric acid. The study analysed the influence of three independent variables on the single-step process (reaction time, solid percentage of bagasse and temperature). The highest conversion obtained in single-step hydrolysis was
87.65% ferme...
This work deals with acid hydrolysis of bagasse in just one step and in a modified step using concentrated sulphuric acid. The study analysed the influence of three independent variables on the single-step process (reaction time, solid percentage of bagasse and temperature). The highest conversion obtained in single-step hydrolysis was 87.65% ferme...