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Publications
Publications (71)
Das vorliegende Fachbuch liefert detaillierte Einblicke in den Aufbau und die Aufgaben intelligenter und vernetzter Implantate. In Begleitung der Lehrbuchreihe Biomedizinische Technik vermittelt es Grundlagen zur Systemarchitektur vom biokompatiblen Sensorinterface bis zur Mensch-Maschine-Schnittstelle. Einen breiten Raum nimmt die Vorstellung aktu...
The healing process of bone fractures can be monitored by a measurement of the osteosynthesis plate bending. For this purpose a wireless magnetostrictive bending sensor is proposed. A planar rectangular coil on top of a magnetostrictive Galfenol (${\hbox {Fe}}_{83}{\hbox {Ga}}_{17}$ alloy) layer forms an electrical resonant circuit. The sensor is m...
Pertrochanteric fractures are a rising major health-care problem in the elderly and their operative stabilisation techniques are still under discussion. Furthermore, complications like cut-out are reported to be high and implant failure often is associated with poor bone quality. The PFNA(®) with perforated blade offers a possibility for standardis...
Zusammenfassung
Es wird ein Experimentalaufbau zur Anregung und drahtlosen Messung von Schwingungen einer teilweise in einen künstlichen Oberschenkelknochen einzementierten Hüftprothese vorgestellt. Um das dynamische Verhalten des mechanischen Systems zu diskutieren, wurde ein translatorisch-rotatorisches Netzwerkmodell erstellt. Mit diesem Modell...
The healing process of bone fractures can be monitored by a measurement of the osteosynthesis plate bending. An electrical resonant circuit consisting of a coil with a magnetostrictive Galfenol core and a capacitance enables an indirect wireless measurement of the plate bending. The Galfenol core is manufactured with a thin film technology using a...
A new solution for the integration of a wireless measurement system intended for the detection of hip prosthesis loosening by vibration analysis is presented. Small vibration amplitudes in the presence of noisy sensor signals of the excited prosthesis are measured with a digital lock-in amplifier which is integrated in the prosthesis together with...
Using a cadaver model and multiple continuous compartment pressure measurement, we sought to determine the pressure distribution in different osseofascial spaces of the foot and determine the quickest and most effective technique of pressure release.
The compartment pressures were measured (in mmHg) in five different osseofascial spaces of each foo...
Nutzen, Qualität und Kosten medizinisch-therapeutischer Verfahren stehen zunehmend im Interesse entscheidungsverantwortlicher Akteure im Gesundheitswesen. Um diese Determinanten zu optimieren, werden verstärkt auch die Möglichkeiten der Telemedizin mit ihren elektronischen und bildgebenden Innovationen genutzt. Telemedizin umfasst dabei die Nutzung...
Die Langlebigkeit von Hüftendoprothesen ist v. a. durch die aseptische Lockerung begrenzt. Ziel dieser Arbeit war der Aufbau eines digitalen Systems zur Erfassung von Schaftlockerungen von Hüftendoprothesen. 4 identische Prothesenschäfte wurden mit jeweils 3 2-achsigen Beschleunigungssensoren versehen und in künstliche Femora eingebracht. Zur Simul...
Technologies in telecommunication and information are being increasingly applied in the public health system of the western world. Also responsible for this development is the cost factor in the field of financing and maintenance of such a system of superior medical supply, as well as the concurrent patient' demand for optimized medical "24 h care...
Technologies in telecommunication and information are being increasingly applied in the public health system of the western world. Also responsible for this development is the cost factor in the field of financing and maintenance of such a system of superior medical supply, as well as the concurrent patient’ demand for optimized medical “24 h care...
The televisite is a form of application of telemedicine, that allows a communication between the patient and the family doctor or specialist in the clinic after discharging of hospital. Pioneers for the use of telematic projects have been up to now wide states like the USA, Canada, Norway or Australia to provide, guarantee and maintain by the means...
In der minimal invasiven Diagnostik, Therapie und Therapiekontrolle, bei Implantaten oder Medikamentdosiersystemen sind heute mikro- und nanotechnologische Komponenten wesentliche Bausteine von Gesamtsystemen. Aktuelle Entwicklungen zeigen ein weites Feld von Einsatzmöglichkeiten der Mikro- und Nanotechnik für medizinische Anwendungen. Allein der W...
In cases of extended post-traumatic soft-tissue and bone loss as well as with mutilating infection or radical tumor resection, multidisciplinary options are required to salvage extremities and functional rehabilitation. A surgical team approach allows for reduction of amputation rates, wound healing complications, and secondary procedures in limb o...
Ausgedehnte posttraumatische Knochen- und Weichteildefekte, mutilierende Infektionen und Tumorresektionen erfordern den Einsatz multidisziplinärer Konzepte zum Extremitätenerhalt und zur funktionellen Rehabilitation. Die Bündelung von Spezialkenntnissen führt bei diesen Indikationen zur Verminderung von Amputationsraten, Wundheilungsstörungen und K...
Ziel der vorliegenden biomechanischen Untersuchung war es, die funktionelle Bedeutung der Syndesmosen und des Deltabandes im Zusammenhang mit einer Knöchelfraktur vom Typ Weber B zu überprüfen. In einer speziellen Halterung wurden 12 Unterschenkel-Fuß-Präparate in Neutralstellung getestet. Gemessen wurde die isolierte Taluslateralverschiebung in mm...
The idea of Televisite is to equip the patients with a camera and a communication panel at the time of their discharge from the hospital. In that way patients and physicians are able to continue the treatment and the rehabilitation program. An easy to handle interface helps the patient to answer simple questions or to send voice recordings, picture...
The TELTRA Televisite is a remote patient monitoring system, allowing the patient to remain at home and deliver monitoring data, images, speech and video recordings to the doctor. From this point, all the above mentioned sources of information will be referred to as data. As a medium for the information transfer, the Televisite uses ISDN or multi-c...
The Televisite application is a post-stationary consulting method, whose main aim is to reduce the treatment time of inpatients. It provides a high quality home consultation after the patient has been discharged from the hospital. The technical handling and the validity of the new method of caring will be analysed--particularly the human-machine in...
Durch ein Televisite zur poststationären Betreuung sollen stationäre Behandlungszeiten verkürzt und Patienten häuslich auf qualitativ hohem Niveau betreut werden. Analysiert wird das technische Handling und die Validität dieser noch neuen Betreuungsform, insbesondere das Maschine-Mensch-Interface. Patienten und Methoden: In einer prospektiven Pilot...
Für den Bereich der Onkologie fängt die Zukunft gerade erst an. Mit Biochips wird man in Zukunft innerhalb weniger Minuten
DNA-Sequenzen oder Proteine messen können, was eine intraoperative Beurteilung von Gewebe wie Resektionsränder und Lymphknoten
erlauben kann.
This paper presents a micro-movement long-term monitoring system optimising the healing process of fractures. It focus in particular on the energy and data transmission path of the system. Continuous and accurate monitoring near the fracture zone of bones requires an implantable and low power consumption device. Additionally, the implant needs to b...
Femoral neck fractures are frequent fractures of the elderly. They can be treated by the use of dynamic hip screws, lag screws, bipolar hemi-protheses or total hip replacement. The results are markedly influenced by the timing of the operation and the choice of the implant. Using the Garden classification of femoral neck fracture we demonstrate a d...
Schenkelhalsbrüche zählen zu den häufigsten Verletzungen des alten Menschen und werden oft mit der DHS einer Verschraubung
oder Teil- oder Totalendoprothesen versorgt. Neben der Wahl des richtigen Operationszeitpunktes liegt der Schwerpunkt einer
suffizienten Versorgung in der Auswahl des adäquaten Operationsverfahrens. Ziel dieser Arbeit ist es an...
Femoral neck fractures are frequent fractures of the elderly. They can be treated by the use of dynamic hip screws, lag screws, bipolar hemiprotheses or total hip replacement. The results are markedly influenced by the timing of the operation and the choice of the implant. Using the Garden classification of femoral neck fracture we demonstrate a di...
A new, highly miniaturized hybrid integrated solution for
telemetric pressure measurement in biomedical applications is presented.
The telemetrically powered ITES (Implantable Telemetric Endo-System)
consists of a surface micro-machined capacitive type absolute pressure
sensor fabricated in an eight-mask MOS-like process and two low-power
ASICs for...
The development of a low-g accelerometer for the use in medical
applications is presented. Commercial available accelerometers fulfill
the required specifications in terms of resolution using closed-loop
operation. Due to the high energy consumption in closed-loop operation,
these sensors are not suitable in implantable devices. New technologies
en...
The results we presented are a part of the running project DOMFRA (Dosed Microstimulation of Fracture Zones) within the framework of the “Applicationoriented research and development in University of Applied Sciences” funded by the Federal Ministry of Research (BMBF). Up to now, medical researches have only introduced micro movements in tests on an...
Approximately 40,000 trochanteric femur fractues have to be expected in Germany yearly. The incidence is increasing. As a typical fracture type of the elder patient here the posttraumatic loss of life or of personal independence has to be suspected and in former times frequently took place. Whereas in the 70s up to 19 different competitive techniqu...
A new low power integrated pressure sensor system with digital output (1 bit PDM signal) for medical applications is presented. The absolute pressure sensor comprising 400 nm thick surface micromachined polysilicon membranes for capacitive pressure detection and a monolithic integrated 2nd order sigma–delta-modulator including voltage reference and...
Patients with severe trauma or polytrauma frequently acquire alterations in immune functions which are correlated to dysbalanced cytokine synthesis. In these settings the role of polymorphonuclear neutrophil granulocytes (PMN) as cytokine-producing cells is less well characterized. The immunosuppressive role of interleukin (IL)-10 is well known, an...
A different biomechanical environment markedly modulates the mechanical characteristics of fracture repair. In this study we compared a plate osteosynthesis with a limited wave plate osteosynthesis in the sheep tibia (n = 5). Callus formation and the potential of fracture repair were markedly enhanced when the limited wave plate was used.
Im Gegensatz zu einer allzu rigiden Bruchstabilisierung werden heute mehr dynamische Fixationsverfahren verwendet, welche Mikrobewegungen zulassen und die Knochenbruchheilung via Kallogenese fördern [1–7]. Durch eine Wellenplatte definierter Vorbiegung können Mikrobewegungen kontrolliert werden. Während über-brückende Plattenosteosynthesen von Mehr...
Between 1984 and 1994, 40 patients with a posttraumatic compartment syndrome of the lower leg and foot were treated for talipes equinovarus adductus foot deformity, which subsequently developed. Twenty patients had a wedge osteotomy followed by arthrodesis of the midtarsal joint (Chopart joint). Another 17 patients had an arthrodesis of the midtara...
Acute Achilles tendon ruptures are mostly related to recreational activities. Therefore, these patients intend to return to sports as soon as possible with no functional deficiency. This is the first study, comparing functional results after functional treatment to those after surgery. According to sonographic examinations of the tendon gap, primar...
1. The perivascular nerves of isolated tail arteries from Wistar rats were stimulated with field pulses (1 Hz, 2 pulses, every 2 min). omega-Conotoxin 10 nmol l-1 depressed neurogenically mediated contractions, but did not influence the contractions to noradrenaline 0.1-0.3 mumol l-1. 2. The inhibitory effect of omega-conotoxin was concentration-de...
An experimental setup for excitation of hip prosthesis vibrations intended for the detection of prosthesis loosing is developed and analyzed Stand-alone measurements were taken at an artificial thigh where an electrodynamic audio shaker was fixed at the knee using an appropriate designed support structure It could be demonstrated that the measureme...