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Benjamin Malcolm

Benjamin Malcolm
Spirit Pharmacist

Doctor of Pharmacy, Master of Public Health

About

19
Publications
9,935
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219
Citations
Introduction
Ben Malcolm is a Board Certified Psychiatric Pharmacist (BCPP). His primary passion in the field is psychedelic drugs, although is also interested antipsychotics, antidepressants, as well as alternative medicines such as essential oils. He offers psychopharmacology consulting, educational courses, a membership program and more at spiritpharmacist.com
Additional affiliations
July 2015 - November 2015
University of California, San Diego
Position
  • PGY2 Psychiatric Pharmacy Resident

Publications

Publications (19)
Article
Full-text available
Recent research suggests that functional connectivity changes may be involved in the pathophysiology of psychiatric disorders. Hyperconnectivity in the default mode network has been associated with psychopathology, but psychedelic serotonin agonists like psilocybin may profoundly disrupt these dysfunctional neural network circuits and provide a nov...
Poster
Full-text available
Background: Problematic opioid consumption is currently an epidemic in the United States. Ibogaine is reported to have the ability to interrupt opioid addiction by simultaneously mitigating withdrawal and craving symptoms. Objective: Evaluate opioid withdrawal and drug craving scores using validated clinical instruments in subjects with problematic...
Article
Ayahuasca is a traditional psychoactive sacrament that’s been used in Amazonian shamanic rituals for hundreds of years. Ayahuasca is notorious for its psychedelic properties produced from the combination of monoamine oxidase inhibitors (MAOIs) found in the Banisteriopsis caapi vine and N-N-dimethyltryptamine from Psychotria viridis or Diplopterys c...
Poster
Full-text available
Purpose Several recent randomized controlled trials have shown rapid efficacy of intravenous (IV) low-dose (0.5 mg/kg) ketamine infusions for patients with treatment refractory depression (TRD). However, because these studies excluded patients with certain comorbid psychiatric conditions, suicide risk, and concomitant psychotropic medications, the...
Article
Objective To measure the impact of student pharmacists’ consultation on participant knowledge and attitudes about influenza and tetanus–diphtheria–acellular pertussis (Tdap) vaccines. Design Pre- and post-consultation surveys. Setting Free health care service and immunization clinics in Vallejo and Martinez, CA. Participants Children and adults...
Article
Full-text available
Rationale & objectives ± 3,4-Methylenedioxymethamphetamine (MDMA) and psilocybin are currently moving through the US Food and Drug Administration’s phased drug development process for psychiatric treatment indications: posttraumatic stress disorder and depression, respectively. The current standard of care for these disorders involves treatment wit...
Article
The ‘kambô’ ritual involves application of Phyllomedusa Bicolor poison to superficial burns made on the user’s skin. Existing kambô literature describes case reports of severe harms. The objective of the current study was to better characterize typical observed responses to kambô administration. We performed a retrospective review of a kambô practi...
Article
Full-text available
RationaleIn recent years, psychedelic substances with serotonergic mechanisms have accumulated substantial evidence that they may provide therapeutic benefits for people suffering with psychiatric symptoms. Psychiatric disorders targeted by these psychedelic-assisted therapies are managed with serotonergic drugs like selective serotonin reuptake in...
Chapter
In an attempt to comprehensively review the adverse effects of psychedelics, toxicology literature associated with unsafe recreational environments was also selectively reviewed for reports of adverse effects that may be generalizable to a therapeutic setting, but more robust evidence from clinical trial research is emphasized in this chapter.
Article
This case report describes a 39-year-old male with remote history of polysubstance use disorder and depression who developed tinnitus after use of inhaled N,N-dimethyltryptamine (DMT). Although development of ear ringing was attributed to use on a single occasion, tinnitus occurred within the context of a larger self-experiment involving weekly mic...
Article
Full-text available
Pharmacist-psychiatrist collaborative clinic models in specialty mental health clinics are limited, and there has been only 1 report of a clinic focused on adult attention-deficit hyperactivity disorder (ADHD). In this article, we describe the successful implementation of a pharmacist-psychiatrist collaborative practice agreement in an adult ADHD c...
Article
Essential oil extracted from eucalyptus leaves has a long folkloric history of being used for the treatment of respiratory conditions. The primary terpenoid constituent in the essential oil of eucalyptus (EOE) is eucalyptol (1,8-cineole or cineole), which has been studied in both preclinical and clinical settings. Eucalyptol displays several pharma...
Article
Full-text available
Introduction: Antipsychotics improve symptoms associated with schizophrenia and bipolar disorder. To improve medication adherence and decrease the need for hospitalization, many antipsychotics have been developed into long-acting injectable (LAI) formulations. Though mirror-image studies have demonstrated significantly decreased hospitalization ra...
Article
Full-text available
Opioid use disorder (OUD) is currently an epidemic in the United States (US) and ibogaine is reported to have the ability to interrupt opioid addiction by simultaneously mitigating withdrawal and craving symptoms. This study examined opioid withdrawal and drug craving scores in 50 participants with OUD undergoing a week-long detoxification treatmen...
Chapter
Ibogaine is a plant-derived alkaloid and dissociative psychedelic that demonstrates anti-addictive properties with several substances of abuse, including alcohol. 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a naturally occurring psychedelic known to occasion potent mystical-type experiences and also demonstrates anti-addictive properties. The p...
Article
Anxiety disorders are some of the most common psychiatric disorders, with potentially debilitating consequences on individual function. Existing pharmacotherapies for anxiety disorders are limited by delay to therapeutic effect, dependence, tolerance, withdrawal, and abuse potential. Therefore, safe and evidence-based complementary or alternative t...
Article
Background Recent studies demonstrating a rapid, robust improvement in treatment resistant depression (TRD) following a single sub-anesthetic infusion of ketamine have generated much excitement. However, these studies are limited in their generalizability to the broader TRD population due to their subject exclusion criteria which typically limit ps...
Conference Paper
Background: Several studies suggest that the distribution of written vaccination information is largely ineffective in changing attitudes and increasing knowledge in patients, while direct patient counseling and media productions are shown to be effective. The role of student pharmacists in educating patients on immunizations has not been clearly e...

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