Bindu Kalesan

Bindu Kalesan
Boston University | BU · Department of Medicine

PhD, MPH

About

141
Publications
15,513
Reads
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8,687
Citations
Additional affiliations
September 2015 - present
Boston University
Position
  • Director of Evan's Center for Clinical Translational Epidemiology and CER
September 2014 - present
Columbia University
Position
  • Research Assistant
September 2014 - present
Gun Violence Survivors Foundation, United States
Position
  • Vice President
Description
  • http://gvsfoundation.org/

Publications

Publications (141)
Article
Background: Transcatheter aortic valve replacement (TAVR) offers a new treatment option for patients with aortic stenosis, but costs may play a decisive role in decision making. Current studies are evaluating TAVR in an intermediate-risk population. We assessed the in-hospital and 1-year follow-up costs of patients undergoing TAVR and surgical aor...
Article
This study sought to assess stent strut coverage, malapposition, protrusion, and coronary evaginations as markers of healing 5 years after implantation of sirolimus-eluting stents (SES) and paclitaxel-eluting stents (PES), by optical coherence tomography (OCT). Early-generation drug-eluting stents have been shown to delay vascular healing. A total...
Article
Full-text available
The preferred initial treatment for patients with stable coronary artery disease is the best available medical therapy. We hypothesized that in patients with functionally significant stenoses, as determined by measurement of fractional flow reserve (FFR), percutaneous coronary intervention (PCI) plus the best available medical therapy would be supe...
Article
Full-text available
The efficacy and safety of drug-eluting stents compared with bare-metal stents remains controversial in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). To compare stents eluting biolimus from a biodegradable polymer with bare-metal stents in primary PCI. A prospective, ra...
Article
Full-text available
Introduction Rheumatic heart disease (RHD) remains a major contributor to morbidity and mortality in developing countries. The reported prevalence rates of RHD are highly variable and mainly attributable to differences in the sensitivity of either clinical screening to detect advanced heart disease or echocardiographic evaluation where disease is d...
Article
This study evaluated Multidimensional Geriatric Assessment (MGA) as predictor of mortality and major adverse cardiovascular and cerebral events (MACCE) after transcatheter aortic valve implantation (TAVI). Currently used global risk scores do not reliably estimate mortality and MACCE in these patients. This prospective cohort comprised 100 consecut...
Article
Full-text available
Early generation drug-eluting stents (DESs) reduce restenosis and repeat revascularization procedures. However, the long-term safety and efficacy of early generation DES according to diabetic status are poorly established. A total of 1,012 patients were randomly assigned to treatment with sirolimus-eluting (n = 503) or paclitaxel-eluting stents (n...
Article
Anemia is frequent among patients with cardiovascular disease and adversely affects prognosis. The objective of this analysis was to assess the impact of anemia on long-term clinical outcomes among patients undergoing percutaneous coronary intervention (PCI) with the unrestricted use of drug-eluting stents (DES). Between April 2002 to March 2009, 6...
Article
Early-generation drug-eluting stents releasing sirolimus (SES) or paclitaxel (PES) are associated with increased risk of very late stent thrombosis occurring >1 year after stent implantation. It is unknown whether the risk of very late stent thrombosis persists with newer-generation everolimus-eluting stents (EES). We assessed the risk of stent thr...
Article
Objectives: The goal of this study was to investigate sex-based differences in long-term clinical and angiographic outcomes after coronary revascularization with drug-eluting stents (DES). Background: The impact of sex on clinical and angiographic outcomes following revascularization with DES is not well established. Methods: Individual patien...
Article
Full-text available
To evaluate safety and effectiveness of early generation drug-eluting stents (DES) compared with bare-metal stents (BMS) in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI), and to determine whether benefits and risks vary over time. We performed a meta-analysis of 15 rando...
Article
Patients with ischemic stroke or transient ischemic attack presumably related to patent foramen ovale (PFO) are at risk for recurrent cerebrovascular events. Differences in long-term clinical outcome were investigated among patients with percutaneous PFO closure and those who received medical treatment. Between 1994 and 2000, 308 consecutive patien...
Article
The goal of this study was to compare the long-term clinical outcome between everolimus-eluting stent (EES) and sirolimus-eluting stent (SES) in patients with acute coronary syndromes (ACS). EES have not been directly compared with SES in ACS patients to date. Between 2004 and 2009, 1,746 consecutive ACS patients (ST-segment elevation ACS [STE-ACS]...
Article
Full-text available
Late acquired incomplete stent apposition (ISA) is more common after drug-eluting stent (DES) than bare metal stent (BMS) implantation and has been associated with vascular hypersensitivity and stent thrombosis (ST). We investigated the impact of incidentally discovered ISA as assessed by intravascular ultrasound (IVUS) 8 months after DES implantat...
Article
The aim of this study was to assess the role of transcatheter aortic valve implantation (TAVI) compared with medical treatment (MT) and surgical aortic valve replacement (SAVR) in patients with severe aortic stenosis (AS) at increased surgical risk. Elderly patients with comorbidities are at considerable risk for SAVR. Since July 2007, 442 patients...
Article
The effectiveness of durable polymer drug-eluting stents comes at the expense of delayed arterial healing and subsequent late adverse events such as stent thrombosis (ST). We report the 4 year follow-up of an assessment of biodegradable polymer-based drug-eluting stents, which aim to improve safety by avoiding the persistent inflammatory stimulus o...
Article
Full-text available
Examine the longitudinal effects of personal narratives about mammography and breast cancer compared with a traditional informational approach. African American women (n = 489) ages 40 and older were recruited from low-income neighborhoods in St. Louis, Missouri, and randomized to watch a narrative video comprised of stories from African American b...
Article
This study sought to investigate safety and efficacy of biolimus-eluting stents (BES) with biodegradable polymer as compared with sirolimus-eluting stents (SES) with durable polymer through 2 years of follow-up. BES with a biodegradable polymer provide similar efficacy and safety as SES with a durable polymer at 9 months. Clinical outcomes beyond t...
Article
Long-term comparative data of first-generation drug-eluting stents are scarce. We investigated clinical and angiographic outcomes of sirolimus-eluting (SES) and paclitaxel-eluting stents (PES) at 5 years as part of the Sirolimus-Eluting Versus Paclitaxel-Eluting Stents for Coronary Revascularization (SIRTAX) LATE study. A total of 1012 patients wer...
Article
Transcatheter aortic valve implantation (TAVI) is a treatment option for high-risk patients with severe aortic stenosis. Previous reports focused on a single device or access site, whereas little is known of the combined use of different devices and access sites as selected by the heart team. The purpose of this study is to investigate clinical out...
Article
This study sought to compare the unrestricted use of everolimus-eluting stents (EES) with sirolimus-eluting stents (SES) in patients undergoing percutaneous coronary intervention. It is unclear whether there are differences in safety and efficacy between EES and SES during long-term follow-up. Using propensity score matching, clinical outcome was c...
Article
One of the requirements for successful ankle arthrodesis is adequate compression by the fixation across the fusion surfaces. A common screw construct for ankle fusion is three crossed screws from proximal-to-distal. Because the screws are inserted nearly orthogonal to each other, it is possible minimal additional compression is obtainable once the...
Article
This study examined the effects (affective reactions, cognitive reactions and processing, perceived benefits and barriers and intent to screen) of targeted peripheral+evidential (PE) and peripheral+evidential+socio-cultural (PE+SC) colorectal cancer communications. This study was a two-arm randomized control study of cancer communication effects on...
Conference Paper
Background. Newspapers continue to depend on alcohol and tobacco advertisements for revenue. No study has investigated whether such service and product advertising may relate to editorial coverage. Purpose. The study evaluates whether the amount and type of alcohol and tobacco advertising in newspapers affects editorial content within these newspap...
Article
Compare effects of narrative and informational videos on use of mammography, cancer-related beliefs, recall of core content and a range of reactions to the videos. African American women (n=489) ages 40 and older were recruited from low-income neighborhoods in St. Louis, MO and randomly assigned to watch a narrative video comprised of stories from...
Article
Epidemiologic studies have shown that sleep duration is associated with overall mortality. We conducted a systematic review of the associations between sleep duration and all-cause and cause-specific mortality. PubMed was systematically searched up to January, 2008 to identify studies examining the association between sleep duration and mortality (...
Article
The progression of subtalar and midfoot arthritis is well documented following ankle arthrodesis, and gait analysis has suggested that a functional gait pattern following arthrodesis may be due to tarsal hypermobility compensating for lost tibiotalar motion. We present a prospective radiographic study comparing the pre- and postoperative range of m...
Article
s: Frontiers in Cancer Prevention Research 2008 B20 Background Women undergoing adjuvant chemotherapy for breast cancer treatment complain of cognitive difficulties especially with memory, word recall, and concentration. Commonly referred to as “chemo brain”, some studies suggest that up to 40 to 80% of women may experience some decline in cogni...
Article
B19 Background Aromatase inhibitors are widely used for the treatment of post-menopausal breast cancer. Arthralgias and myalgias are major side effects. A case-control study was conducted to determine the prevalence and severity of musculoskeletal symptoms among women treated with aromatase inhibitors compared to women without a history of cancer a...
Article
This study was conducted in an ongoing community-based cohort study to examine the prevalence of non-cancer adverse health conditions among cancer survivors and the association of these conditions with self-rated health and functional status. Data were analyzed from CLUE II, a community-based cohort study in Washington County, Maryland that began i...
Article
Full-text available
The primary aim of this study was to examine prospectively the associations between 5 peroxisome proliferator-activated receptor (PPAR) single nucleotide polymorphisms (SNPs) and cardiovascular morbidity and mortality in a community-based cohort study in Washington County, Maryland. Data were analyzed from 9,364 Caucasian men and women participatin...
Article
Full-text available
To evaluate the attitudes, knowledge, and beliefs of future physicians regarding smoking cessation and tobacco-related issues and the development of these attributes during the course of medical education. In a cross-sectional survey, questionnaires were completed by 298 first- and fourth-year medical students at three medical schools from 2003 thr...
Article
The purpose of the study was to examine the interaction between parental smoking status and parental attitudes, as measured by positive parental concern, on the risk of adolescent cigarette smoking. Parental smoking and parental concern about smoking were measured in a cross-sectional study of 37,244 students, a random sample of Maryland middle and...

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