Bogdan Gutyj

Bogdan Gutyj
Stepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies Lviv · Department of Pharmacology and Toxicology

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231
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Publications

Publications (231)
Article
Based on the analysis of literature sources, monitoring results and our own research, it has been established that viral enteritis occupies a leading place in the infectious pathology of dogs and causes significant damage to animal owners. Viral enteritis, most commonly caused by parvovirus, causes severe gastrointestinal disorders and is one of th...
Article
Avian influenza viruses (AIVs) are spread globally by wild migratory birds that are reservoirs of AIVs. Epidemics of highly pathogenic avian influenza (HPAI) can devastate the poultry industry and result in severe trade restrictions. Many routes of wild migratory birds pass through the territory of Ukraine, therefore studying the circulation of the...
Article
The active substance of the drug “Vitosept” is high-purity sodium hypochlorite (HPSH), obtained by the direct electrochemical reaction on a newly developed diaphragm-free flow cell, bypassing the formation of molecular chlorine. The developers (Altapharm, Dnipro) used an isotonic (0.9 %) sodium chloride solution prepared in water purified by specia...
Article
In the conditions of modern man-caused pollution of the environment, environmental problems, as well as improving the quality of livestock products and their food safety, are important and relevant issues today. The study aimed to investigate the effect of the “Metisevit Plus” feed additive on bull blood's morphological and biochemical parameters u...
Article
The main infectious agent that causes contamination of poultry products are bacteria of the genus Salmonella. The article presents the results of monitoring studies on salmonellosis among poultry of different technological direction of poultry farms of all forms of ownership in Ukraine. In the analysis of the results of the incidence of salmonellos...
Article
The article presents the results of studies of caecum samples (cecal appendages) with contents from cattle, pigs, and poultry following the State Monitoring Plan for Antimicrobial Resistance in Veterinary Medicine for 2021, isolated and identified isolates of zoonoses and commensal microorganisms, namely: Escherichia coli, Salmonella spp., Enteroco...
Article
The tone of the autonomic nervous system is one of the key systems of the nervous system in regulating homeostasis. In turn, this can affect the metabolism of organic substances in the animal's body, which is reflected in physiological indicators. The aim of the study was to determine the influence of the tone of the autonomic nervous system on the...
Article
Processed cheeses have always aroused great interest and liking in a significant part of the population. They can be used for business trips, numerous picnics, and to prepare many dishes that could not be done without them. Another advantage of processed cheeses is their low cost. Therefore, in modern nutrition, processed cheeses have occupied a si...
Article
Today, the number of indicators that control the mineral nutrition of poultry has increased significantly. However, the physiological need of different species of poultry for some mineral elements that perform important biochemical functions in the body has not yet been definitively established. This also applies to such abiotic elements as seleniu...
Article
The aim of the research and production study was a systematic analysis – monitoring the dynamics of changes in productivity and technological indicators during five or six consecutive lactations in cows with long service life in the industrial dairy complex. The analytical part of the study was conducted during 2016–2021 on the basis of a dairy ent...
Article
The article presents the results of research on the reproductive qualities of sows of large white breeds of different interbreeding differentiation according to some evaluation indices, determines the criteria for selection of highly productive animals, and the economic efficiency of their use. Based on experimental data, Annex 10 to the Guidelines...
Article
The paper presents the study results of the indicators of individual development of Ukrainian gray, Ukrainian meat, and light Aquitaine breeds, biochemical indicators of blood serum, and also calculated the level of correlations between traits. The research was carried out at the State Enterprise “Experimental Farm “Polyvanivka” and the Animal Husb...
Article
A large number of water sources were found on the territory of Ukraine. Water sometimes has healing properties, but spring water's quality and “purity” cannot be guaranteed. It depends not only on people's daily activities but also on the location of the source. On the territory of the city of Lviv, there are several springs, the water used by the...
Article
Sodium hypochlorite is the active ingredient in the antiseptic “Vitosept”. The pharmacological activity of the newly created drug is due to Oxygen, which is released in the active state by the decomposition of unstable hydrochloric acid into hydrochloric acid. A study of the antiseptic effect of the drug Vitosept, conducted on a model of stencil wo...
Article
The mineral elements contained in poultry feed do not fully meet their needs. Therefore, the elements that are lacking in the diet are introduced into the feed or feed mixtures to ensure mineral integrity. The aim of the experiment was to research the cobalt chelate complex effect on live weight, weight gain, slaughter quality and hematological par...
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Full-text available
The formation of the parasite fauna of wild ungulates and control of diseases caused by them is an essential veterinary measure in the breeding of deer. The study aimed to conduct monitoring studies on the infestation of red deer parasites (Cervus elaphus) during commercial cultivation during acclimatization in the Western Polissya of Ukraine. Faec...
Article
The study aimed to establish the parameters of chronic toxicity of the newly developed drug based on phosphodiesterase-3 inhibitor and ethylmethylhydroxypyridine succinate in experiments on laboratory animals. The analysis was performed on white sexually mature young male Wistar rats weighing 170–185 g. Four groups of white rats were formed. The fi...
Article
The attention of modern society to euthanasia has increased because many centuries ago, a social phenomenon was established, associated not only with the achievements of medical science but also with changing values of the individual and society, actualizing the problem, considering them family members. The number of euthanasia animals has fallen s...
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Due to the study of the toxicity of 1,2,4-triazole derivatives by non-experimental methods using GUSAR and TEST models, it was found that the test compounds could be classified as low-toxic substances. The compound is an organic salt that exists in the crystal as a solvate with one molecule of methanol and two molecules of water. When studying the...
Article
One of the most actual problems of modern poultry farming is to increase the preservation of chickens and ensure high intensity of their growth at all stages of rearing. The development of alternative methods of prevention and treatment of infectious diseases of poultry involves the use of preparations of natural or organic origin, which have antag...
Article
Bovine leukemia and equine infectious anemia are registered in most regions of Ukraine and in many countries worldwide. This is accompanied by economic losses and reduced quality of livestock products, which determines the relevance of the study of retroviral infections, their diagnosis, and pathogenesis. The goal of our research was to find and im...
Article
The paper deals with the results of the search for fattening and meat qualities of young pigs of Large White breeds of different interbreeding differentiation according to some integrated indicators, the level of correlations between traits, and the economic efficiency of research results is calculated. The experimental part of the work was perform...
Article
Nanotechnologies are developing continuously, and their use is becoming more diverse and concrete, with high potential to improve the products of animal husbandry and animals in general. Yet, there have been few studies of nanotechnologies in those spheres. However, to confirm the efficiency and, mainly, safety of nanotechnologies, to avoid any har...
Article
Respiratory organs and cardiovascular system are interconnected and perform extremely vital functions of the organism, the main goals being performing gas exchange with the environment and emitting carbon dioxide produced in the organism into the environment. Therefore, we carried out comparative histo- and cytomorphometric evaluation of morphologi...
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The study aimed to investigate the effect of the drug “Bendamine” on dogs' clinical and morphological parameters in heart failure. Two groups of dogs were formed for research: control (healthy) and experimental (sick). The 30-day experiment included ten dogs from the control group, ten dogs of the observed (unhealthy) spaniel breed, and 10–12 years...
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The main task of this study consists in evaluating the state of funding for environmental protection measures and substantiating the ability of the state and local communities to increase investments in environmental protection. To this end, the following was studied from 2010 through 2020: 1) mechanisms of filling and using funds of the Environme...
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Coordination of physiological activity and intensity of metabolism in various organs and tissues of a productive animal, depending on environmental conditions and own needs, is provided by the regulatory activity of the corresponding nerve centers. However, the features of the autonomic regulation of the nervous system in this matter can have a sig...
Article
One of the conditions for obtaining high-quality pig products is the use of feed additives, which contain all the necessary biologically active substances, eliminating their deficiency in feed and acting as catalysts for metabolic processes in pigs. That is why the aim of the study was to study the effect of feed additive “Sylimevit” on the enzymat...
Article
In dairy farms of Ukraine, where highly productive dairy cows are kept, liver lesions are often diagnosed in the postpartum period. Postmortem studies of the liver of cows that were forcibly slaughtered showed that in mostly animals were diagnosed with fatty degeneration of the liver. The main causes of fatty hepatosis were violations of the struct...
Article
The article deals with the influence of the use of means for young pigs Globigen® Pig Doser та Globigen® Jump Start, which due to the content of specific Ig Y have immunostimulatory properties. Assessing the level of nonspecific resistance of piglets, which are based on determining the content of T- and B-lymphocytes and their populations in the bl...
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Full-text available
The results of the studies on the determination of the optimal dose of the probiotic additive “Evitalia” (PAE) for the quails of the Texas breed have been presented in the article. The experiments were conducted on the quails aged 1–35 days. The object of the research was the probiotic additive “Evitalia” that consisted of eight components (the str...
Article
Fasciolosis is one of the most dangerous helminthiasis, causing significant economic damage to farms. Therefore, the study aimed to investigate the effect of clozaverm A and butaselmevit on the antioxidant status of cows in experimental fasciolosis. Fifteen 4-5-year-old cows of the black and speckled breed were selected for the experiments, from wh...
Article
The problem of toxocariasis is essential for both human and veterinary medicine. Therefore, the study aimed to determine the effect of fenbenzyl and fenbendazole on the morphological parameters of the blood of dogs, with experimental infestation with the pathogen toxocariasis. The experiments were performed on 18 dogs, two to four months of age, an...
Article
The research aimed to study the effect of additional protein feeding of foster families with buckwheat stalks. The research was conducted during the summer period in 2020 and 2021. Ten foster families were selected for the experiment. All families are chosen by the method of analogs. Bees were kept in beehives. The uterus of the Carpathian breed to...
Article
The article is a summary of the literature on the main aspects of the modern bird feeding system. Theoretical aspects and results of experimental research of scientists on the substantiation of parameters of protein and amino acid nutrition are given, which is an important factor that, under appropriate conditions can significantly guarantee the re...
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The most common problem among ready-made foods is the adulteration of butter, which is replaced by margarine or vegetable spreads. Milk and other dairy products made from raw milk are not left out. The production and sale of low-quality, counterfeit products poses a direct threat to human health and affects the competitive environment among produce...
Article
Reservoirs and ponds belong to specific objects of water resources. Most reservoirs and ponds are of anthropogenic origin. They are of special importance for the Lviv region due to its terrestrial properties. In modern conditions, the importance of reservoirs and ponds is growing significantly. This is due to the fact that in many areas they form n...
Article
The paper presents the results of the study of signs of long-term adaptation and indicators of reproductive qualities of sows of the universal direction of productivity, as well as calculates the economic efficiency of research results. The experimental part of the work was performed in the agricultural formations of the Dnipropetrovsk region and t...
Article
In recent years, based on new scientific data, many countries worldwide have been revising the existing standards for introducing trace elements in mixed feed for highly productive broiler chicken crosses. This also applies to selenium, which is recognized as an indispensable biotic ultramicroelement with a wide range of biological action according...
Article
Intensive pig breeding has been reported in the literature to suggest that early weaning of piglets from sows is an extreme stimulus that reduces the protective and adaptive responses of piglets. That is why the aim of the study was to study the effect of the feed additive “Sylimevit” on the level of lipid peroxidation products of piglets after wea...
Article
Full-text available
This experiment was conducted to study the effect of a prolonged hot period on the fatty acid (FA) composition in blood serum of dairy cows. Eighteen multiparous Holstein cows were randomly assigned to the hyperthermia group (HYP, n = 8) in August (summer season) and the control group (CON, n = 10) in October (autumn season). Blood from animals of...
Article
Of the total number of animal diseases, 70–80 % are non-communicable diseases, and more than 50 % are surgical diseases, which cause significant economic damage to the livestock industry due to reduced productivity and premature culling of livestock. Irrational, unbalanced in terms of macro- and microelements, vitamins, carbohydrates feeding leads...
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Full-text available
The high demand for protein during this period of the calf's life is due to the active growth of muscle tissue, and protein is the structural material of all organs. A lack of protein in the diet of calves contributes to a delay in their growth and an excess to the expenditure of additional energy for the deamination of excess amino acids and the e...
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The relevance of the article lies in the need to study artificial aquatic ecosystems, as uncontrolled anthropogenic impact is increasingly multifactorial and complex, characterized by a high degree of pollution, leads to irreversible changes in the structure of reservoirs, reducing the quality of the environment. This complicates the lives of all l...
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Interactions of productivity, content of separate amino acids, general protein in blood serum of chickens and tone of the autonomic nervous system. The regulation of metabolic processes and maintenance of a stable internal environment of the body is the role of the autonomic nervous system (ANS). It influences all systems and organs, thus along wit...
Article
Passalurus ambiguus (Nematoda, Oxyuroidae) is one of the most common parasites of digestive tract of domestic and wild rabbits and rodents. Passalurus spp. are cosmopolitan, and the mature nematodes are localized in the appendages and large intestine of animals. The passaluariasis infections remain quite relevant in modern rabbit breeding, because...
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Full-text available
The paper analyzes ecotourism's impact on the social, economic, and environmental components of sustainable development. A systematic review of the scientific literature on the topic reveals that the major problem in assessing ecotourism's impact is a lack of a unified approach to methods of measurement and certification in this field. Even approxi...
Article
The results of research show that the bait for the destruction of rats and mice «Biosan» rats eat willingly, completely. At simultaneous setting, in portable feeders, standard granulated feed and feed substrates of the manufacturer, rodents prefer the latter. On the 2nd day in experimental rats there was a slight inhibition of behavioral reactions,...
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Full-text available
Studies on the effectiveness of the inclusion of sodium humate in the diet of young cattle were conducted on four groups of animals. Installed improvement in the consumption of hay by the bulls of the experimental groups by 12.5-20 % compared with the control young was found, as a result of which they consumed more feed units by 1.5, 2.3, and 3.5 %...
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Finding livestock breeds that are resistant to high temperatures may be one of the strategies for mitigating the impact of global climate change on dairy farming. In this investigation, we studied the heat resistance of Holstein (HB) and Brown Swiss (BS) cows on two commercial dairy farms under the hot summer conditions of Ukraine. The physiologica...
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Full-text available
The tone of the autonomic nervous system, protein metabolism and the activity of the antioxidant system in Cobb-500 cross chickens aged 35 and 60 days were researched. The experiment involved 24 chickens, 8 in each group. In birds, the tone of the autonomic nervous system was determined by the method of variation pulsometry by recording the influen...
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Full-text available
In the present study, we observed in vitro the rate and stages of exogenous development of the nematode Trichuris sylvilagi Tiner, 1950 isolated from the European hare, Lepus europaeus. The viability of eggs and embryos at different temperatures was investigated. It was found that the most favorable temperature for embryonic development of the spec...
Article
«Kolidev 8M» (powder for oral use) is a veterinary drug used to treat ornamental birds (pheasants, peacocks) in diseases of the digestive tract caused by microorganisms sensitive to colistin. In the study of the drug «Kolidev 8M» for oral administration, along with the confirmation of therapeutic properties, it is necessary to determine the LD50 ob...
Article
The aim of the study was to investigate the effect of the feed additive “Butaselmevit-plus” on the state of the antioxidant defense system of piglets during weaning. The experiments were conducted on the basis of the LTD “KOSHET” Mukachevo district of Zakarpattia region. Two groups of piglets were formed – control and experimental, in the amount of...
Article
Full-text available
The tone of the autonomic nervous system, protein metabolism and enzymes in Cobb-500 crossbred chickens aged 35 and 60 days were studied. The experiment involved 24 chickens, 8 in each group. In birds, the tone of the autonomic nervous system was determined by the method of variation pulsometry. The essence of the method is to record the effect of...
Article
Full-text available
The results of morpho-biochemical studies of tuberculosis inflammation in rabbits in an experimental model with comparative isoniazid treatment and N'-(2-(5-((theophylline-7-yl)methyl)-4-ethyl-1,2,4-triazole-3-ylthio)acetyl)isonicotinohydrazide. It was found that subcutaneous administration of N'-(2-(5-((theophylline-7-yl)methyl)-4-ethyl-1,2,4-tria...
Article
Prolonged ingress of heavy metals into the organisms of animals, even in low concentrations, causes a number of toxic impacts, affecting various organs and systems. The objective of this study was to research parameters of enzymatic and non-enzymatic links of the system of antioxidant protection of the organism of young cattle in the condition of l...
Article
Microsporіа affect different species of animals and humans. The high contagiousness of the pathogen determines the relevance of research into this disease. Microsporum canis is the pathogen that most often causes microsporia. Weakened functions of the immune system and violation of the epithelial barrier of the skin are a favourable factor that cau...
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Сolloquium-journal №12(99), 2021:12-16 Catalase is one of the main enzymes of anti-radical protection of animals and humans. It removes peroxide of hydrogen by converting it to water and oxygen. Tocopherol is involved in antioxidant protection due to its ability to capture peroxide radicals' unpaired electrons and inhibit lipid peroxidation reactio...
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Full-text available
The most practical methods of detoxication of mycotoxins in animals and poultry are based on damaged feed sorbents. The search aims to study the influence of HamecoTox on the morphological and biochemical indices of the blood of laying hens in spontaneous fumonisin toxicosis. Laying hens (ferrets, aged 78 weeks) of cross Highsex White, with an aver...
Article
Using nanotechnologies to obtain compounds of mineral substances is promising because of the importance of the amount of mineral substances, but the limiting factor is particularly their bioavailability in the digestive tract. The conducted studies determined the stimulating effect of nanoaquachelates of separate biogene microelements on the course...
Article
The basis of the technology of functional foods, as is known, is the presence of high content of nutrients, the ability to influence certain parts of the potential consumer. Fermented milk products in this regard are natural representatives of this group. The use of sour milk drinks with phytonutrients of different physical state will contribute no...
Article
There are a number of springs on the territory of Lviv, water from which is used by the city residents. It should be noted that natural resources cannot be systematically used by the population for drinking purposes, as they are not sources of centralized water supply and, accordingly, do not have service personnel. No sanitary protection zones hav...
Article
The results of research activities of reproductive qualities of sows of different breeding value are given, the level of their phenotypic consolidation is determined and the correlation analysis is carried out. The study was conducted in agricultural formations of Dnipropetrovsk and Sumy regions (LLC “AF “Renaissance”, research farm of the Institut...
Article
The general trends in the purity changes of the environment in connection with the urbanistic technogenesis were analyzed on the example of the largest city of Western Ukraine – Lviv – and its outskirts, Dublyany. The characteristic changes of some parameters of the main environmental factors – transformed ecosystems, including biogeochemical prope...
Article
The article presents the results of determination of acute and subacute toxicity of the drug “Tilovet 20 %”, which was made on the basis of tylosin tartrate. In result of the conducted researches, it was found out, that LD50 of the drug “Tilovet 20 %” by intramuscular injection to white mice (calculated by the method of G. Kerber) is 10000 and mg/k...
Article
Experimental studies obtained in recent years indicate the urgency of developing drugs of complex action to prevent the development of cardiovascular disease in dogs. This requires a much deeper study of the pathogenesis of heart failure, including cardiomyopathy. The aim of the study was to investigate the effect of the drug “Bendamin” on the bioc...
Article
Toxocariasis is a chronic helminthic disease caused by the larval stages of the nematode Toxocara canis. The problem of toxocariasis is important for both humane and veterinary medicine. Therefore, the aim of the study was to investigate the effect of fenbenzyl and fenbendazole on the intensity of lipid peroxidation in the blood of dogs during expe...
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Full-text available
The article analyzed the state of environmental taxation in Ukraine to assess the degree of implementation of environmental, fiscal, and incentive functions. For this purpose, the analysis is carried out the dynamics of environmental tax revenues to the consolidated budget of Ukraine in the context of the receipt of funds to state and local budgets...
Article
The article deals with the concentration changes and relative content of bacterial cells of Desulfuromonas acetoxidans in the intervals of sizes 0.2–2.0 µm under the influence of nano silver particles. Correlation between these changes of light-scattering properties of bacterial cells and growth abilities of bacteria Desulfuromonas acetoxidans unde...
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In this study, no toxic effects were detected after single subcutaneous injection of 40 mg/kg tadpoles. The results of macro-and microscopic examination of the internal organs 14 days after single subcutaneous administration of N'-(2-(5-((thephylline-7'-yl)methyl)-4-ethyl-1,2,4-triazole-3-ylthio)acethyl)isonicotino-hydrazide (GKP-305) at a dose of...
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Full-text available
The problem of tuberculosis infection caused by multidrug-resistant strains is becoming increasingly important in the world. This infectious disease poses a global health risk with an incidence rate of 8.8 million cases and a fatal outcome of 1.4 million. Coinfection with human immunodeficiency virus (HIV) increases the number of cases of tuberculo...
Article
Full-text available
The problem of tuberculosis infection caused by multidrug-resistant strains is becoming increasingly important in the world. This infectious disease poses a global health risk with an incidence rate of 8.8 million cases and a fatal outcome of 1.4 million. Coinfection with human immunodeficiency virus (HIV) increases the number of cases of tuberculo...