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Berislav Momčilović

Berislav Momčilović

MD, MSc, PhD

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147
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Publications

Publications (147)
Article
Objectives Short-term biological indicator of urinary Mg and Ca excretion helps us to assess human body Mg and Ca nutritional status. In this study, we used the long-term biological indicator tissue of hair to assess Mg and Ca human body nutritional status. Methods Hair Mg and Ca were analyzed in 1073 healthy white adult Caucasians [734 women (♀)...
Article
Full-text available
Background: Limbic dementia is a member of a cluster of various dementias that have no brain plaques and tangles. All dementias, including Alzheimer’s disease, are more prevalent in areas polluted with various chemical, physical, and biological contaminants. We studied generation of 210Po tagged exhaust particles from the internal combustion engine...
Article
Objectives Molybdenum is the essential trace element in human nutrition since it is a part of a pterin coenzyme which is essential for the activity of various oxidases. High doses of Mo are neurotoxic to the human brain. The safe adequate intake of Mo is set at 75–200 µg·g−1, but there is no available long-term biological indicator tissue to assess...
Article
Full-text available
Objectives Iodine and selenium are two essential trace elements intimately associated with the thyroid gland function. The aim of this study was to assess the combined hair iodine and selenium frequency distribution in the hair to assess their nutritional status and their mutual ratio. Methods Hair was collected in 1073 healthy adult subjects (339...
Conference Paper
Conclusions : Human nutritional status of Mn in the population may be reliably assessed byanalyzing its frequency distribution in the hair with the median derivatives bioassay. Ourexploration indicates how it is possible to diagnose the subclinical states of both manganesenutritional deficiency and excess. When the Mn nutritional status is expresse...
Conference Paper
Objectives : Iron is the essential trace element (TE) in human nutrition, but also the most frequently observed deficient element in the human nutrition. The aim of this study was to assess human iron nutritional status by assessing its frequency distribution in the hair with a median derivatives bioassay. Methods : In this prospective, observation...
Article
Objectives: Iron is the essential trace element (TE) in human nutrition, but also the most frequently observed deficient element in the human nutrition. The aim of this study was to assess human iron nutritional status by assessing its frequency distribution in the hair with a median derivatives bioassay. Methods: In this prospective, observatio...
Article
Objectives: Manganese (Mn) is the essential trace element (TE) in human nutrition, but high doses of Mn are toxic to the human mentation and induce brain extrapyramidal system. The main source of manganese is our diet, but there no availale long-term biological indicator for assessing the Mn nutritional status.The aim of this study was to assess h...
Article
Objective: Lithium was recently proclaimed to be an essential trace element in human nutrition. The aim of tins study was to assess lithium nutritional status by analyzing lithium frequency distribution in the long-term biological indicator tissue of hair (H-Li) and in the short-term biological indicator tissue of whole blood (WB-Li). Materials and...
Article
Full-text available
Background. We have studied human life expectancy in Croatia. Materials and Methods. Local daily papers reported obituaries for 447 men and 366 women who died in a month period. The data were analyzed with the median derivative power function model. Results. The median age of death was 76 and 81 years for men and women, respectively. Cumulative mor...
Article
The accurate assessment of the bioelement's nutritional status is a condition sine qua non for judicious usage of the hair multi-bioelement profiles in personalized medical practice. The term bioelement includes major elements and electrolytes, trace elements, and ultra-trace elements, since all of them are simultaneously entangled in the biologica...
Article
Full-text available
Dugotrajna akumulacija mangana u organizmu može uzrokovati anoreksiju, apatiju, glavobolju, grčeve u nogama, smetnje govora kao i sindrome slične encefalitisu te neurološke poremećaje poput parkinsonizma te psihijatrijske poremećaje poput naglih promjena raspoloženja, kompulzivnog ponašanja, a može se javiti i psihoza. Uvod Mangan je mineral, oligo...
Article
Full-text available
Dosadašnja istraživanja koncentracija elemenata u tragovima u kosi i ostalim biološkim matricama kod osoba sa shizofrenijom davala su kontradiktorne rezultate. Mogući uzrok tome vjerojatno su nedovoljno osjetljivi analitički postupci i različite metode mjerenja koje su upotrebljavane u istraživanjima. Uvod Bioelementi ili elementi u tragovima su sa...
Article
Full-text available
Background. We have studied human life expectancy in Croatia. Materials and Methods. Local daily papers reported obituitairies for 447 men and 366 women who died in a month period. The data were analyzed with the median derivative power function model. Results. The median age of death was 76 and 81 years for men and women, respectively. Cummulative...
Article
Full-text available
Background: Significant inconsistencies exist in findings on association of bio-elements (BE) concentrations and schizophrenia. Hypothesis of this research was that different concentrations of BE are associated with different psychopathological schizophrenia symptoms. Subjects and methods: This cross-sectional study was performed from 2014 to 2016...
Article
Background: Significant inconsistencies exist in findings on association of bio-elements (BE) concentrations and schizophrenia. Hypothesis of this research was that different concentrations of BE are associated with different psychopathological schizophrenia symptoms. Subjects and methods: This cross-sectional study was performed from 2014 to 20...
Conference Paper
Objectives. Today, depression is the most common human mental impairment in the world of unknown biochemical nature. Recent studies revealed that the low dietary lithium intake is associated with the increased incidence of human suicide, what is the gravest form of human depression. We have already demonstrated that the adequate human lithium nutri...
Article
The principles and practice of assessing the human body nutritional status or its environmental exposure through hair bioelement analysis are presented; herein the term "bioelements" is used as a common denominator for the major elements, trace elements and ultra-trace elements that are found in the human body. The accumulation of bioelements in th...
Article
Boron is a non-essential ubiquitous trace element in the human body. The aim of this study was to assess boron nutritional status by analyzing boron frequency distribution in the long-term biological indicator tissue of hair and the short-term biological indicator of whole blood. Hair samples were analyzed in 727 apparently healthy subjects (263 ♂...
Article
Boron is a non-essential ubiquitous trace element in the human body. The aim of this study was to assess boron nutritional status by analyzing boron frequency distribution in the long-term biological indicator tissue of hair and the short-term biological indicator of whole blood. Hair samples were analyzed in 727 apparently healthy subjects (263 ♂...
Article
The aim of this study was to assess the human environmental Li exposure by studying Li frequency distribution in the hair (H-Li) and whole blood (WB-Li). Hair (H) was collected in 1073 healthy adult subjects (339 e and 734 q); blood Li (B-Li) was analyzed in the sub-population of 91 e and 143 9). Samples were analyzed for Li with the ICP-MS at the...
Article
The aim of this study was to assess human boron (B) nutritional status. Hair (H) (samples were analyzed in 707 healthy adult subjects in (263 a and 464 9) with the ICP-MS at the CBM, Moscow, Russia. Whole blood (WB) B was assessed in the population sub-sample of 80 men and 152 women. The frequency distribution of B in the respective H and WB sample...
Article
Differing concentrations of trace elements (TE) may play a role in the pathogenesis of schizophrenia and major depressive disorder (MDD). The aim of this study was to compare such differences. This cross-sectional study was conducted in 2015 at the psychiatric hospitals Sveti Ivan and Vrapče in Zagreb, Croatia, on a consecutive sample of 75 patient...
Article
Full-text available
The aim of this study was to determine if altered levels of selected trace elements manifest themselves during chronic depression. To identify elements strongly associated with chronic depression, relationships between the elemental contents of hair and nails and the interelement correlations were checked. Inductively coupled plasma mass spectromet...
Article
Strontium (Sr) is a bone seeking trace element that closely parallels calcium metabolism. At the present, there is no avail- able long-term biological indicator for assessing the human Sr nutritional status. In this article, we have presented a novel concept on how to assess the human strontium nutritional status by studying its frequency distribut...
Conference Paper
Full-text available
Introduction: Schizophrenia is a severe mental disorder, characterized by profound disruptions in thinking, affecting language, perception, and the sense of self. Differences in the concentration of trače elements can play an important part in the pathogenesis of schizophrenia. Materials and methods: The target population included individuals diagn...
Article
Aluminum is an omnipresent non-essential trace element in the human diet and an essential component of numerous industrial processes. The Al population exposure risk is increasing, but there is no long-term biomarker for the exposure assessment. We analyzed Al with ICP MS in the hair (Al H) and whole blood (Al WB) in 311 healthy persons (n♂ = 123 a...
Article
Differences in concentrations of bioelements may play a role in the pathogenesis of schizophrenia. Previous studies have confirmed there are differences betvveen the concentration of bioelements but they have been done by insufficiently sensitive analytical procedures, and with no data on a larger number of bioelements inthe same sample ofbiologica...
Article
Lactating mother and her two month old healthy daughter (APGAR 10) gave their scalp hair for a multielement profile analysis; 25 elements were analyzed with the ICP MS. Mother's hair was divided into 5cm long segment proximal to the scull (Young), and the distal segment further up to the hair tip (Old). One centimeter of hair records one month of t...
Conference Paper
Full-text available
Razlike u koncentracijama bioelemenata mogu igrati ulogu u patogenezi shizofrenije. Nutritivna deprivacija u ranoj fazi života povećava rizik za razvoj shizofrenije, a oksidativni stres i poremećaji mišljenja koji su zajednički osobama sa shizofrenijom mogu biti posljedica promjena u razini određenih metala. Veći broj istraživanja potvrdio je hipot...
Conference Paper
Full-text available
Introduction: Differences in the concentration of BE can play an important part in the pathogenesis of schizophrenia. Oxidative stress and thought disorders, often frequent with individuals with schizophrenia, can be the consequence of an alteration in the level of certain metals. Most studies have confirmed the hypothesis that there are difference...
Article
Lactating mother and her two month old healthy daughter (APGAR 10) gave their scalp hair for a multi-element profile analysis; 25 elements were analyzed with the ICP MS. Mother's hair was divided into 5 cm long segment proximal to the scull (Young), and the distal segment further up to the hair tip (Old). One centimeter of hair records one month of...
Article
Vitamin B3 in the amide form (i.e., niacianamide; nicotinamide) decreased the urinary glucose excretion in a diabetes type-2, 73-year-old, Caucasian male.
Article
This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Editor-in-Chief. The article is a duplicate of a paper that has already been published in JOM, volume 28 (2013), 175–185, https://bib.irb.h...
Article
Today, human iodine deficiency is next to iron the most common nutritional deficiency in developed European and underdeveloped third world countries, respectively. A current biological indicator of iodine status is urinary iodine that reflects the very recent I odine exposure, whereas some long-term indicator of iodine status remains to be identifi...
Article
The transfer of lead 203 (203Pb) and calcium 47 (47Ca) from mother to fetuses and litter was examined 48 hours after a single intravenous application of both radioisotopes to rats on the 18th day of pregnancy and on the fourth and 15th day of lactation.
Article
Lead (Pb) transfer from mother to litter was investigated at the late stage of lactation after a single intraperitoneal injection of 2.0 μg Pb/ml marked with 203Pb . After 48 hr almost 20% of the maternal dose of 203Pb was found in the litter, and about 0.6 and 0.2% of the injected dose was found in the liver and kidneys of suckling rats, respectiv...
Article
Full-text available
Alzheimerova (AB) i Parkinsonova (PB) bolest su dva teška neuropsihijatrijska oboljenja nepoznate etiologije. U prethodnim smo istraživanjima uspjeli dokazati jasnu razliku u biokemijskim podlogama između te dvije bolesti (aMomčilović i sur. 2001). U tomu radu su detaljno prikazani epidemiološki i analitički postupci. Dok je sadržaj radioaktivnog p...
Article
Full-text available
Environmental exposure to silver (Ag) was assessed in occupationally non-exposed adult human population by analyzing Ag in the hair (H · Ag) and whole blood (WB · Ag). H · Ag was analyzed in 311 (123 men, M; 188 women, W); while WB · Ag was determined in 235 of these individuals (90 M, 145 W). Women had more H · Ag than men (M 0.05 vs. W 0.076), wh...
Article
Lead (Pb) disks were exposed to a radon (Rn)-rich atmosphere and surface alpha particle emissions were detected over time. Cumulative 210Po alpha emission increased nearly linearly with time. Conversely, cumulative emission for each of 218Po and 214Po was constant after one and two hours, respectively. Processing of radiation-free Pb ore (galena) i...
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Full-text available
th , 2012; revised July 10 th , 2012; accepted August 7 th , 2012 The purpose of the study was to elucidate the role of bioelements in human depression. We studied hair sodium and potassium in 311 adult subjects (188 women and 123 men) in the randomized, prospective, observational study; 192 were controls (83 men and 109 women), and 119 have major...
Article
Full-text available
The scientific project (SP) peer review process (PRP) is reviewed in the context of an virtual project and with the aim to identify the key stumbling blocks in the current practices of such SP reviewing in Croatia. Current practice of the PRP in Croatia is grossly non transparent and reminds of an »old boys club«. It's not known how the project rev...
Article
Full-text available
The recent development of the analytical techniques offers the unprecedented possibility to study simultaneously concentration of dozens of elements in the same biological matrix sample of 0.5–1.0 g (multielement profiles). The first part of this essay entitled “Think globally… An outline of trace elements in health and disease” aims to introduce t...
Chapter
Full-text available
he prevailing biological conditions in the human oral cavity induce the release of trace element (TE) metal cations from the dental casting alloys. We studied the release of metal ions (Al, Ag, Au, Ca, Cd, Co, Cr, Cu, Mg, Mo, Ni, Pd, Pt, Ti, and Zn) from three most common dental casting alloys, two base and one noble: Co▪Cr▪Mo, Ni▪Cr, and Au▪Pt all...
Article
Objectives. Understanding of the relationship between the iron and manganese metabolism in the human nutrition is lacking. The objective of this study was to compare the effect of low vs. high serum ferritin on the 54Mn gastrointestinal tract transit time (GIT) in women of reproductive age fed a low manganese diet. Subjects. In a randomized communi...
Article
Objective: The role of trace elements (TE) in hu an depression is poorly understood. In this exploratory study we examined the TE hair and blood multielement profile (MP) in respective depressed and healthy control subjects. Subjects: 48 depressed (15 men and 33 women) and 48 apparently healthy control (23 men and 25 women) subjects 23 - 92 years o...
Article
Objective: To assess the effect of intermittent custom-made dietary supplementation with Ca, Mg, and vitamin D based on an individual trace element (TE) multielement profile (MP) of the hair and whole blood (WB). Subjects: Initially, we used the hair and WB TEMP to assess Mg, Ca, and Si nutritional status of 48 healthy subjects of both sexes. After...
Article
Objective: Preliminary results of the exploratory study on trace element (TE) multielement profile (MP) hair analysis showed that the essential TE iodine, selenium, and copper are deficient in human depression (median values). The aim of this paper is to study the inter relationship of iodine, selenium, and copper in the hair of control vs. depress...
Conference Paper
Full-text available
We studied the effect of training exercise of professional soccer players (a simulated soccer match) on the levels of DNA damage in peripheral blood lymphocytes, especially 7,8-dihydro-8-oxo-2'-deoxyguanosine (8-oxodG), using the modified alkaline comet assay before and after the training. After the match, the values of tail length and tail intensi...
Chapter
IntroductionPhysical and Chemical Properties, and Analytical Methods Sources, Production, Important Compounds, Uses, Waste Products, and RecyclingDistribution in the Environment, in Foods, and in Living OrganismsUptake, Absorption, Transport and Distribution, Metabolism and Elimination in Plants, Animals, and HumansEffects on Plants, Animals, and H...
Article
We studied the seasonal variation of the environmental radon progeny (214)Bi activity in the whole bodies (WB) of women and men participating in community-based studies at the Grand Forks Human Nutrition Research Center (GFHNRC), the (214)Bi background activity of the GFHNRC whole body counter (WBC) steel room, and ambient air (222)Rn concentration...
Article
Full-text available
Background Radon is a ubiquitous noble gas in the environment and a primary source of harmful radiation exposure for humans; it decays in a cascade of daughters (RAD) by releasing the cell damaging high energy alpha particles. Results We studied natural distribution of RAD 210Po and 210Bi in the different parts of the postmortem brain of 86-year-o...
Article
Full-text available
The release of metal ions (Al, Ag, Au, Ca, Cd, Co, Cr, Cu, Mg, Mo, Ni, Pd, Pt, Ti, and Zn) from the commercial gold/platinum (Au/Pt) dental alloy of declared composition was studied. Au/Pt was soaked in pH 6.0 phosphate buffer, 3.5 pH phosphate buffer and pH 3.5 mixture of lactic, formic and acetic acid, and incubated at 37 degrees C for 1, 2, 3, 4...