About
144
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Introduction
Current institution
Additional affiliations
October 1986 - September 1999
University Kiel, Germany
Position
- Group Leader
August 1981 - August 1986
University Hospital Hamburg
Position
- postgraduate Position
October 1999 - present
Position
- full time professor for Clinical Psychology,
Description
- Expertise: Clinical Biopsychology, Spatial Cognition, Remote Memory, Basalganglia and related disorders, Neurodegeneration, Behavior Analysis and Intervention, Behavioral Medicine
Publications
Publications (144)
Background
Vestibular schwannoma (VS) often results in persistent dizziness that negatively impacts quality of life (QoL). While physical effects are well-documented, the influence of psychological factors on dizziness severity is less studied. This study investigates how psychological characteristics affect dizziness in VS patients.
Methods
In thi...
BACKGROUND
This study aimed to investigate the connection between psychological factors and postoperative tinnitus in vestibular schwannoma (VS) patients following retrosigmoid microsurgery.
MATERIAL AND METHODS
Ninety-three VS patients participated, completing questionnaires on demographics, tinnitus severity (THI-12), personality traits (TIPI-G)...
Background
Current treatment in Alzheimer’s disease (AD) is initiated at a stage where the brain already has irreversible structural deteriorations. Therefore, the concept of treatment prior to obvious cognitive deficits has become widely accepted, and simple biochemical tests to discriminate normal aging from prodromal or demented stages are now c...
Objective: This study aimed to investigate the connection between psychological factors and postopera-tive tinnitus in vestibular schwannoma (VS) patients following retrosigmoid microsurgery. Design: Cross-sectional study. Study sample: Ninety-three VS patients participated, completing questionnaires on demographics, tinnitus severity (THI-12), per...
Postoperative headaches (POHs) following retrosigmoid microsurgery for vestibular schwannoma (VS) can significantly impact patients’ perceived health benefits (PHBs). In this cross-sectional observational study, 101 VS patients were investigated. For the assessment of pain, the Rostock Headache Compendium (RoKoKo) and the German pain processing que...
Postoperative headaches (POH) following retrosigmoid microsurgery for ves-tibular schwannoma (VS) can significantly diminish patients' perceived health benefits (PHB). A survey of 101 VS patients, utilizing the Rostock Headache Compendium, Glasgow Benefit Inventory, Ten-Item Personality Inventory (TI-PI-G), and German pain processing questionnaire...
Background: Associations between premorbid psychological factors and postoperative headache (POH) after microsurgical treatment via the retrosigmoid approach for vestibular schwannoma (VS) were investigated in this retrospective single-center study. A total of 101 VS patients completed the Rostock headache questionnaire (RoKoKo), the hospital and a...
Impulse control disorders (ICD) in Parkinson’s disease (PD) frequently occur, not always as a direct consequence of dopaminergic medication. This study investigated premorbid personality traits and behavioural characteristics in non-demented PD patients with self-reported symptoms of ICD (PD-srICD). From a total of 200 non-demented PD patients who...
Abstract
Objective: Investigate associations between premorbid psychological factors and postoperative headache (POH) after microsurgical treatment of vestibular schwannoma (VS).
Methods: In a single-center and online study, 112 VS-patients completed a short self-assessed questionnaire, the Rostock Headache Questionnaire (RoKoKo), the Hospital a...
In diesem Band werden zunächst Klinik, Ätiologie und ein somatisch-neuropsychologisches Störungsmodell des idiopathischen Parkinson-Syndroms erläutert. Neben der Parkinson-Demenz und den vielfältigen anderen kognitiven Besonderheiten werden zudem parkinson-typische psychische Beschwerden und Störungen wie Depression, Angst und Impulskontrollstörung...
On a group level, satisfaction with botulinum neurotoxin (BoNT) treatment in neurological indications is high. However, it is well known that a relevant amount of patients may not respond as expected. The aim of this study is to evaluate the BoNT treatment outcome on an individual level using a statistical single-case analysis as an adjunct to trad...
Zusammenfassung: Die angewandte Neuropsychologie bietet für vielfältige Berufsfelder außerhalb der Heilkunde gemäß Psychotherapiegesetz zahlreiche Ansatzpunkte. Neben Aufgaben in der Begleit- und Evaluationsforschung und der Aus- und Weiterbildung können zahlreiche nichttherapeutische Anwendungsgebiete identifiziert werden. Neuropsychologisches Wis...
ZUSAMMENFASSUNG
Mit diesem Artikel wird die besondere Belastungssituation der Angehörigen von Parkinson-Patienten mit ihren entsprechenden Interaktionsproblemen dargestellt und auf die psychischen bzw. psychosomatischen Folgen eingegangen, die diese sekundär entwickeln können. Des Weiteren werden typische „Angehörigen-Charaktere“ beschrieben und ei...
Background
Subjective symptom complaints often do not match the expert’s ratings in focal dystonia. Nonetheless, perceived symptom intensities drive compliance and outcome of botulinum neurotoxin (BoNT) treatment.
Methods
Perception of symptom development across a BoNT cycle was obtained in 21 cervical dystonia (CD) and 15 hemifacial spasm (HFS) p...
Purpose
The aim of the study was to develop an optimally designed and comprehensibly formulated patient information leaflet (PIL) to improve patients’ memory of information provided by physicians during a radiotherapy (head and neck area) consultation. This PIL was tested on unaffected probands for its usefulness in clinical practice.
Patients and...
Purpose
A patient information leaflet (PIL) on oral and dental care during radiotherapy was tested whether and at which time during therapy it would be helpful to increase the knowledge about the therapy and the resulting side effects and the management of these. Additionally, the participants’ subjective perception of being well informed about the...
Background:
In the past decades, behavioral medicine has attained global recognition. Due to its global reach, a critical need has emerged to consider whether the original definition of behavioral medicine is still valid, comprehensive, and inclusive, and to reconsider the main tasks and goals of the International Society of Behavioral Medicine (I...
Die deutsche Version des SCOPA-Sleep Fragebogens zum Download
Aim of the study was the cross-cultural adaptation and validation of the German version of the Scale for Outcomes in Parkinson’s disease-Sleep Scale (SCOPA-Sleep) for assessment of night-time sleep problems (NS) and daytime sleepiness (DS). Eighty-three patients with Parkinson’s disease completed the SCOPA-Sleep and a multitude of measures for asse...
Objectives:
The main focus of revious research into coing with breast cancer, have been mostly with regards to the negative imacts such as emotional stress, anxiety, deression or cognitive dysfunction. However, atients also reort ositive changes that have come about as a result of their struggle with cancer. This is referred to as osttraumatic grow...
Background
Differential effects of botulinum toxin (BoNT) treatment in cervical dystonia (CD) and blepharospasm (BSP) treatment satisfaction and emotional responses to a life with a disabling condition were investigated. Special interest was drawn to the course within a BoNT treatment cycle and the effects of subjective well-being vs perceived inte...
To document specific learning mechanisms in patients with Parkinson's disease (PD) with and without impulse control disorder (ICD). Thirty-two PD patients receiving dopamine replacement therapy (DRT) were investigated. Sixteen were diagnosed with ICD (ICD (+) ) and 16 PD patients matched for levodopa equivalence dosage, and DRT duration and severit...
Performance in the Morris water maze has been widely used in routine behavioural studies of rodents. Since the advent of computer-based virtual environments, adaptations of the water maze have become available for human research. Despite decades of comparative neuroscience, formal comparisons of human and animal place navigation performance are rar...
Behavioral medicine focuses on the patient's self-regulation. Thus, behavioral interventions are essential in many domains of medicine. For both patients and their caregivers, coping with the disease and emotional disorders are major challenges. With respect to Parkinson's disease, nonmotor symptoms are as important as motor symptoms. Behavioral fa...
To document satisfaction of Botulinum toxin (BoNT) treatment in cervical dystonia and blepharospasm, 497 patients with long standing dystonia (372 ST, 125 BP) were investigated with respect to perceived intensity of motor symptoms, characteristics of the dystonia, treatment variables, treatment satisfaction especially within the course of BoNT cycl...
Zusammenfassung
Im Rahmen einer multizentrischen Patientenund Arztbefragung wurden 497 Patienten mit zervikaler Dystonie (n = 372) und Blepharospasmus (n = 125) in Bezug auf die Zufriedenheit mit der Botulinumtoxin-Therapie (BoNT) befragt. Zusätzlich wurden krankheits- und behandlungsbezogene Angaben, Einstufungen zur Lebensqualität, der berufliche...
Background:
Several MRI studies have demonstrated hippocampal atrophy in Parkinson's disease (PD), a structure considered a key element in spatial learning. Despite this, no study has been undertaken to investigate spatial navigation in PD using a virtual version of the Morris water maze, which is the gold standard for testing hippocampal function...
Der Anteil Älterer steigt in unseren Gesellschaften kontinuierlich an. Entsprechend kommt es zu einer stetigen Zunahme der von einer akuten oder degenerativen neurologischen Krankheit Betroffenen. Gerade bei diesen Erkrankungen stehen den Patienten jedoch bereits heute eine Vielzahl von Methoden zur Verfügung, mit denen sie selbst Einfluss auf das...
Introduction:
It is generally accepted that estrogens play a protective role in cognitive function. Therefore, it can be expected that subtotal estrogen deprivation following aromatase inhibition will alter cognitive performance.
Methods:
In a cross-sectional study we investigated 80 postmenopausal women with breast cancer. Memory and spatial co...
Tierexperimentelle Studien an Mäusen belegen, dass eine kombinierte Radiochemotherapie (RCX ) die adulte hippocampale Neurogenese hemmt und mit einer Beeinträchtigung des räumlichen Gedächtnisses einhergeht. Ziel der vorliegenden Untersuchungen auf der Basis von in-vivo 1H-MR-Spektroskopie-Messungen in ausgewählten Hirnregionen und parallel dazu du...
Background
Neuronal plasticity leading to evolving reorganization of the neuronal network during entire lifespan plays an important role for brain function especially memory performance. Adult neurogenesis occurring in the dentate gyrus of the hippocampus represents the maximal way of network reorganization. Brain radio-chemotherapy strongly inhibi...
Fünf Monate vor dem hausärztlichen Erstkontakt bemerkte eine 48-jährige Büroangestellte eines Morgens einen ziehenden Schmerz im Halsbereich. Es fühlte sich zunächst wie ein „steifer Hals“ an. Seit einigen Wochen persistieren diese Beschwerden mit variierender Intensität und langsam ansteigender Zugspannung nach hinten rechts. Eine Drehbewegung nac...
Deterioration in spatial memory with normal ageing is well accepted. Animal research has shown spatial reversal learning to be most vulnerable to pathological changes in the brain, but this has never been tested in humans. We studied ninety participants (52% females, 20-80 yrs) in a virtual water maze with a reversal learning procedure. Neuropsycho...
Verhaltensmedizinische Interventionen setzen bei neurologischen Erkrankungen mit dem Ziel an, die gesellschaftliche Teilhabe so weit wie möglich zu erhalten oder wiederherzustellen. Dies kann über restitutive und kompensatorische Zugangswege mit oder ohne direkte Intervention am somatischen Substrat erfolgen. So lassen sich schlaganfallbedingte Par...
Bei der dopaminergen Therapie beim Morbus Parkinson entwickeln einige Patienten Verhaltensauffälligkeiten, die bislang als Impulskontrollstörungen (IKS) deklariert werden. Diese haben für die Betroffenen oft schwerwiegender soziale, psychische und physische Konsequenzen und werden zudem aufgrund der heiklen Thematik eher selten spontan berichtet. B...
Parkinsonpatienten (PD) werden zur Linderung ihrer
motorischen Symptome häufig mit Dopaminagonisten
behandelt. Diese führen bei ca. sechs Prozent aller
PD-Patienten und bei ca. 13% aller dopaminagonistisch
behandelten Fälle zu selbst- und fremdschädigenden
Zuständen compulsiven Spielens, Kaufens, Essens und
Sexualverhaltens. Diese Störungen persist...
BACKGROUND:
Spasmodic torticollis patients were investigated with respect to the number of adjunct treatments used before and after the introduction of botulinum toxin therapy (Btx). The study was designed in a similar way to an earlier investigation by Birner et al. (Nervenarzt 70:903-908, 1999).
MATERIAL AND METHODS:
A total of 247 patients with...
Figural fluency refers to the ability to internally generate appropriate non-verbal behaviour. Whereas deficits in verbal fluency rank among the most prominent cognitive sequelae in Parkinson's disease (PD), little is known about figural fluency and its assessment in PD. This is the first comprehensive comparison of the psychometric properties of f...
In addition to the motor symptoms of Morbus Parkinson, a number of cognitive and emotional changes take place. The diagnosis of these concomitant symptoms has received increasing attention in research and clinical practice. Global rating scales offer economical advantages but generally do not satisfy the requirements of psychometric criteria, and t...
Wegen ihrer psychophysiologischen und emotionalen Besonderheiten standen die Primären Dystonien viele Jahrzehnte lang im Spannungsfeld unterschiedlichster medizinischer und psychologischer Ätiologievorstellungen und Therapiestrategien. Inzwischen ist klar, dass es sich um Erkrankungen der Basalganglien handelt, deren Pathophysiologie weit über die...
De ziekte van Parkinson is een van de meest voorkomende aandoeningen van het zenuwstelsel. Vanwege cognitieve stoornissen, dementie en symptomen als angst, depressie en apathie wordt er bij de behandeling steeds vaker een beroep gedaan op (neuro)psychologen. In Ziekte van Parkinson beschrijven Duits en Leplow de diagnostiek en behandeling, waarbij...
Objective
To validate the DEpression Screening in PARkinson’s disease (DESPAR) self-administered questionnaire, a subscale of a recently developed new screening tool for secondary depression.Background
Although depression has a high prevalence in PD, it often remains undetected. Currently, the Beck Depression Inventory (BDI-1A) is the gold standard...
Background: Adjuvant endocrine therapy is the mainstay in the therapy of primary breast cancer. However, the impact of endocrine therapy on cognitive function in patients with breast cancer is still unclear. Numerous studies suggest a protective effect of estrogens on neurons. From these findings it has been derived that the almost complete estroge...
Eine 32-jährige Hausfrau fühlt sich vor jedem Verlassen der Wohnung gezwungen, alle elektrischen Geräte, Fenster, Türen und
Wasserhähne kontrollieren zu müssen. Dieses erfolgt in genau festgelegter Abfolge: erst die vier Herdschalter (jeden einzeln
fixieren und halblaut jeweils langsam und konzentriert „aus-aus-aus!“ sagen), dann die Kaffeemaschine...
A critical role in place learning has been attributed to place cells within the cornu ammonis 1 (CA1) sector of the hippocampus
in rodents. The role of CA1 cells in the human hippocampus with regard to place learning remains elusive. Using a virtual
Morris water maze, we investigated patients with acute transient global amnesia (TGA), a rare self-l...
The study examined the age and sex effects in spatial learning and mental rotation in 58 adults. We developed two new spatial learning tasks using virtual reality (VR): a navigation task and a pointing task. The results show that younger adults outperformed older adults in both virtual tasks but not in mental rotation. Males outperformed females in...
Efficacy of botulinum treatment depends on its regular administration. Therefore, compliance was investigated in spasmodic torticollis patients undergoing botulinum toxin therapy. Thirty-seven patients were studied with respect to the course of disease, timing of botulinum treatment, subjective symptom intensity, depression, and disease specific an...
Zusammenfassung
Hintergrund: Da die Wirksamkeit einer Botulinumtoxintherapie von der Regelmäßigkeit ihrer Anwendung abhängt, wurde eine Erhebung zu Therapietreue an 37 Patienten mit idiopathischem Torticollis spasmodicus durchgeführt. Methode: Grafische Darstellung des Erkrankungsverlaufes, schriftliche Erfassung von Beginn und Häufigkeit der Botul...
Although human spatial cognition is at the focus of intense research efforts, experimental evidence on how search strategies differ among age and gender groups remains elusive. To address this problem, we investigated the interaction between age, sex, and strategy usage within a novel virtual water maze-like procedure (VWM). We studied 28 young adu...
Ziel dieses verhaltenstherapeutischen Trainings ist es, sozial unsicheren Kindern mehr Selbstbewusstsein zu vermitteln, Vermeidungstendenzen abzubauen, neue praktische Handlungsstrategien aufzubauen und den Einsatz vorhandener Kompetenzen in sozialen Situationen zu fördern. Das Training ist für Jungen und Mädchen im Alter zwischen fünf und zehn Jah...
Though strategic deficits are extensively investigated in Parkinson's disease (PD), little is known about the effects of instruction for PD patients. Thus, we compared the ability to internally generate a cognitive strategy with the ability to use a strategy after elaborate strategy instruction.
Patients with PD (n=14) and matched healthy controls...
The availability of alternative sources of information, e. g. the internet, may influence the quantity and quality of information cancer patients receive regarding their disease and treatment. The purpose of the present study was to assess perception of information in cancer patients during radiotherapy as well as media preferences and specifically...
Many patients with breast cancer complain about concentration and memory problems in connection with systemic therapy. A number of studies investigating the possible decrease in cognitive abilities were published in the 1980s. Numerous studies showed impaired performance of patients receiving chemotherapy. The results concerning profile, extent, an...
This editorial provides reasons for the restructuring of Zeitschrift für Psychologie/Journal of Psychology (ZfP/JoP), the second oldest psychology journal in the world, from this issue onwards. The journal will continue to consist entirely of topical issues. Each will now generally start with a Review Article or an Editorial covering the major aspe...
Das erfolgreiche Trainingsprogramm liegt nun in einer erweiterten Auflage vor, welche nun auch das Vorgehen beim Tiger-Training im Einzelsetting erläutert. Alle Materialien sind zusätzlich auf einer CD-ROM verfügbar.
Ziel dieses verhaltenstherapeutischen Trainings ist es, sozial unsicheren Kindern mehr Selbstbewusstsein zu vermitteln, Vermeidungst...
Effective coping of severe neurological disease can be disturbed by means of various psychological factors. Adaptive disorders, secondary depression, coping habits and the interaction of psychological factors and neurological symptoms predict the clinical status more than the degree of disability. Proprioception and learning also modulate the emoti...
Zusammenfassung
Eine langfristig günstige Krankheitsbewältigung kann durch eine Vielzahl psychologischer Mechanismen gestört werden. Neben der Entwicklung von Anpassungsstörungen oder sekundären psychischen Störungen kann eine komplizierte Interaktion aus Verhaltensfaktoren und neurologischer Symptomatik die Krankheitsentwicklung in deutlich größer...
Deep brain stimulation (DBS) has gained increasing attention as a therapy for movement disorders. Neuropsychological alterations can accompany the disease evolution and medical therapy of PD. Also, interfering abruptly with the biological balance by means of a surgical intervention into complex circuits with motor but also cognitive and limbic func...
A psychological survey was conducted at the Wittlinger Therapy Center, a lymphedema clinic, to determine possible differences between patients with lymphedema and healthy people (without lymphedema). We investigated how the absence or presence of lymphedema affects patients' quality of life and mental state, and how these two different groups manag...
Zusammenfassung: Ein erheblicher Anteil an Patienten mit einer idiopathischen Parkinson-Erkrankung (PD) entwickelt im Verlauf eine sekundäre Depression. Die Prävalenzraten schwanken erheblich, da die Diagnosestellung aufgrund von Symptomüberschneidungen zwischen neurologischer Grunderkrankung und Major Depression (MD) erschwert ist. Dies führt zu P...
In der Kategorie F54 der ICD-10 werden „Psychosomatische Erkrankungen“ codiert, die für sich allein keine abgegrenzte diagnostische
Einheit darstellen. Stattdessen können sich psychosomatische Faktoren bei der weit überwiegenden Mehrheit aller medizinischen
Zustände ergeben, für die es im Klassifikationssystem des DSM-IV eine Reihe diagnostischer S...
The authors performed neuropsychological testing in 21 patients with myotonic dystrophy type 1 (DM1) and 21 with type 2 (DM2) and healthy controls. They detected no general cognitive deficit in either DM1 or DM2, but compared to controls, both groups of patients were inferior in tests of prefrontal functioning. Patient groups did not differ in any...
Neuropsychological investigations of amyotrophic sclerosis (ALS) patients revealed considerable discrepancies regarding neurocognitive functions. Some, but not all studies have suggested executive dysfunctioning and memory impairment, and there is a wide range of applied neuropsychological tests and results. In this study, we investigated the neuro...
Historische und literarische Beschreibungen (wie das Beispiel der Lady Macbeth von Shakespeare) machen deutlich, dass es sich bei der Zwangserkrankung um keine zivilisatorische Zeiterscheinung handelt, sondern um eine schon lange bekannte wichtige psychische Erkrankung, die mit einer Lebenszeitprävalenz von 2–3% einhergeht. Die Zwangserkrankung füh...
Although deficits in attention and executive functions in patients with Major Depressive Disorder (MDD) are well confirmed [Veiel, H.O.F., 1997. A preliminary profile of neuropsychological deficits associated with major depression. Journal of Clinical and Experimental Neuropsychology 19, 587–603.]. The database regarding the relationship between im...
Zusammenfassung. Theoretischer Hintergrund: Auf Grund der extrem eingeschränkten Kalorienzufuhr beim Fasten kommt es zu verschiedenen hormonellen- und Stoffwechselveränderungen. Fragestellung: Sind kognitive Funktionen bei einer Fastendauer von 72 Stunden beeinträchtigt? Methode: Es wurden 15 Teilnehmer eines Buchinger-Fastenkurses und eine nach Ge...
Grußwort Im Namen der Fachgruppe "Klinische Psychologie und Psychotherapie" der Deutschen Gesellschaft für Psychologie möchten wir Sie sehr herzlich zur 22. Fachgruppentagung für Klinische Psychologie und Psychothe rapie an der Martin-Luther-Universität in Halle begrüßen. Die Tagung wird an einem der schönsten Orte im Zentrum der Stadt, dem "Löweng...
The acquisition of conditional associations using neutral and individually threatening verbal stimuli was assessed in 16 females with anorexia nervosa (AN), obsessive-compulsive disorder (OCD), bulimia nervosa and normal controls, respectively. Groups did not differ in terms of age, sex, intelligence, depression, verbal memory and verbal fluency me...
The neuropsychology of delinquency represents a newer, more promising research area with implications that ore possibly relevant in practice. However, as the neuropsychologically oriented investigations reported in the literature failed to yield any consistent findings, on experimental-neuropsychological decision test was implemented in which short...
Zusammenfassung
Die Neuropsychologie der Delinquenz stellt ein neueres, viel versprechendes Forschungsgebiet mit möglicherweise praxisrelevanten Implikationen dar. Da die in der Literatur berichteten orientierenden neuropsychologischen Untersuchungen jedoch keine konsistenten Befunde ergaben, wurde ein experimentell-neuropsychologischer Entscheidun...
To obtain and analyze the strategies of human spatial behavior, the Kiel Locomotor Maze, a maze-like analogue, was used. The Kiel Locomotor Maze automatically records different types of spatial memory errors, distances and rotation angles, decision time, and reaction times for each move. 18 patients with cerebral tumors within the frontal, temporal...
We investigated the influence of age, sex and familiarity on spatial performance assessed with a pointing task in 84 children: 21 kindergartners, 21 first-graders, 21 fifth-graders and 21 sixth-graders. Spatial performance was assessed in the children's natural environment, their respective school or kindergarten. The children had to indicate the d...
To obtain and analyze the strategies of human spatial behavior, the Kiel Locomotor Maze, a maze-like analogue, was used. The Kiel Locomotor Maze automatically records different types of spatial memory errors, distances and rotation angles, decision time, and reaction times for each move. 18 patients with cerebral tumors within the frontal, temporal...
The present study set out to examine the recovery of spatial learning and cognitive mapping skills after severe TBI in childhood. A prospective investigation was carried out with repeated measures. Children with TBI (n = 18) and healthy matched controls (n = 18) were investigated while the children with TBI stayed in a rehabilitation facility (t0)...
Spatial behaviour was investigated using a spatial learning task based on the Radial Arm Maze, the Morris Water Maze, and open-field search-task procedures. Ninety-six healthy children from six age groups (3, 4, 5, 7, 10 and 12 years) with no history of CNS disorders were studied with respect to the emergence of position-, cue- and place responses....
Dieses Lehrbuch ist die Grundlage für die Ausbildung zum Psychologischen Psychotherapeuten mit Schwerpunkt Verhaltenstherapie
The role of locomotion in the acquisition and transfer of spatial knowledge was investigated in 144 five-, seven- and eleven-year-old children. Two experiments were conducted in the Kiel locomotor maze. In the first experiment, one group of children explored the spatial layout by walking through the maze, while another learned the maze by surveying...
