Bhavesh Tiwari

Bhavesh Tiwari
Aarti Industries · ADL-API and Custom Synthesis

Ph.D. (Bioanalytical Sciences)

About

30
Publications
197,396
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
170
Citations
Introduction
I am research scholar (Ph.D. in Bioanalytical Sciences) worked as research Fellow for two projects (AYUSH and BRNS) funded by the Government of India. Currently working for a pharmaceutical firm in Analytical Research and Development lab.
Additional affiliations
April 2014 - September 2014
Ramnarain Ruia College
Position
  • Senior Analyst and Project coordinator
Description
  • Government (NMPB, DBT, UGC) and Industry funded (Ajanta Pharma, Neo Pharma, etc) projects; Instrumentation; Standardization of plant extracts/traditional formulations; Safety/pharmacological/pharmacokinetic study; Research papers writing and publication
December 2010 - March 2014
Ramnarain Ruia College
Position
  • SRF BRNS project, DAE, Government of India
Description
  • Instrumentation; Antimycobacterial/immunomodulatory assays; Safety/pharmacokinetic study; Technical/financial aspect of the project; Compilation of the project report and submission to BRNS; Presentations, research papers writing and publication
July 2010 - November 2010
Ramnarain Ruia College
Position
  • JRF/SRF AYUSH project, Government of India
Description
  • Collection of Ayurvedic drugs; Development of SOP of Shadbindu Taila; Technical and financial aspect of the project; Compilation of project report and submission to AYUSH; Presentation at National events, research papers writing and publication
Education
January 2012 - September 2015
Ramnarain Ruia College
Field of study
  • Bioanalytical Sciences
June 2008 - June 2010
Birla College
Field of study
  • Herbal Sciences
June 2003 - June 2006
K.V. Pendharkar College of Arts, Commerce and Science
Field of study
  • Biotechnology

Publications

Publications (30)
Article
The article is a brief review on certain important aspects of tuberculosis. A good number of medicinal plants and their chemical constituents are reported to have antimycobacterial activity comparable to the existing antitubercular drugs or sometimes even better in efficacy. The present review covers the literature published concerning medicinal pl...
Presentation
Full-text available
Basics about genotoxic impurities in pharmaceuticals
Article
Full-text available
Background: Mangifera indica L.; the largest fruit-tree found in India, is an important component of indigenous medical systems. Mangifera indica L. leaves (MIL) have been reported to possess various biological activities and thus, can be a useful source of substances for drug development. Although the leaves have been traditionally used as antibac...
Article
Full-text available
Jawarish‑e‑Amla Sada (JAS); a polyherbal Unani formulation, is claimed as a potential hepatoprotective agent in traditional Unani medicine treatise. Aims and Objectives: Though, JAS has its composition recorded in ancient Unani texts, there have been minimal attempts to scientifically validate its hepatoprotective potential. The present work is an...
Article
Full-text available
Background: Jawarish‑e‑Amla Sada (JAS) is a traditional Unani formulation commonly used for the clinical treatment of Zof‑e‑Meda (weakness of the stomach), Zof‑e‑Kabid (weakness of the liver), Zof‑e‑Qalb (weakness of the heart), Khafqan (palpitation), Nafkh‑e‑Shikam (flatulence in the stomach) and Is‑Hal‑e‑Safrawi (biliary diarrhoea). It is a semis...
Article
Full-text available
Ursolic acid (UA), a hydroxyl pentacyclic triterpenoic acid found in Carissa carandas Linn., a folk medicine used for the treatment of various diseases and also an important component of plant based medicine. In the present work, a precise, accurate and reproducible densitometric HPTLC method is developed and validated in terms of sensitivity, line...
Article
Full-text available
The leaf bud of Ficus benghalensis L. (Moraceae) is commonly known as Vatankur. It is traditionally used in the treatment of diarrhoea, skin disorders, female reproductive disorders and as a hair vitalizer. In the present study macroscopic, microscopic, proximate, phytochemical and safety profile of Vatankur has been evaluated and discussed. Findin...
Article
Full-text available
Urtica dioica L. (Urticaceae, leaves) is commonly used in traditional systems of medicine for the treatment of a wide range of disorders. The present work emphasizes on a validated HPTLC method for estimation of ursolic acid from U. dioica leaves and its available formulation. Chromatographic separation was achieved on silica gel 60 F254 TLC plate...
Article
Full-text available
Marmelosin is one of the major phytochemical constituents of Aegle marmelos (L.) Corr. (Rutaceae). Till date, there are no methods reported for the estimation of marmelosin in plasma matrix using high-performance thin-layer chromatography (HPTLC) which is a versatile analytical technique promoting shorter analysis time and less consumption of solve...
Article
Full-text available
Many plants have been claimed to possess liver protecting activity. But, due to scarcity of potent modern medicine to treat severe liver diseases, many folk remedies of plant origin have been scientifically evaluated for their potential hepatoprotective activity in experimental animal models. Parmelia perlata (Huds.) Ach. (lichen, Parmeliaceae), co...
Article
Full-text available
Vitex negundo L. (Verbenaceae) fruits are reported to possess a wide range of therapeutic properties. The present work is an attempt to evaluate the impact of regional variation on the content of β-sitosterol in V. negundo fruits using validated HPTLC method. Chromatographic separation was achieved on TLC plate pre-coated with silica gel 60 F 254 u...
Article
Full-text available
The physicochemical and phytochemical analysis of medicinal plants is an important quality control tool in medicinal plants research. The present study involves physicochemical and phytochemical evaluation of six different medicinal important plants namely Aegle marmelos (L.) Correa (fruit pulp), Asteracantha longifolia Nees. (seeds), Salmalia mala...
Article
Full-text available
HPTLC and HPLC are two most widely accepted methods for determination of natural products. Present research work envisages microwave assisted extraction of quercetin from hydroethanolic extract of Cuscuta reflexa Roxb. (Cuscutaceae), an unusual parasitic vine. Further, chromatographic characterization of hydroethanolic extract of C. reflexa was car...
Article
Full-text available
Background Infestation with the head louse, Pediculus humanus capitis, is one of the most common parasitic infestations of human worldwide. Traditionally, the main treatment for control of head lice is chemical control that includes wide variety of neurotoxic synthetic insecticides. The main difficulty posed in controlling the head louse infestatio...
Conference Paper
Full-text available
Despite several publications concerning mangrove forests, a clear understanding of the dynamics in mangrove ecosystems is just beginning to emerge. Mangroves have been a source of several bioactive compounds, they have been used in folklore medicines and the extracts have proven activity against human, animal and plant pathogens too. Avicennia mari...
Article
Full-text available
The aim of the current study was to evaluate pharmacognostic characters of leaves of Parkia biglandulosa Wight & Arn. The evaluation was carried out in terms of macroscopic, microscopic, physicochemical, phytochemical and chromatographic analysis.Leaves of P. biglandulosa showed the presence of circular dark brown gland at its base on either side o...
Article
Full-text available
Carissa carandas Linn. is an evergreen, diffuse and spiny shrub grown in different parts of India for its edible fruits. Fruits of C. carandas are used as potential analgesic, anti-inflammatory and anti-diabetic agent. An HPTLC method has been developed and validated for estimation of β-sitosterol content in C. carandas fruits collected from differ...
Article
Full-text available
Shadbindu Taila (ST) is an Ayurvedic formulation used as a remedy for loosening of tooth, weakness of the eyesight, loss of hair, diseases of head, etc., Present study is an attempt to develop some newer approaches for the quality control and standardization of ST. Standardized operating procedure for the preparation of ST was developed in accordan...
Article
Full-text available
Bilvadileha; an Ayurvedic semi-solid formulation, is prescribed for the treatment of digestive impairment, tastelessness, emesis and excessive salivation. Though the formula composition and therapeutic claims of Bilvadileha are part of the Ayurvedic Formulary of India, the scientific methods for its quality and safety evaluation are yet to be docum...
Article
Full-text available
Background: Rhein is the major anthraquinone found in Cassia fistula Linn, which is traditionally used as an important component of plant based medicine. Aims and Objective: To develop and validate -a High Performance Thin Layer Chromatographic method for the estimation of Rhein from C. fistula Linn. Materials and Methods: Chromatographic separatio...
Article
Full-text available
The present work is an attempt to evaluate the impact of regional variation on lupeol content in Carissa carandas Linn. fruits collected from different geographical regions of India using a validated HPTLC method. Chromatographic separation was achieved on TLC plates pre-coated with silica gel 60 F 254 using toluene: methanol (8:1, v/v) as a mobile...
Article
Full-text available
Background: Seeds of Asteracantha longifolia Nees. (Acanthaceae) are an important ingredient in many traditional/herbal formulations used in the management of a wide range of reproductive disorders. They are reported to posses various therapeutically active phytochemical constituents like asteracanthine, lupeol, asterol, β-sitosterol etc. Materials...
Article
Full-text available
Background : Carissa carandas L. (Apocynaceae), an important fruit of tropical and subtropical arid region, has a great potential for the development of a new phytotherapeutic medicine. Due to an increase in commercial products of this fruit in the global market, an extensive phytochemical comparison seems imperative to understand its internal qual...
Article
Full-text available
Background: Psoralea corylifolia L. (Fabaceae, seeds) is used in many formulations for the treatment of a wide range of ailments. Aims and Objective: To develop a reverse phase high-performance liquid chromatography-photodiode array detector (RP-HPLC-DAD) method for quantitation of psoralen from P. corylifolia and its related formulations. Material...
Article
Full-text available
Sufoof -e -Ziabetes -Dulabi (SZD) is an Unani formulation, used for diabetes and renal disorders since ancient times. In the present work, quality of the raw material and the final product SZD was assessed by modern bioanalytical techniques. Quality of the ingredients of SZD was evaluated prior to its preparation. Values of proximate analysis for t...
Article
Full-text available
Jawarish-e-Bisbasa, an Unani polyherbal formulation, is used traditionally in the clinical treatment of stomach ulcers, weakness of digestion, piles, flatulence, nausea, gastritis and as an energy enhancer for stomach. In the current work; phytochemical, safety and pharmacokinetic profile of Jawarish-e-Bisbasa has been evaluated. Phytochemical cons...
Article
Full-text available
Yashtimadhuka Taila (YMT) is an ancient Ayurvedic oil based formulation prescribed for Palita (graying of hair), Keshpatana (falling of hair) and Smasru Patana (falling of beard and moustache). Though YMT is an age old formulation, not much attempt has been made towards its standardization. The current work aims to standardize YMT using modern bioa...
Article
Full-text available
Trikatu Churna (TC) is an ancient traditional Ayurvedic preparation prescribed for a wide range of disorders. Though TC is an age old formulation, there are very few references on its quality control and standardization. In this work, an attempt has been made to standardize TC by qualitatively evaluating the preliminary phytochemicals. Piperine con...
Article
Full-text available
Hingvadi Taila (HT) is an Ayurvedic formulation which is used for Karnashoola (ear-ache) since ancient times. In the present study, the quality of raw materials, intermediates obtained during the preparation of Hingvadi Taila and the final product was assessed by modern scientific procedures. Values of proximate analysis of the raw materials used w...

Questions

Questions (38)
Question
Wanted to analyze nitrobenzene sulfonic acid samples coming from flow reactor for their chromatographic purity and related substances using HPLC.
Question
Want to determine content of D-Arabinose in L-Arabinose using HPLC.
Question
In HPLC why we do not use other ratios? For example, in case of LOQ, why not the ratio of 5, 6, 7, 8, 9 considered?

Network

Cited By

Projects

Project (1)
Project
1. Method for Related sbstances (impurity profiling), Assay, genotoxic impurities, cleaning, quantitative solubility, etc. 2. LC-MS compatible methods, cleaning methods, quantitative solubility, hygroscopic studies, etc.