Benay SEZER TUNÇSOY

• PhD
• Professor (Associate) at Adana Science and Technology University

Insect growth regulators and microbial insecticides are mostly used in pest management since they are nontoxic to other organisms and have short half-life in the environment. Effects of juvenile hormone analogue pyriproxyfen and Bacillus thuringiensis on antioxidant enzyme (catalase (CAT), superoxide dismutase (SOD) and glutathione peroxidase (GPx)...

Silver nanoparticles (Ag NPs) have been used in many studies due to their inhibitory properties on microorganisms such as bacteria and viruses. In recent years, due to global problems such as environmental pollution, the green synthesis (biosynthesis) method is frequently preferred because it is simple and low cost and does not require the use of t...

Studies on heavy metal toxicity show that toxicity of nanoparticles compared to micro form have hypothesis regarding nanoparticles are more efficient on the oxidative stress. The aim of the study was to compare the toxic effects of nano and micro particles of Al2O3 and tissue differences on oxidative stress using model organism Galleria mellonella...

Nanomaterials of different sizes and diameters are frequently used in various industrial areas, due to the rapid development of nanotechnology. Hence, it leads to toxic effects on the environment and non-target organisms. Due to the increasing use of nanotechnology in the industrial field, it is inevitable that the rate of release of engineered and...

The effects of Cu, Zn and their mixture on bioaccumulation and antioxidant enzyme activities of midgut and fat body of Galleria mellonella larvae were investigated. Exposure to mixtures of both metals showed a synergistic effect and the accumulation levels were increased in both tissues. When the metals were exposed separately the concentration of...

Nanoparticles (NPs) are now being used in many industrial activities, such as mining, paint and glass industries. The frequent industrial use of NPs contributes to environmental pollution and may cause cellular and oxidative damage in native organisms. In this study, the toxic effects of titanium dioxide nanoparticles (TiO2 NPs) were investigated u...

In this study, the effects of dietary CuO nanoparticles (NPs) on metabolic enzyme activity, biochemical parameters, and total (THC) and differential hemocyte counts (DHC) were determined in Galleria mellonella larvae. Using concentrations of 10, 100, 1000 mg/L and the LC10 and LC30 levels of CuO NPs, we determined that the NPs negatively impacted m...

The effects of Cu, Zn and their mixture on bioaccumulation and antioxidant enzyme activities of midgut and fat body of Galleria mellonella larvae were investigated. The application of metals as a mixture showed a synergistic effect and the accumulation levels were increased in both tissues. Zn accumulation increased in midgut and fat body of G. mel...

Plant-parasitic nematodes are important pests causing economically high yield losses in plants cultivated worldwide. Plant-parasitic nematodes damage the host plant by causing wounds on the plant roots and some microbial diseases, forming brown spots on the root and swelling or rotting of the tubers on the above-ground parts of the plant. In agricu...

Nanomaterials of different sizes and diameters are frequently used in various industrial areas, due to the rapid development of nanotechnology. Hence, it leads to toxic effects on the environment and non-target organisms, and adverse effects such as oxidative stress and membrane damage in cells and tissues are occurred. Some biomarkers such as the...

Yapılan çalışmada farklı derişimlerdeki bakır oksit nanopartiküllerinin (10, 100 ve 1000 µg/mL) Galleria mellonella larvalarının orta barsak ve yağ dokusundaki katalaz (CAT), superoksit dismutaz (SOD), glutatyon peroksidaz (GPx), glutatyon-s-transferaz (GST) ve asetilkolinesteraz (AChE) aktiviteleri üzerine etkileri araştırılmıştır. Farklı derişiml...

With the increasing uses of biological control methods, knowing the physiological and immunological effects of these insecticides on insects is essential for them to be used safely in agricultural areas. The aim of the study is to determine the effects of pyriproxyfen and Bacillus thuringiensis subsp. kurstaki individually and as a mixture on malon...

Insect growth regulators and microbial insecticides are frequently used in agricultural fields for pest management. Therefore, resistance development occurs in pests against both insecticide types. In recent years, the use of insecticides with a different mode of action in mixture against resistance development has been accepted as a frequently pre...

Beauveria bassiana, which is used for this experiment in order to determine the effects on Galleria mellonella and its parasitoid Trichogrammacacoeciae, is a naturally occurring pathogens and have been used to control insect pest.The conidia of the fungi germinate on the surface of the insect host, penetrate through the cuticle, spread in the hemol...

Böcek büyüme düzenleyicileri ve mikrobiyal insektisitler zararlılarla mücadelede tarımsal alanlarda sıklıkla kullanılmaktadır. Bu nedenle, her iki insektisit türüne karşı zararlılarda direnç gelişimi meydana gelmektedir. Son yıllarda, direnç gelişimine karşı farklı etki mekanizmalı insektisitlerin karışım halinde uygulanması sıklıkla tercih edilen...

Nanoteknoloji, günümüzde hızlı bir şekilde gelişmekte ve nanopartiküller kozmetik, eczacılık, gıda, endüstriyel ürünler, boya, elektronik, giyim gibi çok geniş ve farklı alanlarda kullanılmaktadır. Bu geniş uygulama alanları sonucunda nanopartiküller küçük boyutları ve kendine özgü diğer özelliklerinden dolayı insan sağlığı, biyoçeşitlilik, çevre v...

Bu araştırmada bakır oksit nanopartiküllerinin (CuO NP) LD50 konsantrasyonunun etkisinde Galleria mellonella larvalarının orta barsak ve yağ dokularındaki protein, glikojen ve lipit miktarları ile immun sistemde önemli bir parameter olan total hemosit sayısı üzerine etkilerinin belirlenmesi amaçlanmıştır. CuO NP’ nin G. mellonella orta barsak ve ya...

Toxic effects of Zn (30 mg / L) and Cu (10mg / L) applied singly and in mixture were investigated on the total and differential hemocyte counts of Galleria mellonella larvae. Five types of hemocytes were observed in G. mellonella larvae; prohemocytes, granulocytes, plasmatocytes, spherulocytes and eunocytoids. Total hemocyte count (THC) decreased w...

Effects of copper oxide nanoparticles (CuO NPs) were investigated in the midgut and fat body of Galleria mellonella. Fourth instar larvae were exposed to 10 µg Cu/L of CuO until becoming last instar larvae, and catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GPx), glutathione-s-transferase (GST) and acetylcholinesterase (AChE) a...

The rapid development of nanomaterials in various fields of science results in being in need of understanding their toxic effects on development and physiology of non-target organisms and environment. Increased production and widespread use of these nanomaterials led to their release into the environment; nevertheless, the knowledge of their behavi...

This study analyzes the effect of protein, carbohydrate and tannic acid in artificial diet on the survival of Vanessa atalanta larvae infected by Bacillus thuringiensis subsp. kurstaki by using seven different artificial diets. The highest survival rate among the larvae infected by Bacillus thuringiensis kurstaki (Btk) was obtained from the larvae...

This study was examined the changes in catalase (CAT), glutathione peroxidase (GPx) and superoxide dismutase (SOD) enzymes and total hemocyte in hemolymph of Bacillus thuringiensis subsp. kurstaki infecting Hyphantria cunea Drury (Lepidoptera: Arctiidae) larvae fed with gallic acid and some heavy metals (Ni, Zn and Cu) added artificial diets. This...

The synergistic effects that occur on catalase (CAT), glutathione peroxidase (GPx) and superoxide dismutase (SOD) enzymes and total hemocyte count when Hyphantria cunea Drury (Lepidoptera: Arctiidae) larvae infected with Bacillus thuringiensis subsp. kurstaki were fed with artificial diets prepared by adding tannic acid and some heavy metals (Ni, Z...

Heavy metals can have harmful effects not only on the survival, growth, reproduction and metabolism of animals but also on the innate immune system. It is known that the innate immune system of invertebrates which plays a critical role in protecting the body from infections, shares a high degree of homology with that of mammals. Therefore, many inv...

Nanoparticles (NPs) are increasingly being used in biological and medical area. Therefore, their potential toxic effects resulting from use or unintentional release into environment. Metal-containing NPs comprises the largest number of NPs, which includes oxides such as zinc oxide (ZnO), titanium dioxide (TiO2), cerium dioxide (CeO2), copper oxide...

Effects of pyriproxyfen and Bacillus thuringiensis on Galleria mellonella larvae applied singly and in mixture, antioxidant defense system in hemolymph, midgut and fat body, on acetylcholinesterase activity was investigated. The aim of this study is to find a solution to the resistance developed against B. thuringiensis and to find a rapid and reli...

Effects of pyriproxyfen and Bacillus thuringiensis on Galleria mellonella larvae applied singly and in mixture, antioxidant defense system in hemolymph, midgut and fat body, on acetylcholinesterase activity was investigated. The aim of this study is to find a solution to the resistance developed against B. thuringiensis and to find a rapid and reli...

Insect growth regulators are mostly used in pest management since they are non toxic to other organisms and have short half life in the environment. Effects of juvenile hormone analogue, pyriproxyfen on catalse (CAT) and superoxide dismustase (SOD) activity of Galleria mellonella was investigated. Larvae were exposed to 0.0001; 0.0005; 0.001 and 0....

The effects of juvenile hormone analogue pyriproxyfen on total hemocyte count and hemocyte morphology of Galleria mellonella pupae were investigated. Pyriproxyfen was applied to last instar larvae of G. mellonella topically on the dorsal thorax. Five hemocyte types; prohemocytes, plasmotocyte, granulocyte, spherule cells and oenocytoids were identi...

Effects of pyriproxyfen and Bacillus thuringiensis on midgut antioxidant enzymes (SOD, CAT, GPx) and lipid peroxidation (MDA) levels of Galleria mellonella larvae were studied by applying these insecticides singly and in mixture. Chemical insecticides that are used for the management of G. mellonella have some toxic effects on non-target organisms...

Amaç: Bitkisel kökenli bir insektisit olan azadirachtinin zararlı böcek türlerine karşı uzaklaştırıcı, beslenmeyi önleyici, üreme ve yumurta verimliliğini azaltıcı etkileri bulunmaktadır. Ayrıca böceklerin deri değiştirme mekanizmasının bozulmasına da yol açmaktadır. Büyük bal mumu güvesi Galleria mellonella bal peteklerine zarar veren Lepidopte...

Amaç: Biyolojik mücadele kapsamında kullanılan juvenil hormon analoglarından pyriproxyfenin 0.10, 0.50, 1.00, ve 5.00 ppm konsantrasyonlarının Galleria mellonella L. larvalarında reaktif oksijen türevlerine karşı oluşabilecek antioksidan enzimlerinden katalaz ve süperoksit dismutaz aktiviteleri üzerine etkisi araştırılmıştır. Gereçler ve Yönteml...

The most active ingredient against insects, azadirachtin, a tetranortriterpenoid, manifests antifeedant, growth regulatory and fecundity-reducing properties in insects. Effects of azadirachtin extracts obtained from ripe fruits, seeds, trunk and flower of Melia azedarach and Azadirachta indica on total glycogen amount of Galleria mellonella was stu...

Kimyasal savaşımın hedef olmayan türlere ve doğal düşmanlara, çevre kirliliği, doğal dengenin bozulması ve zararlı türlerde direnç oluşumu gibi pek çok yan etkisi bulunmaktadır. Bu nedenle hem ekonomik hem de çevreye zarar vermeyen yöntemlerin geliştirilmesi hedeflenmektedir. Bu amaçla feromon tuzakları, kısırlaştırma yöntemi, düşman böcek salı...

Azadirachta indica (Meliaceae)’ dan ekstrakte edilmiş azadirachtin etkin maddesi, birçok böceğin biyolojik kontrolü için yüksek etki gösteren bitkisel insektisitler arasındadır. Böcekler üzerinde yapılan denemelerde azadirachtinin beslenmeyi, büyüme ve gelişmeyi engellediği, üreme davranışları ve yumurta olgunlaşmasını olumsuz yönde etkilediği bili...

The most active ingredient against insects, azadirachtin, a tetranortriterpenoid, manifests antifeedant, growth regulatory and fecundity-reducing properties in insects. Effects of azadirachtin extracts obtained from ripe fruits, seeds, trunk and flower of Melia azedarach and Azadirachta indica on total glycogen amount of Galleria mellonella was stu...

In this study, the effects of azadirachtin extract obtained from the kernels of ripe fruits, leaves, stems and flowers from Melia azedarach and Azadirachta indica were investigated on the glycogen and protein contents of Galleria mellonella L. larvae. Azadirachtin caused a reduction in protein and glycogen contents when 1.00, 2.00, 4.00 and 6.00 ml...