Basile Jacquel

Basile Jacquel
Institut de Génétique et de Biologie Moléculaire et Cellulaire | IGBMC · Department of Biology and Stem Cell Development

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6
Publications
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Publications

Publications (6)
Article
Nuclear pore complexes (NPCs) mediate communication between the nucleus and the cytoplasm, and regulate gene expression by interacting with transcription and mRNA export factors. Lysine acetyltransferases (KATs) promote transcription through acetylation of chromatin-associated proteins. We find that Esa1, the KAT subunit of the yeast NuA4 complex,...
Article
Full-text available
The life cycle of microorganisms is associated with dynamic metabolic transitions and complex cellular responses. In yeast, how metabolic signals control the progressive choreography of structural reorganizations observed in quiescent cells during a natural life cycle remains unclear. We have developed an integrated microfluidic device to address t...
Preprint
Full-text available
Nuclear pore complexes (NPCs) mediate communication between the nucleus and the cytoplasm and regulate gene expression by interacting with transcription and mRNA export factors. We find that Esa1, the catalytic subunit of the yeast lysine acetyl-transferase NuA4 complex, acetylates the nuclear basket component Nup60 to promote mRNA export. Acetylat...
Preprint
Full-text available
In response to environmental stress, cellular defense strategies may be divided into two categories: those, as in homeostatic systems, that seek to maintain cell proliferation by degrading the stressor (i.e., resistance); and those that ensure cell survival (i.e. tolerance), even if this is often at the expense of cell proliferation. In this study,...
Preprint
Full-text available
The life cycle of microorganisms is associated with dynamic metabolic transitions and complex cellular responses. In yeast, how metabolic signals control the progressive establishment of structural reorganizations observed in quiescent cells remains unclear. To address this question, we have developed a method that combines nutrient-limited prolife...

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