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Publications (98)
Background
Recent evidence from both randomized controlled trials and cohort studies in adults suggests that plasma remnant cholesterol (RC) levels predict cardiovascular disease. In children, studies are scarce, although high levels of RC might represent a marker of early atherosclerotic damage. Thus, the aim of this study was to explore the cardi...
Introduction
Long COVID patients experience a decrease in their quality of life due to the symptomatology produced by the disease. It is also important to understand how long COVID affects both men and women. The objective of this study is to examine the impact of long COVID symptomatology on the quality of life of Spanish adults from a gender pers...
Background: Climate change represents a serious threat to the health of the population. Nurses are the ideal group to act on the health risks posed by climate change. However, their perception of this phenomenon is unknown, as existing studies are very scarce. An in-depth study of nurses’ perceptions of climate change is needed. For this purpose, q...
Background
Altered sleep parameters, such as duration and quality, play an important role in the pathogenesis and progression of cardiovascular diseases, as well as in all-cause morbidity and mortality. It has been suggested that the specific mechanisms underlying this association could be through the influence of sleep parameters on vascular marke...
Accumulating evidence supports the benefits of intermittent fasting (IF) as a dietary strategy for cardiometabolic health and weight control. However, little is known about the potential implications of IF on mental disorders. The aim of this review was to synthesize evidence regarding the effects of IF on mental disorders (depression, anxiety, and...
Context:
The importance and benefits of breastfeeding in children are well recognized, and it may improve motor development. Motor skills are fundamental to childhood development. Although some studies report a positive association between breastfeeding and motor development in children, others have suggested that these differences could be influe...
[This corrects the article DOI: 10.3389/fcvm.2022.798934.].
Arterial stiffness, a significant prognostic factor of cardiovascular disease, may be affected by dietary factors. Research on the effects of oral vitamin supplements on arterial stiffness and/or endothelial function has produced controversial results. Therefore, the aim of this network meta-analysis was to comparatively assess the effect of differ...
Background
Carotid structural changes measured by intima media thickness (IMT) have been related to cognitive complaints during aging. Therefore, the aims of this meta‐analysis were (1) to elucidate the relationship between vascular status, measured as IMT, and cognitive domains distinguishing between global cognition, executive functions, memory a...
Background
Arterial stiffness is an independent predictor of cardiovascular and all-cause mortality that is classically regarded as a consequence of arterial hypertension. However, a growing number of studies have shown that arterial stiffness is involved in the pathogenesis and prognosis of arterial hypertension. Thus, in this systematic review an...
(1) Background: Arterial stiffness is closely and bi-directionally related to hypertension and is understood as both a cause and a consequence of hypertension. Several studies suggest that antihypertensive drugs may reduce arterial stiffness. Therefore, effective prescription of antihypertensive drugs should consider both blood pressure and arteria...
Introduction
The main treatment for sleep apnoeas and hypopnoeas syndrome (SAHS) is continuous positive airway pressure (CPAP). However, patients sometimes do not adhere to the treatment protocol. Supplementary and complementary therapies have appeared as alternatives. Some of the therapies which are especially important are those related to myofun...
Aims
One of the most important mechanisms by which smoking contributes to cardiovascular disease is endothelial dysfunction, including arterial stiffness. However, the effects of smoking and smoking cessation on arterial stiffness remain unclear. This meta-analysis aimed to evaluate the effect of smoking and smoking cessation on arterial stiffness...
Purpose
To analyse: 1) the differences in health-related quality of life (HRQoL) between typically developing (TD) children and children with developmental coordination disorder (DCD) according to parents’ and children’s perception, and 2) the differences and level of agreement between parents and children’s perceptions in HRQoL in both children’s...
Background
Although brain-derived neurotrophic factor (BDNF) has been identified as a molecular biomarker of the neurophysiological effects induced by exercise, the acute effects of high-intensity exercise (HIE) on BDNF levels are inconclusive. This study aims to estimate the immediate effects of HIE on BDNF levels in healthy young adults.
Methods...
Background:
The fat but fit paradigm originally argues that the detrimental influence of obesity on cardiovascular risk and mortality could be counterbalanced by normal to high cardiorespiratory fitness (CRF) levels. The aim of the study was to determine whether there is a relationship between categories of the fat but fit conceptual model and heal...
Aims
Physical exercise has been associated with a reduction in arterial stiffness, a subclinical process underlying cardiovascular disease. However, the effect of different types of exercise (aerobic, resistance, combined, interval training, stretching, or mind–body modalities) on arterial stiffness is unclear. This network meta-analysis aimed to e...
Arterial stiffness has been shown to be a subclinical marker associated with cardiovascular disease. Meanwhile, long-term exercise has been demonstrated to reduce arterial stiffness, providing a decrease in cardiovascular risk. However, the acute effect of exercise on arterial stiffness is unclear. This systematic review and meta-analysis aimed to...
Background: Motor competence, defined as a person’s ability to execute different motor skills, is directly associated with children’s physical, mental, and social development and may be essential in encouraging an active lifestyle in childhood. Although health-related quality of life (HRQoL) in children has been described as an individual’s subject...
Evidence exists regarding the association between advanced glycation end products and different cardiovascular disease subclinical processes, such as arterial stiffness and atherosclerosis. With this systematic review and meta-analysis, we aimed to provide a synthesis of the evidence regarding the association of arterial stiffness measured by pulse...
Purpose:
To analyze the independent relationship between the risk of eating disorders and bone health and to examine whether this relationship is mediated by body composition and cardiorespiratory fitness (CRF).
Methods:
In this cross-sectional study, bone-related variables, lean mass, fat mass (by DXA), risk of eating disorders (SCOFF questionn...
Introduction
Cancer (and survival) is known to affect the quality of life. Strategies as physical activity and exercise during and after cancer may improve health-related qualify of life (HRQOL) outcomes and are, therefore, of clinical and public health importance. To the best of our knowledge, comparative evidence of the effect of the different ty...
Introduction
A growing interest has emerged on the effects of exercise during gestation. Several systematic reviews and meta-analyses have shown that prenatal exercise could reduce the mothers’ risk for some disorders. Despite this, evidence regarding the risk of caesarean section, birth weight or Apgar score at delivery is still controversial. Fur...
Introduction
The recommendations of most health organisations encourage mothers to keep exclusive breast feeding during the first 6 months and combining breast feeding with complementary feeding at least during the first and second years, due to the numerous immunologic, cognitive developmental and motor skill benefits that breast feeding confers....
Introduction:
The purpose of this protocol is to provide a network meta-analysis methodology that compares the effects of metformin and physical exercise in the prevention and treatment of gestational diabetes mellitus (GDM) and its associated fetal and maternal morbidity.
Methods and analysis:
This protocol conforms to the Preferred Reporting I...
Introduction:
The purpose of this study protocol is to provide the methodology for a review to compare the effect of statins vs physical exercise interventions and the effect of different types of physical exercise, on reducing arterial stiffness associated with cardiovascular diseases and mortality.
Methods and analysis:
The literature search w...
Growing evidence has accumulated in recent years showing that movement behaviors have important implications for health in children, especially for cardiovascular health, whose risk factors could track from childhood to adulthood. However, these findings are mixed and inconsistent in children. The aim of this study was to examine the relationship b...
Introduction
Orthorexia nervosa (ON) is characterized by an obsession with healthy eating, which may lead to severe physical, psychological and social disorders. It is particularly important to research this problem in populations that do not receive clinical care in order to improve early detection and treatment.
Objective
The aim of this study w...
Introduction
Peripheral arterial disease (PAD) is an underdiagnosed prevalent disease which implies high cardiovascular risk. Professionals usually depend on physical examination to screen for PAD.
Objective
To assess the diagnostic accuracy of physical examination to screen for PAD in a rural Primary Care population and to evaluate the nurse‐phys...
Background and aims:
The diagnostic performance of the oscillometric ankle brachial index (ABI) to detect peripheral arterial disease (PAD) varies among populations, suggesting a spectrum effect. When this heterogeneity modifies post-test probabilities, a spectrum bias arises. This study evaluates the presence and influence of spectrum effect and...
Sleep seems to have a significant influence on the metabolic syndrome (MetS). However, results in this association are still inconsistent in children. The aim of this study was to examine the influence of sleep characteristics in the MetS (index and factors) in Spanish children. Cross-sectional study including a sample of 210 children aged 8-to-11-...
Henni et al. have commented our recently published paper about diagnostic performance of inter-leg systolic blood pressure difference (ILSBPD) to detect peripheral arterial disease (PAD). First, we have proved that oscillometric errors are almost inherently linked to low ankle pressure or calcification. Since calcification usually implies obstructi...
Purpose: Inter-arm systolic blood pressure differences (IASBPD) and inter-leg systolic blood pressure differences (ILSBPD) have arisen as potential tools to detect peripheral artery disease (PAD) and individuals at high cardiovascular risk. This study aims to evaluate the diagnostic accuracy of IASBPD and ILSBPD to detect PAD, and whether IASBPD or...
Introduction:
Peripheral arterial disease (PAD) remains underdiagnosed and undertreated, partly because of limitations in the Doppler ankle-brachial index (ABI), the non-invasive gold standard.
Objective:
This systematic review and meta-analysis aims to compare the diagnostic accuracy of the oscillometric ABI and the Doppler ABI, and to examine...
Background:
Obesity and overweight during pregnancy have been negatively associated with fetal and offspring neurodevelopment. The aim of this systematic review and meta-analysis was to assess the effect of the relationship between pre-pregnancy overweight and obesity with children's neurocognitive development.
Methods:
We systematically searche...
In this cross-sectional study, we analyzed the relationship between resilience, cardiorespiratory fitness, and mental health-related quality of life, and examined whether resilience acts as a mediator between the latter two. The study included 770 university students, aged 18-30 years, from Cuenca, Spain. Anthropometric, sociodemographic, cardiores...
Background
The positive relationship between lean mass (LM) and bone health is well known, but a positive association between insulin and LM has also been described. Insulin has some anabolic properties on bone through the stimulation of osteoblast differentiation, yet the role of LM as a confounder or mediator in this relationship remains uncertai...
Study data.
(XLSX)
Background
Peripheral arterial disease (PAD) is an indicator of widespread atherosclerosis. However, most individuals with PAD, in spite of being at high cardiovascular risk, are asymptomatic. This fact, together with the limitations of the Doppler ankle-brachial index (ABI), contributes to PAD underdiagnose. The aim of this study was to compare os...
Bland and Altman plot testing for reliability in oscillometer.
Ten subjects (20 legs) were examined twice with oscillometer to calculate ABI. The differences between first and second measurements are plotted as a function of the average of the two measurements (n = 20). The solid line shows the mean difference with 95% confidence intervals.
(TIF)
Bland and Altman plot of oscillometer versus Doppler pressures in the arm.
The differences between methods are plotted as a function of the average of the two methods. The solid line shows the mean difference with 95% confidence intervals.
(TIF)
Bland and Altman plot testing for reliability in Doppler.
Ten subjects (20 legs) were examined twice with Doppler to calculate ABI. The differences between the first and the second measurements are plotted as a function of the average of the two measurements (n = 20). The solid line shows the mean difference with 95% confidence intervals.
(TIF)
2x2 Table of reference standard (Doppler) and index test (oscillometer) in ABI determination, excluding oscillometric errors and calcified legs.
Each leg is analyzed separately, thus making each leg an independent observation.
(PDF)
2x2 Table of reference standard (Doppler) and index test (oscillometer) in ABI determination, including calcified legs and oscillometric errors as PAD equivalents.
Each leg is analyzed separately, thus making each leg an independent observation.
(PDF)
STARD checklist of the study.
(DOCX)
Scatter plot of oscillometer vs Doppler pressures in the ankle.
The solid line shows the best regression line with 95% confidence interval. The equation shows the oscillometer pressure as a function of Doppler pressure.
(TIF)
Normal probability plot.
Distribution of the differences between oscillometric and Doppler ankle-brachial index readings.
(TIF)
Scatter plot of oscillometric and Doppler ABI.
The solid line shows the best regression line with 95% confidence interval, n = 151.
(TIF)
Scatter plot of oscillometer vs Doppler pressures in the arm.
The solid line shows the best regression line with 95% confidence interval. The equation shows the oscillometer pressure as a function of Doppler pressure.
(TIF)
Bland and Altman plot of oscillometer versus Doppler pressures in the ankle.
The differences between methods are plotted as a function of the average of the two methods. The solid line shows the mean difference with 95% confidence intervals.
(TIF)
Best cut-off determination for maximizing both the sensitivity and the specificity.
The best oscillometric cut-off was 0.956, with 87.3% of sensitivity and 91.2% or specificity.
(TIF)
2x2 Table of reference standard (Doppler) and index test (oscillometer) in ABI determination, excluding calcified legs and considering oscillometric errors as PAD equivalents.
Each leg is analyzed separately, thus making each leg an independent observation.
(PDF)
Objective:
The objectives of this study were to examine in university students: (a) the mean differences in the HRQoL among fat mass percentage, cardiorespiratory fitness (CRF) and sleep quality categories; and (b) the independent associations among fat mass percentage, CRF, and sleep quality with HRQoL.
Participants:
376 students, 18-30 years o...
Introduction:
Beverage consumption and its possible association with current obesity epidemic and metabolic syndrome is under investigation in recent years, however water intake is probably the most underestimated of all beverages and could play an important role.
Objective:
The aim of this study was to examine the association between water inta...
Introduction:
Beverage consumption and its possible association with current obesity epidemic and metabolic syndrome is under investigation in recent years, however water intake is probably the most underestimated of all beverages and could play an important role.
Objective:
The aim of this study was to examine the association between water inta...
Background:
Sleep disorders in schoolchildren are a common problem worldwide, and when are not adequately diagnosed and treated, their negative impact on daytime functioning may be significant. The aim of this study was to evaluate the psychometric properties of the Spanish version of the Children's Sleep Habits Questionnaire (CSHQ).
Methods:
Pa...
Apesar da importância da percepção da família na análise do atendimento em lares de idosos, praticamente não se fala neste aspecto. O objetivo deste estudo é identificar as preferências e as áreas de melhoria percebidas pelos familiares sobre os cuidados a pessoas com demência. Realizou-se um estudo qualitativo com base na Teoria Fundamentada, comb...
Background:
Our objective was twofold: to estimate the prevalence of underweight, overweight, and obesity in two birth cohorts (1999-2000 and 2007-2008) from Castilla-La Mancha, Spain; and to examine the association between parental socioeconomic status (SES) and weight status in these two cohorts.
Methods:
Cross-sectional analysis of baseline m...
Background:
Childhood obesity has become an alarming worldwide increasing public health problem. The earlier adiposity rebound occurs, the greater the risk of becoming obese during puberty and adolescence. It has been speculated about the potential influence of vigorous physical activity on modifying the age of onset of adiposity rebound. Moreover...
Background:
The relationship between physical activity (PA) and bone health is well known, although the role of percent body fat (%BF) and fitness as confounders or mediators in this relationship remains uncertain.
Objective:
To examine whether the association between PA and bone mineral content (BMC) is mediated by %BF and cardiorespiratory fit...
Objective
Muscular fitness levels have been associated with cardiometabolic risk in children, although whether body weight acts as a confounder or as an intermediate variable in this relationship remains controversial. The aim of this study was to examine whether the association between muscular fitness and cardiometabolic risk factors is mediated...
Background
Studies that have examined the impact of a physical activity intervention on cardiometabolic risk factors have yielded conflicting results. The objective of this study was to assess the impact of a standardized physical activity program on adiposity and cardiometabolic risk factors in schoolchildren.Methods
Cluster randomized trial study...
No resilience scale has been validated in Spanish patients with fibromyalgia. The aim of this study was to evaluate the validity and reliability of the 10-item CD-RISC in a sample of Spanish patients with fibromyalgia.
Design: Observational prospective multicenter study. Sample: Patients with diagnoses of fibromyalgia recruited from primary care se...
Objective
The relationship between cardiorespiratory fitness (CRF) and metabolic syndrome (MetS) is well known, although the extent to which body weight may act as a confounder or mediator in this relationship is uncertain. The aim of this study was examine whether the association between CRF and cardiometabolic risk factors is mediated by BMI.Rese...
Children obesity is considered a serious public health problem around the world. In Spain, the prevalence of overweight/obesity is reaching alarming figures, exceeding 35% of the children. Several hypotheses suggest that the energy balance model does not fit very well when analyzing the causes of the current obesity epidemic and, although genetics...
The quality of care in nursing homes is weakly defined, and has traditionally focused on quantify nursing homes outputs and on comparison of nursing homes' resources. Rarely the point of view of clients has been taken into account. The aim of this study was to ascertain what means "quality of care" for residents of nursing homes.
Grounded theory wa...
Objetivos
Evaluar las características psicométricas de la versión española del CD-RISC de 10 ítems en una muestra de personas mayores no institucionalizadas y examinar si mantiene la misma estructura factorial que muestra la escala original.
Método
Estudio descriptivo transversal multicéntrico de validación de una escala de medida, realizado en 5 z...
AIMS: To examine the psychometric properties of the Spanish version of the CD-RISC 10-items in a sample of the elderly population of Cuenca, Spain; and to assess if the Spanish version preserves the same factorial structure as the original one. METHODS: A cross sectional study was conducted in five health centres in the province of Cuenca. The stud...
To examine the trends in BMI and adiposity among schoolchildren from Cuenca, Spain, during 2004–2010.Two methodologically comparable surveys were carried out in 2004 and 2010.Primary schools in Cuenca, a province in the middle of Spain.All schoolchildren aged 8–11 years, belonging to 4th and 5th grades from twenty schools in the Province of Cuenca,...
To examine the trends in BMI and adiposity among schoolchildren from Cuenca, Spain, during 2004-2010.
Two methodologically comparable surveys were carried out in 2004 and 2010.
Primary schools in Cuenca, a province in the middle of Spain.
All schoolchildren aged 8-11 years, belonging to 4th and 5th grades from twenty schools in the Province of Cuen...
Background: As far as we know there are not studies that analyze jointly the relationship between obesity, cardiorespiratory fitness and muscle strength with blood pressure (BP).We aimed to determine the relationship between BMI and physical fitness with components of BP in young women. Methods: cross-sectional study in 407 women aged 18-to-30 year...
Este estudio ha sido financiado por la Fundación para la Investigación Sanitaria en Castilla-La Mancha (FISCAM) (Ref.-AN/2008/31) y el Ministerio de Sanidad y Consumo, Instituto de Salud Carlos III, Red de Investigación en Actividades Preventivas y de Promoción de Salud (Ref.-RD06/0018/0038) y por el Ministerio de Ciencia y Tecnología (RYC-2010-059...