Beth Jelfs

University of Birmingham

Lesions of COVID-19 can be visualized clearly by chest CT images, therefore, providing valuable evidence for clinicians when making a diagnosis. However, due to the variety of COVID-19 lesions and the complexity of the manual delineation procedure, automatic analysis of lesions with unknown and diverse types from a CT image remains a challenging ta...

Accurate statistical models of neural spike responses can characterize the information carried by neural populations. But the limited samples of spike counts during recording usually result in model overfitting. Besides, current models assume spike counts to be Poisson-distributed, which ignores the fact that many neurons demonstrate over-dispersed...

The focus of this paper is the estimation of a delay between two signals. Such a problem is common in signal processing and particularly challenging when the delay is non-stationary in nature. Our proposed solution is based on an all-pass filter framework comprising of two elements: a time delay is equivalent to all-pass filtering and an all-pass f...

This paper considers the two-dimensional (2D) anchorless localization problem for sensor networks in global positioning system (GPS)-denied environments. We present an efficient method, based on the multidimensional scaling (MDS) algorithm, in order to estimate the positions of the nodes in the network using measurements of the inter-node distances...

Absolute localization of a flying UAV on its own in a global-navigation-satellite-system (GNSS)-denied environment is always a challenge. In this paper, we present a landmark-based approach where a UAV is automatically locked into the landmark scene shown in a georeferenced image via a feedback control loop, which is driven by the output of an aeri...

The focus of this paper is the estimation of a delay between two signals. Such a problem is common in signal processing and particularly challenging when the delay is non-stationary in nature. Our proposed solution is based on an all-pass filter framework comprising of two elements: a time delay is equivalent to all-pass filtering and an all-pass f...

In this paper, we have investigated the differences in the voices of Parkinson’s disease (PD) and age-matched control (CO) subjects when uttering three phonemes using two complexity measures: fractal dimension (FD) and normalised mutual information (NMI). Three sustained phonetic voice recordings, /a/, /u/ and /m/, from 22 CO (mean age = 66.91) and...

This study has investigated the use of inter-personnel mutual information computed from the phonetic sound recordings to differentiate between Parkinson's disease (PD) and control subjects. The normalized mutual information (NMI) denotes the amount of information shared between the voice recordings of people within the same group: PD and Control. T...

Surface electromyography (sEMG) has the potential to provide valuable information regarding the status and health of a muscle. In particular, recent developments in high density sEMG (HD-sEMG), which allow simultaneous recordings from a greater number of electrodes, enable the calculation of muscle attributes such as the conduction velocity of moto...

Surface electromyography (sEMG) has the potential to provide valuable information regarding the status and health of a muscle. In particular, recent developments in high density sEMG (HD-sEMG), which allow simultaneous recordings from a greater number of electrodes, enable the calculation of muscle attributes such as the conduction velocity of moto...

In this study we developed a technique for identifying noisy electrodes in high density surface electromyography (HD-sEMG). The technique finds the spatial similarity of each electrode in the electrode array by counting the number of interactions the electrode has. Using this information the technique identifies noisy electrodes by finding electrod...

Estimation of conduction velocity (CV) is an important task in the analysis of surface electromyography (sEMG). The problem can be framed as estimation of a time-varying delay (TVD) between electrode recordings. In this paper we present an algorithm which incorporates information from multiple electrodes into a single TVD estimation. The algorithm...

Estimation of conduction velocity (CV) is an important task in the analysis of surface electromyography (sEMG). The problem can be framed as estimation of a time-varying delay (TVD) between electrode recordings. In this paper we present an algorithm which incorporates information from multiple electrodes into a single TVD estimation. The algorithm...

This study has developed a technique for identifying the presence of muscle fatigue based on the spatial changes of the normalised mutual information (NMI) between multiple high density surface electromyography (HD-sEMG) channels. Muscle fatigue in the tibialis anterior (TA) during isometric contractions at 40% and 80% maximum voluntary contraction...

Directionality indices can be used as an indicator of the asymmetry in coupling between systems and have found particular application in relation to neurological systems. The directionality index between two systems is a function of measures of information transfer in both directions. Here we illustrate that before inferring the directionality of c...

Hand movement classification based on surface electromyography (sEMG) pattern recognition is a promising approach for upper limb neuroprosthetic control. However, maintaining day-to-day performance is challenged by the non-stationary nature of sEMG in real-life operation. In this study, we propose a self-recalibrating classifier that can be automat...

Fingertip force coordination is crucial to the success of grasp-and-lift tasks. In the development of motor prosthesis for daily applications, the ability to accurately classify the desired grasp-and-lift from multi-channel surface electromyography (sEMG) is essential. In order to extract reliable indicators for fingertip force coordination, we sea...

Vagus nerve stimulation (VNS) can enhance memory and cognitive functions in both rats and humans. Studies have shown that VNS influenced decision-making in epileptic patients. However, the sites of action involved in the cognitive-enhancement are poorly understood. By employing a conscious rat model equipped with vagus nerve cuff electrode, we asse...

There is considerable evidence to suggest early life experiences, such as maternal separation (MS), play a role in the prevalence of emotional dysregulation and cognitive impairment. At the same time, optimal decision making requires functional integrity between the amygdala and anterior cingulate cortex (ACC), and any dysfunction of this system is...

This paper presents an investigation into the cortico-muscular relationship during a grasping task by evaluating the information transfer between EEG and EMG signals. Information transfer was computed via a non-linear model-free measure, transfer entropy (TE). To examine the cross-frequency interaction, TEs were computed after the times series were...

Hand gesture recognition from forearm surface electromyography (sEMG) is an active research field in the development of motor prosthesis. Studies have shown that classification accuracy and efficiency is highly dependent on the features extracted from the EMG. In this paper, we show that EMG spectrograms are a particularly effective feature for dis...

In this letter, a Hierarchical Parametric Empirical Bayes (HPEB) model is proposed to fit spike count data. We have integrated Generalized Linear Models and empirical Bayes theory to simultaneously solve three problems: (1) over-dispersion of spike count values; (2) biased estimation of the maximum likelihood method and (3) difficulty in sampling f...

Patients following prolonged cancer chemotherapy are at high risk of emotional and cognitive deficits. Research indicates that the brain neuronal temporal coding and synaptic long-term potentiation (LTP) are critical in memory and perception. We studied the effects of cisplatin on induction of LTP in the basolateral amygdala (BLA)-anterior cingulat...

Zebrafish larvae display a rapid and characteristic swimming behaviour after abrupt light onset or offset. This light-induced locomotor response (LLR) has been widely used for behavioural research and drug screening. However, the locomotor responses have long been shown to be different between different wild-type (WT) strains. Thus, it is critical...

Time-varying synergies from kinematic data can be used to discern fundamental patterns of movement. We show through simultaneous extraction of synergies from both novice and experienced pianists that movement common to both groups can be identified. The extracted synergies successfully allow for the majority of the variability of the data to be acc...

The rodent anterior cingulate cortex (ACC) is critical for visceral pain and pain- related aversive response in chronic visceral hypersensitive (VH) state. Long-term potentiation (LTP), induced by theta burst stimulation (TBS) in the medial thalamus (MT)-ACC pathway, is blocked in VH rats. However, the neuronal intrinsic firing characteristics and...

Despite being a de facto standard in sparse adaptive filtering, the two most important members of the class of proportionate normalised least mean square (PNLMS) algorithms are introduced empirically. Our aim is to provide a unifying framework for the derivation of PNLMS algorithms and their variants with an adaptive step-size. These include algori...

Noninvasive approaches to measuring cerebral circulation and metabolism are crucial to furthering our understanding of brain function. These approaches also have considerable potential for clinical use "at the bedside". However, a highly nontrivial task and precondition if such methods are to be used routinely is the robust physiological interpreta...

A real-time approach for the identification of second-order noncircularity (improperness) of complex valued signals is introduced. This is achieved based on a convex combination of a standard and widely linear complex adaptive filter, trained by the corresponding complex least mean square (CLMS) and augmented CLMS (ACLMS) algorithms. By providing a...

A novel method for the discrimination between discrete states of brain consciousness is proposed, achieved through examination of nonlinear features within the electroencephalogram (EEG). To allow for real time modes of operation, a collaborative adaptive filtering architecture, using a convex combination of adaptive filters is implemented. The evo...

Responses of NIRS signals in a healthy volunteer are predicted using a model of brain circulation. Optimisation using partial data is shown to increase the model's predictive power which can aid the interpretation of NIRS signals in individuals.

A novel complex echo state network (ESN), utilizing full second-order statistical information in the complex domain, is introduced. This is achieved through the use of the so-called augmented complex statistics, thus making complex ESNs suitable for processing the generality of complex-valued signals, both second-order circular (proper) and noncirc...

A novel method for online tracking of the changes in the nonlinearity within both real-domain and complex–valued signals is introduced. This is achieved by a collaborative adaptive signal processing approach based on a hybrid filter. By tracking the dynamics of the adaptive mixing parameter within the employed hybrid filtering architecture, we show...

A method for extracting information (or knowledge) about the nature of a signal is presented, this is achieved by tracking the dynamics of the mixing parameter within a hybrid filter rather than the actual filter performance. Implementations of the hybrid filter for tracking the nonlinearity and the sparsity of a signal are illustrated and simulati...

Real valued blind source extraction based on a linear predictor is extended to the complex domain using recent advances in complex domain statistics. It is shown that, in general, the mean square prediction error of the algorithm depends both on the covariance matrix and the pseudo-covariance matrix of the source signals. To fully utilise the avail...

A novel hybrid filter combining the complex least mean square (CLMS) and augmented CLMS (ACLMS) algorithms for complex domain adaptive filtering is introduced. The ACLMS has been shown to have improved performance in terms of prediction of non-circular complex data compared to that of the CLMS. By taking advantage of this along with the faster conv...

A novel method for online tracking of the changes in the non- linearity within complex-valued signals is introduced. This is achieved by a collaborative adaptive signal processing approach by means of a hybrid filter. By tracking the dynamics of the adaptive mixing parameter within the employed hybrid filtering architecture, we show that it is poss...

We present a method for extracting information (or knowledge) about the nature of a signal, this is achieved by employing recent developments in signal characterisation for online analysis of the changes in signal modality. We show that it is possible to use the fusion of the outputs of adaptive filters to produce a single collaborative hybrid filt...

A class of algorithms representing a robust variant of the proportionate normalised least-mean-square (PNLMS) algorithm is proposed. To achieve this, adaptive regularisation is introduced within the PNLMS update, with the analysis conducted for both individual and global regularisation factors. The update of the adaptive regularisation parameter is...

unifying approach to the derivation of the class of proportionate normalised least mean square (PNLMS) algorithms is provided. This is an important class of algorithms where the two most used algorithms are introduced empirically. It is shown that it is possible to derive PNLMS algorithms as a result of an optimisation procedure. This is achieved i...

Quantitative performance criteria for the analysis of machine learning architectures and algorithms have been long established. However, the qualitative performance criteria, e.g., nonlinearity assessment, are still emerging. To that end, we employ some recent developments in signal characterisation and derive criteria for the assessment of the cha...

A novel stable and robust algorithm for training of finite impulse response adaptive filters is proposed. This is achieved based on a convex combination of the least mean square (LMS) and a recently proposed generalised normalised gradient descent (GNGD) algorithm. In this way, the desirable fast convergence and stability of GNGD is combined with t...

A novel method for online analysis of the changes in signal modality is proposed. This is achieved by tracking the dynamics of the mixing parameter within a hybrid filter rather than the actual filter performance. An implementation of the proposed hybrid filter using a combination of the Least Mean Square (LMS) and the Generalised Normalised Gradie...