Behnam Mahdavi

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Verified

Behnam verified their affiliation via an institutional email.

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• PhD in Phytochemistry
• Professor (Associate) at Hakim Sabzevari University

Background: Rosa foetida is a popular plant in Iran due to its various medicinal applications. Objectives: In the present study, the essential oil of R. foetida flowers was isolated to identify the chemical composition and evaluate the anti-oral cancer and antioxidant activity of the plant extract. Methods: The essential oil was extracted using the...

In this study, a magnetic carboxymethylated β-cyclodextrin (Mag/CM-β-CD) was developed as a carrier system to assess its capability on drug delivery application by forming an inclusion complex with amantadine (Amn) as a drug model. The synthesized inclusion complex (Mag/CM-β-CD/Amn) was analyzed using various techniques, including FT-IR, XRD, BET,...

This study was conducted to optimize the reaction conditions based on the solubility percentage of carboxymethyl NMG by monochloroacetic acid (MCA) in the presence of sodium hydroxide (alkaline environment). The effect of various reaction parameters (pH, MCA concentration, and temperature) on the solubility of NFG was evaluated. The highest solubil...

In this research, the extract of Ephedra intermedia Schrenk &C.A.Mey was encapsulated using the mini‐emulsion polymerization method based on methyl methacrylate polymers with a nanometer size. The encapsulated extract was characterized using different analytical techniques. Furthermore, the loading efficiency and release of the plant extract were e...

Carbon quantum dots (CQDs), the newest member of carbonaceous nanomaterials, have drawn many considerations since the past two decades. A vast number of researchers made their efforts to demystify optical behavior of these materials despite being demanding. Nevertheless, their emission origin is still a controversial issue and this area suffers fro...

Cannabis sativa L. has been recognised as a narcotic drug in different parts of the world. The current report deals with the screening of the chemical profiles of the essential oils (EOs) and volatiles obtained from the aerial ports of Cannabis sativa L. (APCS) using classical hydrodistillation (HD), solid phase microextraction (SPME) along with a...

Eye retinopathy means damage to the retina of the eye, which can have various causes, both congenital and acquired. Diabetes is one of the important causes of eye retinopathy. Retinopathy can develop slowly or quickly, get better on its own, or lead to permanent damage. No treatment is recommended in the early and mild stages. However, close monito...

In this work, an innovative biogenic technique was employed to synthesize palladium nanoparticles (Pd-NPs) using propolis. Characterization of the crystal structure and morphology of the prepared NPs was performed using transmission electron microscopy (TEM), UV-Vis spectroscopy (UV-Vis), particle-size distribution and X-ray diffraction (XRD) analy...

The production of ammonia as an important raw material in the chemical, agricultural, and food industries has been always a significant concern. However, conventional ammonia production methods require high energy consumption and costs. The photocatalytic rotes use green light sources and cost-effective photocatalysts to obtain ammonia from water u...

In the present report, a combination of classical and advanced methods, namely classical hydrodistillation (HD) and solvent free microwave extraction (SFME) have been used for the extraction of essential oils from flowers, leaves and stems of Perovskia abrotanoides Karel. as an endemic plant to Golestan Province, Iran. The volatile fractions from t...

In this work, an environmentally friendly strategy was used to synthesize gold nanoparticles (Au NPs) using Olea europaea (olive) fruit. Transmission electron microscopy (TEM), UV-Vis spectroscopy, X-ray diffraction (XRD) and energy-dispersive X-ray (EDX) were used to characterize the physicochemical properties of the synthesized NPs. An Au NPs mod...

The optoelectronic properties of pyrazinamide (PZA) in a monoclinic crystal structure were investigated by the full potential linear augmented plane wave (FP-LAPW) method. The Perdew-Burke-Ernzerhof generalized gradient approximation (PBE-GGA) and the Tran-Blaha modified Becke Johnson (TB-mBJ) potential were applied to calculate exchange correlatio...

Nanocomposites have gained attention due to their variety of applications in different fields. In this research, we have reported a green synthesis of a bi-metallic nanocomposite of nickel and zinc using an aqueous extract of Citrus sinensis in the presence of chitosan (Ni/Zn@orange/chitosan). The nanocomposite was characterized using different tec...

Since the emergence of carbon quantum dots (CQDs), they have attracted much considerations because of their potential applicability in myriad industries. Innumerable efforts have been made to demystify the mysterious world of CQDs from physicochemical view point. In the present work, CQDs were synthesized via a thermal decomposition method followin...

Context: The global reactivity and molecular stability of sertraline hydrochloride (SHCl) are predicted for chemical and photo-biological applications. SHCl has a wide indirect HOMO-LUMO gap of about 4.77 eV. The p orbital states of nitrogen and chlorine atoms play the main role in HOMO and LUMO energy levels. Maximum optical transitions are obser...

In the present study, tin nanoparticles were green‐synthesized using the aqueous extract of Foeniculum vulgare leaf aqueous extract. The synthesized SnNPs (tin nanoparticles) were characterized by analytical techniques including EDX (energy dispersive X‐ray), FE‐SEM (field emission scanning electron microscopy), XRD (X‐ray diffraction), UV–vis and...

Background: In addition to current therapies, herbal medicine is still used as an effective method for the treatment of some diseases such as bleeding disorders. Thymus vulgaris has been employed as traditional remedy in the treatment of bleeding disorders, although its clinical effects have not been investigated yet. Accordingly, this study evalua...

Euphorbia is one of the six largest genera of flowering plants. The Euphorbia species are widely distributed throughout the world. So, the aim of this study was to investigate the phenolic compounds profile, antioxidant activity, cytotoxicity, and apoptosis induction of Euphorbia. granulata extract (EGE) on breast cancer cells. In this experiment,...

The aim of the present study was to magnetize Plantago ovata Forssk. hydrogel and produce a nanosphere system to carrier mefenamic acid as the drug model. For this propose, P. ovata seeds hydrogel (POSH) was extracted and magnetized by Fe3O4 being functionalized using tetraethyl orthosilicate and trimethoxyvinysilane. Thereafter, mefenamic acid (MF...

A mild and efficient green protocol has been disclosed for tiny Pd NPs fabricated chitosan-pectin composite functionalized Kaolin ([email protected]/Pd). The post-synthetically modified biogenic material was characterized over a number of physicochemical methods like, FE-SEM, TEM, EDX, elemental mapping, XRD and ICP-OES. Catalytic efficiency of the...

We now report the utilization of nanocomposite Fe3O4@GO-NH as an efficient and easilyseparable heterogeneous catalyst in the three-component synthesis of 2-aminochromenes.

Introduction Many nanoparticles have pharmacological and biochemical properties, including antioxidant and anti-‎inflammatory properties, which appear to be involved in anticarcinogenic and antimutagenic activities. In the recent study, nickel nanoparticles were green-synthesized using the Alhagi sparsifolia leaf aqueous ‎extract. ‎ Material and m...

Introduction Recently, various nanoparticles containing medicinal plants have been specifically designed to deliver anticancer drugs and nucleic acids such as DNA and RNA to cancer cells and as a result, they open up new avenues in cancer treatment strategies. In this study, gold nanoparticles were synthesized in aqueous medium using Nigella damasc...

Introduction The present study investigated the anti-acute myeloid leukemia effects of Ziziphora clinopodides Lam leaf aqueous extract conjugated cadmium nanoparticles. Material and methods To synthesize CdNPs, Z. clinopodides aqueous extract was mixed with Cd(NO3)2 .4H2O. The characterization of the biosynthesized cadmium nanoparticles was carrie...

Introduction The biosynthesis of metal nanoparticles using medicinal plants is not only economical but also environmentally friendly as well as having miscellaneous biomedical applications. In the present study, silver nanoparticles were green-synthesized using the aqueous extract of Calendula officinalis. Material and methods The synthesized AgNP...

Herein, a comprehensive review is given focusing on the chemical profiles of the essential oils (EOs), non-volatile compounds, ethnobotany, and biological activities of different Haplophyllum (Rutaceae family) species. To gather the relevant data, all the scientific databases, including Scopus, ISI-WOS (Institute of Scientific Information-Web of Sc...

Herein, the chemical profiles of the essential oils and volatiles obtained from the aerial parts of Mentha pulegium L. (Lamiaceae) are reported respectively using microwave-assisted hydrodistillation (MAHD) and headspace solid phase microextraction (HS-SPME) approaches associated to gas chromatography-mass spectrometric (GC-MS) quantification. Usin...

Nowadays, researchers pay a vast deal of attention to neural tissue regeneration due to its tremendous effect on the patient's life. There are many strategies, from using conventional autologous nerve grafts to the newly developed methods for reconstructing damaged nerves. Among the various therapeutic methods, incorporating highly potent biomolecu...

Tanacetum fisherae Aitch. & Hemsl. is an endemic plant growing wild in some brackish regions of Iran. Since there are not enough reports concerning the quantitative and qualitative analyses of its essential oil, it was decided to characterise the respective water-distilled oils obtained from the flowers and leaves of this medicinal plant. Character...

In recent years, the biosynthesized of metallic nanoparticles has been rapidly growing due to their environmentally synthesis and widespread applications in science and industry. In this study, we have reported the green synthesis of NiONPs using an aqueous extract of Trigonella subenervis (NiONPs@TS). The nanoparticles were characterized by Fourie...

Undoubtedly, identification of the chemical composition of organic extracts or secondary metabolites of plant materials and evaluation of their potential bioactivity are among the main objectives of natural products-based investigations. In the present study, we report the chemical composition and antidiabetic activity of Sophora pachycarpa (Family...

Aloysia Paláu is an important herbal genus from the Verbenaceae family and possesses numerous remedial properties in the folk medicine of Asian, European, and, in particular, South American countries. Only a few reports have discussed some phytochemical characteristics associated with Aloysia species. Right the lack of an exhaustive report prompted...

In this study, nickel nanoparticles (NiONPs) have been successfully synthesized in an aqueous medium using the aqueous extract from the leaves of Calendula officinalis. The synthesized NiONPs were characterized using different techniques. According to the XRD analysis, the mean crystal size for NiONPs was found to be 33.17 nm. In addition, SEM imag...

Doxepin hydrochloride is an antidepressant drug commonly used to treat mild to moderate depression. However, this drug has poor oral bioavailability, with the percentage of drug that can enter the bloodstream being weak and variable. The present study seeks to investigate the ZIF-8 nanoparticles for doxepin delivery and to assess this drug uptake a...

Linum usitatissimum is a candidate as a remedy to treat prostate problems in some folklore medicines. In this study, we have reported the phenolic and flavonoid constituents, antioxidant activity, and potential of the plant extract against prostate cancer cells. The phenolic and flavonoid compound profile of the extract were established using HPLC...

Editor's Note: this Article has been retracted; the Retraction Note is available at https://www.nature.com/articles/s41598-020-71843-9

Etlingera sayapensis belongs to Zingiberaceae family. This research tried to evaluate the chemical composition and bioactivity of E. sayapensis fruits essential oil (ESFO) and its methanolic extract (ES-FM). The essential oil was obtained using a Clevenger-type apparatus. ESFO composition was identified by chromatographic-based methods (GC/FID and...

The aim of the experiment was a green synthesis of cobalt nanoparticles from the aqueous extract of Ziziphora clinopodioides Lam (CoNPs) and assessment of their cytotoxicity, antioxidant, antifungal, antibacterial, and cutaneous wound healing properties. The synthesized CoNPs were characterized using different techniques including UV–Vis., FT-IR sp...

In the synthesis of organic compounds, heterogeneous catalysts have gained significance versus their homogeneous counterparts, due to both environmental and economic concerns. 1–4 Homogeneous catalytic systems cannot as readily be commercialized owing to difficulties encountered with equipment corrosion, solvent recycling, isolation, and reusabilit...

In this study, the anti-acute myeloid leukemia (AML) effects of Ziziphora clinopodioides Lam leaf aqueous extract conjugated cadmium nanoparticles (CdNPs) were compared with daunorubicin as a common chemotherapeutic drug. To synthesize CdNPs, Z. clinopodioides aqueous extract was combined with Cd(NO 3 ) 2 .4H 2 O. For analyzing CdNPs, SEM, UV-Vis....

Background This research tried to evaluate the chemical composition of the essential oil of Salvia limbata, and also bioactivity of essential oil and the plant extract. S. limbata is an aromatic plant with medicinal uses such as analgesic, anti-inflammatory activities. Methods The essential oils of the flowers of Salvia limbata were obtained using...

The therapeutic properties of tin nanoparticles have been proved in recent years. One of their probable effects is anti‐anemia. In this study, tin nanoparticles were synthesized and characterized in aqueous medium using Ziziphora clinopodioides Lam leaf aqueous extract as the reducing and stabilizing agent. We also assessed the antihemolytic anemia...

Gallic acid (GA) and its benzamide derivatives have a wide variety of biological activities, such as antimicrobial, antioxidant, anticancer. In this study, we have reported the synthesis of some new hybrid compounds comprised of the 2-aminothiophene and GA moieties and evaluation of their cytotoxic activities against HeLa (cervical cancer), HCT116...

We report the chemical composition and bioactivity of flowers essential oil of Ephedra intermedia (EIO) for the first time. The essential oil was obtained using a Clevenger-type apparatus. The essential oil composition was identified by chromatography methods. The minimum inhibitory concentration method (MIC) was chosen to investigate antibacterial...

In recent decades, nanotechnology is growing rapidly owing to its widespread application in medical science. The aim of the experiment was the evaluation of cytotoxicity, antioxidant, antibacterial, antifungal, and cutaneous wound healing activities of green synthesized manganese nanoparticles using Ziziphora clinopodioides Lam leaves (MnNPs@ZC). T...

β-Cyclodextrin (β-CD) is a versatile and naturally occurring host which strongly binds adamantane and its derivatives. Based on this binding, we prepared a host–guest inclusion complex of β-CD with adamantane, and selectively iodinated the included adamantane to 1-iodoadamantane by iodoform. The only formed monoiodo product confirmed our initial as...

LamZiziphora clinopodioides Biosynthesis of metal nanoparticles using plant medicine is under exploration is due to wide biomedica applications and research interest in nanotechnology, the recent study was assessing green synthesis of zinc nanoparticle using ), the use of plant material Ziziphoraleaves extract (ZnNPs@ not only makes the process eco...

In recent decades, nanotechnology is growing rapidly owing to its widespread application in science and industry. The aim of the experiment was chemical characterization and evaluation of cytotoxicity, antioxidant, antibacterial, antifungal, and cutaneous wound healing activities of titanium nanoparticles using aqueous extract of Ziziphora clinopod...

In recent decades, nanotechnology is growing rapidly owing to its widespread application in science and industry. The aim of the experiment was chemical characterization and evaluation of cytotoxicity, antioxidant, antibacterial, antifungal, and cutaneous wound healing activities of titanium nanoparticles using aqueous extract of Ziziphora clinopod...

Objective To report the chemical composition and bioactivity (including antioxidantand antimicrobial activity, hemolytic activities, and cytotoxicity) of flowers essential oil from Matricariachamomillavar. chamomilla(MCCO) for the first time. Methods The essential oil was obtained using a Clevenger-type apparatus. Then, the essential oils composit...

In the present work, nano-particles of potassium-substituted hydroxyapatite with formula of (Ca2.94K2.06)(PO4)0.94(CO3)2.06(OH) (KHA) are reported showing effective adsorption of Congo red dye in the room temperature. Synthesized sol–gel-derived KHA was identified by XRD, FTIR, TGA/DTA, and EDXA analyses. Moreover, the size of nano-particles and mi...

Purpose The purpose of this paper is synthesis and evaluation of antioxidant and antibacterial activities of a series of new azo dyes derived from 4-aminostilbene. Design/methodology/approach First, the starting material 4-aminostilbene was prepared via two successive Wittig and reduction reactions from 4-nitrobenzyl bromide. The obtained 4-amin...

Gallic acid (GA), as a main phenolic acid, has been considered the main player on the human health, including the effects of reduction of cholesterol, depression of hypertension, anti-oxidation, anti-microbial, protection against cardiovascular disease and cancer. This study describes the development, electrochemical characterization and utilizatio...

The fresh and dried leaves of Etlingera brevilabrum were pyrolyzed and burned in a fluidized-bed reactor under atmospheric nitrogen and air, respectively, at different temperatures. The collected smoke from each experiment, which was condensed as a liquid, was analyzed using GC-MS. The chemical compositions of the smoke liquids were rich in phenoli...

The rhizomes, stems and leaves of Etlingera sayapensis were extracted with ethyl acetate, acetone, ethanol and methanol to give 12 extracts. The total phenolic content (TPC) of the extracts was measured in this study, together with their antioxidant activity. Assays used were radical scavenging activity (RSA), β-carotene bleaching (BCB), ferrous io...

Here, a green method is described for the biosynthesis of Ag nanoparticles (Ag NPs) using aqueous extracts of the leaf of Salvia leriifolia as reducing and stabilizing agent. Various techniques such as scanning electron microscopy (SEM), atomic force microscopy (AFM), transmission electron microscopy (TEM) and X-ray diffraction (XRD) were employed...

Objective: To report the chemical composition and bioactivity (including antioxidant and antimicrobial activity) of essential oils from the rhizomes, stems, and leaves of Etlingera sayapensis (E. sayapensis) A.D. Poulsen & Ibrahim for the first time. Methods: First, the essential oils were obtained using a Clevenger-type apparatus. Then, the ess...

In the present study, we have reported the total phenolic content, total flavonoid content, antioxidant and antimicrobial activity of aerial parts of Salvia leriifolia extracts and

Volatile oils obtained by hyrodistillation (HD) and solvent free microwave extraction (SFME) from the aerial parts of Ferula gummosa (Apiaceae) were analyzed by means of GC and GC-MS. A total of forty two compounds were identified in the hyrodistilled oil accounting for 96.5 % of the oil, of which γ-elemene (14.1 %), germacrene B (11.8 %), (E)-γ-bi...

KEYWORDS Sclerorhachis platyrachis GC/MS β-pinene γ-terpinene Antioxidant activity ABSTRACT: In this study, the essential oil obtained by hydrodistillation of the aerial parts of Sclerorhachis platyrachis (Boiss.) Podlech ex Rech. f. (Compositae), growing wild in Sabzevar, Khorasan Razavi Province (Iran), was analyzed by GC and GC/MS. The total yie...

Essential oils from fresh parts of Etlingera brevilabrum Valeton (Zingiberaceae) including rhizome, stolon, stem, and leaves were hydrodistilled, and studied for their chemical composition, antioxidant, and antibacterial activity. Characterization by GC-FID and GC-MS showed monoterpene hydrocarbons dominated the oils of the leaves and stems (57.3 a...

In this study, the essential oil obtained by hydrodistillation of the seed of Trachyspermum ammi (Umbelliferae), growing wild in Sabzevar, Khorasan Razavi province (Iran), were analyzed by GC and GC/MS. The yield of total volatiles was 2.3% (w/w). Forty four compounds representing 91.6% of the aerial parts oil were identified. The main components o...

To isolate the chemical constituents from the leaves and stems of Etlingera brevilabrum, the plant parts were firstly extracted by n-hexane. Then the extracts were purified using different chromatography methods such as vacuum liquid chromatography, column chromatography, and preparative thin layer chromatography. Finally tow compounds were isolate...

In this study, the essential oil obtained by hydrodistillation of the seed of Trachyspermum ammi (Umbelliferae), growing wild in Sabzevar, Khorasan Razavi province (Iran), were analyzed by GC and GC/MS. The yield of total volatiles was 2.3% (w/w). Forty four compounds representing 91.6% of the aerial parts oil were identified. The main component...

The essential oils isolated from aerial parts of Eryngium bungei Bioss. by hydrodistillation (HD), microwave-assisted hydrodistillation (MWHD) and head space solid-phase microextraction (HS-SPME) techniques, were analyzed by means of GC and GC-MS methods. The main components of the water distilled oil were found to be borneol (44.4 %), isobornyl fo...

Acid-catalyzed cyclocondensation of2-chloroacetic acid and 2-chloropropionic acid with some substituted o-phenylenediamines afforded the corresponding 2-(1-chloroalkyl)benzimidazoles. Upon treatment with hydrazine hydrate, in order to obtain hydrazine-containing compounds as suitable precursors for construction of new heterocyclic systems, the l...

The base, stem and leaves of Etlingera brevilabrum were extracted consecutively with hexane, ethyl acetate, acetone, methanol, methanol:water (1:1) and water and also solely with ethanol. The total phenolic content and antioxidant assays of DPPH radical scavenging activity, b-carotene bleaching, ferrous ion chelating ability and reducing power were...

Phenyl fatty hydroxamic acids (PFHAs) were synthesized by phenyl hydroxylaminolysis of canola or palm kernel oils using lipozyme TL IM as catalyst. Copper complexes of phenyl fatty hydroxamic acids (copper phenyl fatty hydroxamate (Cu-PFHs)) acids were prepared by stirring the phenyl fatty hydroxamic acids which were dissolved in hexane and copper(...

Disc diffusion (DD), minimum inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) assays were used to evaluate the antimicrobial activity of 21 consecutive extracts of different aerial parts of Etlingera brevilabrum against 18 microorganisms that included six Gram-positive [(+)], ten Gram-negative [(-)] bacteria and two fungi...

Liquid-liquid iron(III) extraction was investigated using benzyl fatty hydroxamic acids (BFHAs) and methyl fatty hydroxamic acids (MFHAs) as chelating agents through the formation of iron(III) methyl fatty hydroxamate (Fe-MFHs) or iron(III) benzyl fatty hydroxamate (Fe-BFHs) in the organic phase. The results obtained under optimized conditions, sho...

Essential oil from the air-dried rhizomes, stems and leaves of Etlingera brevilabrum were hydrodistilled using a Clevenger-type apparatus and identified by GC and GC-MS. Monoterpene hydrocarbons dominated the oils from the stems and leaves (66.8 and 89.8% respectively) whereas oxygenated monoterpenes were dominant in the rhizomes (40.2 %). Eucalypt...

Phenyl fatty hydroxamic acids (PFHAs) were synthesized in a biphasic organic/aqueous medium from canola oil and phenyl hydroxylamine (PHA). The reaction was carried out in a sealed flask, incubated in water batch shaker at 39°C for 72 h and catalyzed by immobilised lipase (Lipozyme TL IM). The products were then separated by filtration, solvent ext...

Phenyl fatty hydroxamic acids (PFHAs) were synthesized in a biphasic organic/aqueous medium from canola oil and phenyl hydroxylamine (PHA). The reaction was carried out in a sealed flask, incubated in water batch shaker at 39°C for 72 h and catalyzed by immobilised lipase (Lipozyme TL IM). The products were then separated by filtration, solvent ext...

Selective protection of some industrially and pharmaceutically important chemicals bearing primary and secondary hydroxyl groups were achieved using 3,4-dihydro-2H-pyran (DHP) as the protecting group by the presence of Keggin H3PW12O40 as catalyst. Findings revealed only protection of the primary alcoholic group in good yields. Different reaction p...

We have investigated the effect of magnetic water treatment on growth and quality improvement of poultry. Some of poultry characteristics have been studied for about 100 chicken samples, including the nonmagnetic samples (drinking by ordinary water) and magnetic samples (drinking by magnetic water). Based on the results of our experiments, magnetic...