Bidyut Goswami

• Professor at West Bengal University of Health Sciences

Bone marrow study is of fundamental importance in most haematological disorders including haematological malignancies, carried out to permit cytological assessment and for other specialized investigations. Trephine biopsy gives histological details of marrow including cellularity, fibrosis and reveals the causes of dry tap. Finer cytomorphological...

Background & objectives A hike in dengue cases was recorded in last two years, resulting from both single and multiple-serotypes of dengue virus (DENV) and secondary infections, culminating in significant hospitalizations and deaths in India. This study focuses on evaluating symptomatic and haematological parameters in acute dengue patients of the...

Colorectal adenocarcinoma, the most prevalent form of colon cancer, originates in the glandular structures of the intestines, presenting histopathological abnormalities in affected tissues. Accurate gland segmentation is crucial for identifying these potentially fatal abnormalities. While recent methodologies have shown success in segmenting glands...

Regardless of the suspected cause of death, the post-mortem examination should always be done where deaths (related to sudden and unexpected demise), come under the jurisdiction to determine the cause and manner of the death. Various incidental findings are identified during microscopic examination which may or may not be the contributing factor fo...

Background Platelet indices (PI) have emerged as a useful tool for identifying platelet dysfunction and cardiovascular risk in various diseases, including diabetes mellitus (DM) and hypertension. This study aimed to investigate the variation of PI in patients with DM and hypertension in the northern part of West Bengal. Materials and Methods A cas...

Littoral cell angioma (LCA) of the spleen, a rare vascular tumor, is usually asymptomatic, often discovered incidentally and a majority of them are benign in nature. A 20-year-old boy with a history of blunt abdominal trauma, who underwent splenectomy showed the presence of a capsular tear and variegated outer surface on gross examination of the sp...

Till date, histopathological examination of concerned tissue by light microscopy is considered to be the gold standard and most acceptable method for the final diagnosis of disease processes. Sometimes, examination of serial sections, i.e., consecutive sections obtained from a histopathologically processed tissue specimen using a microtome, plays a...

Background: Cervical cancer (Ca Cx) the 4th common cancer has a high mortality rate. Human Papilloma Virus (HPV) is chiefly responsible for a long latent period to progress from preinvasive to invasive Ca Cx. So it can be prevented by screening procedures such as visual inspection with acetic acid (VIA), conventional cervical PAP smear (CP), liquid...

Meckel’s diverticulum (MD), first documented by Wilhelm Fabricius Hildanus in 1598 as a small bowel diverticulum and later detailed by Johann Friedrich Meckel in 1809, is a remnant of the vitellointestinal duct connecting the fetal gut with the yolk sac. It is a true diverticulum, comprising of all the layers of the bowel wall. The commonly cited “...

Histopathological findings depend on the distinction between normal and subtle changes in mucosal tissues. These distinctions are made based on the nature of the cell lining, nuclear hyperchromasia and cyto-architecture of glands. Diagnosis is mostly based on the experience of the pathologists, which is a subjective procedure. This research focuses...

Introduction: Oral cancer is the sixth most common malignancy worldwide and accounts for 30% of all cancers in India, with 5-year survival rate, except when diagnosed in the early stages. Hence, early diagnosis of oral cancer is very much essential for the sake of the patient. However its burden on the economy for providinghealthcare is substantial...

Northern West Bengal, popularly known as North Bengal, is a dengue-endemic area, which has been severely affected by Dengue in the past few years resulting in massive hospitalizations and deaths. Genetic characterization of the circulating endemic dengue virus (DENV) serotypes is of paramount importance for the epidemiological understanding of the...

Introduction: Inherited disorders of hemoglobin synthesis form the most common single gene defect in man. Genetic carrier screening plays the most important role in prevention of birth of baby with these entities. A normal hemoglobin concentration does not necessarily signify a normal hemoglobin structure. Hence it is important to screen for abnorm...