
Barbara YawnUniversity of Minnesota | UMN · Department of Family Medicine and Community Health
Barbara Yawn
MD MSc MSPH FAAFP
About
684
Publications
120,117
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Introduction
Pragmatic clinical trails and large health database research in asthma and COPD and in Herpes zoster and PP depression Currently I am consulting on other reseearchers' RO1s and large PCORI grants and working with pharma groups on non-drug trials.
Education
September 1988 - June 1990
September 1975 - December 1978
July 1973 - June 1976
Publications
Publications (684)
Rationale: The impact of COPD screening on US primary care clinician behavior and patient outcomes is unclear. Objectives: Assess the impact of receiving CAPTURE (COPD Assessment in Primary Care to Identify Undiagnosed Respiratory Disease and Exacerbation Risk) screening scores on clinical and patient outcomes. Methods: Cluster randomized trial inc...
Background
Preserved ratio impaired spirometry (PRISm) represents a population with spirometry results that do not meet standardized COPD obstruction criteria, yet present with high respiratory symptom burden and might benefit from respiratory management and treatment. We aimed to determine prevalence of PRISm in US primary care patients diagnosed...
Primary care clinicians play a key role in asthma and asthma exacerbation management worldwide because most patients with asthma are treated in primary care settings. The high burden of asthma exacerbations persists and important practice gaps remain, despite continual advances in asthma care. Lack of primary care-specific guidance, uncontrolled as...
Objective
People with advanced chronic obstructive pulmonary disease (COPD) have substantial palliative care needs, but uncertainty exists around appropriate identification of patients for palliative care referral.
We conducted a Delphi study of international experts to identify consensus referral criteria for specialist outpatient palliative care...
Background
Herpes zoster (HZ), commonly known as “shingles,” may contribute to cognitive decline through mechanisms such as neuroinflammation or direct neuronal injury. However, evidence on the longitudinal association between HZ and cognitive decline is conflicting and whether the risk differs by APOE ε4-carrier status has not been studied; prospe...
Background:
Black and Latinx adults experience disproportionate asthma-related morbidity and limited specialty care access. The SARS-CoV-2 pandemic expanded telehealth use.
Objective:
To evaluate visit type (telehealth [TH] vs. in-person [IP]) preferences and the impact of visit type on asthma outcomes among Black and Latinx adults with moderate...
New updates in the Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2023 report include major changes to initial disease assessment and pharmacologic therapy, highlighting the clinical relevance of exacerbations. The updated GOLD 2023 algorithms offer a shorter path to consideration of triple therapy, including both initial and follow-...
Background
Patients with mild asthma are believed to represent the majority of patients with asthma. Disease-associated risks such as exacerbations, lung function decline, and death have been understudied in this patient population. There have been no prior efforts from major societies to describe research needs in mild asthma.
Methods
A multidisc...
Importance:
Chronic obstructive pulmonary disease (COPD) is underdiagnosed in primary care.
Objective:
To evaluate the operating characteristics of the CAPTURE (COPD Assessment in Primary Care To Identify Undiagnosed Respiratory Disease and Exacerbation Risk) screening tool for identifying US primary care patients with undiagnosed, clinically si...
In 2020, chronic obstructive pulmonary disease (COPD) was the fifth leading cause of death in the United States excluding COVID-19, and its mortality burden has been rising since the 1980s. Smoking cessation, long-term oxygen therapy, noninvasive ventilation, and lung volume reduction surgery have had a beneficial effect on mortality; however, unti...
Plain Language Summary
What is the context?After experiencing chickenpox, the varicella-zoster virus remains in the body and can be reactivated years later in a form called herpes zoster, more commonly known as shingles.
Although shingles is more common in people aged ≥ 50 years, it is also more likely to occur in people with immune systems that do...
In order to maximise the learning potential of medical education programmes aimed at interdisciplinary or multidisciplinary teams, it is important to understand how the effectiveness of these programmes can vary between healthcare professionals from different specialities. Measuring the impact of educational activities between specialities may faci...
Introduction
The objective of this analysis was to compare the Asthma Control Test (ACT) and the Asthma APGAR asthma control assessment tools in African-Ancestry/Black (AA/B) and Hispanic/Latinx (H/L) adults with moderate to severe asthma.
Methods
This pre-planned sub-study of the PREPARE clinical trial compares the baseline ACT and Asthma APGAR s...
Objectives
We aimed to summarize the known risk of vasculopathy (stroke, myocardial infarction [MI], and transient ischemic attack [TIA]) after herpes zoster (HZ) and the impact of antiviral treatment and vaccination against HZ on the risk of vasculopathy.
Materials and methods
A narrative literature review was conducted in PubMed to identify evid...
Chronic obstructive pulmonary disease (COPD) has been reported as a potential risk factor for developing herpes zoster (HZ). We aimed at comparing incidence rates of HZ between people with versus without COPD in the US. This retrospective cohort study used data from Optum's de‐identified Clinformatics Data Mart database from 1/1/2013 through 12/31/...
Introduction
The Asthma Impairment and Risk Questionnaire (AIRQ®) is a 10 item, yes/no, impairment- and risk-based control assessment. Scores of 0-1 indicate well-controlled (WC), 2-4 not-well controlled (NWC), and 5-10 very poorly controlled (VPC) asthma. The Asthma Checklist is a decision support tool designed to facilitate implementation of Guid...
Objectives:
To assess healthcare professionals' (HCPs) knowledge of increased HZ risk and burden for patients with chronic obstructive pulmonary disease (COPD), HCPs' familiarity with Advisory Committee on Immunization Practice's (ACIP) HZ vaccine recommendations and the HCPs' current adult vaccine practices. To evaluate the impact of a short educ...
Although spirometry is a simple, portable test and recommended for the diagnosis of asthma and chronic obstructive pulmonary disease (COPD), it is not routinely used in the primary care setting. Minorities and underserved populations are less likely to have spirometry assessment, leading to both over and misdiagnosis of asthma and COPD. Because dys...
Purpose:
To describe demographic and clinical characteristics of chronic obstructive pulmonary disease patients managed in US primary care.
Methods:
This was an observational registry study using data from the Chronic Obstructive Pulmonary Disease (COPD) Optimum Patient Care DARTNet Research Database from which the Advancing the Patient Experien...
Background
We investigated the longitudinal association of herpes zoster (HZ), commonly known as “shingles,” and long‐term risk of stroke or coronary heart disease (CHD) among participants in 3 large US cohorts, the NHS (Nurses' Health Study), NHS II (Nurses' Health Study II), and HPFS (Health Professionals Follow‐Up Study).
Methods and Results
Pa...
Introduction:
Little is known about the variability in chronic obstructive pulmonary disease (COPD) management and how it may be affected by patient characteristics across different healthcare systems in the US. This study aims to describe demographic and clinical characteristics of people with COPD and compare management across five primary care...
Herpes zoster (HZ) is common in older adults with conditions such as chronic obstructive pulmonary disease (COPD). Effective prevention is available through vaccination, but HZ vaccine uptake remains incomplete. Using an online survey of people with self-reported COPD, ShiPPS assessed HZ risk awareness, HZ vaccine use and barriers, and the impact o...
MeiLan Han,1 Barry Make,2 Barbara P Yawn3 1Department of Internal Medicine, University of Michigan Health System, Ann Arbor, MI, USA; 2Pulmonary Sciences and Critical Care Medicine, National Jewish Health, Denver, CO, USA; 3Department of Family and Community Health, University of Minnesota, Minneapolis, MN, USACorrespondence: Barbara P Yawn, Depart...
Background:
Black and Latinx patients bear a disproportionate burden of asthma. Efforts to reduce the disproportionate morbidity have been mostly unsuccessful, and guideline recommendations have not been based on studies in these populations.
Methods:
In this pragmatic, open-label trial, we randomly assigned Black and Latinx adults with moderate...
Introduction:
Many studies have been conducted worldwide to estimate herpes zoster (HZ) incidence rates. We synthesized studies of HZ incidence rates in the general population using meta-analysis models.
Methods:
A random effects meta-analysis was conducted to estimate HZ incidence from a published worldwide systematic literature review (SLR) in...
Background
Many studies have been conducted worldwide to estimate Herpes Zoster (HZ) incidence rates and temporal trends. We systematically reviewed and synthesized studies of HZ incidence rates in the general population using meta-analysis models.
Methods
A random-effects meta-analysis was conducted to estimate HZ incidence from a published world...
Background
To document a generalizable process for developing a patient-prioritized chronic obstructive pulmonary disease (COPD) research agenda and to provide an overview of domains that were developed in response to people living with COPD and caregivers’ suggestions for research.
Methods
Adults with COPD and caregivers who are members of the CO...
Background
Clinician’s asthma guideline adherence in asthma care is suboptimal. The effort for improving adherence can be enhanced by assessing and monitoring clinician’s adherence to guidelines reflected in electronic health records (EHRs) which yet requires costly manual chart review since many care elements cannot be identified by structured dat...
Background:
Patients with chronic obstructive pulmonary disease (COPD) are potentially at increased risk of herpes zoster (HZ). Little is known about the impact of an HZ episode on health care resource utilization (HRU) and costs among patients with COPD.
Methods:
This retrospective cohort study of individuals aged ≥50 years in the United States...
Background:
Electronic medication monitors (EMMs) are associated with decreased rescue inhaler use, symptom burden, and increased medication adherence in asthma. However, the use of EMMs in people with chronic obstructive pulmonary disease (COPD) using the ELLIPTA dry powder inhaler has not been studied.
Methods:
An open-label, single-arm, prosp...
Purpose:
Pharmacotherapy is one cornerstone of Chronic Obstructive Pulmonary Disease (COPD) management. Published U.S. data seldom includes patient-reported COPD medication use and adherence. We add this patient perspective to the commonly reported administrative prescribing and fill data.
Methods:
This survey study used inhaler and nebulizer pi...
Barbara P Yawn,1 Barry Make,2 David Mannino,3 Fernando J Martinez,4 Meilan K Han5 1Department of Family and Community Health, University of Minnesota, Minneapolis, MN, USA; 2Pulmonary Sciences and Critical Care Medicine, National Jewish Health, Denver, CO, USA; 3College of Public Health, Department of Preventive Medicine and Environmental Health, U...
Learning objectives:
• Collaborate with patients to inform treatment decision-making that addresses their symptoms, goals, and concerns • Individualize guideline-recommended therapy to reduce chronic obstructive pulmonary disease (COPD) exacerbations, improve lung function, manage daily symptoms such as breathlessness, and help achieve the patient...
Pulmonary rehabilitation is a highly effective treatment for people with chronic lung disease but remains underused across the world. Recent years have seen the emergence of new program models that aim to improve access and uptake, including telerehabilitation and low-cost, home-based models. This workshop was convened to achieve consensus on the e...
We conducted a systematic review to characterize the incidence rate of herpes zoster (HZ) in the general population, specifically in individuals ≥50 years of age. A total of 69 publications were included in the review. We found a cumulative incidence of HZ ranging from 2.9-19.5 cases per 1,000 population and an incidence rate of HZ ranging from 5.2...
Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality. Early detection and appropriate treatment and management of COPD can lower morbidity and perhaps mortality. Clinicians in the primary care setting provide the majority of COPD care and are pivotal in the diagnosis and management of COPD. In this review, we p...
A workshop "Electronic Health Records and Pulmonary Function Data: Developing an Interoperability Roadmap" was held at the American Thoracic Society 2019 International Conference. "Interoperability" is defined as is the ability of different information-technology systems and software applications to directly communicate, exchange data, and use the...
The Advancing the Patient Experience (APEX) in Chronic Obstructive Pulmonary Disease (COPD) registry (https://www.apexcopd.org/) is the first primary care health system-based COPD registry in the United States. While its ultimate goal is to improve the care of patients diagnosed with COPD, the registry is also designed to describe real-life experie...
Background
Previous studies have evaluated the risk of developing herpes zoster (HZ) in patients with chronic obstructive pulmonary disease (COPD), but little is known about the impact of an acute HZ episode on healthcare resource utilization (HCRU) and costs among patients with COPD in the US.
Methods
A retrospective cohort study of individuals ≥...
Background
Asthma prevalence, morbidity, and mortality disproportionately impact African American/Black (AA/B) and Hispanic/Latinx (H/L) communities. Adherence to daily inhaled corticosteroid (ICS), recommended by asthma guidelines in all but the mildest cases of asthma, is generally poor. As-needed ICS has shown promise as a patient-empowering ast...
Background:
Chronic obstructive pulmonary disease (COPD) is commonly managed by family physicians, but little is known about specifics of management and how this may be improved. The Advancing the Patient Experience in COPD (APEX COPD) registry will be the first U.S. primary care, health system-based registry following patients diagnosed with COPD...
After participating in this activity on chronic obstructive pulmonary disease (COPD), family physicians will be better able to: Identify symptomatic patients at increased risk of COPD to prompt early diagnostic evaluation. Individualize evidence-based therapy with the goal of reducing COPD exacerbations and improving patient outcomes. Identify the...
Introduction
CPAP therapy is prescribed to help manage disordered breathing during sleep time periods. Most users, especially those with non-severe obstructive sleep apnea (OSA), use it only for some portion of their sleep period. Patients with Overlap Syndrome have both OSA and chronic obstructive pulmonary disease (COPD). While there has been som...