Bircan Dinç

• Doctor of Biophysics
• Dr. at Bahçeşehir University

Regeneration of the dentin-pulp complex remains a challenge in endodontics due to the limited capacity of conventional treatments to restore full biological function. Stem cell-based strategies using biocompatible scaffolds have been explored as alternative approaches, particularly with stem cells from human exfoliated deciduous teeth (SHED), which...

The regeneration of bone tissues using a composite-based tissue engineering approach is a promising strategy for repairing and restoring their biological functions. This study extensively investi gates the development and potential applications of Multi-Walled Carbon Nanotube-Polylactic Acid (MWCNT-PLA) composites for bone defect healing. The s...

Optogenetics, a revolutionary technique leveraging light stimulation for precise cellular control, holds immense potential in regenerative medicine. Offering unparalleled spatial and temporal accuracy, the entrance of optogenetics into tissue engineering and regenerative medicine (TERM) empowers researchers to modify genes precisely and reversibly,...

The degree of monomer conversion (DC) values of three different dental composites were examined using three different methods: surface microhardness (ratio of bottom/top), Fourier-transform infrared (FT-IR), and differential scanning calorimetry (DSC). Two of the dental composites included in the study were nanohybrid (Dentsply Neo Spectra ST HV an...

Herkese Bilim ve Teknoloji Dergisinin 403. Sayısında, nano parçacıkların çevreye verebileceği potansiyel zararlara ve bu özel malzemeler için, belirli bir atık prosedürünün olmaması konusuna değindim.

Regenerating dentin-pulp complex (DPC) using tissue engineering offers a novel and promising therapeutic alternative for restoring teeth. A crucial component of such a therapy is the designing and fabrication of an appropriate 3D Scaffold. In this review, we set out to highlight some of the general challenges associated with optimizing the most sui...

AFs are among the most dangerous compounds, exhibiting carcinogenic effects on human and liver tissue. Due to their high toxicity and established limits in food and feed products, there is a growing demand for more accurate and sensitive detection methods. Detecting AFs is of paramount importance for ensuring food safety, as even low concentrations...

Molecular Dynamics

The Differential Scanning Calorimeter (DSC) technique is commonly used for quantitative analysis of protein stability, and it is one of the methods used to quantify protein-ligand interactions. DSC provides denaturation curves that can be a source of data on binding constants. B-cell leukemia/lymphoma-2 (BCL-2) is an antiapoptotic protein, one of t...

Silica nanoparticles (SiNPs) demonstrate exceptional properties that vary depending on their intended applications. It is imperative to comprehend the toxic effects associated with these nanoparticles, which have gained wider use due to diverse synthesis methods and application areas. The sol-gel method yields SiNPs with a radius ranging from 4 to...

Rapid and easy detection of pathogens, especially bacteria, plays an important role in daily life in the face of increasing environmental pollution. Nanosensors focus on carbon nanotubes, which can bind various molecules to large surfaces and have high electron conductivity. They are widely used in the development of electrochemical biosensors. In...

Lipid-based drug delivery systems are promising systems for hydrophobic drug delivery. A lipid-based self-nano-emulsified ocular drug release system has been synthesized for improving the topical ocular delivery of hydrophobic drugs. The aim is to develop preformulation that reaches the vitreal fluid, bypassing the ocular barriers, without requirin...

5 Milk proteins occupy a prominent place in the nutrition of adults and children. Generally, milk 6 is a mixture containing proteins, lactose, other sugar derivatives, and as well as additives in some 7 commercial milk. In commercial milk, the proportions of the components that make up the milk are 8 different. For this reason, analyzing milk corre...

Milk proteins occupy a prominent place in the nutrition of adults and children. Generally, some commercial dairy contains proteins, lactose, other sugar derivatives, and additives. The proportions of the components that make up the milk are different in commercial milk. For this reason, analyzing milk correctly is essential for determining these co...

Multi-Walled Carbon Nanotubes (MWNTs) investigated before and after acid functionalization. Here, the comparative analysis of MWNTs with different bulk densities reveals similar Raman and FTIR spectra before and after acid functionalization except for minor differences. However thermal analyses show some basic differences for both MWNTs before and...

Tea and coffee are the most popular beverage and there is a variety of forms in both hot and cold temperatures. Black tea is made from green tea leaves that have been oxidized. During the oxidation process, a certain proportion of polyphenol compounds is lost. Coffee is a complex beverage containing more than a thousand chemical compounds. Caffeine...

Tıbbi malzeme, ilaç ve aşılar, insanların kullanımına sunmadan önce deney hayvanları üze-rinde test edilmekte-dir. Bu testlerde kul-lanılan tüm hayvanla-rın kayıtlı, yasal deney hayvanı üreticisi ve tedarikçilerinden alınması gerekir. Belirli şartlar altında, veteriner hekim uy-gun görmüşse bu hayvanlar tekrar denek olarak kullanıla-bilmektedir. Ha...

SPICES, THEIR USAGE in MEDICAL APPLICATIONS, AND THEIR ANALYSIS with DIFFERENTIAL SCANNING CALORIMETRY

SYNTHESIS, FUNCTIONALIZATION, AND USE of CARBON NANOTUBES in FILTERS AND BIOSENSORS

Objective: Multi-walled carbon nanotubes (MWNTs) are obtained by rolling up the graphene structure to form multi-walled cylindrical structures, find wide usage areas in different areas with their large surface areas, hydrophobicity, and high electron conductivity. Evaluation of antibacterial effects has become very important in recent years. In thi...

The flavor and many beneficial properties of coffee make it the most consumed beverage in the world. Coffee is a complex beverage containing more than a thousand chemical compounds, including carbohydrates, lipids, nitrogenous compounds, vitamins, minerals, alkaloids and phenolic compounds. Caffeine content is one of the important issues that are e...

Amaç Bu çalışmada, Favipiravir ve Montelukast'ın diferansiyel taramalı kalorimetre (DSC) ve Fourier dönüşümlü kızılötesi spektroskopisi (FTIR) ile karakterizasyonu yapılarak, A549 (insan akciğer kanseri) hücrelerinde canlılık değerlerinin incelenmesi hedeflenmiştir. Gereç ve Yöntemler İlaçlar FTIR ölçümlerinde 3 mg, DSC ölçümlerinde 10 mg olarak ku...

Amaç Bu çalışmada, Aquilaria agallocha (Thymelaeaceae) odun kısımlarından elde edilen bitkisel yağın 7 farklı konsantrasyonu (% 2, 4, 6, 8, 10, 16 ve 24) hazırlanmıştır. Elde edilen bitkisel yağın akciğer kanseri hücre hattı A549 üzerine etkilerinin araştırılması amaçlanmıştır. Gereç ve Yöntemler Diferansiyel Taramalı Kalorimetre Cihazı (DSC), Yüks...

Neuroscience tries to understand the structure and functions of the human brain, which is made up of millions of neurons and billions of synapses. It is not possible to create and examine a model for such an advanced system in a laboratory environment. For more than two decades, Caernohabditis elegans (C. elegans) has come to the fore as a useful m...

Carbon nanotubes have become widely used due to their superior physiochemical properties, and so knowledge of their toxicity has become important. In this study, the toxic effects of nanotubes on Caenorhabditis elegans have been investigated. Multi-walled carbon nanotubes were characterized by transmission electron microscopy and particle size anal...

Carbon nanotubes (CNT) have high surface area and absorption capabilities and the absorption capacity of multi-walled CNTs (MWNTs) enables paramagnetic nanotubes to be obtained by absorbing iron salts. Characterization of paramagnetic MWNTs was performed with TEM, FTIR, DSC, and VSM. Paramagnetic CNTs are used for the purification of water from hea...

The use of 5 GHz Wi-Fi has spread and potential effects on microorganisms and human health are still under investigation. To investigate the possible effects for that, experiments were performed using three different microorganisms, Escherichia coli, SH-SY5Y human neuroblastoma cells and Caernohabditis elegans. The maximum allowed temperature for t...

Poly ADP-ribose polymerases (PARPs) are family of proteins that use nicotinamide adenine dinucleotide (NAD) as substrate. Seventeen putative PARP sequences were determined in the human genome. Although PARPs show a variety of functions and low sequence identities, they share common structural and functional properties. In our study, PARP1 and PARP2...

Multi-walled carbon nanotubes (MWNTs) are suitable for delivering large biomolecules with lower cytotoxicity values and low prime cost. Surface modifications of MWNTs affect interaction with cells and proteins. Oxidation with strong acids decreases cytotoxicity of CNTs and increases protein-loading capacity. Here, after oxidation, TEM images reveal...

Carbon nanotube (CNTs) is a new alternative for efficient drug delivery and it has a great potential to change drug delivery system profile in pharmaceutical industry. One of the important advantage of CNTs is their needle-like, cylindrical shape. This shape provides a high surface area for multiple connections and adsorption onto for millions of t...

The application of lasers and other optical technology to problems in biomedicine is a rapidly growing field. These applications can be classified as either therapeutic or diagnostic. In therapeutic applications, the transformation of light energy into chemical, thermal or mechanical energy, via light absorption, can cause a direct and selective ce...