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Publications (25)
Introduction
Suspicious lung nodules on CT are typically investigated with a ¹⁸F-FDG PET-CT scan and a Herder score is calculated to guide management. BTS guidelines recommend that nodules with a score under 10% should be offered surveillance and over 70% surgery. However, for a score between 10 to 70%, management decisions are left to the multidis...
Background
There are no specific guidelines for the management of consolidation in lung cancer screening. BTS guidelines recommend PET-CT for solid nodules ≥300mm³, with a Brock score >10%. At times, consolidation has a nodular or mass-like morphology (figure 1). In this situation, a PET-CT scan may be non-discriminatory as both inflammatory and ma...
Rationale:
Identifying patients with pulmonary fibrosis (PF) at risk of progression can guide management. We explore the utility of combining baseline bronchoalveolar lavage (BAL) and CT in differentiating progressive and non-progressive PF.
Methods:
The derivation cohort consisted of incident cases of PF, for whom BAL was performed as part of d...
In situ pulmonary arterial thrombosis in COVID-19 is not visible on CTPA. However, the presence of CT-measured right heart and pulmonary artery dilatation in COVID-19 is likely attributable to this process and may be a possible surrogate for its detection. https://bit.ly/3g7z5TV.
Background
Large lung nodules (≥15 mm) have the highest risk of malignancy, and may exhibit important differences in phenotypic or clinical characteristics to their smaller counterparts. Existing risk models do not stratify large nodules well. We aimed to develop and validate an integrated segmentation and classification pipeline, incorporating dee...
Objectives
To compare the experience of COVID-protected and mixed cohort pathways in COVID-19 transmission at a tertiary referral hospital for elective CT-guided lung biopsy and ablation during the COVID-19 pandemic.
Methods
From September 2020 to August 2021 patients admitted for elective thoracic intervention were treated at a tertiary hospital...
Purpose
To describe the incidence of pulmonary artery thrombosis in COVID-19 versus influenza pneumonia using CT angiography and to assess whether it may increase the risk of pulmonary hypertension.
Materials and Methods
Single and dual energy CT pulmonary angiography of age- and gender-matched patients with influenza and COVID-19 pneumonia, refer...
Objectives
An increase in lung nodule volume on serial CT may represent true growth or measurement variation. In nodule guidelines, a 25% increase in nodule volume is frequently used to determine that growth has occurred; this is based on previous same-day, test–retest (coffee-break) studies examining metastatic nodules. Whether results from prior...
Objectives:
Severe coronavirus disease 2019 is associated with an extensive pneumonitis and frequent coagulopathy. We sought the true prevalence of thrombotic complications in critically ill patients with severe coronavirus disease 2019 on the ICU, with or without extracorporeal membrane oxygenation.
Design:
We undertook a single-center, retrosp...
Infections of the cardiovascular system may present with nonspecific symptoms, and it is common for patients to undergo multiple investigations to arrive at the diagnosis. Echocardiography is central to the diagnosis of endocarditis and pericarditis. However, cardiac computed tomography (CT) and magnetic resonance imaging also play an additive role...
Increasing bacterial burden in the lower airways of patients with idiopathic pulmonary fibrosis confers an increased risk of disease progression and mortality. However, it remains unclear whether this increased bacterial burden directly influences progression of fibrosis or simply reflects the magnitude of the underlying disease extent or severity....
Background: Mosaic attenuation on CT has been identified in international guidelines as an important diagnostic feature of fibrotic hypersensitivity pneumonitis (FHP) as opposed to idiopathic pulmonary fibrosis (IPF). However, mosaic attenuation (MA) comprises several different radiological signs (low density lobules [LDL], preserved lobules [PL],...
The aim of the pictorial review are to review the HIV manifestations within the gastrointestinal tract. We have detailed five conditions, with reference to the patients' CD4 count - gastrointestinal tuberculosis, Kaposi's sarcoma, small bowel lymphoma, cytomegalovirus colitis and anal carcinoma.
Background The primary objective of primary percutaneous coronary intervention (PPCI) in patients with ST-segment elevation myocardial infarction (STEMI) is to restore epicardial flow and myocardial perfusion in the culprit vessel. It is estimated that up to 65% of the patients presenting with STEMI have multi-vessel disease (MVD), currently it rem...
