Basil Nnaemeka ObodoPurdue University West Lafayette | Purdue · Department of Biological Sciences
Basil Nnaemeka Obodo
Master of Science
I am currently investigating the neuro-pathophysiological mechanisms underlying rare genetic disorders.
About
46
Publications
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Introduction
I aim to advance scientific research by providing high-quality professional services in challenging, merit-driven, and result-oriented work environments. My research interests encompass neurogenerative and infectious diseases, with a focus on cell and molecular biology, neurogenetics, clinical chemistry, medical microbiology, and toxicology. Currently, I am working on elucidating the neuro-pathophysiological mechanisms underlying rare genetic disorders.
Additional affiliations
September 2021 - present
Education
September 2021 - January 2023
September 2007 - October 2014
Publications
Publications (46)
Malaria is a mosquito-borne infectious disease of humans and other animals caused by parasitic protozoans (a type of unicellular microorganism) of the genus Plasmodium. This study was designed to assess the nutritional status (serum total protein, albumin, globulin, triglyceride (TG) and total cholesterol) and anthropometric parameters (Body Mass I...
With the increased utilization of assisted reproductive technology (ART), concerns about the potential health risks for ART-conceived babies have also been raised. Increased prevalences of allergic and metabolic diseases have been reported among ART offspring. This study aimed to evaluate the impact of IVF on the tendency to develop allergic respon...
The this study, Cola nitida was used as a test substance to see how it affected sweat electrolytes under different conditions. Participants in the study were sixty (60) non-obese volunteers (30 males and 30 females), aged 18-28, from the University of Benin, and non-habitual chewers of Cola nuts. There were three (3) subgroups: underweight (n=10),...
This study was designed to assess renal function in geriatrics. A total number of 100 subjects were recruited for this study which consists of 70 geriatrics and 30 young adults serving as the control. Venous blood tests were taken from every one of the subjects including the control to assess the degrees of bicarbonate, chloride, potassium, sodium,...
Malaria is a mosquito-borne infectious disease of humans and other animals caused by parasitic protozoans of the genus Plasmodium. Trace elements are dietary mineral that are in very minute quantities and they play significant roles in some biochemical processes leading to modifications of the causes of many diseases and also influence susceptibili...
Assisted reproductive technologies (ART) significantly increase the chance of successful pregnancy and live birth in infertile couples. The different procedures for ART, including in vitro fertilization (IVF), intracytoplasmic sperm injection (ICSI), intrauterine insemination (IUI), and gamete intrafallopian tube transfer (GIFT), are widely used to...
An abattoir, also known as a slaughterhouse, is a place where animals are butchered. The main aim of the study is to isolate and identify Vibrio species on abattoir soils. Soil samples (20 g) were collected from the abattoir in the contaminated areas of Ekpoma and Auchi. The soil samples were collected into a sterile, dark polythene bag using a ste...
An abattoir, also known as a slaughterhouse, is a place where animals are butchered. The main aim of the study is to isolate and identify Vibrio species on abattoir soils. Soil samples (20 g) were collected from the abattoir in the contaminated areas of Ekpoma and Auchi. The soil samples were collected into a sterile, dark polythene bag using a ste...
The aim of this study is to determine the activities of some selected liver enzymes amongst apparently healthy subjects of different blood groups. The study involved 95 apparently healthy students of Ambrose Alli University, Ekpoma, Edo State, Nigeria, between the ages of 18-30, and distributed as follows; blood group O (30), group AB (18), group A...
This study investigates the effect of Xylopia aethiopica leaves on the histology of the kidney. 24 growing rats were used. They were divided into four groups: A (n = 6) as control and B (n = 6), C (n = 6) and D (n = 6) as tests. Group A received normal feed and distilled water only, while B, C and D, received daily doses of 1.2g, 3.0g, and 6.0g / k...
This study was designed to assess the renal function status of the elderly. A total number of One Hundred (100) Subjects were recruited for this study which consists of 50 elderly subjects between 65-100 years old and 50 young adults between 18-30 years who served as the control. Five (5) millilitres of venous blood samples were taken from all the...
Pregnancy is the time during which one or more offspring develops and is characterized by significant changes in metabolism, fluid balance, organ function and blood circulation. This study was set to evaluate the Lipid Profile of Human Immuno Deficiency Virus and Tuberculosis-positive pregnant Women. A total of four hundred (400) subjects were recr...
This study determined urinary tract infection (UTI) among male and female students in AAU. One hundred apparently healthy students comprising 50 males and 50 females within the age range of 18-30 years were enrolled for this study. The samples used were early morning mid-stream urine. The samples were subjected to microscopic examination and also c...
Plasmids, that is, extrachromosomal DNA, were first recognized in Enterobacteriaceae. From that point onward, they were found in practically every one of the strains noticed. The plasmid structure is made out of roundabout twofold abandoned DNA atoms that self-governingly recreate in the host cell. Its length can differ from a couple to many kiloba...
The assessment of bacteria associated with the palms of fresh fish sellers in the Ekpoma market was carried out using standard microbiological techniques. Thirty-six sterile swab sticks were used to collect samples from the hands, knives, and tables of fresh fish sellers in Ekpoma market. Four different bacterial species were isolated and identifie...
Malaria is a mosquito-borne infectious disease of humans and other animals caused by parasitic protozoans (a type of unicellular microorganism) of the genus Plasmodium. Commonly, the disease is transmitted via a bite from an infected female Anopheles mosquito, which introduces the organisms from its saliva into a person’s circulatory system. In the...
In Nigeria, tobacco snuff is the powdered form of smokeless tobacco blended with potash as its main additive. It has been discovered to have several adverse health effects, though perceived by many as safe. In this eight-week study, the effect of tobacco snuff consumption on body weight, physical observation and growth performance of Wistar rats we...
COVID-19 is an infectious respiratory disease that is caused by the SARS-CoV-2 virus. The outcome of this pandemic stemmed the interest for the development and validation of rapid diagnostic tests. This study assessed the diagnostic performance of real time (RT)-PCR and rapid diagnostic test (RDT) kit for the detection of SARS-Cov2 in Respiratory S...
Citrus fruits are rich in bioactive compounds such as vitamin C, carotenoids, flavonoids, vitamin B complex and minerals which are highly beneficial to human’s health. This study was carried out to evaluate the invitro antibacterial and phytochemical activities of ripe and unripe orange peels extract on selected microorganisms. These microorganisms...
COVID-19 is an infectious respiratory disease that is caused by the SARS-CoV-2 virus. The outcome of this pandemic stemmed the interest for the development and validation of rapid diagnostic tests. This study assessed the diagnostic performance of real time (RT)-PCR and rapid diagnostic test (RDT) kit for the detection of SARS-Cov2 in Respiratory S...
Smoking of Cannabis sativa (Marijuana), a known psychoactive substance may result in side effect on living cells of the system. The aim of this study is to assess the complete blood count of Cannabis sativa smokers and make comparison with non-smokers in Ekpoma, Edo State. A total of one hundred subjects were recruited for this study which consist...
Abstract
Dietary intake has been implicated as one of the factors associated with prostate cancer. This study is aimed at assessing the role of high fat diet as a risk factor for prostate cancer. Articles were reviewed which included case control studies, cohort studies or randomized clinical controlled trials published between 1997 and 2017 that f...
ARTICLE INFO ABSTRACT B ackground: Liqu efied petroleu m gas (LPG) has been used extensiv ely for heating , cooking and as a fuel in vehi cles and generators. This study was design ed to evaluate renal and liver pro fil e of LPG pl ant workers in Benin City, Edo State. Methods: A tot al of on e hundred (100) subjects between 20-60 years were recrui...
This study was designed to evaluate the serum levels of creatinine, urea and activities of Alkaline phosphatase (ALP), Gamma glutamyl transferase (GGT), Creatine kinase (CK) and Lactate dehydydrogenase (LDH) among cigarette smokers in Ekpoma, Edo State. This study employed a total of 80 subjects consisting of 50 cigarette smokers and 30 non cigaret...
Liquefied Petroleum Gas (LPG) plant workers are exposed to a number of hydrocarbons from handling petroleum and petroleum-based products and this exposure poses a major health challenge to these workers. This study was designed to evaluate the effects of duration of exposure on biochemical and haematological profile in LPG plant workers. A total of...
Liquefied Petroleum Gas (LPG) plant workers are exposed to a number of hydrocarbons from handling petroleum and petroleum-based products and this exposure poses a major health challenge to these workers. This study was designed to evaluate the effects of duration of exposure on biochemical and haematological profile in LPG plant workers. A total of...
to determine the relationship between CD4+ count, ART and parasitic infections as this will help be of immense benefit to government and healthcare policies.
to determine the relationship between CD4+ count, ART and parasitic infections as this will help be of immense benefit to government and healthcare policies.
Pregnancy involves various physiologic, metabolic and anatomic changes in the maternal environment. This study was designed to assess the Body Mass Index (BMI), activities of G6PD and uric acid levels in different trimesters of pregnancy. A total of eighty (80) subjects were used for this study which consist of sixty (60) pregnant women, 20 for eac...
Background: Regardless of the type of diabetes mellitus, there is always a Beta-cell dysfunction leading to absolute insulin deficiency in type 1 diabetes mellitus or associated with insulin resistance in case of type 2 diabetes mellitus.
Materials and Methods: A total of 267 subjects consisting of 164 diabetic patients and 103 non-diabetic appare...
Malnutrition remains a significant but intriguing consequence of HIV and TB infections. This study was set to evaluate the Nutritional Indices of Human Immuno Deficiency Virus and Tuberculosis positive pregnant Women. A total of four hundred (400) subjects were recruited for this study which comprised of 150 HIV positive pregnant women, 150 TB posi...
Tuberculosis and Human Immunodeficiency Virus (HIV) infections are diseases which affect the immune system of the body. The aim of this study is to evaluate the activities of AST, ALT and ALP in Tuberculosis and HIV subjects. A total of one hundred and fifty subjects were recruited for this study which comprised of fifty (50) HIV infected subjects,...
This study was undertaken to assess the thyroid profile of diabetes mellitus (DM) patients and patients with some associated complications in the Edo state, Nigeria. Blood samples from 267 subjects, consisting of 164 diabetic patients (24 type 1 DM and 140 type 2 DM) and 103 nondiabetic apparently healthy individuals (as controls), were analyzed. T...
Palm wine is a popular traditional alcoholic beverage consumed by more than 10 million people in West Africa. It is a sweet, effervescent drink obtained from the sap of the oil palm, Elaeis guineense and raphia palm, Raphia hookeri. The aim of this study is to evaluate the microbial load of palm wine sold in Ekpoma, Edo State. Identification of yea...
This study was carried out to assess the nutritional indices of children infected with malaria at Irrua Specialist Teaching Hospital Irrua, Edo State. A total of 200 children comprising one hundred and twenty (120) children infected with malaria and a control group consisting of eighty (80) apparently healthy children was used for this study. The r...
A total of 200 swabs from clinical samples and fomites which comprised of 105 swabs from the skin, 56 swabs from nasal and 38 swabs from fomites i.e laboratory coats, each were collected and examined. From this study, 30(15.0%) were identified as Staphylococcus aureus, and 170(85.5%) showed no growth or other species of bacteria and analysis show t...
This study determined the prevalence of malaria infection among 146 pregnant women attending antenatal clinics in Ekpoma and its environs, in relation to blood groups and haemoglobin genotypes. They comprised 62, 40 and 44 pregnant women in their first, second and third trimesters respectively. Venous blood for the determination of haemoglobin geno...
This study is designed to evaluate human serum levels of creatinine, urea and uric acid in the different trimesters of pregnancy. A total number of 120 subjects were recruited from primary health care centres in Ekpoma [30 pregnant women for each of the trimesters (3x30=90) and 30 non-pregnant women serving as the control]. Venous blood samples wer...
Human serum protein and C-reactive protein levels were determined among HIV patients visiting St Camillus Hospital, Uromi, Edo State, Nigeria, between January to March 2013. Fifty (50) HIV patients (20 males; 30 females) and 50 control subjects (24 males; 26 females) were enrolled on this study. The clinical status of the patients was obtained from...
This study is intended to investigate the effect of Potash on renal function. Twenty four (24)
Albino wistar rats with mean weight of 126.3±23.9g were used. They were subdivided into four
groups -A, B, C and D (n=6 each); with A serving as control while B, C and D served as test
groups. Group A received normal feed and water while B, C and D rec...
This study investigates the possible toxic effect of Xylopia aethiopica on liver function via the evaluation of some serum biochemical parameters. The study involved 24 adult rats with weight ranging from 150 to 300g and divided into four groups of 6 rats each (A, B, C and D). For 21 days, varying doses of 1.2g/kg, 3.0g/kg and 6.0g/kg per body weig...
The effect of Xylopia aethiopica leaves on body weight and growth performance was studied on growing Wistar rats. The study involved twenty-four rats of comparable sizes and weights ranging from 150 to 300g and divided into four groups of six rats each. Group A served as the control while groups B, C and D served as the test and received 1.2g, 3.0g...
The effect of Xylopia aethiopica leaves on body weight and growth performance was studied on growing Wistar rats. The study involved twenty-four rats of comparable sizes and weights ranging from 150 to 300g and divided into four groups of six rats each. Group A served as the control while groups B, C and D served as the test and received 1.2g, 3.0g...
This study investigates the possible toxic effect of Xylopia aethiopica on liver function via the evaluation of some serum biochemical parameters. The study involved 24 adult rats with weights ranging from 150 to 300g and divided into four groups of 6 rats each (A, B, C and D). For 21 days, varying doses of 1.2g/kg, 3.0g/kg and 6.0g/kg per body wei...
This study aimed at investigating the relationship between some selected socio-demographic profiles and malaria parasitic infections in cord blood. It involved 100 cord blood samples of newly delivered babies at the Irrua Specialist Teaching Hospital, Irrua, Edo State. Samples were subjected to microscopic examinations following standard protocols...