Benedict U Nwachukwu

Benedict U Nwachukwu
Hospital for Special Surgery · Department of Orthopaedic Surgery

MD, MBA

About

327
Publications
35,801
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6,127
Citations
Additional affiliations
June 2013 - present
Hospital for Special Surgery
Position
  • Orthopedic Surgery Resident
November 2008 - May 2013
Brigham and Women's Hospital
Position
  • Research Assistant

Publications

Publications (327)
Article
Background: Minimal clinically important difference (MCID) defines the minimum degree of quantifiable outcome improvement that a patient perceives as the result of an intervention or in the process of healing. Substantial clinical benefit (SCB) defines the amount of quantifiable outcome improvement that is needed for a patient to feel substantiall...
Article
Full-text available
Type II SLAP tears are considered the most common type of SLAP lesions. However, the management of type II SLAP tears in middle-aged patients is challenging because recent evidence suggests that there is a high prevalence of type II SLAP lesions in the asymptomatic middle-aged shoulder. Treatment options for type II SLAP lesions in middle-aged pati...
Article
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Background: A greater emphasis on providing high-value orthopaedic interventions has resulted in increased health economic reporting. The contingent-valuation method (CVM) is used to determine consumer valuation of the benefits provided by healthcare interventions. CVM is an important value-based health economic tool that is underutilized in ortho...
Article
Purpose: To define minimal clinically important difference (MCID) and substantial clinical benefit (SCB) in revision hip arthroscopy. Methods: The modified Harris Hip Score (mHHS), the Hip Outcome Score (HOS), and the international Hip Outcome Tool (iHOT-33) were administered to revision hip arthroscopy patients. At 1 year postoperatively, patie...
Article
Background: Computerized adaptive testing (CAT) for patient-reported outcomes (PROs) is a developing area within orthopedic surgery. Our objective was to validate the Patient Reported Outcomes Measurement Information System (PROMIS) CATs for upper extremity fracture care. We sought to correlate PROMIS with legacy PROs and to investigate floor and...
Article
Background: Individualized risk prediction has become possible with machine learning (ML), which may have important implications in enhancing clinical decision making. We previously developed an ML algorithm to predict propensity for clinically meaningful outcome improvement after hip arthroscopy for femoroacetabular impingement syndrome. External...
Article
Applications of artificial intelligence, specifically machine learning, are becoming increasingly popular in Orthopaedic Surgery, and medicine as a whole. This growing interest is shared by data scientists and physicians alike. However, there is an asymmetry of understanding of the developmental process and potential applications of machine learnin...
Article
Due to its frequent misuse, the p value has become a point of contention in the research community. In this editorial, we seek to clarify some of the common misconceptions about p values and the hazardous implications associated with misunderstanding this commonly used statistical concept. This article will discuss issues related to p value interpr...
Chapter
Femoroacetabular impingement is one of the causes of hip pain leading to acetabular labral tears and articular cartilage damage via mechanical overload that may lead to the development of early osteoarthritis. However, other causes of impingement have been described that may be associated with painful nonarthritic hip. Subspine impingement is cause...
Chapter
Tears of the gluteus medius and/or minimus may be associated with tendinosis, retraction, fatty infiltration, and atrophy that preclude or compromise primary repair. Several techniques have emerged to address these concerns, including tendon transfers and augmentation with allograft, autograft, xenograft, or synthetic tissue. However, available tec...
Article
Telemedicine is an established method of providing health care through digital mediums and has recently gained much attention within the field of orthopaedic surgery because of the social and biologic pressures imposed by COVID-19. However, a more diverse and all-encompassing concept of healthcare digitalization, deemed Telehealth, has emerged simu...
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The purpose of this study was to perform an initial, prospective evaluation of imaging findings and outcomes after open surgical repair of gluteus medius tendon tears with bioinductive collagen patch augmentation. A prospective study was performed of patients with clinical and magnetic resonance imaging (MRI) evidence of symptomatic gluteus medius...
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Osteonecrosis of the femoral head (ONFH) is caused when circulation within the femoral head is disrupted. Etiology of this disease is characterized by either traumatic events or atraumatic risk factors, such as chronic alcohol consumption or glucocorticoid use. ONFH commonly presents as pain in the groin, gluteus muscles, and/or knee with reduction...
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Introduction Patient-reported outcome measures (PROMs) are essential to patient-centered care in orthopaedics. PROMIS measures have demonstrated reliability, validity, responsiveness, and minimal floor and ceiling effects in various populations of patients receiving orthopaedic care but have not yet been examined in hip fracture patients. This pilo...
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Background Clinically significant outcomes (CSOs) connect patient-reported outcome measures data to patient-perceived benefit. Although investigators have established threshold values for various CSOs, the timeline to achieve these outcomes after isolated biceps tenodesis (BT) has yet to be defined. Purpose To define the time-dependent nature of m...
Article
Purpose The purpose was to assess the clinical utility of preoperative MRI and quantify the delay in surgical care for patients aged 40 or younger undergoing primary hip arthroscopy with a history, physical examination, and radiographs concordant with femoroacetabular impingement syndrome (FAIS). Methods Between August 2015 and December 2020, 1,78...
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Full-text available
Purpose of Review Anterior cruciate ligament (ACL) rupture is a common injury that has important clinical and economic implications. We aimed to review the literature to identify gender, racial and ethnic disparities in incidence, treatment, and outcomes of ACL injury. Recent Findings Females are at increased risk for ACL injury compared to males....
Article
Background Graft failure after osteochondral allograft transplantation (OCA) of the knee is a devastating outcome, often necessitating subsequent interventions. A comprehensive understanding of the risk factors for failure after OCA of the knee may provide enhanced prognostic data for the knee surgeon and facilitate more informed shared decision-ma...
Article
Background The effect of surgical latency on outcomes of anterior cruciate ligament reconstruction (ACLR) is a topic that is heavily debated. Some studies report increased benefit when time from injury to surgery is decreased while other studies report no benefit. The purpose of our analysis was to compare achievement of clinically significant outc...
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Purpose To review the literature on postoperative corticosteroid injections (CSIs) following primary rotator cuff repair (RCR) to evaluate efficacy and adverse effects. Methods A systematic review of the MEDLINE, EMBASE, and Cochrane databases were performed to identify all studies published within the last 15 years, which reported on outcomes of...
Article
Purpose To determine what subspecialties have applied ML to predict CSO within orthopaedic surgery and to determine whether the performance of these models was acceptable through assessing discrimination and other ML metrics. Methods PubMed, EMBASE, and Cochrane Central Register of Controlled Trials databases were queried for articles that used ML...
Article
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Background: Analyzing outcomes and the minimal clinically important difference (MCID) after anterior cruciate ligament reconstruction (ACLR) is of increased interest in the orthopaedic literature. The purposes of this study were to report outcomes after ACLR at medium to long-term follow-up, identify the threshold preoperative outcome values that...
Article
Background A number of patient-reported outcome measure (PROMs) instruments are used to assess shoulder pain, function, and postoperative satisfaction. Computer adaptive tests (CAT) have been developed in an effort to tailor question delivery, decrease time to completion and floor/ceiling effects, and increase compliance. Previous investigations ha...
Article
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Background Research has identified factors that influence achievement rates of threshold scores on patient-reported outcome measures (PROMs) after hip arthroscopy. However, little data exist on whether failure to achieve a threshold score (minimal clinically important difference [MCID] or substantial clinical benefit [SCB]) in the short term after...
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Purpose To develop and internally validate a machine-learning algorithm to reliably predict cost after anterior cruciate ligament reconstruction (ACLR). Methods A retrospective review of the New York State Ambulatory Surgery and Services database was performed to identify patients who underwent elective ACLR from 2015 to 2016. Features included in...
Article
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Background The association between prolonged postoperative opioid use on outcomes after hip preservation surgery is not known. Purpose To compare minimum 2-year patient-reported outcomes (PROs) between patients who required ≥1 postoperative opioid refill after undergoing hip arthroscopy for femoroacetabular impingement syndrome (FAIS) versus patie...
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Background: Understanding specific risk profiles for each patient and their propensity to experience clinically meaningful improvement after anterior cruciate ligament reconstruction (ACLR) is important for preoperative patient counseling and management of expectations. Purpose: To develop machine learning algorithms to predict achievement of the...
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Background Monthly incidence of elbow ulnar collateral ligament (UCL) injuries and surgeries are relatively unknown. Defining seasonal peaks of UCL injuries and surgeries may identify opportunities for injury prevention strategies. The purpose of this study is to analyze seasonal and monthly variations in UCL injuries and surgeries across the Unite...
Article
Purpose To compare the cost-effectiveness of nonoperative management, particulated juvenile allograft cartilage (PJAC), and matrix-induced autologous chondrocyte implantation (MACI) in the management of patellar chondral lesions. Methods A Markov model was utilized to evaluate cost-effectiveness of three strategies for symptomatic patellar chondra...
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Background The effects of adductor muscle injury on performance in soccer athletes are unknown. Purpose To (1) determine the rate and time to return to play (RTP) after adductor muscle injury, (2) investigate the rate of reinjury after RTP, and (3) investigate any long-term effects of injury on elite soccer player performance. Study Design Cohort...
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There is a paucity of literature on patient-reported outcome measures (PROMs) following proximal hamstring repair beyond return to play, patient satisfaction and pain improvement. The minimal clinically important difference (MCID) defines the minimum degree of quantifiable improvement that a patient can perceive, but the MCID and predictors of this...
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Background: Bilateral leg power is being increasingly investigated as a proxy for the recovery of muscle performance after injury. Functional tests like the single leg hop for distance (SLHD) and single leg vertical jump (SLVJ) are often used to determine symmetry and return to play (RTP) readiness. As an injury predictor, leg power is accurately...
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Purpose To evaluate and compare the Patient-Reported Outcomes Measurement Information System (PROMIS) Physical Function (PF) computerized adaptive test and PROMIS Pain Interference (PI) instruments versus legacy patient-reported outcome measures (PROMs) in patients undergoing hip arthroscopy for femoroacetabular impingement syndrome at 1-year follo...
Article
Background The number of patients requiring reoperation has increased as the volume of hip arthroscopy for femoroacetabular impingement syndrome (FAIS) has increased. The factors most important in determining patients who are likely to require reoperation remain elusive. Purpose To leverage machine learning to better characterize the complex relat...
Article
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Hip arthroscopy is a reproducible and efficacious procedure for the treatment of femoroacetabular impingement syndrome (FAIS). Despite this efficacy, clinical failures are observed, clinical entities are challenging to treat, and revision hip arthroscopy may be required. The most common cause of symptom recurrence after a hip arthroscopy that leads...
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Purpose To evaluate the 1-year outcomes of a small patient series following open gluteus medius/minimus repair with human dermal allograft incorporated into the repair construct using a double-row repair. Methods Data from consecutive patients undergoing a superior gluteal reconstruction for massive, irreparable abductor tendon tears with severe t...
Article
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Objectives Many studies within the recent literature have sought to identify the effect of femoral version and other morphologic characteristics on outcomes after primary hip arthroscopy for femoral acetabular impingement (FAI). In addition to femoral version and combined version, our group has recently begun to use the impingement index to stratif...
Article
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Objectives Fresh osteochondral allograft transplantation (OCA) is an effective method of treating symptomatic cartilage defects of the knee. This cartilage restoration technique involves the single-stage implantation of viable, mature hyaline cartilage into chondral or osteochondral lesion. Predictive models for reaching the clinically meaningful o...
Article
Full-text available
Background: Recent literature has demonstrated conflicting evidence as to whether capsular closure after hip arthroscopy for femoroacetabular impingement syndrome (FAIS) results in superior outcomes compared with capsulotomy without repair. Additionally, these studies have not explored the effect of capsular management on clinically significant out...
Article
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Background: Although minimal clinically important difference (MCID), Patient Acceptable Symptom State (PASS), and substantial clinical benefit (SCB) have been defined for hip-specific legacy patient-reported outcome measures, these metrics have not been defined for the Patient-Reported Outcomes Measurement Information System (PROMIS) instruments f...
Article
Purpose The purpose of our study was to compare lower extremity rotational kinematics and kinetics (angles, torques, and powers) and hip muscle EMG activity between cam-type FAIS and age-sex matched controls during walking, fast walking, stair ascent, stair descent, and sit-to-stand. Methods This study included ten males with unilateral FAIS and t...
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Background Anterior cruciate ligament (ACL) injuries are occurring with increasing frequency in the adolescent population. Outcomes after ACL reconstruction (ACLR) are inconsistently reported in homogeneous patient populations. Purpose/Hypothesis To evaluate outcomes after bone–patellar tendon–bone (BTB) autograft ACLR in competitive high school–a...
Article
Background: Fresh osteochondral allograft transplantation (OCA) is an effective method of treating symptomatic cartilage defects of the knee. This restoration technique involves the single-stage implantation of viable, mature hyaline cartilage into a chondral or osteochondral lesion. The extent to which preoperative imaging and patient factors pre...
Article
Full-text available
The Patient-Reported Outcomes Measurement Information System (PROMIS) Global-10 assesses generic-related quality of life, but has not been well studied in the orthopaedic literature. The purpose was to compare PROMIS Global-10 and legacy hip-specific patient-reported outcome measures (PROMs) in patients undergoing hip arthroscopy for femoroacetabul...
Article
Clinically important outcome assessment has been a point of increasing emphasis in the orthopaedic literature. The minimal clinically important difference, patient acceptable symptom state, and substantial clinical benefit are the most reported in the hip preservation literature. Maximal outcome improvement (MOI) is now also being reported; however...
Article
Full-text available
Purpose The purpose of this study was to preoperatively assess the Patient-Reported Outcomes Measurement Information System (PROMIS) Item Bank v2.0–Mobility in patients with anterior cruciate ligament (ACL) tears to (1) determine construct validity by correlating with legacy patient-reported outcomes (PROs), (2) evaluate test burden, (3) determine...
Article
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Purpose To assess whether pain catastrophizing and kinesiophobia affect return to sport (RTS) or clinically significant outcome (CSO) achievement in patients undergoing hip arthroscopy for the treatment of femoroacetabular impingement (FAI). Methods Patients undergoing primary hip arthroscopy at a single institution between January 2017 and March...
Article
Purpose: To (1) report on pre- and post-operative patient reported outcome (PROs) scores for repeat revision patients in short-term follow up and (2) compare minimal clinically important difference (MCID) and patient acceptable symptomatic state (PASS) achievement between primary, revision, and repeat revision hip arthroscopy cohorts. Methods: D...
Article
Artificial intelligence (AI) represents the fourth industrial revolution and the next frontier in medicine poised to transform the field of orthopaedics and sports medicine, though widespread understanding of the fundamental principles and adoption of applications remain nascent. Recent research efforts into implementation of AI in the field of ort...
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Despite lack of clear understanding, the use of biologic treatment methods has increased in the United States. Therapeutic methods, including platelet-rich plasma (PRP), bone marrow aspirate concentrate (BMAC) and hyaluronic acid (HA) among other biologics, are commonly associated with relief of pain in a number of different orthopedic conditions....
Article
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Background Open repair for gluteus medius and minimus tears is a common surgical treatment for patients with lateral hip pain associated with abductor tears; however, clinically meaningful outcomes have not been described after open surgical treatment. Purpose To define the minimal clinically important difference (MCID) in patient-reported outcome...
Article
Background: Despite previous reports of improvements for athletes following hip arthroscopy for femoroacetabular impingement syndrome (FAIS), many do not achieve clinically relevant outcomes. The purpose of this study was to develop machine learning algorithms capable of providing patient-specific predictions of which athletes will derive clinical...
Article
Advances in hip preservation surgery have to lead to increased utilization of hip arthroscopy. With this, there has also been a growth in the understanding of various hip conditions, therefore, leading to an increase in hip conditions amenable to arthroscopic intervention. The acetabular hip labrum has been at the forefront of arthroscopic advances...
Article
Purpose To compare the impact of age and gender on achieving meaningful outcomes among minimum patients 5-years after undergoing hip arthroscopy for femoroacetabular impingement syndrome (FAIS). Methods Consecutive patients undergoing hip arthroscopy for FAIS by a single fellowship trained surgeon between 1/2012 and 10/2014 were analyzed. Study in...
Article
The use of telehealth as a means of evaluating and treating patients with orthopedic conditions has become widespread across multiple institutions and countries. Although this trend was largely a result of physical distancing requirements as a way to mitigate the risk of COVID-19 transmission, many have come to observe several benefits of telehealt...
Article
Background: Fresh osteochondral allograft transplantation (OCA) is an effective method of treating symptomatic cartilage defects of the knee. This cartilage restoration technique involves the single-stage implantation of viable, mature hyaline cartilage into the chondral or osteochondral lesion. Predictive models for reaching the clinically meanin...
Article
Purpose To 1) compare the rates of reaching threshold hip-specific outcome scores for achieving the minimal clinically important difference (MCID) and Patient Acceptable Symptomatic State (PASS) between patients who had partial vs complete T-capsulotomy repair, and 2) identify the failure rates in each group 5-years after undergoing hip arthroscopy...
Article
Purpose To evaluate the quality of orthopaedic cost-effectiveness analyses (CEAs) in accordance with the 2016 recommendations by the Second Panel on Cost-Effectiveness in Health and Medicine. Methods A systematic review of all CEAs from 9/2017-9/2019 in the ten highest impact orthopaedic surgery journals was performed. Quality scoring utilized the...
Article
Introduction: This study aimed to assess the quality of online resources pertaining to cannabidiol (CBD) for the nonoperative management of hip and knee arthritis. Methods: Websites were identified on the three most popular global search engines using terms relevant to CBD, hip or knee pain, and arthritis. Websites were scored based on a 25-poin...
Article
Purpose: To (1) develop and validate a machine learning algorithm to predict clinically significant functional improvements after hip arthroscopy for femoroacetabular impingement syndrome (FAIS) and to (2) develop a digital application capable of providing patients with individual risk profiles to determine their propensity to gain clinically signi...