Berend Terluin

Berend Terluin
Amsterdam University Medical Center | VUmc · Department of General Practice and Elderly Care Medicine

MD, PhD

About

268
Publications
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6,155
Citations

Publications

Publications (268)
Article
Full-text available
Introduction General practitioners (GPs) often face challenges in explaining to patients with persistent physical symptoms (PPS) why their symptoms persist. Providing an explanation of the central sensitisation (CS) mechanism to patients could be helpful, yet GPs do not routinely test for signs of CS in these patients. The aim of this study was to...
Preprint
Full-text available
Analytical validation (AV) is a crucial step in the evaluation of algorithms that process data from sensor-based digital health technologies (sDHTs). AV of novel digital measures can be complicated when reference measures with direct correspondence are not available. To address this, we conducted a simulation study. Data was simulated assuming a la...
Article
Full-text available
Purpose The minimal important change (MIC) in a patient-reported outcome measure is often estimated using patient-reported transition ratings as anchor. However, transition ratings are often more heavily weighted by the follow-up state than by the baseline state, a phenomenon known as “present state bias” (PSB). It is unknown if and how PSB affects...
Article
Full-text available
Background Primary care clinicians see people experiencing the full range of mental health problems. Determining when symptoms reflect disorder is complex. The Four-Dimensional Symptom Questionnaire (4DSQ) uniquely distinguishes general distress from depressive and anxiety disorders. It may support diagnostic conversations and targeting of treatmen...
Article
Full-text available
Purpose The minimal important change (MIC) is defined as the smallest within-individual change in a patient-reported outcome measure (PROM) that patients on average perceive as important. We describe a method to estimate this value based on longitudinal confirmatory factor analysis (LCFA). The method is evaluated and compared with a recently publis...
Article
OBJECTIVE: To evaluate the change in minimal important change (MIC), patient acceptable symptom state (PASS), and treatment failure (TF) thresholds for the Knee injury and Osteoarthritis Outcome Score (KOOS) from 3 to 12 months following arthroscopic meniscus surgery. DESIGN: Retrospective cohort study. METHODS: We included patients from the Knee A...
Method
Full-text available
It is a national multidisciplinary guideline for treatment of overstrain and burnout by GP, company doctor and psychologist.
Article
Objectives: Clinical interpretability of the gait speed and 5-times sit-to-stand (5-STS) tests is commonly established by comparing older adults with and without self-reported mobility limitations (SRML) on gait speed and 5-STS performance, and estimating clinical cutpoints for SRML using the receiver operating characteristics (ROC) method. Accumu...
Preprint
Full-text available
Introduction GPs struggle to explain to patients with persistent physical symptoms (PPS) why their symptoms persist. Providing an explanation of the central sensitisation (CS) mechanism to patients could be helpful, yet GPs do not test for signs of CS in patients. Our aim was to explore whether applying a test for assessing CS is valuable for the e...
Article
Background: Patient-reported outcome measures such as the Oxford Hip Score (OHS) can capture patient-centered perspectives on outcomes after total hip arthroplasty (THA). The OHS assesses hip pain and functional limitations, but defining interpretation threshold values for the OHS is warranted so that numerical OHS values can be translated into wh...
Article
Objective: To extend the anchor-based minimal important differences (MIDs) credibility instrument by adding an item addressing construct proximity as the alternative to the correlation item. Study design and setting: The credibility instrument includes one core items addressing the correlation between the patient-reported outcome measure (PROM)...
Article
Full-text available
Purpose Meaningful thresholds are needed to interpret patient-reported outcome measure (PROM) results. This paper introduces a new method, based on item response theory (IRT), to estimate such thresholds. The performance of the method is examined in simulated datasets and two real datasets, and compared with other methods. Methods The IRT method i...
Article
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The diversity of measures in clinical psychology hampers a straightforward interpretation of test results, complicates communication with the patient, and constitutes a challenge to the implementation of measurement-based care. In educational research and assessment, it is common practice to convert test scores to a common metric, such as T scores....
Article
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We evaluated the responsiveness of the PROMIS Pain Interference item bank in patients with musculoskeletal pain by testing predefined hypotheses about the relationship between the change scores on the item bank, change scores on legacy instruments and Global Ratings of Change (GRoC), and we estimated Minimal Important Change (MIC). Patients answere...
Article
Full-text available
Objective The goal of this study was to compare the 15-item Patient Health Questionnaire (PHQ-15) and the somatization subscale of the Four-Dimensional Symptoms Questionnaire (4DSQ-S) with respect to their latent structure and reliability, and to examine whether their scores are affected by age and gender, and whether the scales measure the same co...
Article
Objective We synthesised and assessed credibility (ie, trustworthiness) of thresholds that define meaningful scores for patient-reported outcome measures (PROMs) following interventions for anterior cruciate ligament (ACL) tear or traumatic meniscus injury. Design Systematic review, narrative synthesis. Data sources We searched five databases, ha...
Article
Full-text available
Purpose Thresholds for meaningful within-individual change (MWIC) are useful for interpreting patient-reported outcome measures (PROM). Transition ratings (TR) have been recommended as anchors to establish MWIC. Traditional statistical methods for analyzing MWIC such as mean change analysis, receiver operating characteristic (ROC) analysis, and pre...
Article
Full-text available
Background and purpose: Developing meaningful thresholds for the Oxford Knee Score (OKS) advances its clinical use. We determined the minimal important change (MIC), patient acceptable symptom state (PASS), and treatment failure (TF) values as meaningful thresholds for the OKS at 3-, 12-, and 24-month follow-up in patients undergoing unicompartmen...
Article
Full-text available
Objective Patients with persistent physical symptoms (PPS) require an explanation that is acceptable and comprehensible to them. Central sensitisation (CS) is an explanatory model for PPS and chronic pain that has been broadly applied in the context of pain medicine, but, until recently, not by general practitioners (GPs). We explored how GPs used...
Article
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Voor veel patiënten is het moeilijk om hun aanhoudende lichamelijke klachten (ALK) te accepteren. Ze blijven vaak (te) lang zoeken naar een verklaring. Huisartsen staan voor de lastige taak om hen te motiveren om op een adequate manier met hun klachten om te gaan. Bij de uitleg hiervan kunnen ze van centrale sensitisatie gebruikmaken, een van de ve...
Article
Full-text available
Objectives The anchor-based minimal important change (MIC), based on receiver operating characteristic (ROC) analysis or predictive modeling, is biased by the proportion of improved patients. The adjusted MIC, published in 2017, adjusts the predictive MIC for this bias but does not take the reliability of the transition ratings (i.e., the anchor) i...
Preprint
Full-text available
Background The Vertigo Symptom Scale – Short Form (VSS-SF) is a widely used questionnaire to measure vestibular symptoms such as dizziness and vertigo. We aimed to translate and cross-culturally validate the Dutch version of the VSS-SF. Methods We performed a psychometric evaluation study in general practice. First, we followed international guidel...
Article
Full-text available
Objective Patient-reported transition ratings are supposed to reflect the change between a previous baseline health state and a present follow-up state, but may reflect the present state to a greater extent. This so-called ‘present state bias’ (PSB) potentially threatens the validity of transition ratings. Several criteria have been proposed to ass...
Article
Objective : To systematically survey the literature addressing the reporting of studies estimating anchor-based minimal important differences (MIDs) and choice of optimal MIDs. Study design and Setting : We searched Medline, Embase and PsycINFO from 1987 to March 2020. Teams of two reviewers independently identified eligible publications and extra...
Article
Background – The minimal important change (MIC) of the 6-minute walk test (6MWT) is not clear for patients with Multiple Sclerosis (MS), hampering treatment evaluation. The aim of our study was therefore to determine the MIC of the 6MWT in MS patients. Methods – MS patients did the 6MWT using the instruction to walk at comfortable speed twice with...
Article
Full-text available
Introduction Central sensitization (CS) may explain the persistence of symptoms in patients with chronic pain and persistent physical symptoms (PPS). There is a need for assessing CS in the consultation room. In a recently published systematic review, we made an inventory of tests for CS. In this study we aimed to assess which tests might have adde...
Article
Full-text available
Purpose The minimal important change (MIC) of a patient-reported outcome measure (PROM) is often suspected to be baseline dependent, typically in the sense that patients who are in a poorer baseline health condition need greater improvement to qualify as minimally important. Testing MIC baseline dependency is commonly performed by creating two or m...
Article
Objective: Patient reported outcomes (PRO) are widely used in quality of life (QOL) studies, health outcomes research, and clinical trials. The importance of PRO has been advocated by health authorities. Patient Reported Outcomes Measurement Information System (PROMIS®) is a collection of standardized measures of PROs using Item Response Theory (I...
Article
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Purpose Although common mental disorders (CMDs) highly impact individuals and society, a knowledge gap exists on how sickness absence can be prevented in workers with CMDs. This study explores: (1) workers’ perceived causes of sickness absence; (2) perceived return to work (RTW) barriers and facilitators; and (3) differences between workers with sh...
Article
De Vierdimensionale Klachtenlijst (4DKL) wordt in de huisartsenpraktijk veel gebruikt om psychische klachten in kaart te brengen. Huisartsen vragen zich wel eens af of de 4DKL wel hetzelfde meet bij mensen met een migratieachtergrond als bij mensen met een Nederlandse achtergrond. En mogen we de scores op dezelfde manier interpreteren? Om deze vrag...
Article
Introduction : Transition ratings (TRs) are single item measures which ask patients to report on their health change. They allow for a simple assessment of improvement or deterioration and are frequently used as an “anchor” to determine interpretation thresholds on an patient-reported outcome measure (PROM). Despite their widespread use, a routinel...
Article
Full-text available
We define the minimal important change (MIC) as a threshold for a minimal within-person change over time above which patients perceive themselves importantly changed. There is a lot of confusion about the concept of MIC, particularly about the concepts of minimal important change and minimal detectable change, which questions the validity of publis...
Article
Full-text available
Mental health problems are highly prevalent in primary care. Validated tools to detect mental disorders in general practice are needed. The Four-Dimensional Symptom Questionnaire (4DSQ) was designed to help GPs differentiating between psychological distress and psychopathological conditions (depression, anxiety, somatization). The aim of the curren...
Preprint
Full-text available
PURPOSE: Thresholds for meaningful within-individual change (MWIC) are useful for interpreting patient-reported outcome measures (PROM). Transition ratings (TR) have been recommended as anchors to establish MWIC. Traditional statistical methods for analyzing MWIC such as mean change analysis, receiver operating characteristic (ROC) analysis, and pr...
Preprint
Full-text available
Purpose The minimal important change (MIC) of a patient-reported outcome measure (PROM) is often suspected to be baseline dependent, typically in the sense that patients who are in a poorer baseline health condition need greater improvements to qualify as minimally important. Testing MIC baseline dependency is commonly performed by creating two or...
Article
Objectives: To determine the proportions of patients who (i) perceived their symptoms to be satisfactory (ii) perceived their treatment to have failed, or (iii) perceived having improved to an important degree at three months after arthroscopic meniscal surgery. To determine Knee Injury and Osteoarthritis Outcome Score (KOOS) subscale scores corre...
Article
Full-text available
Background and purpose — Meaningful interpretation of postoperative Oxford Knee Score (OKS) levels is challenging. We established Patient Acceptable Symptoms State (PASS) and Treatment Failure (TF) values for the OKS in patients undergoing primary total knee replacement (TKR) in Denmark. Patients and methods — Data from patients undergoing primary...
Article
Doctors and patients are often not satisfied about the treatment of medically unexplained symptoms (MUS) and chronic pain. Central sensitization (CS) plays an important role in chronic pain and regularly also in MUS and can be used for explanation to these patients. This explanation can cause acceptance and understanding, leading to cessation of fu...
Article
Full-text available
Aims: The Dutch Four-Dimensional Symptom Questionnaire (4DSQ) measures distress, depression, anxiety and somatisation, facilitating the distinction between stress-related problems and psychiatric disorder in primary and occupational health care. The aim of the study was to examine the measurement equivalence across the Danish and Dutch 4DSQ. Method...
Article
Objective The somatosensory amplification theory considers symptom focusing and somatosensory amplification as important perpetuating factors of persistent physical symptoms. We investigated whether symptom focusing and somatosensory amplification were associated with symptom severity and mental and physical functioning over a three-year period in...
Article
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Objective This study introduces a new method to establish clinical thresholds for multi-item tests, based on item response theory (IRT), as an alternative to receiver operating characteristic (ROC) analysis. The performance of the IRT method was examined and compared with the ROC method across multiple simulated datasets and in a real dataset. Stu...
Article
Uit een cochranereview naar het effect van motiverende gespreksvoering als stoppen-met-rokeninterventie blijkt dat het resultaat tegenvalt. Een half jaar na de interventie is het percentage stoppers niet groter dan na geen of een andere interventie.
Article
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Objective: detection of depression is a key part of primary mental health care. However, determining whether depressive disorder is or is not present in primary care patients is complex. The aim of this qualitative study was to explore General Practitioners’ (GPs) perceptions of distinctions between emotional distress and depressive disorder. Des...
Article
Full-text available
The Four-Dimensional Symptom Questionnaire (4DSQ) is a self-report instrument measuring distress, depression, anxiety and somatization. The questionnaire has been developed and validated in adult samples. It is unknown whether adolescents and emerging adults respond to the 4DSQ items in the same way as adults do. The objective of the study was to e...
Article
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Abstract Background As compliance to guidelines is generally low among health care providers, little is known about the impact of guidelines on the quality of delivery of care. To improve adherence to guideline recommendations on mental health problems, an implementation strategy was developed for Dutch occupational physicians (OPs). The aims were...
Article
We studied the psychometric properties of the 39-item v1.1 Dutch-Flemish Patient-Reported Outcomes Measurement Information System Pain Behavior item bank in a sample of 1,602 patients with musculoskeletal complaints. We evaluated the assumptions of the underlying item response theory (IRT) model (unidimensionality and local dependency with confirma...
Article
Full-text available
Background The Four-Dimensional Symptom Questionnaire (4DSQ) is a self-report questionnaire designed to measure distress, depression, anxiety, and somatization. Prior to computing scale scores from the item scores, the three highest response alternatives (‘Regularly’, ‘Often’, and ‘Very often or constantly present’) are usually collapsed into one c...
Preprint
Full-text available
Objective Central sensitization (CS), a mechanism explaining the persistence of symptoms, has been the focus of many research projects. Explanations given to patients with chronic pain are often based on this mechanism. It is hypothesized that CS also plays an important role in the persistence of medically unexplained symptoms (MUS). However, defin...
Chapter
Depressieve stoornissen worden veroorzaakt door een ontregeling van de stemmingsregulatie. Deze moeten worden onderscheiden van normale depressieve reacties op verlies en tegenslagen. Kenmerkend voor stoornissen zijn onder meer het verlies van het vermogen om te genieten van gewone dingen (anhedonie) en een voortdurende negatieve beleving van de ei...
Chapter
Stressgerelateerde klachten worden gekenmerkt door distress (een onaangename emotionele spanningstoestand) en kunnen worden onderverdeeld in spanningsklachten, overspanning en burn-out. Als de patiënt nog in staat is normaal te functioneren, spreken we van spanningsklachten. Als de patiënt het niet meer aan kan en sociaal disfunctioneert, is er spr...
Article
Objective: The Barthel index (BI) is a widely used observer-based instrument to measure physical function. Our objective is to assess the structural validity, reliability, and interpretability of the BI in the geriatric rehabilitation setting. Design: Two studies were performed. First, a prospective cohort study was performed in which the attend...
Article
Study design: Cross sectional study. Objective: To validate the Dutch-Flemish PROMIS Pain Interference item bank in patients with musculoskeletal complaints. Summary of background data: PROMIS item banks have been developed and validated in the US. They need to be further validated in various patient populations and in different languages. Me...
Article
Purpose: Psychosomatic symptoms and mental health problems are highly prevalent in multimorbid elderly people challenging general practitioners to differentiate between normal stress and psychopathological conditions. The 4DSQ is a Dutch questionnaire developed to detect anxiety, depression, somatization, and distress in primary care. This study a...
Article
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Background: Adequate recognition of anxiety and depression by general practitioners (GPs) can be improved. Research on factors that are associated with recognition is limited and shows mixed results. The aim of this study was to explore which patient and GP characteristics are associated with recognition of anxiety and depression. Methods: We pe...
Article
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Background and purpose — Interpreting changes in Oxford Knee Score (OKS) and Forgotten Joint Score (FJS) following total knee replacement (TKR) is challenged by the lack of methodologically rigorous methods to estimate minimal important change (MIC) values. We determined MIC values by predictive modeling for the OKS and FJS in patients undergoing p...
Article
Full-text available
Purpose: Many paper-and-pencil (P&P) questionnaires have been migrated to electronic platforms. Differential item and test functioning (DIF and DTF) analysis constitutes a superior research design to assess measurement equivalence across modes of administration. The purpose of this study was to demonstrate an item response theory (IRT)-based DIF a...
Article
Eerdere onderzoeken toonden aan dat de NVAB-richtlijn Psychische problemen in de praktijk zeer weinig gebruikt wordt. Dit artikel geeft een overzicht van de barrières die bedrijfsartsen ervaren bij het gebruik van deze richtlijn. 31 bedrijfsartsen bespraken in zes groepen de inhoud en aanbevelingen, in acht bijeenkomsten. De geluidsopnames werden l...
Article
Full-text available
Background: Meaningful change scores in the Knee injury and Osteoarthritis Outcome Score (KOOS) in patients undergoing anterior cruciate ligament (ACL) reconstruction have not yet been established. Purpose: To define the minimal important change (MIC) for the KOOS after ACL reconstruction. Study design: Cohort study (diagnosis); Level of evide...