Blanca Maria Morfin

Hospital San Angel Inn Chapulepec · Allergy

Excel file with all data pertaining to the article: Aeroallergen immunotherapy associated with reduced risk of severe COVID-19 in 1095 allergic patients

Background: Recent data about clinical features, triggers and management of anaphylaxis in Latin America is lacking. Objective: To provide updated and extended data on anaphylaxis in this region. Method: An online questionnaire was used, with 67 allergy units involved from 12 Latin-American countries and Spain. Among data recorded, demographic...

Background Few studies have explored the association between obstructive sleep apnea (OSA) and chronic urticaria (CU). Our study aims to fill this gap by determining the frequency of the risk categories for OSA and how they might correlate with the specific CU patient reported outcome measures urticaria activity score (UAS7), urticaria control test...

Introduction: Heiner syndrome is a very rare but reversible lung disease caused by non-IgE-mediated hypersensitivity to cow's milk proteins resulting in an atypical pulmonary disease in babies and infants. Very few cases have been reported. Due to its heterogeneous manifestations, the diagnosis can be delayed since it can occur with chronic or rec...

Antecedentes: El síndrome de intestino corto es el resultado de una resección quirúrgica extensa que deja la longitud del intestino delgado en un valor crítico para una adecuada absorción nutricional. Se han descrito un incremento en el riesgo de alergia alimentaria en pacientes que sufren esta condición. Objetivo: Describir la prevalencia de enfe...

Background: Allergy to cow's milk proteins is the most frequent food allergy and its prevalence has increased in the last decade. Although most patients have symptoms after the intake of dairy milk, other routes of sensitization through skin and mucous membranes have been described. Case report: A 31-year-old male patient who is a professional c...

Background: Eosinophilic esophagitis (EoE) is a chronic inflammatory disease caused by infiltration of eosinophils in the esophageal mucosa, which is frequently associated with atopy. The symptoms vary according to the age group, the most frequent being food rejection, dysphagia to solids and weight loss. Some symptoms of the upper respiratory trac...

Chronic urticaria (CU) has a widespread spectrum on causal or exacerbating factors, clinical manifestations, therapeutic response and quality of life affectation. Registries are useful tools in several real-life diagnosis and management approach.We aimed to evaluate the characteristics of CU patients living in Latin America through an original cros...

We explored in Latin America the level of usage of ICTs In Chronic Urticaria (CU as a part of UCARE Project).

Background: Updated urticaria guidelines recommend that patients should be assessed for disease activity, severity, control, and quality of life at baseline and follow up. Regarding treatment, guidelines consider second generation antihistamines as the cornerstone in therapy for chronic urticaria (CU), while other drugs, such as omalizumab, are con...

Background: Mycosis fungoides is a cutaneous T-cell lymphoma. The patch stage is limited to the skin and may spontaneously involute or progress, spreading to peripheral blood, lymph nodes and viscera. Case report: 64 year-old female with a 6-year history of dermatosis with scaly, poorly delimited and pruritic plaques on the chest and extremities...

Relation between virus infection and clinical phenotypes of drug reaction

Rapid diffusion, low cost and broad availability of information and communication technologies (ICTs) make them an attractive platform for managing care, communication and interventions in asthma. There is little information in Latin America about usage frequency of ICTs in asthmatic patients. The analysis undertaken consisted of an observational,...

Antecedentes: Se ha sugerido elevada prevalencia de enfermedades alérgicas en niños con acidosis tubular renal. Objetivos: Describir la prevalencia de enfermedades alérgicas en niños con acidosis tubular renal secundaria atendidos en el Servicio de Nefrología del Instituto Nacional de Pediatría, México. Métodos: Estudio observacional, prospectivo...

Background: It has been suggested a high prevalence of allergic disease in children with RTA. Objectives: To describe the prevalence of allergic diseases in children with secondary RTA (renal tubular acidosis) in the nephrology department of the National Institute of Pediatrics (NIP), México. Methods: An observational, prospective, cross-sectional,...

Background: Leprosy is a chronic granulomatous infection that affects skin and peripheral nerves. Its prevalence has declined, but is still observed mainly in poor rural areas. Case report: A male city dweller with photophobia and chronic dermatosis in the face: nodular and erythematous lesions, pustules, keratitis and entropion, partial eyebrow...

Background: Leprosy is a chronic granulomatous infection that affects skin and peripheral nerves. Its prevalence has declined, but is still observed mainly in poor rural areas. Case report: A male city dweller with photophobia and chronic dermatosis in the face: nodular and erythematous lesions, pustules, keratitis and entropion, partial eyebrows l...

Information regarding the clinical features and management of drug-induced anaphylaxis (DIA) in Latin America is lacking. The objective of this study was to assess implicated medications, demographics, and treatments received for DIA in Latin American patients referred to national specialty centers for evaluation. A database previously used to comp...

Background: Adverse reaction to food has increased around the world in last years. Prevalence of food allergy raises between 2-4% in adults, and 6-8% in children. The clinical presentation is heterogeneous and varies from mild symptoms to anaphylactic reactions. Even the clinical history focused in the food is important; Demonstration of allergen s...

Background Epidemiologic drug allergy data from Latin America are scarce, and there are no studies on specific procedures focusing on this topic in Latin America. Objective To assess the clinical characteristics and management of hypersensitivity drug reactions in different Latin American countries. Methods An European Network of Drug Allergy que...

Background: Asthma is a chronic airway inflammatory disease, for identification in the population epidemiological studies are required. Objective: To validate a questionnaire of asthma diagnosis in children and adults. Patients and method: A prolective, cross-sectional, homodemic and multicenter study was done in which a questionnaire of asthm...

Common ivy is an ubiquitous ornamental plant found indoors and outdoors. It may cause occupational contact dermatitis and asthma. Many traditional and naturistic preparations may contain their extracts, hence sensitization may occur by several routes. To determine the prevalence of sensitization to Hedera helix pollen by skin prick test on allergic...

Background: Cow's milk protein allergy (CMPA) is the most common food allergy in children. However, the prevalence of CMPA in disability children is unknown. Objective: To know the frequency of CMPA in disability children and to assess the clinical improvement after a suppression diet. Material and methods: We conducted a cohort study at the C...

Common ivy is an ornamental plant, that is ubiquitous in Mexico. Its allergens can cause contact dermatitis, asthma and allergic rhinitis. We describe two cases of anaphylaxis related to common ivy syrup ingestion. We performed skin prick test with Hedera helix syrup, and using a dialized and ultrafiltered of common ivy syrup commercial presentatio...

Human papillomavirus (HPV) is one of the most common sexually transmitted infections worldwide. Most HPV infections are cleared within two years by the immune system. Only in 5% to 10% of infected women the infection persists determining a high risk of developing cervical intraepithelial neoplasia. The transfer factor (TF) or dialyzable leukocyte e...

Background: Common ivy is an ubiquitous ornamental plant found indoors and outdoors. It may cause occupational contact dermatitis and asthma. Many traditional and naturistic preparations may contain their extracts, hence sensitization may occur by several routes. Objective: To determine the prevalence of sensitization to Hedera helix pollen by skin...

Background Human papillomavirus (HPV) is the most common sexually transmitted infection worldwide. About 75 to 80% of sexually active Americans will be infected with HPV at some point in their lifetime. The risk of HPV infection seems to be related with age at first intercourse, younger age and number of sexual partners. HPV infection is limited to...

Background Asthma is the most common chronic disease in children. The aim of this study was to assess the association between asthma severity and skin test reactivity to common inhalant allergens. Methods With informed parenteral consent, we included children with asthma, who attended for the first time to Allergy Department and collected data on...

Common ivy is an ornamental plant, that is ubiquitous in Mexico. Its allergens can cause contact dermatitis, asthma and allergic rhinitis. We describe two cases of anaphylaxis related to common ivy syrup ingestion. We performed skin prick test with Hedera helix syrup, and using a dialized and ultrafiltered of common ivy syrup commercial presentatio...

There are some reports on the association between the use of ipratropium bromide/salbutamol and paradoxical bronchoconstriction and urticaria in patients with soy allergy. We describe four patients who displayed angioedema and paradoxical bronchoconstriction secondary to ipratropium bromide/salbutamol administered by metereddose-inhaler (MDI). In a...

Results Median age 20 months (±12 months), 15 female (50%) 15 male(50%). IgA2 deficiency 16 (53%), IgG4 and IgA2 deficiencies 13 (43%), IgG4 deficiency 27 (90%), 29 patients had distal renal tubular acidosis (96%) 1 patient with proximal renal tubular acidosis. About food allergies, cow’s milk 28(93%), egg 18 (60%), wheat 0, corn 8 (26.6%), soy 2 (...

Objective: Some reports associate certain illnesses of the urinary system with allergies. Thus, we decided to examine the prevalence of sensitization to allergens in a group of children with primary renal tubular acidosis (RTA). Methods: Children with primary RTA who attended the nephrology department at a third level pediatric hospital during a...

To emphasize the safety and efficacy of theophylline in chronic inflammatory respiratory diseases. To mention its immunomodulatory effects. PubMed search using the keywords: theophylline, histone deacetylase, antiinflammatory, asthma, chronic obstructive pulmonary disease (COPD), corticoresistance. Theophylline is a methylxantine, that inhibits pho...

RESUMEN Objetivos: mencionar las características farmacológicas y los mecanismos de acción y efectos inmunomoduladores de la teofilina en el tratamiento de enfermedades respiratorias crónicas con componente inflamatorio. Fuente de datos: Pubmed, con base en estas palabras: teofilina, histona desacetilasa, antiinflamatorio, asma y enfermedad pulmona...

Several studies suggest that the prevalence of allergic diseases has been increasing worldwide in recent years; then it is very important to identify some risk factors that could be related. To know some hereditary and environmental risk factors that could be related to the development of allergic diseases in open population from Mexico City. It wa...

In Mexico City, where the Olive trees are scarce, the Oleaceae family has been recognized as one of the most important causes of pollen allergy, possibly related to cross-reactivity with other pollens of the Oleaceae family, as Fraxinus excelsior, Ligustrum vulgaris and Osmanthus americanus. To know the prevalence of sensitization to the Oleaceae f...

RESUMEN Las células cebadas tienen funciones efectoras tanto en la respuesta inmune innata, como en la adaptativa, promoviendo la inflamación alérgica, remodelación tisular y el daño a los tejidos principalmente debido a su activación sostenida. Sin embargo, los mastocitos también tienen efectos antiinflamatorios e inmunosupresores. De hecho, la cé...

It has been described two main phenotypes of helper T cells. On activation, the immune system develops the most effective Th response. Whereas Th1 cells promote cell-mediate immunity against intracellular pathogens and an over expression could favor autoimmune diseases; Th2 cells develop humoral immunity against extracellular pathogens promoting al...

It has been described two main phenotypes of helper T cells. On activation, the immune system develops the most effective Th response. Whereas Th1 cells promote cell-mediate immunity against intracellular pathogens and an over expression could favor autoimmune diseases; Th2 cells develop humoral immunity against extracellular pathogens promoting al...

Viral infections can promote allergic sensitization in genetically susceptible individuals. Besides, they are the main cause of wheezing in children. To assess the frequency with which influenza, parainfluenza, adenovirus and respiratory syncytial virus (RSV) cause rhinopharyngitis in patients with asthma and wheezing. Longitudinal, prospective stu...

Natural rubber latex has been in widespread use for over a century. Reports of immediate hypersensitivity to latex have increased dramatically since the first case was reported in 1979, specially in persons with cumulative latex exposure. A 13 year old male was referred to our office. He had been wearing orthodontic rubber bands for two years. The...

Many reports have found an association between allergy and kidney and urinary tract disorders. Considering the fact that both kidneys and the urinary tract help to clear waste substances from the body by way of a process of filtration, collection and excretion, an in situ sensitization of the kidney and urinary tract to the macromolecules contained...

RESUMEN El látex natural se ha utilizado desde hace más de 100 años. A partir del primer reporte documentado de alergia al látex, en 1979, se describieron múltiples casos especialmente en personas con exposición continua. Se comunica el caso de un varón de 13 años de edad enviado a nuestra especialidad por posible alergia al látex. Durante dos años...

Olea europaea (olive) which is original from Europe, was introduced to Mexico by the Spaniards in the 16th century. In 1777 olive farming was prohibited, and plantations were destroyed. At present there are only few trees in Southern Mexico City. The aim of this study is to investigate sensitization to Olea europaea, clinical features, IgE levels,...

The study aimed to evaluate the household smoking habits as risk factors for wheezing in adolescents. During a 2-month period, the study was performed by applying the standardized ISAAC phase 1 questionnaire to 3474 adolescents attending a random sample of secondary public schools located at the southeast of Mexico City. Adolescents were grouped as...

There is some evidence suggesting a link between paracetamol exposure and atopy in both adults and children. We aimed to investigate whether further epidemiological support for a link between paracetamol intake and allergy could be found in a population of Mexican children. In a cross-sectional study design, we applied the ISAAC questionnaire to 34...

Papular urticaria is a cutaneous manifestation caused by the sensitization to salivary antigens inoculated in insect bites. It is mainly seen in children. Clinical, aetiological, epidemiological, histophatological and immunological features are considered, as well as prevention and treatment aspects.

Lepisma saccharina is an ubiquitous insect that mainly lives in bedroom and family room. Even when due to its high tropomyosin content it is able to produce crossed allergic reactions with other insects, its allergenic fractions have not been completely characterized and an allergenic extract with diagnostic purposes has not been developed, so its...

A 65-year old woman suffered from therapy resistant chronic blepharoconjunctivitis and rosacea, without improvement under therapy of systemic and topic antibiotics and topic steroids and antihistamines. Demodex folliculorum was found adhered to the hair bulb on microscopic examination. She received oral ivermectin with good response. Two months lat...

Polyarteritis nodosa is a diffuse vasculitis of small- and medium-sized muscular arteries that can involve the vessels of one or several organ systems. We report an 11-year-old boy with severe atopic dermatitis further complicated with erythroderma and cerebellar symptoms. Laboratory studies showed negative antinuclear antibodies and antineutrophil...

This paper describes a 36 year-old white woman with six month history of epigastric abdominal pain, reactive arthritis and painful dermographism. Serum antibodies to Helicobacter pylori were identified. All symptoms subsided when she received eradication treatment.

Some clinical reports suggest that allergic and reno-urinary diseases could be associated. Etiopathogenic aspects are described, as well as some clues of anamnesis that will help us to suspect allergic etiology.

The aim of this study was to made a correlation between allergic symptoms, positive skin prick test to fungi, total and specific IgE and mold culture in the patient's environmental. There were included 35 children (3-16 years), with skin prick test positive to fungi. The most frequent were: Rhizopus, Aspergillus, Cladosporium and Candida. Total and...

Background: Atopic dermatitis (AD) is an important cause of pediatric morbidity. Its prevalence in Mexican children is not known. The objective of this paper is to determine the prevalence of AD among a group of Mexican children; the possible influence of hereditary and environmental risk factors in the development of the disease; the frequency wit...

There is a considerable variation in the prevalence of allergic disorders in developing countries. These differences may be attributable to different methodological problems and to the lack of operational definitions. Several studies suggest that the prevalence of allergic diseases has been increasing worldwide in recent years. However, in Mexico,...

Otitis media is an inflammation of the middle ear, and a common problem of childhood. Acute otitis media and its different outcome; the factors implicated in the pathogenesis and in persistent infection; and the incriminated agents, sequels and complications are described. Conservative and surgical approaches are mentioned. Control of predisposing...

The role of viral infections as a part of the environmental factors that triggered asthma in atopic subjects, their age specific pattern, as well as many risk factors for the development of subsequent wheezing are described. Some pathogenic mechanisms and their importance in the induction of airway inflammation are mentioned and early identificatio...

Artículo original Revista Alergia México 2007;54(5):156-61 RESUMEN Antecedentes: Olea europaea (olivo) se introdujo a México por los españoles en tiempos de la colonia. En 1777 se prohibió su cultivo y los plantíos fueron destruidos. Actualmente existen pocos árboles al sur de la Ciudad de México. Objetivo: determinar la prevalencia de sensibilizac...