Blazenka Miskic

Verified

Blazenka verified their affiliation via an institutional email.

Learn more

Verified

Blazenka verified their affiliation via an institutional email.

Learn more

• Prof. of Internal Medicine
• Professor (Full) at University of Osijek

Background: The Infertility refers to the inability of couples to conceive after 12 months of regular, unprotected sexual intercourse. The incidence of infertility is increasing and is estimated to be 8-12%, or even up to 20%. Primarily, it involves organic causes, but the psychological aspect is not excluded. Objective: The aim of this article was...

Background/Objectives: Ego defense mechanisms are subconscious processes that help individuals cope with stressors from both external and internal realities. They are divided into three levels based on their adaptive function. Patients undergoing chronic hemodialysis are those who have been treated with this method for longer than three months. Onl...

Abstract Introduction Intestinal inflammation and gut microbiota dysbiosis can stimulate degeneration of dopaminergic neurons and development of Parkinson's disease (PD) via the gut-brain axis in certain patients. Methods In a case-control study, fecal markers of intestinal inflammation and permeability were measured using the ELISA method in PD p...

Given in reperfusion, the use of stable gastric pentadecapeptide BPC 157 is an effective therapy in rats. It strongly counteracted, as a whole, decompression/reperfusion-induced occlusion/occlusion-like syndrome following the worst circumstances of acute abdominal compartment and intra-abdominal hypertension, grade III and grade IV, as well as comp...

Background: Osteoarthritis (OA) is a progressive degenerative disease with an inflammatory background. Chronic myeloproliferative neoplasms (MPN) are clonal hematopoietic disorders characterized by chronic inflammation and a tendency for connective tissue remodeling. Aim: This study aimed to investigate the prevalence and associated risk factors of...

Funding Acknowledgements Type of funding sources: None. Cardiovascular disease and Cancer are the leading causes of mortality in the world. This is due to the aging of the population and the fact that most of the classic cardiovascular risk factors also predispose to cancer. Cardiovascular disease is the most common cause of late morbidity and mort...

Background: Prediabetes is a disordered state of glucose metabolism defined by an elevated blood glucose level that is below the level required for the diagnosis of diabetes. Prediabetes is associated with an increased risk of cardiovascular disease. The onset and progression of macrovascular disease occur during the prediabetes phase. Early diagn...

All metabolic risks and complication of cardiovascular disease especially for diabetes mellitus type 2. Stratification and indication for all antihperglycemic therapy.

Introduction: Based on the hypothesis that there is a substantial rate of adults with prediabetes and undiagnosed diabetes mellitus (DM), our aim was to perform haemoglobin A1c (HbA1c)-based screening in a cohort of Croatian adults and estimate the prevalence of prediabetes and undiagnosed DM according to American Diabetes Association criteria. M...

Introduction: The aim of this study was to use cross-sectional research to determine the relationship between serum ferritin levels and arterial hypertension in women who work in shifts and women with regular daytime working hours.

The book describes the most important risk factors for the development of cardiovascular incidents in patients with diabetes. CVOT studies and recommendations on the latest therapy of type 2 diabetes mellitus are presented, as well as ways of its prevention and effective treatment.

Obesity is a multifactorial chronic disease characterized by the excessive accumulation of fat in adipose tissue driven by hypertrophy and hyperplasia of adipocytes through adipogenesis. Adipogenesis plays a key role in the development of obesity and related metabolic disorders, which makes it potential target for the therapeutic approach to obesit...

The book describes the most important risk factors for the development of cardiovascular incidents in patients with diabetes. CVOT studies and recommendations on the latest therapy of type 2 diabetes mellitus are presented, as well as ways of its prevention and effective treatment.

Proceedings of final graduate and undergraduate theses of the Faculty of Dental Medicine and Health, students of OB Dr Josip Benčević Sl.Brod

Introduction: Rifampicin is currently used to treat various bacterial infections, with the most significant application in the treatment of tuberculosis. Dose-independent side effects of the drug can lead to the development of various coagulation disorders, among which disseminated intravascular coagulation is the most nagerous. The mechanism of co...

Aim: Takotsubo cardiomyopathy is a transient dysfunction of the heart muscle that occurs in response to a stressful event. A working diagnosis is mostly made for acute ischemic heart disease due to similar clinical presentation and differential diagnostic doubts. Although it is a reversible disorder of cardiac contractility, mortality rate is simil...

COVID-19 pandemic has changed everyday life and medical supervision of chronically ill patients. Epidemiological measures, social distancing, and limited access to medical care impair glycemic control in patients with diabetes. Also, type 2 diabetes is a risk factor for more severe form of coronavirus disease. A large proportion of diabetic patient...

Peripheral artery disease (PAD) is an occlusive disease of extremities, which used to be diagnosed and treated as an isolated disease of the limbs or other parts of the body. About 200 million people are affected by PAD worldwide. The prevalence of PAD is likely to increase steadily in the future due to the global aging of the population and the pr...

SUMMARY: Diabetes and its complications causes up to 9% of total mortality worldwide. Peripheral arterial disease is, in addition to cardiovascular diseases, the most common complication of diabetes with a prevalence that increases with age and the duration of diabetes. The specificity of peripheral artery disease in diabetics is the diffuse involv...

Abstract: Background: The aim of this study was to examine the impact of education, coronavirus disease 2019 (COVID-19), and risk factors on the quality of life in patients with type 2 diabetes. Methods: A prospective study was conducted in three phases: before education, after education, and in the period of pandemic coronavirus disease 2019 (COVI...

Handbook about diagnostic and therapeutic procedures with COVID-19 infection

Handbook about diagnostic and therapeutic procedures with COVID-19 infection

Obesity is recognized as a severe threat to overall human health and is associated with type 2 diabetes mellitus, dyslipidemia, hypertension, and cardiovascular diseases. Abnormal expansion of white adipose tissue involves increasing the existing adipocytes’ cell size or increasing the number through the differentiation of new adipocytes. Adipogene...

COVID-19 pandemic has changed everyday life and medical supervision of chronically ill patients. Epidemiological measures, social distancing, and limited access to medical care impair glycemic control in patients with diabetes. Also, type 2 diabetes is a risk factor for more severe form of coronavirus disease. A large proportion of diabetic patient...

Peripheral artery disease (PAD) is an occlusive disease of extremities, which used to be diagnosed and treated as an isolated disease of the limbs or other parts of the body. Nowadays, the role of PAD transcends the affected limb; instead, the cardiovascular system must be observed as a whole, with PAD having a prognostic role. About 200 million pe...

SAŽETAK: Novi koronavirus, nazvan virus teškog respiratornog sindroma (eng. Severe Acute Respiratory Syndrome Coronavirus-2, SARS-CoV-2), identificiran je u prosincu 2019. U slijedećim mjesecima, zahvaljujući obilježjima brzog i lakog prijenosa infekcije među ljudima, SARS-CoV-2 doveo je do pandemije s preko 2.000.000 oboljelih i preko 100.000 smrt...

Deskriptori INFEKCIJE KORONAVIRUSOM-komplikacije, virologija; BETAKORONAVIRUS; KARDIOVASKULARNE BOLESTI-farmakoterapija, komplikacije; ANGIOTENZIN KONVERTIRAJUĆI ENZIM-metabolizam; INHIBITORI ANGIOTENZIN KONVERTIRAJUĆEG ENZIMA-farmakologija, terapijska uporaba; BLOKATORI RECEPTORA ANGIOTENZINA II TIP 1-farmakologija, terapijska uporaba; RENIN-ANGIO...

Sažetak: Radna skupina Hrvatskog društva za dijabetes i bolesti metabolizma Hrvatskog liječničkog zbora pripremila je preporuke za postupanje u pandemiji COVID-19 za osobe sa šećernom bolešću i za zdravstvene djelatnike. U preporukama je naglašen razmjer pandemije i moguće posljedice za oboljele od šećerne bolesti. Opisana je klinička slika i ponov...

Aim of the Study: Silent acute myocardial infarction occurs commonly in diabetic patients. Currently, it is not fully understood whether altered perception of ischemia also predisposes atypical presentations, and therefore leads to under-diagnosing the acute myocardial infarction (AMI) in diabetic patients. In this study, we tried to determine whet...

Dom zdravlja Slavonski Brod 4 Nastavni zavod za javno zdravstvo Brodsko-posavske županije Sažetak Uvod: Jedan od ključnih čimbenika rizika za kardiovaskularne bolesti je hipertenzija ili povišen krvni tlak. Hipertenzija već pogađa milijardu ljudi širom svijeta, što dovodi do srčanih i moždanih udara. Komplikacije od hipertenzije godišnje bilježe 9,...

Sažetak Transplantacijska medicina omogućila je spašavanje i produljenje života mnogim ljudima. No, zamijeniti bolestan ili oštećeni organ zdravim moguće je samo zahvaljujući darivateljima organa. Pozitivan stav javnosti može doprinijeti povećanju svijesti o važnosti darivanja organa. Ciljevi rada su istražiti informiranost vinkovačkih srednjoškola...

The paper presents the guidelines made by the Multidisciplinary Team for Osteoporosis for patients in the General Hospital “Dr.Josip Benčević”, Slavonski Brod and general practitioners in the Brod-Posavina County in order to inform them properly about the COVID-19 pandemic and the recommendations of the National Civil Protection Committee, as well...

Background: The aim of this study was to examine the effect of dietary education on glycemic control in patients with any type of diabetes at four-week and two-year follow-ups. Methods: A two-year prospective study was conducted in three phases: before, four weeks after, and two years after an educational program. The participants were patients...

ciber bulling : the differnces between rural and urban enviroment

Local anti-inflammatory effect of vitamin D in acute and chronic gouty arthritis Blazenka Miskic, Ines Rajkovača, Vesna Cosic Abstract Background Vitamin D has immunomodulatory, anti-inflammatory properties and important role in bone metabolism. Effects of vitamin D supplementation in musculoskeletal diseases are well known, but it is unknown if lo...

Vitamin D deficiency is often found in patients with IBD. Vitamin D has immunomodulatory activity avoiding excessive immune response and has the function of repairing the intestinal mucosal barrier in IBD. Aims: determination level of vitamin D in patients with acute Chron's disease. Methods: We have analyzed 20 patients with Crohn`s disease at the...

PRIMARY DYSMENORRHEA AND VITAMIN D INSUFFICIENCY IN YOUNG WOMEN Co-authors B. Miskic1, V. Cosic2, I. Rajkovaca1, K. Cvitkusic-Lukenda3, M. Knezevic-Pravecek3. 1Faculty of Dental Medicine and Health- Osijek, of gastroneterologie- endocrinologie and diabetiologie-GH dr Josip Bencevic Sl.Brod, Slav. Brod, Croatia. 2Faculty of Dental Medicine and Healt...

Mini Review Multiple sclerosis (MS) is an autoimmune inflammatory disorder of unknown etiology affecting central nervous system (CNS)characterized by demyelination and variable degrees of axonal loss [1]. The etiology of MS is still unknown; however, it is believed to be caused by combination of immune dysregulation, genetic and environmental facto...

Air pollution is a big public health problem. Short term and long-term exposure to air pollutants have different health effects. The purpose of this research is to determine whether PM10, PM2.5, H2S and meteorological parameters have impact on frequency of urgent interventions in ERs (Institute of Emergency Medicine of Brod-Posavina County and Inte...

Objective: Vitamin D deficiency has been associated with cardiovascular disease. The aim of this study was to determine serum concentration of 25 hydroxyvitamin D (25(OH)D) in patients with acute coronary syndrome (ACS) and to assess the prognostic role of serum vitamin D level in ACS patients during 3-year follow up. Methods: The study included...

Glucocorticoids are a more prominent cause of secondary osteoporosis. They exacerbate reduced calcium absorption, decline in function and number of osteoblasts and osteocytes, increase the number and activity of osteoclast, which, with a deficit of 1.25 (OH) D3 and a decrease in muscle strength, lead to increased bone loss that later results in a f...

There is a known global vitamin D deficiency and its implications on a whole range of cellular processes. For the past 10 years, studies and meta analyzes have confirmed low serum levels of vitamin D3 in autoimmune, inflammatory, malignant, allergic and atherosclerotic processes. Interferes in stimulation of glucose and effect on insulin, modifies...

UVOD: Hipertenzija-tlak iznad 140/90mm hg se u trudnoći dijeli na kroničnu i gestacijsku. Kronična hipertenzija se javlja prije 20 tjedna gestacije u 1 do 55 svih trudnoća. Gestacijska hipertenzija se razvija nakon 20 tj trudnoće (obično nakon 37 tj) i povlači se 6 tjedana iza poroda. Pojavljuje se u 5 do 10 % trudnoća, češće u višeplodnim trudnoća...

Introduction: It is well known that vitamin D can modulate immunological state especially in Hasimotho thyroiditis.1 We estimated serum level of 25(OH)D3 at 16 women with Hashimoto thyroiditis and problem with misconception.2 All of them had three or more habitual abortion before. Aim: We wanted to estimate which serums level of vitamin D is necess...

Introduction: A low level of vitamin D accelerates the lack of immune tolerance on thyroid cells. High level of interleukins and chemotaxic factors contributed to inflamatory state. It’s presented with high level of antibody. We wanted to estimated level of vitamin D, level of Thyroid stimulate hormon ( TSH ) thyroid perioxidase antibody ( TPOAb) a...

Sažetak The aim of the study was to determine whether serum vitamin D level is lower in female patients with glaucoma as compared with control group. The mechanism by which vitamin D reduces intraocular pressure is not fully clarified. Almost all tissues possess vitamin D receptor (VDR). The mice lacking VDR (VDR knockout mice) have greatly contrib...

The aim of the study was to determine whether serum vitamin D level is lower in female patients with glaucoma as compared with control group. The mechanism by which vitamin D reduces intraocular pressure is not fully clarified. Almost all tissues possess vitamin D receptor (VDR). The mice lacking VDR (VDR knockout mice) have greatly contributed to...

AIM: We aimed to examine whether there is any association between serum levels of 25-hydroxyvitamin D [25(OH)D3] and silent urinary tract infection (UTI) among postmenopausal women. METHODS: Age, postmenopausal period, body mass index (BMI), White blood cell count, serum C-reactive protein, calcium, phosphorus, alkaline phosphatase, parathormone,...

Aim: We aimed to examine whether there is any association between serum levels of 25-hydroxyvitamin D [25(OH)D3] and silent urinary tract infection (UTI) among postmenopausal women. Methods: Age, postmenopausal period, BMI, white blood cell count, serum C-reactive protein, calcium, phosphorus, alkaline phosphatase, parathormone, serum 25(OH)D3 leve...

Objectives: Hyperprolactinemia is a common endocrine problem seen in everyday practice. Therefore, the Croatian society for endocrine oncology decided to write Croatian guidelines for the management of hyperprolactinemia that implements current scientific evidence with acknowledgement of economic and cultural specificities in Croatia. Methods: Thes...

The development of population policy and health legislation as a result of government, the need for more young, healthy, working and military active population, resulted in the education of all health workers including midwives, legal regulation of their work, increasing their number and training of midwifery profession. With the development of thi...

Aims: To determine the relationship of 25-hydroxyvitamin D (25(OH)D) serum concentration with acute coronary syndrome (ACS) with review on subgroup of diabetic patients. Methods: 60 patients age between 30 and 70 year treated for ACS: STEMI and NSTE-ACS at General Hospital in Slavonski Brod, Croatia, and 60 control subjects free from ACS including...

P135 VITAMIN D DEFICIENCY IN CHILDREN ENTERING PUBERTY, ACCIDENTAL OR REALITY? Aims: In the study which investigated the association of selected genetic polymorphisms and BMD in boys reaching puberty, we observed influence of nutrition and behaviour patterns on ultrasounds bone mineral parameters too. Methods: We analysed all ultrasound parameters...

SUMMARY: In Republic of Croatia the health care system existed in the late 18th century as primarily protection against infectious diseases. After its expanded to other segments of health population, including measures relating to maternity protection. We investigated the perinatal indicators in ''Brod na Savi“ in the 19th century. The history of p...

Abstract The aim of this study was to investigate the association of selected genetic polymorphisms and bone mineral density (BMD) in children reaching puberty and at the age of 18. The study sample consisted of 168 boys residing in Slavonski Brod, Croatia. Calcaneal quantitative ultrasound measurements were undertaken with Sahara device (Hologic)....

The development of population policy and health legislation as a result of government, the need for more young, healthy, working and military active population, resulted in the education of all health workers including midwives, legal regulation of their work, increasing their number and training of midwifery profession. With the development of thi...

INTROdUCTION: The extraskeletal effects of vitamin D in particular, its role in maintaining a healthy cardiovascular system are receiving increased attention. pATIENT ANd mEThOds: Patient group included 60 patients (40 male, mean age 58) presented to cardiology clinic with acute coronary syndrome (ACS) and underwent coronary angiography. Contro...

Uvod: S obzirom na to da ekstraskeletni ucinci vitamina D, posebice njegova uloga u održavanju kardiovaskularnog sustava dobivaju sve vise pažnje, cilj je bio odrediti serumsku koncentraciju vitamina D u ispitanika s akutnim koronarnim sindromom i u kontrolnoj skupini. Pacijenti i metode: U istraživanje su ukljuceni bolesnici lijeceni zbog akutnog...

Objectives: For the first time in Croatia we are determine serum levels of vitamin D in patients with acute coronary syndrome (ACS). Despite decreasing trends of coronary artery disease (CAD) in Croatia, only limited data are available on the relationship between vitamin D and CAD. Vitamin D deficiency has been linked to an increased risk of CAD an...

Abstract Meningiomas are benign neoplastic lesions of arachnoidal cells of the meninges. These tumors may arise wherever meninges exists, such as in the nasal cavity, paranasal sinuses, middle ear, and mediastinum. Optic nerve sheath meningiomas (ONSMs) are usually unilateral and occur predominantly in middle-aged females, although they may be pres...

We report the case of a 3-month-old boy with novel influenza A (H1N1) infection complicated by pericardial effusion. The patient was treated with pericardial drainage, oseltamivir, and ibuprofen and improved. Pericarditis and pericardial effusion have been occasionally associated with influenza A infections. To our knowledge, this is the first case...

Acute pericarditis is a well-recognized but rare complication of numerous viral infections. We report a case of a 50-year-old woman with novel inluenza A (H1N1) infection complicated by pericardial effusion. Resolution of both symptoms and pericardial effusion occurred after a treatment with oseltamivirin and ibuprofen. There were no signs of acute...

ABSTRACT A candidate identification questionnaire (CIQ) was tested to determine its predictive value for patient-reported satisfaction in patients switched from once-weekly or once-daily treatment with a bisphosphonate to once-monthly dosing. This was a prospective, open-label, multicenter international study in patients with postmenopausal osteopo...

We present an adolescent boy with unilateral supernumerary breast. It was a V type by Leung Clasification. Despite the average occurence between 0.22% and 6% in a normal population we have not had other cases in the last 20 years. The patient was an asthenic boy of sixteen in the IV stage of puberty. Sometimes he felt swelling and tenderness in thi...

Glycated hemoglobin A1C reflects a mean glycemia over the preceding 3 months (erythrocyte life span). In diabetes management, target value is set below 6.5%, to reduce the risk of chronic complications. However, there are different conditions that lead to a shortened lifespan of erythrocytes, resulting in falsely low HbA1C value. Case presented inv...

A prospective, open-labelled, multicentre 6-month study was designed to assess three categories that have high impact on Health-Related Quality of Life (HR-QoL). These categories were: satisfaction, preference and drug tolerability in postmenopausal patients with osteoporosis in Croatia, at first treated with weekly oral bisphosphonates, followed b...