Bikash Debnath

• M.pharm, B. pharm
• Researcher at Tripura University

BACKGROUND The ancient medicinal herb known as croton joufra, which originated in northeastern India, is still used today in folk medicine to treat a wide range of illnesses. Phytochemicals are naturally occurring active compounds found in plants that provide various biological activities in humans and animals. METHODS Soxhlet extraction was used...

Background Fish and rice are very popular among the common people of Tripura. Different types of processed fish are available in Tripura, and they are very popular because of their taste and odor. They are the primary source of omega-3 polyunsaturated fatty acids. analysis of Atherosclerosis activities of processed fish samples of Tripura has not b...

Rapid growth in nanotechnology, also known as 21st-century technology, is occurring in response to the increasing diversity of diseases. The development of safe and effective drug delivery methods to enhance bioavailability is of paramount importance. Researchers have focused on creating safe, cost-effective, and environmentally friendly nanopartic...

Theranostics is an innovative field that utilizes nanotechnology and nanoparticles for a wide range of medical, diagnostic, and imaging applications. Therapeutic payloads, such as chemotherapeutic drugs, nucleic acids, and medicinal proteins or peptides, can be enclosed within nanoparticles or bonded to their surface for controlled release and exte...

Metabolic syndrome characterized by inadequate insulin secretion. The world's 2.8% of the population is affected by diabetes, and it is projected to reach 4.4% by 2030. Recently plant-based products have given significant results for curing diabetics. In this review article, we have summarized the taxonomical classification, phytochemical investiga...

BACKGROUND Herbal nutraceutical dosage forms a dietary supplement that improves various chronic diseases. This study aimed to formulate and evaluate new herbal nutraceutical tablets and assess antihyperglycemic and antihyperlipidemia effects in ob/ob mice. METHODS A herbal nutraceutical tablet was prepared by the wet granulation method. Proximate...

Compared to traditional liquid chromatography, high-performance liquid chromatography (HPLC) delivers better results for analyzing unknown compounds. It permits faster resolution time, better peak shapes, repeatable responses, and greater precision. A comprehensive literature search has been conducted using online academic databases such as Google...

Diplazium esculentum belongs to the family Athyriaceae, an edible fern rich in micronutrients, beta-carotene, folic acid, and minerals like calcium, iron, and phosphorus. The present study aims to determine secondary metabolites and minerals content and evaluate the antioxidant and antidiabetic activities of young fronds of Diplazium esculentum. Th...

Alkaloids are waste products of plant metabolic processes, containing at least one nitrogen atom in the heterocyclic ring. They serve a wide variety of physiological functions in humans and animals. Metabolism plays a central role in regulating the toxicity of various phytochemicals. Available literature of biological sources and metabolism study o...

Nutraceuticals are food-based drugs that are used as dietary supplements to minimize chronic diseases. Diabetes is one of the most common chronic diseases all over the world. Recently, herbal nutraceuticals have taken a promising role in treating diabetes. We aimed to develop herbal nutraceutical tablets and evaluate its anti-diabetic activity usin...

The use of Phytosomes for medicinal purposes is very much used to alleviate the harmful effects of diabetes, a common carbohydrate metabolic disease in all age groups. Over time, various newer therapies and medications have been developed to alleviate this disease. Although the traditional therapies seem to lower blood glucose levels to some extent...

Review Article

Amoebiasis is an infectious disease caused by Entamoeba histolytica (E. histolytica), the common symptoms are cramping, abdominal pain, watery or bloody diarrhea, and weight loss. Sometimes patients suffer amoebiasis as an asymptomatic behavior. In 1859 scientist W.D. Lambl first described the amoebiasis vector E. histolytica. In developing countri...

A chronic pathological condition; diabetes mellitus occurs in almost 90% of all diabetic cases globally. It is estimated that the number of diabetes patients will rise from 382 million in 2013 to 592 million by 2035 as per the data published by the Current International Diabetes Federation. Daily life style and day to day unhealthy food habits, dia...

A parasite of the Plasmodium species initiates malaria. The parasite is transmitted to communities through the bite of an infected mosquito. Malarial resistance towards the commonly used antimalarial agents is a genuine human health problem. Benzimidazole derivatives exhibit a wide range of antimalarial activities against Plasmodium falciparum (P....

Edible plants are used as valuable sources of food and medicine to prevent nutritional imbalance, illness, and maintenance of human health. This review covers botanical descriptions, phytochemicals studies, traditional comprehensions, dietary values, and biological activities of ten vegetable plants and eight fruit plants of Tripura, India. The boo...

Musa paradisiaca (Banana plant), which belongs to Musaceae, is a tropical plant-based fruit crop for Tripura, India. The main consumable parts of the banana plant are fruit, stem, and flower. This study aims to ethonomedicinal survey and determine the water-soluble (C, B1, B3, B6, folic acid) and fat-soluble (A, D3, E) vitamins of three consumable...

Medicinal plants are an immense source of biologically active substances. Ananas comosus is a fruit base medicinal plant belonging to the family Bromeliaceae. In English it is called 'pineapple'. Pineapple is one of the important tropical fruit in the China, India, Costa Rica, Brazil, Thailand, Philippines, Indonesia, Nigeria, and Colombia. 100 g o...

The coronavirus disease 2019 (COVID-19) first outbreak in Wuhan, China, and the infection is intense worldwide. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for COVID-19. The World Health Organization (WHO) confirmed total deaths had noted 4.20% globally (March 21, 2020). Between the intervals of four months (July 21,...

The archeological and historical record shows that people across Asia, Europe, and Africa used alkaloidal drugs as early as 2000 BCE. Alkaloids are heterocyclic rings consisting of at least one nitrogen atom. They are the waste products of plant metabolites and serve a wide variety of biological activities to human beings. Nicotine, cytosine, atrop...

Melocanna baccifera is a unique bamboo naturally distributed in hilly area of northeast India, belonging to the grass family of Poaceae. In Northeast India young bamboo shoots are used as a vegetable due to the presence of high nutritional value. The aim of this study was to determine secondary metabolites, proximate composition, minerals, heavy me...

Plant polyphenols are fast-growing food products for the health beneficial properties. Ellagic acid (EA) is a fused four-ring polyphenol. It is present in the form of ellagitannin in plants. A significant quantity of EA was found in raspberry, blackberry, strawberry, cloudberry, and pomegranate. The present article provides ample information on the...

Background Musa paradisiaca (Banana plant), which belongs to the family of Musaceae, is a well-known herbaceous flowering edible plant. The flower, fruit, and stem part of the plant have been used for nutrients and health benefits. Objective The aim of this study is to determine the secondary metabolites, proximate composition, minerals, heavy met...

Abstract: Alkaloids are plant secondary metabolite. They are well known nitrogen-containing natural bioactive compounds. Cutting edge research is going on alkaloids to unravel novel therapeutic approaches. Literature reveals that alkaloids contribute multiple biological activities and some alkaloids transform into active metabolites too. In this re...

Abstract: Alkaloids are plant secondary metabolite. They are well known nitrogen-containing natural bioactive compounds. Cutting edge research is going on alkaloids to unravel novel therapeutic approaches. Literature reveals that alkaloids contribute multiple biological activities and some alkaloids transform into active metabolites too. In this re...

In this study, the determination of secondary metabolites, anti-oxidant and cytotoxic activity of seed coat of Macrotyloma uniflorum were carried out in different solvents (petroleum ether, chloroform, ethanol, and water), according to their increasing polarity. Alkaloid and tannin content was analyzed by simple titrimetric method. Colorimetric met...

Edible plants are vital in our diet as well as have ethno medicinal values. They are important food and highly beneficial for the maintenance of health and prevention of diseases. The genus Typhonium (Family: Araceae) is a leafy vegetable plant comprises of about 69 species of tuberous perennial herbs. It is widely distributed in tropical region of...

Objective: Objective of the present work was qualitative and quantitative estimation of alkaloids and phenolics of five edible cucurbitaceous plants and to evaluate their antibacterial activity against some human pathogenic bacteria. Methods: Total alkaloid present was determined by acid-based titrimetric methods using methyl red as an indicator an...

Central nervous system (CNS) drug development will be biology driven. Due to absence of functional platform for CNS drug targeting since, the large molecules pharmaceuticals cannot be delivered to brain. About 1.5 billion people worldwide are suffering from various type of central nervous system (CNS) disorders. Overcome to this problem modern phar...