Bert Arnrich

Hasso Plattner Institute · Digital Health – Connected Healthcare

While individuals fail to assess their mental health subjectively in their day-to-day activities, the recent development of consumer-grade wearable devices has enormous potential to monitor daily workload objectively by acquiring physiological signals. Therefore, this work collected consumer-grade physiological signals from twenty-four participants...

Simple Summary Preoperative risk prediction prior to oncologic esophagectomy is crucial for assisting surgeons in accurate patient selection and patients in their informed decision making. A new risk stratification tool, the IESG prediction model, was recently introduced, categorizing patients into different risk levelsMachine learning is a subfiel...

Social media are a critical component of the information ecosystem during public health crises. Understanding the public discourse is essential for effective communication and mis-information mitigation. Computational methods can aid these efforts through online social listening. We combined hierarchical text clustering and sentiment analysis to ex...

Intermittent religious fasting increases the risk of hypo- and hyperglycemia in individuals with diabetes, but its impact on those without diabetes has been poorly investigated. The aim of this preliminary study was to examine the effects of religious Bahá’í fasting (BF) on glycemic control and variability and compare these effects with time-restri...

Intermittent religious fasting increases a risk of hypo- and hyperglycemia in individuals with diabetes, but its impact in those without diabetes is poorly investigated. The study aim was to examine the effects of religious Bahá'í fasting (BF) on glycemic control and variability and compare these effects with time-restricted eating (TRE). In a thre...

Stroke is one of the leading causes of death and disability worldwide, and recovering mobility is an important goal during post-stroke rehabilitation. In this work, we present a study to verify the feasibility of monitoring and visualizing longitudinal stroke gait rehabilitation progress using wearable sensors. Wearable devices such as inertial mea...

Public health institutions rely on the access to social media data to better understand the dynamics and impact of infodemics – an overabundance of information during a disease outbreak, potentially including mis-and disinformation. The scope of the COVID-19 infodemic has led to growing concern in the public health community. The spread of harmful...

Monitoring fatigue during resistance training is essential to avoid injuries caused by overtraining. Fatigue can be comprehensively quantified by the external and internal load, where the external load is the work done by the athlete, and the internal load is the psychological and physiological response to the external load. This paper proposes a c...

Studying individual causal effects of health interventions is important whenever intervention effects are heterogeneous between study participants. Conducting N-of-1 trials, which are single-person randomized controlled trials, is the gold standard for their analysis. As an alternative method, we propose to re-analyze existing population-level stud...

Sensor-based human activity recognition is becoming ever more prevalent. The increasing importance of distinguishing human movements, particularly in healthcare, coincides with the advent of increasingly compact sensors. A complex sequence of individual steps currently characterizes the activity recognition pipeline. It involves separate data colle...

The performance of time-series classification of electroencephalographic data varies strongly across experimental paradigms and study participants. Reasons are task-dependent differences in neuronal processing and seemingly random variations between subjects, amongst others. The effect of data pre-processing techniques to ameliorate these challenge...

Accurate and comprehensive nursing documentation is essential to ensure quality patient care. To streamline this process, we present SONAR, a publicly available dataset of nursing activities recorded using inertial sensors in a nursing home. The dataset includes 14 sensor streams, such as acceleration and angular velocity, and 23 activities recorde...

Objective: To improve performance of medical entity normalization across many languages, especially when fewer language resources are available compared to English. Materials and Methods: We introduce xMEN, a modular system for cross-lingual medical entity normalization, which performs well in both low-and high-resource scenarios. When synonyms in...

This paper proposes a class of algorithms for analyzing event count time series, based on state space modeling and Kalman filtering. While the dynamics of the state space model is kept Gaussian and linear, a nonlinear observation function is chosen. In order to estimate the states, an iterated extended Kalman filter is employed. Positive definitene...

Background The aggregation of a series of N-of-1 trials presents an innovative and efficient study design, as an alternative to traditional randomized clinical trials. Challenges for the statistical analysis arise when there is carry-over or complex dependencies of the treatment effect of interest. Methods In this study, we evaluate and compare me...

In recent years, there has been a growing interest in developing and evaluating gait analysis algorithms based on inertial measurement unit (IMU) data, which has important implications, including sports, assessment of diseases, and rehabilitation. Multi-tasking and physical fatigue are two relevant aspects of daily life gait monitoring, but there i...

Patient monitors at intensive care units produce too many alarms – most of them being unnecessary. Medical staff becomes desensitised and ignores alarms. This phenomenon is called alarm fatigue and it negatively influences for both patients and staff. Some alarms are due to an acute and unforeseeable events but others are the result of a continued...

Psychology and nutritional science research has highlighted the impact of negative emotions and cognitive load on calorie consumption behaviour using subjective questionnaires. Isolated studies in other domains objectively assess cognitive load without considering its effects on eating behaviour. This study aims to explore the potential for develop...

Sensor-based Human Activity Recognition facilitates unobtrusive monitoring of human movements. However, determining the most effective sensor placement for optimal classification performance remains challenging. This paper introduces a novel methodology to resolve this issue, using real-time 2D pose estimations derived from video recordings of targ...

Given the Internet of Things rapid expansion and widespread adoption, it is of great concern to establish secure interaction between devices without worsening the quality of their performance. Using machine learning techniques has been shown to improve detecting anomalous behavior in these types of networks, but their implementation leads to poor p...

Abstract Objective: Fasting states represent a specific metabolic state that follows starvation and is crucial for survival and has been shown to increase longevity and improve health. Trials that research different fasting therapies often rely on self-reported compliance, especially when conducted in an ambulatory setting. Here compliance might di...

Medical applications of machine learning (ML) have experienced a surge in popularity in recent years. The intensive care unit (ICU) is a natural habitat for ML given the abundance of available data from electronic health records. Models have been proposed to address numerous ICU prediction tasks like the early detection of complications. While auth...

Air pollution is the world's deadliest environmental risk factor. Yet there is little effort to educate the public about personal exposure to pollutants such as particulate matter (PM). This paper presents the design and implementation of a portable sensor box (PSB) to collect local, spatially highly resolved particulate matter data. To counteract...

Giving emotional intelligence to machines can facilitate the early detection and prediction of mental diseases and symptoms. Electroencephalography (EEG)-based emotion recognition is widely applied because it measures electrical correlates directly from the brain rather than indirect measurement of other physiological responses initiated by the bra...

A randomized crossover trial was designed to investigate the influence of muscle activation and strength on functional stability/control of the knee joint, to determine whether bilateral imbal‐ ances still occur six months after successful anterior cruciate ligament reconstruction (ACLR), and to analyze whether the use of orthotic devices changes t...

Alarm fatigue, a multi-factorial desensitization of personnel toward alarms, can harm both patients and healthcare staff in intensive care units (ICU). False and non-actionable alarms contribute to this condition. With an increasing number of alarms and more patient data being routinely collected and documented in ICUs, machine learning could help...

Emotions are indicators of affective states and play a significant role in human daily life, behavior, and interactions. Giving emotional intelligence to the machines could, for instance, facilitate early detection and prediction of (mental) diseases and symptoms. Electroencephalography (EEG) -based emotion recognition is being widely applied becau...

The past decade has seen substantial growth in the prevalence and capabilities of wearable devices. For instance, recent human activity recognition (HAR) research has explored using wearable devices in applications such as remote monitoring of patients, detection of gait abnormalities, and cognitive disease identification. However, data collection...

Measuring and adjusting the training load is essential in resistance training, as training overload can increase the risk of injuries. At the same time, too little load does not deliver the desired training effects. Usually, external load is quantified using objective measurements, such as lifted weight distributed across sets and repetitions per e...

Federated learning (FL) is getting increased attention for processing sensitive, distributed datasets common to domains such as healthcare. Instead of directly training classification models on these datasets, recent works have considered training data generators capable of synthesising a new dataset which is not protected by any privacy restrictio...

Purpose: Increasing digitalisation in the medical domain gives rise to large amounts of healthcare data which has the potential to expand clinical knowledge and transform patient care if leveraged through artificial intelligence (AI). Yet, big data and AI oftentimes cannot unlock their full potential at scale, owing to non-standardised data formats...

BACKGROUND Increasing digitalisation in the medical domain gives rise to large amounts of healthcare data which has the potential to expand clinical knowledge and transform patient care if leveraged through artificial intelligence (AI). Yet, big data and AI oftentimes cannot unlock their full potential at scale, owing to non-standardised data forma...

Background: Increasing digitalization in the medical domain gives rise to large amounts of health care data, which has the potential to expand clinical knowledge and transform patient care if leveraged through artificial intelligence (AI). Yet, big data and AI oftentimes cannot unlock their full potential at scale, owing to nonstandardized data fo...

Purpose: Increasing digitalisation in the medical domain gives rise to large amounts of healthcare data which has the potential to expand clinical knowledge and transform patient care if leveraged through artificial intelligence (AI). Yet, big data and AI oftentimes cannot unlock their full potential at scale, owing to non-standardised data formats...

Neural networks have been successfully applied to a wide range of human motion analysis topics in combination with wearable sensor data. However, their computation process is not readily comprehensible. Alternatively, many of the model interpretation efforts do not provide physiologically-relevant insights, thus still limiting their use in clinical...

Studying individual causal effects of health interventions is of interest whenever intervention effects are heterogeneous between study participants. Conducting N-of-1 trials, which are single-person randomized controlled trials, is the gold standard for their analysis. In this study, we propose to re-analyze existing population-level studies as N-...

Background Wearable multi-modal time-series classification applications outperform their best uni-modal counterparts and hold great promise. A modality that directly measures electrical correlates from the brain is electroencephalography. Due to varying noise sources, different key brain regions, key frequency bands, and signal characteristics like...

Patient monitoring technology has been used to guide therapy and alert staff when a vital sign leaves a predefined range in the intensive care unit (ICU) for decades. However, large amounts of technically false or clinically irrelevant alarms provoke alarm fatigue in staff leading to desensitisation towards critical alarms. With this systematic rev...

A bstract The aggregation of a series of N-of-1 trials presents an innovative and efficient study design, as an alternative to traditional randomized clinical trials. Challenges for the statistical analysis arise when there are carry-over effects or confounding of the treatment effect of interest. In this study, we evaluate and compare methods for...

Privacy regulations and the physical distribution of heterogeneous data are often primary concerns for the development of deep learning models in a medical context. This paper evaluates the feasibility of differentially private federated learning for chest X-ray classification as a defense against data privacy attacks. To the best of our knowledge,...

Quantifying neurological disorders from voice is a rapidly growing field of research and holds promise for unobtrusive and large-scale disorder monitoring. The data recording setup and data analysis pipelines are both crucial aspects to effectively obtain relevant information from participants. Therefore, we performed a systematic review to provide...

Privacy regulations and the physical distribution of heterogeneous data are often primary concerns for the development of deep learning models in a medical context. This paper evaluates the feasibility of differentially private federated learning for chest X-ray classification as a defense against privacy attacks on DenseNet121 and ResNet50 network...

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861732/ Abstract: Clinical guidelines integrate latest evidence to support clinical decision-making. As new research findings are published at an increasing rate, it would be helpful to detect when such results disagree with current guideline recommendations. In this work, we describe a software...

To monitor diet, nutritionists employ food journaling approaches, which rely on the subject’s memory. Accordingly, a real-time reminder during eating can help subjects adhere to a journaling routine more strictly. Although previous works used sensors to detect eating activities, no study accounted for the time impact of delivering notifications. Ou...

Observational studies are an important tool for determining whether the findings from controlled experiments can be transferred into scenarios that are closer to subjects’ real-life circumstances. A rigorous approach to observational studies involves collecting data from different sensors to comprehensively capture the situation of the subject. How...

Federated learning allows a group of distributed clients to train a common machine learning model on private data. The exchange of model updates is managed either by a central entity or in a decentralized way, e.g. by a blockchain. However, the strong generalization across all clients makes these approaches unsuited for non-independent and identica...

One of the benefits of Do-it-yourself Artificial Pancreas Systems (DIYAPS) over commercially available systems is the high degree of customization possible through various features developed by the community. This paper investigates the impact of thirteen commonly used custom features on the glycemic outcomes of users with type 1 diabetes. Signific...