Berrin Tezcan

Chelsea and Westminster Hospital NHS Foundation Trust · Obstetrics and Fetal Medicine

Wilm’s tumour, aniridia, genitourinary abnormalities, and mental retardation (WAGR) syndrome is a rare genetic disorder with an estimated prevalence of 1 in 500,000 to 1 million. It is a contiguous gene syndrome due to deletion at chromosome 11p13 in a region containing WT1 and PAX6 genes. Children with WAGR syndrome mostly present in the newborn/i...

Obesity in pregnancy increases health risks for both mother and child during and after pregnancy, but reducing maternal obesity remains a major public health challenge. Evidence for lifestyle interventions resulting in improved pregnancy outcome in obese pregnancies is conflicting. This study aimed to determine the effectiveness of antenatal dietar...

Background Obesity in pregnancy increases health risks for both mother and child during and after pregnancy, but reducing maternal obesity remains a major public health challenge. Evidence for lifestyle interventions resulting in improved pregnancy outcome in obese pregnancies is confl icting. This study aimed to determine the eff ectiveness of ant...

Case Details . We report rare familial unbalanced translocation of chromosomes 7 and 12, which was diagnosed prenatally at 20+3 weeks of gestation. Woman’s partner had been tested in the past and was found to be a carrier of a balanced translocation; his karyotype showed a balanced reciprocal translocation of 46, XY, t(7;12)(q34;q24,32). Partner’s...

Cooling the Cervix below the Body Temperature can Reduce the Risk of Preterm Birth

Evidence has been inconsistent and at times conflicting with little data focusing on how predictive and effective serum alpha-fetoprotein (AFP) and human chorionic gonadotropin (hCG) as a marker of poor pregnancy outcome. In addition, no definite protocol has been developed on how to approach women found to have high level of serum AFP and hCG. The...

The present study aimed to determine the outcome of emergency cerclage depending on clinical presentation. Retrospective analysis of non-elective cerclage divided by clinical presentation: (1) bulging membranes with symptoms (n =19); (2) bulging membranes without symptoms (n =13); (3) asymptomatic ultrasound indicated were cerclage (n =23). Data fr...

Correlation between intrauterine demise (IUD) and social disparity, based on maternal post-code of residence, is assessed in this study in order to find out if there is any correlation between IUD and geographical area. A total of 190 IUD cases from September 2002 to August 2004 were collected retrospectively from the IUD register. The maternity co...

IntroductionFetal fibronectin (fFN) is associated with cervical shortening and membrane exposure, and is used a screening tool for Preterm birth. However its use following rescue cerclage for cervical dilatation and bulging membranes is not well described. The mechanism of action of rescue cerclage is unknown.Methods We performed a retrospective an...

The feasibility of using a mobile text to reach vulnerable patient groups was assessed in this study. A total of 121 pregnant or postnatal women were randomly asked to complete a questionnaire. The questionnaire was given to them in the antenatal clinic, postnatal ward, antenatal ward or in the day assessment unit at St Thomas' Hospital, London. Th...

Accurate noninvasive quantification of volume blood flow in the uterine arteries (UtAs) would have clinical and research benefits. We evaluated the correlation and agreement between uterine artery volume blood flow (UtABF) as calculated (cUtABF) from color/pulsed-wave Doppler acquisitions and that measured (mUtABF) by bilateral perivascular transit...