Boris Noskov

Boris Noskov
Saint Petersburg State University | SPBU · Department of Colloid Chemistry

Doctor of Sience

About

170
Publications
10,706
Reads
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3,684
Citations
Citations since 2017
52 Research Items
1635 Citations
2017201820192020202120222023050100150200250300
2017201820192020202120222023050100150200250300
2017201820192020202120222023050100150200250300
2017201820192020202120222023050100150200250300
Additional affiliations
June 2012 - present
Saint Petersburg State University
Position
  • Professor (Full)
March 2004 - May 2005
University of Florence
Position
  • invited professor
November 2000 - June 2012
Saint Petersburg State University
Position
  • Professor (Full)

Publications

Publications (170)
Article
Full-text available
The interactions of DNA with lysozyme in the surface layer were studied by performing infrared reflection–absorption spectroscopy (IRRAS), ellipsometry, surface tensiometry, surface dilational rheology, and atomic force microscopy (AFM). A concentrated DNA solution was injected into an aqueous subphase underneath a spread lysozyme layer. While the...
Article
The properties of adsorbed layers of protein fibrils differ significantly from the properties of fibril spread layers on an aqueous subphase. If the dependencies of the dynamic surface elasticity on surface pressure of Lysozyme (LYS) and β-lactoglobulin (BLG) aqueous dispersions proved to be close to the results for native protein solutions, LYS an...
Article
Full-text available
The spread layers of lysozyme (LYS) microgel particles were studied by surface dilational rheology, infrared reflection–absorption spectra, Brewster angle microscopy, atomic force microscopy, and scanning electron microscopy. It is shown that the properties of LYS microgel layers differ significantly from those of ß-lactoglobulin (BLG) microgel lay...
Article
Using infrared reflection–absorption spectroscopy, surface tensiometry and atomic force microscopy it is demonstrated that a network of fibrous aggregates of DNA–cationic polyelectrolyte complexes is formed at the water–air interface, the mechanism of the network generation depending on the initial surface pressure of the polyelectrolyte monolayer.
Article
The spread and adsorbed layers of β-lactoglobulin (BLG) microgel were investigated by the dilational surface rheology, atomic force microscopy and optical microscopy. It is shown that only careful purification of the BLG microgel dispersion gives a possibility to observe distinctions between the properties of spread layers of BLG nano- and micro pa...
Article
The dynamic and equilibrium surface tension (ST) data of proteins such as bovine serum albumin (BSA) are crucial in numerous theoretical and practical applications. However, reliable equilibrium ST of BSA is absent in the literature. This study illustrates a more precise and accurate approach for measuring equilibrium ST of aqueous BSA solutions. T...
Article
A new approach for evaluating the dilational modulus of an adsorbed protein film was proposed in this study; wherein, the air-water interface of Bovine serum albumin (BSA) aqueous solution was not subjected to a forced perturbation. The approach involved: (i) monitoring the relaxations of surface tension (ST), surface area (SA), and ambient/solutio...
Article
This work is directed to the elucidation of the peculiarities of fullerene C60 interactions with bovine serum albumin (BSA) in mixed layers at the water-air interface. To this aim, the dilational surface elasticity was measured as a function of surface pressure and surface age and optical methods together with the atomic force microscopy (AFM) were...
Article
Full-text available
The formation of ordered 2D nanostructures of double stranded DNA molecules at various interfaces attracts more and more focus in medical and engineering research, but the underlying intermolecular interactions still require elucidation. Recently, it has been revealed that mixtures of DNA with a series of hydrophobic cationic polyelectrolytes inclu...
Article
Full-text available
Physicochemical properties of lipid monolayer depend on its composition where a blend of lipids exhibit superior behaviour than the individual component. Surface pressure (π) – area (A) isotherms of mixed monolayer (PCmix) formed by dipalmitoylphosphatidylcholine (DPPC), palmitoleylphosphatidylcholine (POPC), soyphosphatidylcholine (SPC) and hydrog...
Article
Measurements of the dynamic surface elasticity and surface pressure of solutions of green fluorescent protein (GFP) indicate the formation of a dense protein monolayer with a relatively high surface elasticity of approximately 65 mN/m, and are typical for solutions of globular proteins. The mixed solutions of GFP and poly(N,N-diallyl-N-hexyl-N-meth...
Article
The pulmonary surfactant (PS) is a complex mixture of lipids and proteins dispersed in the aqueous lining layer of the alveolar surface. Such a layer plays a key role in maintaining the proper lung functionality. It acts as a barrier against inhaled particles and pathogens, including viruses, and may represent an important entry point for drugs del...
Article
The addition of denaturants strongly influences the surface properties of aqueous myoglobin solutions. The effect differs from the results for mixed solutions of the denaturants and other globular proteins, for example, bovine serum albumin (BSA), lysozyme and β-lactoglobulin (BLG), although the surface properties of the solutions of the pure prote...
Article
The application of dilational surface rheology and optical microscopy combined with the more conventional methods of surface tensiometry, ellipsometry and atomic force microscopy shows that the properties of mixed spread layers of fullerene C60 with poly(vinylpyrrolidone) (PVP) and poly(N-isopropylacrylamide) (PNIPAM) are determined by the polymer...
Article
The dynamic surface properties of solutions of pulmonary surfactant (PS) were investigated at various temperatures and in a broad range of surface tensions. The efficient dynamic surface elasticity was determined for the first time in case when the characteristic adsorption time is comparable with the period of surface area oscillations. The mechan...
Article
The adsorption kinetics of anionic surfactant Aerosol-OT (AOT) in 10 mM NaCl solution was investigated by measuring and simulating the dynamic and equilibrium surface tension (ST) data. The relaxation of ST for AOT molecules adsorbing onto a freshly created bubble surface was measured using a video-enhanced pendant bubble tensiometer at eighteen AO...
Article
Full-text available
An increase in temperature typically leads to a decrease in the interfacial tension of a water/oil interface. The addition of surfactants to the system can complicate the situation significantly, i.e., the interfacial tension can increase or decrease with an increasing temperature. For most concentrations of the two studied surfactants, the cationi...
Article
Polydopamine (PDA) films at the air - water interface can be easily obtained in slightly alkaline dopamine solutions using 02 dissolved in water as an oxidant but their insufficient stability limits their applications. In this work PDA films at the water surface were obtained by polymerization of dopamine hydrochloride (DA) by the enzyme laccase in...
Article
The article presents novel physicochemical data on C60(OH)24 aqueous solutions. Temperature and concentration dependencies of density (ρ) and speed of sound (u) and surface tension (γ) were obtained. Additionally, the study of human serum albumin (HSA) binding to C60(OH)24 fullerenol was conducted, and thermodynamic characteristics of C60(OH)24–HSA...
Article
The surface properties of fullerenol C60(OH)20 solutions differ significantly from the properties of solutions of more hydrophilic fullerenols. At concentrations below 1 g/l, dynamic surface elasticity proves to be very high (up to 300 mN/m), while surface tension decreases only slightly. The adsorption layer is very sensitive to mechanical perturb...
Article
The review discusses recent results on the adsorption of amyloid fibrils and protein microgels at liquid/fluid interfaces. The application of the shear and dilational surface rheology, atomic force microscopy and passive particle probe tracking allowed for elucidating characteristic features of the protein aggregate adsorption while some proposed h...
Article
Full-text available
In this communication, the single element version of the fractional Maxwell model (single-FMM or Scott–Blair model) is adopted to quantify the observed behavior of the linear interfacial dilational viscoelasticity. This mathematical tool is applied to the results obtained by capillary pressure experiments under low-gravity conditions aboard the Int...
Article
Several characteristics of β-lactoglobulin (BLG) layers adsorbed at the air/water interface exhibit a strong pH dependence, but our knowledge on the underlying structure-property relations is still fragmental. Here, we therefore extend our recent studies by neutron reflectometry (NR) and provide a comprehensive overview through direct measurements...
Article
It is discovered that complexes of DNA and hydrophobically modified polyelectrolytes form a rigid network of threadlike or fibrous aggregates at the liquid – gas interface whose morphology can dramatically affect the mechanical properties. While mixed solutions of DNA and poly(N,N-diallyl-N,N-dimethylammonium chloride) (PDADMAC) exhibit no notable...
Article
This work is focused on the study of the dynamic surface properties of spread monolayers of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), which is the main component of the pulmonary surfactant (PS), in the region of high surface pressures and at different temperatures. The increase of temperature from 25 to 35 °C led to a decrease of surface...
Article
In this paper, experimental data on different physicochemical properties of С60[C(COOH)2]3 aqueous solutions are presented. Concentration and temperature dependences on density (ρ), viscosity (η), refractive index (nD), speed of sound (u), surface tension (γ), as well as nanoparticle size dimensions (δi) of water solutions were obtained and charact...
Article
The surface properties of a polydopamine layer at the air-water interface were studied by dilatational surface rheology, ellipsometry and Brewster angle microscopy (BAM). A significant increase of the dynamic surface elasticity was discovered when the concentration changed from 0.75 g/l to 2 g/l with the maximum value of about 60 mN/m at a concentr...
Article
The surface properties of mixed aqueous dispersions of lysozyme and silica nanoparticles were studied using surface-sensitive techniques in order to gain insight into the mechanism of simultaneous adsorption of protein/nanoparticle complexes and free protein as well as the resulting layer morphologies. The properties were first monitored in situ du...
Article
In this work, dynamic surface properties of spread monolayers of DPPC and adsorbed layers of PS solutions were investigated in a broad range of surface pressure. Application of a modified Langmuir trough and a recently developed approach for the analysis of a non-linear response of the adsorption layer to large surface deformations gives a possibil...
Article
The dilational surface rheology was applied to study the properties of adsorbed layers of a fluorinated surfactant (heptadecafluoro-1-nonanol) with a surface phase transition at the water – air interface. At relatively low surface tensions (<~57 mN/m) the dynamic surface elasticity reached anomalously high values (~200 mN/m) and exhibited a local m...
Article
Application of the dilational surface rheology, surface tensiometry, ellipsometry, Brewster angle, transmission electron and atomic force microscopies allowed estimation of the structure of the adsorption layer of a fullerenol with a large number of hydroxyl groups, C60(OH)X (X = 30 ±2). The surface properties of fullerenol solutions proved to be s...
Article
The paper is devoted to the physico-chemical investigation of the C 70 -Thr aqueous solutions. In the framework of our study, we measured densities (ρ), viscosities (η), refraction indexes (n D ) and surface tension (γ) in a wide range of concentrations. Experimental data on size distribution and ζ-potentials of the C 70 -Thr associates in aqueous...
Article
Full-text available
Capillary pressure experiments are performed in microgravity conditions on board the International Space Station to quantify the dynamic interfacial behavior of mixed adsorption layers of TTAB and C13DMPO at the water/hexane interface. While the non-ionic surfactant C13DMPO is soluble in both bulk phases, water and hexane, the cationic surfactant T...
Article
Full-text available
Interaction between negatively charged liposomes and cationic polyamidoamine dendrimers of different generations was investigated through size, zeta potential, turbidity, electron microscopy, atomic force microscopy, fluorescence spectroscopy, and calorimetric studies. Liposomes with the binary combination of 1,2-dipalmitoyl-sn-glycero-3-phosphatid...
Article
Application of the methods of the dilational surface rheology to adsorbed and spread layers of nano- and microparticles at liquid – fluid interfaces gives insight in the structure and formation mechanism of the layers. This is especially important in view of the limited applicability of standard experimental methods of the interface science to hete...
Article
Full-text available
This work is devoted to the dynamic properties of adsorption films of pulmonary surfactant and a spread monolayer of dipalmitoylphosphatidylcholine, which is the main component of the mixed surfactant. The surface dilatational elasticity of the aforementioned systems has been determined using a recently proposed approach, which is based on the anal...
Article
Full-text available
Purpose Orcinol glucoside (OG) - loaded nanostructured lipid carrier (NLC), coated with polyethylene glycol-25/55-stearate (PEG-25/55-SA), were explored for delivering OG to improve in vitro cytotoxicity against gastrointestinal tract (GIT), colon and hepatoma carcinoma cell lines. It is being expected that the PEGylated formulations would possess...
Article
Hypothesis: The adsorption kinetics of heptadecafluoro-1-nonanol (C9H2F17OH) onto a clean air-water interface at low surfactant concentrations (equilibrium surface tension, γ(C) > 65 mN/m) has been reported, and the controlling mechanism was found to be mixed diffusive-kinetic controlled (Kuo et al., JCIS 402 (2013) 131). However, it remains to be...
Article
Full-text available
The application of protein deuteration and high flux neutron reflectometry has allowed a comparison of the adsorption properties of lysozyme at the air–water interface from dilute solutions with and without strong denaturants, urea and guanidine hydrochloride (GuHCl). The surface excess and adsorption layer thickness were resolved and complemented...
Article
A new approach to the analysis of nonlinear surface dilational rheological properties was developed with the aim to enlarge the accessible range of surface pressures. The dilational surface elasticity of spread monolayers of DPPC, cholesterol, DMEA and their mixtures was determined in the region of low surface tensions (less than 10 mN/m) correspon...
Article
Development of drug delivery systems, not the drug discovery, has become more cynosures towards the efficacy of drug against the target cells. Modified hybrid cationic vesicles (HCV) were formulated using soylecithin (SLC), ion pair amphiphile (IPA, hexadecyltrimethylammonium-dodecylsulfate, HTMA⁺-DS⁻), bi-tail cationic surfactant dialkyldimethylam...
Article
The effect of the degree of dissociation on the adsorption kinetics of partially dissociated ionic surfactants was examined theoretically. The equilibrium and dynamic surface tension (ST) curves with different degrees of dissociation were theoretically generated for surfactants following the Langmuir adsorption isotherm. Two cases were examined. In...
Article
In this work we demonstrate the ability to tune the formation of extended structures in films of poly(sodium styrene sulfonate)/dodecyltrimethylammonium bromide at the air/water interface through control over the charge/structure of aggregates as well as the ionic strength of the subphase. Our methodology to prepare loaded polyelectrolyte/surfactan...
Article
The interactions between fibrinogen and polyelectrolytes in the surface layer of their mixed solutions were studied by measurements of the dynamic surface tension and surface elasticity as a function of surface age, polyelectrolyte concentration and solution pH. A flexible and negatively charged polyelectrolyte − sodium polystyrolsulfonate (PSS) –...
Article
Full-text available
Surface dilatational dynamic elasticity ε of films formed by cross-linked poly(N-isopropylacrylamide) microparticles on a water/air interface has been determined as a function of polymer surface concentration Γ. The experimental dependences exhibit two maxima of ε at surface pressures π of nearly 6 and 35 mN/m. In the region of the second maximum,...
Article
The review discusses the mechanism of formation of protein/surfactant adsorption layers at the liquid – gas interface. The complexes of globular proteins usually preserve their compact structure a low surfactant concentrations. Therefore a simple kinetic model of the adsorption of charged compact nanoparticles is discussed first and compared with e...
Article
The dynamic surface properties of mixed monolayers of 1,2-Dipalmitoyl-sn-glycerol-3-phosphocholine (DPPC) and negatively charged polystyrene particles (PS) of different size were investigated with the aim to model the interactions of particles with biointerfaces. Special attention was paid to the aggregation of the particles at the water/air interf...
Article
Measurements by capillary pressure tensiometry, under microgravity conditions aboard the International Space Station, supplied a consistent set of reliable results for the dynamic interfacial tension and for the interfacial dilational viscoelastic modulus, quantitatively characterizing the dynamics of Span-80 adsorbed layers at the paraffin-oil/wat...
Article
The surface properties of the solutions of two derivatives of C60 fullerene with lysine and arginine were investigated by measurements of surface tension, dilational surface rheological properties, characteristics of capillary waves, and by Brewster angle microscopy. It is shown that the adsorption of the derivatives is irreversible and they can fo...
Article
A pendant bubble tensiometer was used to measure the relaxation of the surface tensions of aqueous sodium dodecyl sulfate (SDS) solutions for four different perturbed air-water interfaces under surface rinsing, sudden surface compression, continuous surface expansion and compression. The complete set of surface tension (ST) relaxations was monitore...
Article
Full-text available
The dynamic surface properties of mixed solutions of a cationic surfactant - cetyltrimethylammonium bromide (CTAB) - and different types of deoxyribonucleic acid in both linear (ctDNA) and plasmid (pDNA) forms were studied by surface tensiometry and dilational surface rheology. The dynamic surface elasticity and the dynamic surface tension depended...
Article
The adsorption layers of complexes between DNA and oppositely charged surfactants dodecyltrimethylammonium bromide (DTAB) and cetyltrimethylammonium bromide (CTAB) at the solution/air interface were studied by the surface tensiometry, dilational surface rheology, atomic force microscopy, Brewster angle microscopy, infrared absorption reflection spe...
Article
Simultaneous measurements of the dilational dynamic surface elasticity and surface tension allow the tracing of the main changes in the adsorption layer structure of aqueous mixtures of gelatin with cetylpyridinium chloride (CPC). At low surfactant concentrations (<0.01 mM), the increase of the dynamic surface elasticity indicates the strengthening...
Article
Full-text available
Cystine-based gemini surfactants with dodecyl, tetradecyl, hexadecyl and octadecyl hydrocarbon chains were synthesized and their interactions with unsaturated (SPC) / saturated (HSPC) soyphosphatidylcholines in the forms of a monolayer and a model liposome were estimated at different combinations of the components in the mixed systems. Studies of L...
Article
Full-text available
Impact of saturation/unsaturation in the fatty acyl hydrocarbon chain on the physicochemical properties of nanostructured lipid carriers (NLC) were investigated to develop anticancer drug, ursolic acid (UA), loaded novel delivery systems. Aqueous NLC dispersions were prepared by high pressure homogenization-ultrasonication technique with Tween 80 a...
Article
The dynamic surface pressure Π and the two components E’ (real part) and E” (imaginary part) of the dynamic surface dilational modulus of adsorbed β-lactoglobulin (BLG) layers at the water/air interface were measured by oscillating drop/bubble profile analysis tensiometry with the aim to enlarge information on the surface rheology of solutions of t...
Article
We describe a new methodology to prepare loaded polyelectrolyte/surfactant films at the air/water interface by exploiting Marangoni spreading resulting from the dynamic dissociation of hydrophobic neutral aggregates dispensed from an aqueous dispersion. The system studied is mixtures of poly(sodium styrene sulfonate) with dodecyl trimethylammonium...
Article
Full-text available
Disulfide bond shuffling in the presence of the reducing agents dithiothreitol (DTT) or β-mercaptoethanol (BME) strongly affects the surface properties of lysozyme solutions. The addition of 0.32 mM DTT substantially alters the kinetic dependencies of the dynamic surface elasticity and surface tension relative to those of pure protein solutions. Th...
Article
The dynamic surface pressure Π of air bubbles aging in buffered β-lactoglobulin (BLG) solutions containing various protein concentrations CBLG (10−9–10−4 M), pH (3–7) and buffer concentrations Cbuff (1, 10 and 100 mM) was measured as a function of time t by bubble profile analysis tensiometry. Adsorption kinetics was studied by recording Π(t) data...
Article
Despite its widespread use in the determination of adsorption mechanisms and the estimation of surfactant diffusivity, the short-time approximation method, used for linearly fitting experimental dynamic surface tension data, should be validly applied only over a very specific range of time intervals or surface pressures. Therefore, the definition o...
Article
Guanidine hydrochloride and urea have different effects on the surface properties of lysozyme solutions due to different interaction mechanisms between the protein and denaturants: an increase in the guanidine hydrochloride concentration leads to noticeable changes in the dynamic surface elasticity, while the main effect of urea consists in a signi...
Article
The review concerns main achievements in dilational rheology of polymer adsorption films at the gas/liquid interfaces reported in the last fifteen years. The theoretical foundations of methods of surface rheology and the key results obtained in studies of solutions of amphiphilic nonionic polymers, polyelectrolytes, proteins and their complexes wit...
Article
Urea and guanidine hydrochloride (GuHCl) have different influence on surface properties of lysozyme solutions. The increase of GuHCl concentration leads to noticeable changes of kinetic dependencies of the dynamic surface elasticity and ellipsometric angles while the main effect of urea reduces to a strong drop of the static surface tension. The di...
Article
Full-text available
A study of the dilational surface viscoelastic properties of mixed solutions of lysozyme and denaturing agents of different chemical nature allows us to characterize the changes of protein tertiary structure in the surface layer upon adsorption at the liquid–gas interface. We show that guanidine hydrochloride (GuHCl) and urea influence the dynamic...
Article
The kinetics of dynamic surface elasticity of the mixed solutions of bovine serum albumin and synthetic polyelectrolytes makes it possible to apply dilational surface rheology to the determination of the adsorption mechanism of protein/polyelectrolyte complexes and the structure of adsorption layers.
Article
The dependence of the dilational surface elasticity on the surface pressure of the spread monolayers of polystyrene microparticles is studied at the water-air interface. The surface rheological measurements together with the data from optical methods allow the division of the whole range of surface pressures into three zones characterized by differ...
Article
We discuss different non-equilibrium mechanisms by which bulk aggregates directly modify, and can even control, the interfacial structure and morphology of an oppositely charged polyelectrolyte/surfactant (P/S) mixture. Samples are categorized at the air/water interface with respect to the dynamic changes in the bulk phase behavior, the bulk compos...
Article
The interfacial tension response to dilational deformation of interfacial area exhibits a (more or less) nonlinear behavior, depending on the amplitude of the deformation. Studies of such observable interfacial properties in the nonlinear domain suggest valuable information about the two-dimensional microstructure of the interfacial layer, as well...
Article
Dynamic surface elasticity of solutions of bovine serum albumin (BSA)/sodium polystyrene sulfonate (PSS) complexes has been measured as depending on the age of a surface, polyelectrolyte concentration, and solution pH by the oscillating-ring method. At pH values below the isoelectric point of BSA, the rate of variations in the surface properties in...
Article
This short review is devoted to recent achievements in studies of the dilational surface rheological properties of the systems containing complexes of silica nanoparticles with conventional surfactants. It is shown that there is a surfactant concentration range where the dynamic surface elasticity reaches extremely high values up to 1000 mN/m. This...
Article
The dynamic surface elasticity of mixed solutions of bovine serum albumin (BSA) and poly(diallyldimethylammonium chloride) (PDADMAC) was measured as a function of the surface age, polyelectrolyte concentration and solution pH. The addition of polyelectrolyte does not influence the dynamic surface properties of protein solution at pH below the isoel...
Article
The dilational surface rheology is applied to solutions of globular proteins (bovine serum albumin and β-lactoglobulin) in presence of urea. The kinetic dependencies of the dynamic dilational surface elasticity become non-monotonic if the denaturant concentration exceeds a certain critical value indicating the adsorption of unfolded protein molecul...