Bénitière Florian- PhD in Evolutionary Genomics & Engineer in Bioinformatics
- Bioinformatician at CHU Sainte-Justine
Bénitière Florian
- PhD in Evolutionary Genomics & Engineer in Bioinformatics
- Bioinformatician at CHU Sainte-Justine
Bioinformaticist at the Jacquemont Lab
About
9
Publications
409
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
25
Citations
Introduction
Working at the Jacquemont Lab on Single Nucleotide Variants (SNVs) and Copy Number Variants (CNVs), exploring their impact on neuropsychiatric disorders across hundreds of thousands of individuals.
Current institution
Additional affiliations
September 2024 - present
Centre de recherche du CHU Sainte-Justine
Position
- Research Bioinformatician
December 2021 - June 2024
Laboratory of the Ecology of Natural and Anthropised Hydrosystems (LEHNA)
Position
- Research Engineer
September 2018 - August 2024
Biometry and Evolutionary Biology Laboratory (LBBE)
Position
- Research Engineer
Description
- The objective of my work is to estimate to what extent the effective size of the populations (Ne, which defines the intensity of the genetic drift) influences the evolution of the structure and the complexity of the expression of the genes in metazoa. This project requires significant bioinformatics developments to ensure the analysis and management of large volumes of data.
Education
December 2021 - May 2024
January 2015 - September 2019
Publications
Publications (9)
Most eukaryotic genes undergo alternative splicing (AS), but the overall functional significance of this process remains a controversial issue. It has been noticed that the complexity of organisms (assayed by the number of distinct cell types) correlates positively with their genome-wide AS rate. This has been interpreted as evidence that AS plays...
We present GTDrift, a comprehensive data resource that enables explorations of genomic and transcriptomic characteristics alongside proxies of the intensity of genetic drift in individual species. This resource encompasses data for 1,507 eukaryotic species, including 1,414 animals and 93 green plants, and is organized in three components. The first...
Early studies in invertebrate model organisms (fruit flies, nematodes) showed that their synonymous codon usage is under selective pressure to optimize translation efficiency in highly expressed genes (a process called translational selection). In contrast, mammals show little evidence of selection for translationally optimal codons. To understand...
Early studies in invertebrate model organisms (fruit flies, nematodes) showed that their synonymous codon usage is under selective pressure to optimize translation efficiency in highly expressed genes (a process called translational selection). In contrast, mammals show little evidence of selection for translationally optimal codons. To understand...
We present GTDrift, a comprehensive data resource that enables explorations of genomic and transcriptomic characteristics alongside proxies of the intensity of genetic drift in individual species. This resource encompasses data for 1506 eukaryotic species, including 1413 animals and 93 green plants, and is organized in three components. The first t...
Most eukaryotic genes undergo alternative splicing (AS), but the overall functional significance of this process remains a controversial issue. It has been noticed that the complexity of organisms (assayed by the number of distinct cell types) correlates positively with their genome-wide AS rate. This has been interpreted as evidence that AS plays...
Most eukaryotic genes undergo alternative splicing (AS), but the overall functional significance of this process remains a controversial issue. It has been noticed that the complexity of organisms (assayed by the number of distinct cell types) correlates positively with their genome-wide AS rate. This has been interpreted as evidence that AS plays...
Most eukaryotic genes undergo alternative splicing (AS), but the overall functional significance of this process remains a controversial issue. It has been noticed that the complexity of organisms (assayed by the number of distinct cell types) correlates positively with their genome-wide AS rate. This has been interpreted as evidence that AS plays...
Most eukaryotic genes undergo alternative splicing (AS), but the overall functional significance of this process remains a controversial issue. It has been noticed that the complexity of organisms correlates positively with their genome-wide AS rate. This has been interpreted as evidence that AS plays an important role in adaptive evolution by incr...
