Biswajyoti Patgiri

Biswajyoti Patgiri
Gujarat Ayurved University · Dept of RS&BK

MD(Ayu.), PhD

About

63
Publications
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308
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December 1999 - July 2016
Gujarat Ayurved University
Position
  • Professor&Head

Publications

Publications (63)
Article
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Amrutikarana is a process explained in Ayurveda classics to remove any remaining blemishes from Bhasma preparations and improve their efficacy. It is mainly indicated in the context of Abhraka, Lauha and Tamra Bhasma. Abhraka Bhasma is one of the most widely used Bhasma preparations in Ayurveda with the most diverse methods and number of Puta. Aim...
Article
Background: Bakuchi (Psoralea corylifolia Linn.) has immense therapeutic attributes and widely prescribed drug in skin disorders especially Shvitra (vitiligo). Its medicinal usage is found depict in Indian pharmaceutical codex, the Chinese, British and the American pharmacopoeias and in different traditional system of medicines such as Ayurveda, Un...
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INTRODUCTION: Haratala is Uprasa mentioned since vedic period. Chemically, it is Arsenic trisulfide and also classified under schedule E1 drug. There are methods and medias used for Shodhana of Haratala. In the present study for Shodhana of Haratala, three Shodhana media have been taken, i.e., Triphala Kwatha, Tila Tail, Kanji. AIM: The aim of the...
Article
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Objectives: Ayurvedic metallic preparations are always a concern for the safety issue. A special process was also designed in the ancient classics of Rasashastra to remove the blemishes of such metallic preparation known as Amrutikarana. Different materials and methods are elucidated for this purpose which modifies the efficacy and glance of the in...
Article
Introduction: Sameera Pannaga Rasa (SPR) is a Kupi Pakwa Rasayana (a mercurial-arsenical formulation of Ayurveda prepared by specific pharmaceutical-controlled, indirect heat treatment [sand bath] in glass bottle) that contains Shodhita Parada (processed mercury), Shodhita Gandhaka (processed sulfur), Shodhita Haratala (processed arsenic trisulfid...
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Background: Shelf life is the length of time, after which all substances starts to degrade in their qualities and become unsuitable for consumption or sale. Every product has definite shelf life, which depends on various physical, chemical, environmental, and biological factors. Shelf life of various compound formulations was clarified in the class...
Article
A pharmaceutical manufacturing process involves many variables that affect the product quality viz. sensory variables, process variables as well as human factors. Humans are involved at each and every step of the process and play a significant role in improving the product quality. One way to control human factors is training. In the present study,...
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Background: Steroidal and non-steroidal anti-inflammatory agents have several limitations, due to which people are moving towards use of traditional medicines. Considering this, the current attempt is aimed to evaluate in vivo anti-inflammatory effect of a poly-herbal formulation Śirīṣāvaleha prepared in presence of water and Kanji (sour gruel). Ka...
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Background: Pancreatic ductal adenocarcinoma is the fourth leading cause of cancer-related mortality. Efforts to improve cancer treatment through nanotechnology are at the developmental stage, and it will be gracious if the drug with anticancer property itself is a nanoparticle. Bhasma is organomineral complexes which are bioactive nanoparticles....
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CONTEXT: The different dosage forms of Ayurveda are mostly prepared in the presence of Jala (water) as Drava dravya (extracting medium). Transfer of the medicinal properties of any Dravya (drug) is done on the virtue of Drava dravya (liquid medium). Screening through the classics reveal that seers used Drava such as Kshira (cow's milk), Gomutra (co...
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Introduction: Avaleha (Linctus) is a unique dosage form of Ayurveda that is frequently used in various disorders and as Rasāyana (Immunomodulators). Aṣṭāngavaleha is one such formulation being used for Śvāsa (Asthma), Jvara (Fever), Hikkā (Hiccup) and Kāsa (Cough). Aṣṭāngavaleha has not been mentioned in Brūhattrayī. It had been extensively reviewe...
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Bhasma are one of the Unique preparation used in Ayurveda and has been used as effective drugs from centuries. It have various Vernicular names sisa, sisu, sisamu, usrup, plumbum, lead The synonms are Sisa, Kutila, Ahí, Pannaga, phani, kari, urga, Bhujana, kuvanga, paripishta. Naga is very useful in treating Diabetes mellitus, Rheumatoid arthritis,...
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Context: Control of cough remains a major unmet medical need. There is a need to have safe and effective anti‑tussive drug that can alleviate chronic cough without developing side effects. Ashtangavaleha is an effective compound formulation for combating the disease asthma. Aim: The present study was carried out to evaluate anti‑tussive activity of...
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Introduction-Nishamalaki [combination formulation of Turmeric and Indian goose berry (Emblica officinalis Gaertn.)]; is recommended in Ayurvedic classics, proven efficacious and widely practiced in the management (treatment, prevention of complications) of Madhumeha (Diabetes Mellitus). Dose related antihyperglycemic activity of Nishamalaki prepare...
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Turmeric (Haridra) is one of the versatile herb for spices, condiment and anti-diabetic activity in Indian System of medicine and tropical country. To compare the in-vitro enzymatic inhibitory effect (α-amylase and α-glycosidase) for supporting purified (shodhita) and raw turmeric samples. Authenticate unprocessed and processed (ayurvedic classic)...
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Introduction: Avaleha (linctus) is the secondary dosage form which is widely acceptable and palatable in Ayurvedic system of medicine. In classics, most of the Avaleha are either prepared with sweetening agent like jaggery, sugar or mentioned in the powder form; and are advised to be licked with honey etc. Ashtangavaleha is a herbal formulation men...
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Introduction: Rasa Śāstra is a branch of science exclusively dealing with different aspects of metals and minerals including their origin, varieties, characteristics, processing techniques, properties, therapeutic applications etc. in a comprehensive way. These metals and minerals are to be processed before their internal administration. The proces...
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Introduction: Kuṅkumādi Ghṛta (KG) is an Ayurvedic formulation commonly recommended in skin disorders, especially Mukhadūṣikā (Acne vulgaris). Kesara (stigma of Crocus sativus Linn.) is a prime ingredient in the formulation. However, due to high cost and increased adulteration in Kesara, 'Nāgakesara' (Mesua ferrea Linn.) is suggested by Ayurvedic...
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Introduction: Gandhaka Jarana is intermediate procedure for the therapeutic mercurial preparations in Ayurveda Rasashastra. For Gandhaka Jarana numerous procedures were mentioned in the classical texts of Rasashastra. Here, Shadguna Balijarita Makaradhwaja prepared in classical Valuka Yantra by adopting one of the method of Gandhaka Jarana. Objecti...
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Background and objectives: A huge number of drugs have been emphasized in Ayurveda like Makaradhwaja (mercurial preparation), Guduchi Ghana (dried extract of Tinospora cordifolia Linn) etc. in the treatment of Madhumeha (Diabetes mellitus). Nevertheless, their efficacy was not reported till date. Considering this, it is attempted to evaluate its ef...
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Abstract Background: Swarna Bhasma (incinerated gold) is used as a therapeutic medicine from long ago in the Ayurvedic medicinal practice. The numbers of procedures for its preparation were mentioned in the texts of Rasashastra. Bhasma is prepared from the different metals and minerals by its systemic incineration with specific herbals and other re...
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Abstract: Makaradhwaja is a popular medicine of Ayurveda used for vigor and vitality. It is mentioned in classical texts of Rasashastra that Makaradhwaja increases longitivity of life and contest aging process. It is used internally for wide range of disorders like Jwara (fever), Prameha (diabetes mellitus), Agnimandya (loss of appetite) etc. Makar...
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Introduction: Kamsaharitaki Avaleha is a well-known ayurvedic preparation. Considering certain inconveniences of Avaleha, an attempt has been made to convert it into granules that are convenient in handling, dispensing, and storage. Aim: To convert Kamsaharitaki Avaleha into granules form and develop standard manufacturing procedure. Materials...
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Abstarct Swarna Bhasma (SB) (incinerated gold) is one of the most potent and popular medicine among all Ayurvedic Medicines. Several procedures of its preparation are mentioned in the classical texts of Rasashastra. In the present study Swarna Bhasma is prepared and anlysed to develop its standard parameters. Three batches of SB were prepared and a...
Article
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Introduction: Bronchial asthma is one of the chronic inflammatory disorders of the respiratory tract causing a huge number of deaths annually. Increased industrialization and pollution are the exacerbating factors for this situation. In Ayurveda, this miserable condition is comparable with Tamaka Shwasa. Synthetic drugs provide instant symptomatic...
Article
Introduction: Laghu Malini Vasanta (LMV) Rasa is a well-known Vasanta Kalpa (formulation). As per reference of Yoga Ratnakara, Rasaka and Maricha are chief ingredients in 2:1 proportion. Bhavana (levigation) is said to be given first with Navaneeta (freshly prepared cow's butter) and then with Nimbu Swarasa (lemon juice) until Ghrita Vimukta stage...
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Background: Guduchi Ghana is one of the unique Ayuvedic classical preparation which is prepared from aqueous of extract of Guduchi (Tinospora cordifolia Miers.) stem. It is one of the frequently used drugs to treat the Madhumeha, Pandu, Kamala, Amlapitta, Grahani, Kustha, Jirna Jwara and Viswamjwara, Trishna, Shool, Yakritavikara, etc. Looking to t...
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Background: Standardization of Ayurvedic medicine is the need of hour to obtain desired quality of final product. Shodhana literally means purification, is the initial step to make drugs like metals, minerals and poisonous herbs suitable for further procedure. Shodhana of metals/minerals help to expose maximum surface area of drug for chemical rea...
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Introduction: Tamra Bhasma (TB) and its forms like Somnathi Tamra Bhasma (STB), etc., are in vogue since centuries in Ayurveda. The present study is carried out to evaluate the effect of TB and STB in different dose levels on ponderal and biochemical parameters in wistar strain albino rats to provide scientific basis for its safety profile. Materi...
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Ayurvedic system of medicine has stood the test of time for four millennia or more. Ancient seers found that the drugs from different origin (herbal, metal or animal) are the most suitable tools in maintaining health in the healthy and eradicating diseases in the diseased. The use of metallo-mineral preparations in healthcare is a unique characteri...
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Context: Amrita (Tinospora cordifolia Willd.) an often used perennial climber used in different clinical conditions and various researches are useful in understanding its potential, but comparative pharmacognostical study of stem, true root and aerial root is not available till date. Root of Amrita is often used in folklore medicine. As true root i...
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Concept of Saviryta Avadhi (shelf-life) of Ayurvedic dosage forms is well-defined in classics of Ayurveda. Information on this is scattered in initial classics of Ayurveda like Charaka Samhita, but focused well after 13(th) Century AD in texts such as Vangasena Samhita, Sharangadhara Samhita and Yogaratnakara. Though the concepts have a strong back...
Article
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Rasasindura (RS) sublimated mercurial preparation often used in diseases like Madhumeha (Diabetus mellitus), Rajayaksma (Tuberculosis), Pandu (Anaemia), Sthoulya (Obesity), Mandagni (Impaired digestive fire) etc. Mercurial preparations are constantly targeted due to lack of documentation and published works. Till date several research works have be...
Article
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India has long tradition of using Ayurvedic medicines as therapeutic agent. In comparison to rapid growth of herbal market, export rate of traditional Indian medicine is quite insignificant. It might be due to lack of proper quality control measures of raw materials and formulation. So, it is essential to ensure quality, safety and efficacy of raw...
Article
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The aim of the study was to find out the immunomodulatory effect on humoral anti-body formation of Vyaghriharitaki avaleha (VHA). Standard procedure of Doherty (1981) was followed. Wister strain albino rats of either sex weighing between 160-240 g were selected and divided into 3 groups. First group received tap water serving as the normal control....
Article
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Introduction: Rasasindura (RS) is a sublimated mercurial preparation known for its use in different formulations. The efficacy of RS will enhance with the quantity of sulphur and duration of heating, hence Shadguna Rasa Sindura (SRS) (1:6 proportion of Hg:S) is said to be superior. Objective: Present study attempts to standardize mode of preparatio...
Article
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Introduction: Shodhana (purification) of metals and minerals is a most important step before preparing their bhasma (incinerated powder). Shodhana treatment removes the soluble, evaporable and washable impurities from metal/mineral and also adds some organic materials which from chemical point of view may be considered as impurities but pharmacolog...
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The metal, Tamra though mentioned in Ayurveda with a wide range of therapeutic utilities; is attributed with Ashta Maha Dosha. Hence, one should be cautious while using Tamra Bhasma. Considering the significance of Tamra in therapeutics, many studies have been carried out at different centers of India. Aim of the present study was to compile such a...
Article
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Rajata bhasma (incinerated silver) potentially utilized in various formulations such as Jayamangala Rasa, Mahamraganka Rasa, Lakshmivilasa Rasa, Vatagajankusha Rasa, Vijaya Parpati etc. Silver being a noble metal is said to be superior among metals after Gold. Works emphasizing on pharmaceutical standardization of Rajata Bhasma (RB) are very few. T...
Article
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Standardization is necessary to ensure quality and purity of the herbal drugs. It is equally important to establish system of standardization for every plant used in the herbal formulation to develop safe and quality based herbal formulation. Present study is initiated with to establish a standard methods and quality parameters for Rasayana Churna....
Article
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Tamra Bhasma (incinerated copper) is one of the main weapons in the archery of Ayurvedic practitioners. Though several methods of preparation of Tamra Bhasma (TB) are found in Rasashastra classics, several difficulties occur during the preparation of a good-quality Bhasma. In this study, TB was prepared and analyzed to develop the standard manufact...
Article
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Makaradhwaja is a herbo-minaral drug prepared by Kupipakwa method. In the present study Makaradhwaja was prepared by Triguna and Shadguna Balijarana using Ashtasamskarita Parada. Total five batches of Triguna Makaradhwaja (TM) were prepared by taking 330 g of Kajjali in each batch, average product obtained was 29.12 g. In the preparation of Shadgun...
Article
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Extremely diminutive published information is available on the mutagenic activity of Ayurvedic Bhasmas. Genotoxicity of few Bhasmas were reported on single maximum dose, but no reference is available on the sub-chronic level. Hence the present study was carried to generate and evaluate genotoxic potentials of Swarna Makshika Bhasma (mineral prepara...
Article
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Incidences of Bronchial Asthma have been raised in recent decades due to increased industrialization and pollution. This miserable condition can be compared with Tamaka Shwasa in Ayurveda. Modern synthetic drugs will provide instant relief in these cases, but are tend to develop a number of adverse drug reactions. Knowing this, the current sufferin...
Article
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Mamajjaka (Enicostemma littorale Auct. non Bl) is a well known folklore medicine frequently used for the treatment of Madhumeha (diabetes mellitus). There is no direct reference available for its antihyperglycaemic activity in Ayurvedic classics. Considering this, a study is planned towards developing pharmaceutical standardization of Mamajjaka Gha...
Article
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Metallic Bhasmas are highly valued and have their own importance in Ayurvedic formulations. To testify the Bhasmas various parameters have been told in Rasashastra classics. Tamra Bhasma (TB) with its different properties is used in the treatment of various diseases is quiet famous among the Ayurvedic physicians (Vaidyas). The present study was car...
Article
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Rasasindura (RS) is one of the unique mercurial preparations commonly used in Ayurveda therapeutics. The traditional procedure followed for preparing RS in the classical furnace has several drawbacks, such as difficulty in controlling temperature, consumption of large quantity of fuel, and excess human effort. AIMS #ENTITYSTARTX00026; The present s...
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Epidemological data reveals that, in the present era of industrialization, the incidence and prevalence of Tamaka Shwasa (bronchial asthma) is largely growing, imposing and increasingly large burden to health services. An Ayurvedic formulation, Vyaghrihareetaki avaleha (VHA) is a potent drug indicated for shwasa (Asthma), kasa (cough) etc and used...
Article
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Herbs are staging a come-back and the herbal renaissance is “the happening” all over the globe. Ironical fact – Ayurvedic System of medicine is still struggling to reach the heights beyond numerous hurdles in its path. One such hurdle is controversy over botanical identity of drugs. Among the many drugs under controversy the drug nagakeshara is als...