Betul Rahman

• Doctor of Philosophy
• University of Sharjah

Background Ki-67, a nuclear protein is found in cells undergoing proliferation during the cell cycle. It has been established as an important tumor proliferation and prognostic marker. An increased expression of Ki-67 is observed in inflammation. Periodontitis tissue biopsy specimens have shown Ki-67 expression. Saliva has become popular as a non-i...

Abstract Background Medwakh smoking has radically expanded among youth in the Middle East and around the world. The rising popularity of medwakh/dokha usage is linked to the onset of several chronic illnesses including cardiovascular diseases and cancers. Medwakh smoking is reported to increase the risk of inflammation in the lower respiratory trac...

Aim This in vitro study compared the effect of two commercially available silver diamine fluoride (SDF) products on dentinal tubule (DT) occlusion and dentin permeability. Methods Sixty‐six dentin discs (1.0 mm thick) were divided equally into six groups: acid‐etched with no treatment (negative control—NC), etched and sealed with nail varnish (pos...

Background Various immune mediators have a role in the progression of periodontitis. Placental Growth Factor (PLGF) is important during pregnancy and also is involved in the pathology of several diseases. Hence, this study aimed to evaluate salivary PLGF in health and periodontitis that seemingly has not been reported earlier. Methods Fifty partic...

The study aims to elucidate salivary proteome alterations in medwakh smokers. Saliva samples from 33 medwakh smokers and 30 non-smokers were subjected to proteomic analysis using UHPLC-ESI-QTOF-MS. Saliva samples were analyzed for the production of 13 cytokines using LEGENDplex™ Human Essential Immune Response Panel. Statistical analysis revealed a...

Background Hyaluronic acid (HA) is found in different locations in the periodontium, including mineralized tissues (i.e., cementum and alveolar bone) and non-mineralized tissues (i.e., gingiva and periodontal ligament). In addition, it seems to play an essential part in regulating the underlying mechanisms involved in tissue inflammatory reactions...

Aim The aim of this study was to assess the impact of Nd:YAG laser, glutaraldehyde-based desensitizer (GD), or their combination on occluding dentinal tubules. Materials and methods Fifty dentin samples were obtained from non-carious human third molars and randomly divided into five groups (n = 10): (1) Control group treated with 37% phosphoric ac...

Tobacco smoking affects the microbial ecology of the oral cavity. Smoking can lead to pathogen colonization and ultimately to progression of oral diseases such as periodontitis and caries. The diversity and composition of the supragingival and subgingival plaque microbiota in relation to different types of smoking and oral health have not been inve...

Objectives: Thy-1 (CD90) is a glycosylphosphatidyl-anchored protein belonging to the immunoglobulin family and is known to control mesenchymal stromal cells differentiation into osteoblasts or adipocytes. The study aimed to investigate the salivary levels of Thy-1 in health, periodontitis, obesity, and any potential association. Materials and met...

Modern drug discovery methods led to evolving new agents with significant therapeutic potential. However, their properties, such as solubility and administration-related challenges, may hinder their benefits. Moreover, advances in biotechnology resulted in the development of a new generation of molecules with a short half-life that necessitates fre...

Objective The present study aimed to analyze the salivary levels of macrophage-activating factor (MAF), macrophage-chemotactic factor (MCF), and macrophage migration inhibitory factor (MIF) in healthy and gingivitis patients, and to correlate between the concentrations of these chemo attractants with the intensity of gingival infammation clinically...

Obesity causes gut dysbiosis; nevertheless, little is known about the oral microbiome. We aimed to identify differences in the subgingival microbiota influenced by body weight and periodontal status. Patients (n = 75) recruited at the University Dental Hospital Sharjah, United Arab Emirates, were distributed into three equal groups (healthy weight,...

Objective The present study aimed to analyze the salivary levels of macrophage-activating factor (MAF), macrophage-chemotactic factor (MCF), and macrophage migration inhibitory factor (MIF) in healthy and gingivitis patients, and to correlate between the concentrations of these chemo attractants with the intensity of gingival inflammation clinicall...

The use of alternative tobacco products, particularly medwakh, has expanded among youth in the Middle East and around the world. The present study is conducted to investigate the biochemical and pathophysiological changes caused by medwakh smoking, and to examine the salivary metabolomics profile of medwakh smokers. Saliva samples were collected fr...

Bacterial infections constitute a major challenge of clinical medicine, particularly in specialties such as dermatology and dental medicine. Antiseptics and antibiotics are the main adjunctive therapies to anti-infective procedures in these specialties. However, antibacterial photodynamic therapy (PDT) has been introduced as a novel and promising a...

Objective: This multi-arm, randomized, double-blinded, controlled clinical trial was designed to evaluate the clinical efficacy of 0.5% Green Tea (GT), 0.2 % Chlorhexidine (CHX) and Aloe Vera (AV) mouthwash as compared to the control (CNT) group (scaling and polishing alone with no mouthwash) in the management of dental biofilm induced gingivitis...

Lasers have been found to be effective as an adjunctive in periodontal therapy. The objective of the study was to compare the outcomes of non-surgical adjunctive use of 980-nm diode laser to that of conventional flap surgery in terms of clinical outcome measures and radiographic osseous defect depths. This study was designed as a double-blinded spl...

Peri-implant diseases are frequently presented in patients with dental implants. This category of inflammatory infections includes peri-implant mucositis and peri-implantitis that are primarily caused by the oral bacteria that colonize the implant and the supporting soft and hard tissues. Other factors also contribute to the pathogenesis of peri-im...

This study aimed to assess the effect of smoking different tobacco types on the supragingival microbiome and its relation to dental caries. Forty supragingival plaque samples were collected from smokers of a single tobacco type and non-smokers seeking treatment at the University Dental Hospital Sharjah, UAE. DMFT (decayed, missing and filled teeth)...

This study compared the ability of a calcium silicate-, sodium phosphate-, and fluoride-based (CSSPF) toothpaste (TP) in promoting dentinal tubule occlusion and reducing dentin permeability with that of other commercially available antisensitivity TPs. Seventy-eight dentin discs (1.0±0.1 mm thick) were prepared from the midcoronal area and were tre...

Background: The role of Gram-negative anaerobic periodontal pathogens in periodontal diseases has led to the loss of tooth-supporting structures. These diseases can be prevented by the inhibition of bacterial biofilm on the tooth surfaces. Many treatment modalities have been tried to prevent periodontal diseases. With the rise in resistance to syn...

This study aimed to assess the effect of smoking different tobacco types on the supragingival microbiome and its relation to dental caries. Forty supragingival plaques were collected from smokers of a single tobacco type and non-smokers seeking treatment at the University Dental Hospital Sharjah, UAE. DMFT (decayed, missing and filled teeth) was de...

Abstract Tobacco smoking affects the microbial ecology of the oral cavity. Smoking can lead to pathogen colonization and ultimately to progression of oral diseases such as periodontitis and caries. The diversity and composition of the supragingival plaque microbiota in relation to different types of smoking and oral health have not been investigate...

Tobacco smoking affects the microbial ecology of the oral cavity. Smoking can lead to pathogen colonization and ultimately to progression of oral diseases such as periodontitis and caries. The diversity and composition of the supragingival plaque microbiota in relation to different types of smoking and oral health have not been investigated. The ob...

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Background Candida’s potential association with dental caries has previously been reported in children. This research aimed at investigating the associations between Candida species in whole saliva and dental and periodontal health indices in a sample of adult patients. Methods A cross-sectional study involving 160 patients investigated the associ...

Smoking is a risk factor for periodontal disease, and a cause of oral microbiome dysbiosis. While this has been evaluated for traditional cigarette smoking, there is limited research on the effect of other tobacco types on the oral microbiome. This study investigates subgingival microbiome composition in smokers of different tobacco types and their...

Smoking is a risk factor for periodontal disease, and a cause of oral microbiome dysbiosis. While this has been evaluated for traditional cigarette smoking, there is limited research on the effect of other tobacco types on the oral microbiome. This study investigates subgingival microbiome composition in smokers of different tobacco types and their...

Background: The accumulation and maturation of bacterial plaque at the gingival margin is widely recognized as the primary etiological factor in the development of chronic periodontitis. With the rise in bacterial resistance to antibiotics, there is considerable interest in the development of other classes of antimicrobials for the control of infe...

Background: Nearly a quarter of the population in the UAE has type 2 diabetes mellitus (T2DM), and this medical condition is associated with poorer oral health. The effects on oral health-related quality of life (OHRQoL), however, have not been examined in this population. Therefore, the objective of this study was to assess the impact of oral hea...

Developments in bone regenerative techniques have increased implant placement success in mandible sites previously considered unsuitable for implants. Guided bone regeneration (GBR) procedures preserve tooth sockets immediately after teeth are extracted. GBR can also be applied to regenerate lost bone in defective alveolar ridges before or in conju...

Background: Nearly a quarter of the population in the UAE has type 2 diabetes mellitus (T2DM), and this medical condition is associated with poorer oral health. The effects on oral health-related quality of life (OHRQoL), however, have not been examined in this population. Therefore, the objective of this study was to assess the impact of oral heal...

Background Nearly a quarter of the population in the UAE has type 2 diabetes mellitus (T2DM), and this medical condition is associated with poorer oral health. The effects on oral health-related quality of life (OHRQoL), however, have not been examined in this population. Therefore, the objective of this study was to assess the impact of oral healt...

Objective: The objective of this study was to investigate the opinions of dental students, in one of the dental colleges in the United Arab Emirates (UAE), toward providing tobacco cessation interventions to their patients. Materials and methods: Three-hundred-and-fifty students were administered a questionnaire including questions about tobacco...

Objective The aim of this pilot study is to evaluate to value of primary implant stability for two-piece zirconia implants and longitudinally stability changes of implants during the healing period of 16 weeks. Materials and methods Ten patients treated with 12 two-piece non metallic zirconia dioxide root shape implant (4/10 mm, Axis Biodental, Le...

Assesment of implant stability of zirconium dental implants usung RAF

Assesemnt of implants stability of zirconia implants using RFA

The present study evaluated the gingival condition among school going children in Sharjah, United Arab Emirates and determined its relationship with tooth brushing frequency, diet and dental caries. Four hundred and five children participated in the study. There were 232 boys (57%) and 173 (43%) girls. Children were grouped based on age as ≤6 years...

Our study sought to evaluate the association between periodontitis and body mass index (BMI) among patients with type 2 diabetes mellitus. . In this cross-sectional case control study analysis of 186 diabetic patients, 112 patients had a body mass index ≥30kg/m(2) and 74 control patients had BMI <30kg/m(2). All participants underwent oral examinati...

Objective: The aim of this study was to compare the antiplaque and antigingivitis effects of a mouthwash containing tea tree oil (TTO) with a cetylpyridinium chloride (CPC) mouthwash. Materials and Methods: This was a randomized 4 × 4, controlled, cross-over, involving 20 healthy volunteers in a 5-day plaque re-growth model. Test mouthwashes were...

Objective: the aim of this study was to assess the relationship between BMI and periodontal disease measured by clinical attachment loss (CAL) in an Arab diabetic population. In addition, the association between CAL and diabetes status was also evaluated. Method: In this cross sectional case control study analysis of 186 diabetic patients recruit...

Objective: The purpose of this study was to investigate compliance, awareness and practices of infection control procedures among senior dental students at the College of Dentistry, University of Sharjah, United Arab Emirates. Materials and Methods: The study comprised of 119 subjects of 4th and 5th year dental students. A questionnaire was develo...

The purpose of this study was to assess the knowledge of future dentists of the United Arab Emirates on risk and non-risk factors for oral cancers and correlate it with their own tobacco use, whether they assess their patients' tobacco use and their opinion about the relation of oral cancer and smokeless tobacco use. A total of 270, first- to fifth...

The purpose of this study is to assess the impact of knowledge acquired in preventive aspects of dental education on dental students' own health attitudes, oral hygiene and gingival status in the United Arab Emirates. To compare the self-reported oral health behavior of first year dental students in the University of Sharjah with their actual oral...

Introduction: The benefits of rubber dam in dental practice are well known and it is accepted worldwide as a standard of care. In spite of this, rubber dam use is disregarded by most practicing dentists. The purpose of this study was to assess the use of rubber dam by private practitioners in the United Arab Emirates (UAE) for operative and endodon...

Background: The aim of this study was to determine the differences in oral health attitudes and behavior between second year dental and medical students studying at the University of Sharjah, United Arab Emirates. Methods: The examination was mainly based upon responses to a questionnaire titled “Hiroshima University – Dental Behavioral Inventory (...

Dental caries is a lifetime disease, with highest priority risk group between 11-14 years of age group. Environmental factors such as culture, socioeconomic status, life style and dietary pattern can have a greater impact on caries-resistance or development. The present study was performed to evaluate the relationship between dental caries, oral hy...

Gingival biopsy specimens were obtained from 9 smokers and 7 non-smokers during routine flap surgical procedure to investigate the effects of cigarette smoking on gingival epithelium and connective tissue. Although no remarkable histopathological difference was noted between gingival tissues of smokers and non-smokers, but smokers revealed relative...

The periodontal status of 54 renal transplant recipients and 52 patients with chronic renal failure receiving hemodialysis was evaluated and compared with that of systemically healthy subjects matched for age, sex, social status and the number of teeth present. The renal transplant recipients had been receiving immunosuppressive (IS) drug therapy s...