Benjamin PosorskeBrigham and Women's Hospital | BWH · Division of Hematology
Benjamin Posorske
About
2
Publications
1,001
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22
Citations
Citations since 2017
Introduction
Additional affiliations
June 2013 - July 2016
Position
- Research Assistant
Description
- Meng Lab- Cardiothoracic Surgery Research
Education
August 2016 - May 2020
Publications
Publications (2)
Background
The mechanisms that regulate platelet biogenesis remain unclear; factors that trigger megakaryocytes (MKs) to initiate platelet production are poorly understood. Platelet formation begins with proplatelets which are cellular extensions originating from the MK cell body.
Objectives
Proplatelet formation is an asynchronous and dynamic pro...
Megakaryocytes (MKs) are specialized precursor cells committed to producing and proliferating platelets. In a cytoskeletal-driven process, mature MKs generate platelets by releasing thin cytoplasmic extensions, named proplatelets, into the sinusoids. Due to knowledge gaps in this process and mounting clinical demand for non-donor-based platelet sou...
Projects
Project (1)
