Binal Patel

Binal Patel
Saffrony Institute of Technology · Department of Information Technology

About

7
Publications
348
Reads
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10
Citations

Publications

Publications (7)
Article
The pulmonary route of administration offers several advantages. First, the lung has a large surface area for drug absorption, ranging from 100 to 140 m2. In addition, the alveolar epithelium has permeability that allows for rapid absorption of solutes. Because the mucociliary clearance of the alveolar lung tissue is slower than that of the bronchi...
Article
Oral delivery is the most convenient and the most acceptable route. However, insulin by itself is degraded by intestinal enzymes and is not absorbed intact across the gastrointestinal mucosa. Now, a day gelatin, trypsin coated capsule, pill, pellets may be available. It has some disadvantages; a lot of the insulin will be wasted before it gets wher...
Article
Microneedle-based vaccination with the current anthrax vaccine produced an equally effective immune response to intramuscular injection in rabbits using smaller dosage say researcher from Maryland and North Carolina. In the study researchers compared the efficacy of immunizing rabbits with the current anthrax vaccine intradermally using a microneed...
Article
Advances in the processing of materials on a micro-scale have led to the development and introduction of devices that employ very small needles. That has significant potential in devices for diagnostics, healthcare monitoring and drug delivery by mechanically perforating the outer skin layer and allowing for transdermal drug absorption or fluid sam...
Article
Microneedles find widespread use; researchers must perfect the techniques for optimally inserting them into the skin, and complete the integration of microneedles into a full diagnostic, monitoring or drug delivery system. Microneedles are expected to be less painful than conventional hypodermic needles because they are too small to significantly s...
Article
Large, porous particles with a mean geometric diameter of 10 µm. An increase in the size of aerosol particles results in a reduced fractional surface area (or likelihood) of particle-particle contact in a dry powder (or liquid suspension) and thus in less tendency to aggregate. This diminished aggregation means that less energy is required to aeros...
Article
Advancements in the development of ultra-fine drug molecules and peptides suitable for pulmonary delivery have created the requirement for novel handling, metering and drug dispensing techniques; while circumventing the problem of agglomeration (usually solved by mixing the active drug formula with Excipient. Inhalation has long been established in...