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University of California, Riverside
Department of Cell Biology and Neuroscience
Bhuvaneswari Chinthirla

Bhuvaneswari Chinthirla
University of California, Riverside | UCR · Department of Cell Biology and Neuroscience

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Publications

411

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Citations

6 Research Items

14 Citations

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Publications

Figure 4. Abnormal glycemia reduction after insulin challenge in male...

Glucoregulatory Reprogramming in Male Mice Offspring Induced by Maternal Transfer of Indoor Flame Retardant Endocrine Disruptors

Preprint

Full-text available

Oct 2022

Polybrominated diphenyl ethers (PBDEs) are commercially used as indoor flame retardants that penetrate biota and bioaccumulate in human tissues, including breast milk. PBDEs have been associated with endocrine disruption, diabetes and metabolic syndrome (MetS) in humans and animals. However, their sex-specific diabetogenic effects are not completel...

FIGURE 6 Sex-dependent alterations of hypothalamic energy balance genes...

DE-71 exposure has minimal effects on body composition.

Developmental exposure to indoor flame retardants and hypothalamic molecular signatures: Sex-dependent reprogramming of lipid homeostasis

Article

Full-text available

Sep 2022

Polybrominated diphenyl ethers (PBDEs) are a class of flame-retardant organohalogen pollutants that act as endocrine/neuroendocrine disrupting chemicals (EDCs). In humans, exposure to brominated flame retardants (BFR) or other environmentally persistent organic pollutants (POPs) such as polychlorinated biphenyls (PCBs) and novel organophosphate fla...

Maternal dosing paradigm for DE-71 produces BDE congener penetration in...

Early-life exposure to DE-71 induces deficits relevant to core symptoms...

Exposure to L-DE-71 but not H-DE-71 reduces long-term social...

Perinatal exposure to L-DE-71 compromises short-term novel object...

Perinatal exposure to DE-71 does not alter general olfaction function...

Persistent autism-relevant behavioral phenotype and social neuropeptide alterations in female mice offspring induced by maternal transfer of PBDE congeners in the commercial mixture DE-71

Article

Full-text available

Jan 2022

Polybrominated diphenyl ethers (PBDEs) are ubiquitous persistent organic pollutants (POPs) that are known neuroendocrine disrupting chemicals with adverse neurodevelopmental effects. PBDEs may act as risk factors for autism spectrum disorders (ASD), characterized by abnormal psychosocial functioning, although direct evidence is currently lacking. U...

Persistent autism-relevant phenotype produced by in utero and lactational exposure of female mice to the commercial PBDE mixture, DE-71

Preprint

Full-text available

Jul 2021

Dosing and testing paradigm used for perinatal and adult exposure to...

Hepatic BDE congener analysis of DE-71-exposed mouse dams and their...

DE-71 exposure produces elevated fasting blood glucose (FBG) in...

DE-71 exposure produces greater glucose intolerance after perinatal...

DE-71 exposure causes less glycemia reduction and delayed glucose...

Maternal transfer of environmentally relevant polybrominated diphenyl ethers (PBDEs) produces a diabetic phenotype and disrupts glucoregulatory hormones and hepatic endocannabinoids in adult mouse female offspring

Article

Full-text available

Oct 2020

Abstract Polybrominated diphenyl ethers (PBDEs) are brominated flame retardant chemicals and environmental contaminants with endocrine-disrupting properties that are associated with diabetes and metabolic syndrome in humans. However, their diabetogenic actions are not completely characterized or understood. In this study, we investigated the effect...

Maternal Transfer of Environmentally Relevant Polybrominated Diphenyl Ethers (PBDEs) Produces a Diabetic Phenotype and Disrupts Glucoregulatory Hormones and Hepatic Endocannabinoids in Adult Mouse Female Offspring

Preprint

Full-text available

Sep 2020

Polybrominated diphenyl ethers (PBDEs) are brominated flame retardant chemicals and environmental contaminants with endocrine-disrupting properties that are associated with diabetes and metabolic syndrome in humans. However, their diabetogenic actions are not completely characterized or understood. In this study, we investigated the effects of DE-7...