Bhimanagouda S Patil

Bhimanagouda S Patil
Texas A&M University | TAMU · Vegetable & Fruit Improvement Center

Ph.D.

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415
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Publications

Publications (415)
Article
The orexigenic hormone ghrelin and its receptor, growth hormone secretagogue receptor (GHS-R), have been extensively studied in the last two decades, revealing that ghrelin signaling has important implications in health and disease. Metabolic diseases, such as obesity and diabetes, are often accompanied by low-grade chronic inflammation, that has b...
Preprint
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Background Vine decline disease (VDD) caused by the fungus Monosporascus cannonballus (MC), is a major threat to melons (Cucumis melo L.) production worldwide. Nonetheless, little is known about the metabolites produced during the interaction of melon plants with this pathogen. Thus, the goal of this study was to identify and measure quantities as...
Book
Melon (Cucumis melo) is an important diploid crop grown worldwide. To understand the development of Melon fruits, time-course gene expression profiling was conducted for two field-grown melon varieties (Western shipper; F39 and Tuscan da Vinci; TTDV) using the Next Generation Sequencing (NGS) approach. A total of 449014207 reads were mapped to the...
Article
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A non-invasive and non-destructive technique, Raman spectroscopy, was explored to distinguish different maturity stages (20, 30, 40, and 50 days after anthesis) of watermelon (Citrullus lanatus) fruits from four cultivars: Fascination, Orange Crisp, Amarillo and Crimson Sweet. Spectral acquisition from the fruit surface was carried out at the wavel...
Article
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Volatile compounds produce the aroma of fruits such as melons (Cucumis melo) and therefore play a key role in fruit quality. Here, we optimized experimental parameters to evaluate the effect of blending time, extraction temperature and time, different fibers, sample weight, different columns, and salt on the volatile composition of melons was perfo...
Article
Accurate, rapid quantitation of the capsaicinoid and capsinoid compounds produced by peppers (Capsicum spp.) is essential to assess quality. Here, we developed a rapid ultra-high performance liquid chromatography method for the simultaneous separation of five major capsaicinoids and three major capsinoids from peppers. Optimal chromatographic separ...
Article
The sensory and functional quality attributes of muskmelons (Cucumis melo L.), such as flavor, sweetness, color, and texture, determine consumer preferences. Genetic makeup primarily regulates these traits, but environmental factors such as soil type, irrigation, and temperature affects yields and quality. Here, we investigated variation in quality...
Article
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Cucumis melo L is one of the most commercial and economical crops in the world with several health beneficial compounds as such carotenoids, amino acids, vitamin A and C, minerals, and dietary fiber. Evaluation of the volatile organic compounds (VOCs) in different melon (Cucumis melo L.) breeding lines provides useful information for improving frui...
Article
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Bitter melon (Momordica charantia L.) has been used to manage diabetes and various inflammatory conditions. While studies have explored the use of bitter melon to manage these conditions, the bioactive components and molecular mechanisms mediating the anti-inflammatory effects remain elusive. In the current study, acetone and methanol extracts of b...
Article
Full-text available
Characterizing the diverse melon cultivars for nutrition aids in crop improvement and promoting a healthy diet. Here, we used in vitro assays to characterize the nutritional qualities and health-beneficial effects of 30 melon (Cucumis melo L.) genotypes, including 10 improved cultivars, 16 landraces, and 4 wild types collected from different parts...
Article
The nutritional quality of many fruits and vegetables is regulated by pre-harvest management factors that can be manipulated to attain desired quality standards. In this study, the impact of seed nanopriming on the phytochemical composition of watermelon was studied. Seeds of two watermelon varieties namely: River Side (diploid) and Maxima (triploi...
Article
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Melon (Cucumis melo L.) fruits contain multiple health-promoting compounds, including phenolic compounds, which are antioxidants. Accurate measurement of antioxidant activities and total phenolic contents (TPCs) require an efficient solvent extraction. In this study, we evaluated free radical scavenging activity and TPC of melon extracts extracted...
Article
The efficacy of plant-based antimicrobials against Salmonella Newport and Listeria monocytogenes on melon rinds was evaluated. Four cantaloupe and 3 honeydew melon varieties grown in Georgia, Arizona, Texas, North Carolina, Indiana and California were tested. Melon rinds (10 g pieces) were inoculated with 5–6 log CFU/10 g rind of S. Newport or L. m...
Article
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The use of nanoscale nutrients in agriculture to improve crop productivity has grown in recent years. However, the bioefficacy, safety, and environmental toxicity of nanoparticles (NPs) are not fully understood. Herein, we used onion bulb extract to synthesize manganese oxide nanoparticles (MnO-NPs). X-ray diffraction, X-ray photoelectron spectrosc...
Article
Full-text available
Accurate, rapid quantitation of key antioxidants such as carotenoids is important for assessment of food quality. Carotenoids are lipid-soluble pigments that are susceptible to oxidation due to their highly conjugated carbon-carbon double bonds. Therefore, the present work focuses on improving sample preparation to facilitate rapid analysis of caro...
Article
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Diabetes mellitus is a chronic disease and one of the fastest-growing health challenges of the last decades. Studies have shown that chronic low-grade inflammation and activation of the innate immune system are intimately involved in type 2 diabetes pathogenesis. Momordica charantia L. fruits are used in traditional medicine to manage diabetes. Her...
Article
Melon is one of the most popular fruits worldwide and has been bred into various cultivars. RNA-sequencing using healthy melon fruit was performed to determine differences in gene expression among cultivars. Unexpected RNA-seq results revealed that viruses asymptomatically infected fruits at a high frequency (16 of 21 fruits examined were infected)...
Article
In our recent study, we have demonstrated certain limonoids isolated from citrus seeds have induced apoptosis in human pancreatic (Panc-28) cells. In the current study, limonin, nomilin and limonexic acid (LNA) were investigated for possible mode of cytotoxicity in cultured pancreatic cancer (Panc-28) cells. All three limonoids inhibited Panc-28 ce...
Article
This study used ultra-high-performance liquid chromatography combined with ion-trap time-of-flight mass spectrometry (UHPLC-QTOF-MS) and complementary metabolomics approaches to investigate the effects of three processing techniques (blending, high-speed centrifugal juicing, and low-speed juicing) on the phytochemical profiles and antioxidant activ...
Article
Tomato (Solanum lycopersicum) fruit is a rich source of health-promoting compounds, and epidemiological studies show that tomato consumption may reduce the risk of chronic diseases. This study compared the effect of genotype, production system, and their interaction on eight tomato varieties grown in the open-field (OF) or net-house (NH), a structu...
Article
Melon (Cucumis melo) is an important diploid crop with a wide variety of flavors due to its distinct aromatic volatile organic compounds (VOC). To understand the development of VOC profiles during fruit development, we performed metabolomic and transcriptomic analysis of two cantaloupe varieties over the course of fruit development. A total of 130...
Article
Full-text available
Background Fusarium oxysporum f. sp. niveum (FON) causes Fusarium wilt in watermelon. Several disease-resistant watermelon varieties have been developed to combat Fusarium wilt. However, the key metabolites that mount defense responses in these watermelon varieties are unknown. Herein, we analyzed hormones, melatonin, phenolic acids, and amino acid...
Article
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The bacterial pathogen 'Candidatus Liberibacter solanacearum' (Lso) is transmitted by the tomato potato psyllid (TPP), Bactericera cockerelli, to solanaceous crops. In the present study, the changes in metabolic profiles of insect-susceptible (cv CastleMart) and resistant (RIL LA3952) tomato plants in response to TPP vectoring Lso or not, were exam...
Article
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Onion is among the most widely cultivated and consumed economic crops. Onions are an excellent dietary source of polyphenols and nutrients. However, onions phytonutrient compositions vary with cultivars and growing locations. Therefore, the present study involved the evaluation of polyphenol, nutritional composition (proteins, nitrogen, and mineral...
Article
Full-text available
Cantaloupe is a good dietary source of amino acids, including γ-aminobutyric acid (GABA), glutamine, and citrulline. However, the levels of these amino acids vary among different cantaloupe varieties grown in different locations. Understanding the variation in amino acid contents provides fundamentally important information for quality control and...
Article
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BACKGROUND Polyphenol oxidase (PPO) and peroxidase (POD) are key shelf‐life and defense‐response associated enzymes. Thus, the activities of PPO and POD enzymes are usually assessed to check the quality of food samples and to understand the physiological response of plants to different stresses. However, the outcome of PPO and POD activity assessme...
Article
Full-text available
Accurate assays of plant antioxidants and other phytochemicals require efficient extraction conditions and enable rigorous assessments of crop varieties and production systems. This study assessed the extraction of phytochemicals and antioxidants from conventionally or organically grown red and golden beets (Beta vulgaris L.), using twenty solvent...
Article
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Herein, we used a metabolomics approach to identify biomarkers of Fusarium wilt infection in watermelon. The observed metabolic profiles of infected plants were genotype specific and distinct in leaf and stem tissues compared with roots. The leaf tissue of Fusarium wilt-symptomatic plants had detectable or elevated levels of jasmonic acid–isoleucin...
Article
Sweet or low-pungency onions have become popular in fresh market onion production and are commonly produced using low sulfur soil and/or innate low-pungency cultivars in specific regions. However, there have been very limited breeding efforts to create true low-pungency cultivars. This study reports the process and progress of a recurrent selective...
Article
Seed priming is a promising approach to improve germination, emergence, and seedling growth by triggering pre-germinative metabolism and enhancing seedling vigor. Recently, nanopriming gained importance in seed improvement due to the small size and unique physicochemical characteristics of nanomaterials. In the present study, silver and gold nanopa...
Article
Full-text available
Seed priming uses treatments to improve seed germination and thus potentially increase growth and yield. Low-cost, environmentally friendly, effective seed treatment remain to be optimized and tested for high-value specialty crop like watermelon (Citrullus lanatus) in multi-locations. This remains a particularly acute problem for triploids, which p...
Article
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Plant pigments such as anthocyanins and carotenoids have been shown to be beneficial to human health. Therefore, carrot lines of different colors have been recently developed. This study aimed to characterize terpenoid, carotene, anthocyanin, and soluble solids content and antioxidant activity levels in orange, yellow, black, and purple carrots to...
Article
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Short-day onions (Allium cepa L.) grown in the southern regions of the United States are commonly undercut and then dried for a few days before the bulbs are clipped and harvested. We conducted a study to evaluate the effects of leaf cutting on bulb weight and pungency of short-day onions after plant lifting in ‘TG 1015Y’, ‘Legend’, and ‘Texas Earl...
Article
Fruits and vegetables have long been studied for their potential roles in reducing certain cancer risks. Herein, lyophilized BetaSweet carrots were extracted with hexane, methanol, and water and their chemical constituents were identified by UPLC-QTOF-HR-MS. Methanol extracts exhibited significantly higher radical scavenging activity compared with...
Article
CIRCADIAN CLOCK-ASSOCIATED1 (CCA1), a well-known central circadian clock regulator, coordinates plant responses to environmental challenges. Its daily rhythmic expression in Arabidopsis confers host resistance to the caterpillar Trichoplusia ni. However, it is unclear whether CCA1 plays a role in defense against phloem sap-feeding aphids. In this s...
Article
Green nanotechnological approach is a rapidly expanding in sustainable precision agriculture that promises to revolutionize food production. In the present study, nanoparticles (NPs) were synthesized using efficient green process involving the use of plant extracts as reducing agents. Silver nanoparticles (AgNPs) and gold nanoparticles (AuNPs) were...
Article
The present study investigated the phenolic fingerprinting of untargeted metabolites using UPLC-QTOF-MS combined with chemometrics to identify potential metabolites in 30 commercial juices belongs to thermal and cold processed juices. A total of 47 compounds were tentatively identified using high resolution mass spectra. Kaempferol and quercetin gl...
Article
Bitter melon (Momordica charantia) has been used to manage diabetes and related conditions in various parts of the world. In the present study, ten compounds were isolated from acetone and methanol extracts of bitter melon. The chemical structures of compounds were unambiguously elucidated by 1D, 2D NMR, and high-resolution mass spectra. Identified...
Article
Bile acids are cholesterol-derived steroid molecules that serve various metabolic functions, particularly in the digestion of lipids. Gut microbes produce unconjugated and secondary bile acids through deconjugation and dehydroxylation reactions respectively. Alterations in the gut microbiota have profound effects on bile acid metabolism, which can...
Article
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The proposed analytical method reports the separation and quantification of 21 amino acids including L-citrulline from fresh vegetables and commercial juices using a C 8 column. Optimal separation conditions for amino acids analysis were obtained with 20 mM sodium acetate (solvent A) and water with organic modifier acetonitrile and methanol (solven...
Article
The current study was designed to characterize the metabolite profile and bioactivity of two commercial bitter melon (Momordica charantia Linn.) genotypes. UPLC-high resolution mass spectrometry (HRMS) was used to identify 15 phenolic and 46 triterpenoids in various bitter melon extracts. Total phenolic levels were the highest (57.28 ± 1.02) in met...
Article
Full-text available
Antioxidant levels are key parameters for studies of food quality, stress responses, and plant health. Herein, we have demonstrated that excised leaf disc has both radical scavenging activity and reducing power, and used this concept to develop 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), and...
Article
In the present study, onion extract was used for green synthesis of iron oxide nanoparticles (Fe-NPs). The X-ray diffraction, X-ray photoelectron spectroscopy, and high-resolution transmission electron microscopy characterizations demonstrated that the biosynthesized Fe-NPs were mainly of low-crystalline or amorphous Fe2O3 with diameter of 19-30 nm...
Article
Full-text available
Momordica charantia L., commonly known as bitter melon, belongs to the Cucurbitaceae family. Various in vitro and in vivo studies have indicated that extracts of bitter melons have anti-diabetic properties. However, very little is known about the specific purified compounds responsible for these antidiabetic properties. In the present study, 3β,7β,...
Chapter
The genus Brassica comprises a large group of herbaceous plants, including many vegetables that originated in the Mediterranean region. These vegetables contain various phytochemicals such as phenolic acids, flavonoids, glucosinolates, and their hydrolyzed products. Among the Brassica vegetables, Brussels sprouts (Brassica oleracea var. gemmifera)...
Chapter
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Curcumin, (1E,6E)-1,7-Bis (4-hydroxy-3-methoxyphenyl) hepta-1,6-diene-3,5-dione, has potential anti-cancer and other health-promoting activities. Despite its promising pharmacological properties, therapeutic applications of curcumin have been impeded by its limited bioavailability due to its low aqueous solubility at acidic and physiological pH, lo...
Article
Multicomponent therapy has gained interest for its potential to synergize and subsequently lower the effective dose of each constituent required to reduce colon cancer risk. We have previously showed that rapidly cycling Lgr5 stem cells are exquisitely sensitive to extrinsic dietary factors that modulate colon cancer risk. In the present study, we...
Article
In the present study, the influence of production systems (net-house and open-field) on volatile profiles of three Texas A&M University (TAMU) and five commercial tomato varieties was investigated. Forty metabolites were determined using headspace solid phase microextraction (HS-SPME) equipped with gas chromatography and mass spectrometry (GC–MS)....
Article
Full-text available
Introduction In recent years, growers have used various production types, including high-tunnel systems, to increase the yield of tomatoes (Lycopersicon esculentum). However, the effect of high-tunnel cultivation, in comparison to conventional open-field production, on aroma and flavor volatiles is not fully understood. Objectives To optimize the...
Article
The cover image, by Noorani Barkat et al., is based on the Research Article Effect of harvest time on the levels of phytochemicals, free radical‐scavenging activity, α‐amylase inhibition and bile acid‐binding capacity of spinach (Spinacia oleracea), DOI: 10.1002/jsfa.8862. The cover image, by Noorani Barkat et al., is based on the Research Article...
Article
BACKGROUND In the U.S., Momordica charantia, is relatively unknown and usually found in specialty markets. In this study, cultivation of five bitter melon cultivars grown in field conditions in College Station, Texas, was evaluated. Additionally, ascorbic acid, amino acids and phenolic compounds were quantified from various cultivars grown at diffe...
Article
A rapid, sensitive analytical method using ultra-high-pressure liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (UHPLC-HR-QTOF-MS) was developed for the identification and quantification of flavonoids from spinach. The extraction efficiency of flavonoids was evaluated by different solvents such as acetone, ethanol, met...
Article
Full-text available
Dandelion (Taraxacum officinale) var. Garnet Stem was harvested from Texas and New Jersey for identification, quantification of phytochemicals, measurement of free radical scavenging activity, and bile acid binding capacity. The red midrib and petioles were extracted with methanol or ethanol and with or without water in combination with four differ...
Article
Nitrate and polyphenols from the diet may enhance the production and bioavailability of nitric oxide, a radical signaling molecule critical for cardiovascular health. Understanding the stability of these bioactives in beetroot and arugula juices is important for their functions. In this study, the stability of nitrate and phenolics in beetroot and...