Bhawaniprasad Bag

Sambalpur University · Department of Biotechnology and Bioinformatics

Insight into the interaction of the uranyl( vi ) complex with bovine serum albumin was gained through comprehensive spectroscopic and molecular docking studies.

Now‐a‐days ternary organic solar cells (OSCs) based on all‐small‐molecules found to have the convenient strategy towards the high‐performance and stable devices. Herein, two coumarin‐based dyes C4 and C4‐CN were designed and synthesized with a simple synthetic route. The molecules display different intra‐ and intermolecular interactions in the soli...

Interaction aspects of uranyl(VI) complexes as well as the coordinated ONNO-donor ligand with bovine serum albumin (BSA) were investigated by the fluorescence spectroscopy and computational insights. Under optimal physiological condition, it was observed that there was significant decrease in fluorescence intensity of BSA upon interaction with uran...

The choice of molecular material plays a crucial role in improving the performance of organic solar cells. Herein, two coumarin‐based small molecules were designed and synthesized in which the π‐system is extended by the introduction of double bonds. The molecules are differed by the attachment of central acceptor units. The replacement of the carb...

A rapid and high yield microwave assisted synthesis of a series of novel 7,9-bis-(arylidene)-4-methyl-2,6,10-triphenyl-2,3-diazaspiro[4,5]dec-3-ene-1,8-dione has been explored. The spiro diarylidene derivatives having nitrogen atom and ?, ?-unsaturated ketone moiety were synthesized through aldol condensation between 4-methyl-2,6,10-triphenyl-2,3-d...

A series of fluorophoric and structurally diverse thiazoloquinazoline derivatives were synthesized in a one-pot multicomponent cascade reaction using a microwave irradiation technique. The unique structural arrangement of the synthesized compounds encouraged us to design a new type of bioactive molecular receptor. This receptor interacts with HSO4...

Drug solubility is an important parameter to determine the biological efficacy of a drug. To avoid the difficulties of drug insolubility, macrocyclic hosts like cyclodextrins (CDs) are used to enhance the solubility through formation of inclusion complex. CDs are popular as drug-delivery vehicle as it dissociates the drug molecule at its binding de...

The rapid spread of COVID-19 compelled the infected nations to close down their educational institutions to check the rigor of spread. In such context, to provide uninterrupted education to the students, virtual education through internet was widely adopted. This paper throws a light on how the students engaged in virtual education are exposed t...

The serotonergic systems are the most important therapeutic targets for neurological disorders. Many serotonergic drugs have been used to treat neurological disorders, which are well known for their adverse side effects because of the off-target interactions. Development of selective ligands for a specific target is the suitable approach to minimiz...

The present manuscript reports the synthesis, structural confirmation, thermodynamics and vibrational spec-troscopic studies of an important biorelevant molecule, named N-iso-butyl, S-2-nitro-1-phenylethyl dithiocar-bamate in the gas phase. We have found a total of five low lying energy structures of N-iso-butyl, S-2-nitro-1-phenylethyl dithiocarba...

In fullerene-free single-junction organic solar cells despite small interfacial energy offset between the donor and acceptor materials efficient hole transfer occurs, resulting in power conversion efficiencies (PCE) >16%. Here, we demonstrate efficient organic solar cells by simple structural modulation of simple coumarin-based molecular donors whi...

The present manuscript reports the synthesis, structural confirmation, thermodynamics and vibrational spectroscopic study of an important biorelevant molecule, named N-iso-butyl, S-2-nitro-1-phenylethyl dithiocarbamate in the gas phase. We have found a total of five low lying energy structures of N-iso-butyl, S-2-nitro-1-phenylethyl dithiocarbamate...

The present manuscript reports the synthesis, structural confirmation, thermodynamics and vibrational spectroscopic study of an important biorelevant molecule, named N-iso-butyl, S-2-nitro-1-phenylethyl dithiocarbamate in the gas phase. We have found a total of five low lying energy structures of N-iso-butyl, S-2-nitro-1-phenylethyl dithiocarbamate...

Eugenol is known for its beneficial health effects. However, its low bioavailability requires administration of higher doses to achieve the desired effect. Host-guest complexation is often employed in the transport of biologically relevant molecules, ensuring their higher bioavailability. In this work, we studied the host-guest complexation of euge...

Leishmaniasis is caused by Leishmania protozoan parasites transmitted by the female phlebotomine sandfly. The current treatment regimen of leishmaniasis is not up to the mark and there is a huge scope of improvement. Hence, the need to approve new drugs, a complete understanding of the pathophysiology of the parasite is required. Since polyamines a...

The on-going pandemic COVID-19 has emerged as a major health threat across the globe. At present, anti-viral drug discoveries are of great importance in combating the pandemic. Millets are known to contain numerous flavonoids with potential anti-viral properties. However, their anti-viral efficacy against SARS-CoV-2 is yet to be studied. The study...

The detection of hydroxylamine in an aqueous medium is challenging due to its very similar chemical reactivity to its nearest competitors such as hydrazine hydrate and primary amines. Moreover, the detection of hydroxylamine at neutral pH adds further complexity to the sensing phenomenon due to its poor reactivity in a neutral aqueous medium. In th...

Pectinolytic enzymes produced by a large variety of organisms are well characterized concerning their physiological and pathological activities during modification or degradation of the complex plant cell wall. The exponential growth in structural information of these enzymes over past decades has rendered insights into functionally relevant residu...

A purified alkaline thermotolerant bacterial lipase from Bacillus coagulans BTS-3 was immobilized on nylon-6 matrix activated by glutaraldehyde. The matrix showed ∼ 70% binding efficiency for lipase. The bound lipase was used to perform transesterification in n-heptane. The reaction studied was conversion of vinyl acetate and butanol to butyl aceta...