Bárbara Padilla-Fernández

• University of La Laguna

Introduction: Evaluation of long term results, risk factors for treatment failure and complications in a contemporary cohort of patients with bulbar urethral strictures managed with direct vision internal urethrotomy (DVUI). Methods: We retrospectively reviewed 140 consecutive patients who underwent internal urethrotomy in a single institution b...

Background/Objectives: Female stress urinary incontinence (SUI) surgical treatment has changed since its beginning. Selecting materials that promote constructive tissue remodelling helps to maintain continence after surgery and minimizes complications. To analyze the long-term urinary continence results in women who underwent SUI surgical correctio...

Introduction: The protocol for deceased donor kidney transplants has been standardised. The procedure for a living donor has peculiarities derived from the differences in the graft. When a living kidney donor program is implemented, changes occur in both the profile of the kidney transplant candidate and in the postoperative treatments. Aims: To di...

Introduction: Mental disorders, smoking, or alcoholism and benign prostate disease are highly prevalent in men. Aims: To identify the relationship between mental disorders, smoking, or alcoholism and benign prostate disease. Methodology: A prospective multicenter study that evaluated prostate health status in 558 men from the community. Groups: GP—...

Aims The postvoid residual (PVR) volume of urine in the bladder is widely used in clinical practice as a guide to initiate treatment, including clean‐intermittent self‐catheterization (CISC). It is often believed that an elevated PVR causes complications such as recurrent urinary tract infections (UTI) and renal failure. However, evidence for this...

Introduction/Objectives This study aims to describe the procedure and effectiveness of the four-vertex technique for correcting urethral prolapse in women. Methods and Materials includes a retrospective case series of 17 patients who underwent surgery for urethral prolapse. Two study groups were distinguished based on the presence or absence of pe...

Balloon dilatation of the external urethral sphincter was developed as a less-invasive alternative to sphincterotomy in patients with detrusor-sphincter dyssynergia, with no negative effect on sexual function and a low complication rate. However, its high recurrence rate has prevented the general approval of the technique. Surgical procedures invol...

Introduction: Post-prostatectomy urinary incontinence (PPUI) has an enormous impact in quality of life (QoL). Transobturator-rethrourethral sling (AdVanceTMXP sling) is a well-established treatment option although there is paucity of data on long-term outcomes. Our objective was to assess the long-term functional outcomes and QoL in a cohort of me...

Purpose of Review No specific guidelines have been developed for acute cystitis management during the COVID-19 pandemic. This review aims to provide up-to-date information about treatment and follow-up in patients with symptoms suggesting lower urinary tract infection. Recent Findings Uncomplicated cystitis does not need microbiological confirmati...

Neuromodulation is recommended by major international guidelines as a fourth-line treatment in bladder pain syndrome/interstitial cystitis (BPS/IC) patients after failure of behavioural, oral and intravesical pharmacological treatments, including hydrodistension. A non-systematic review of studies identified by electronic search of MEDLINE was perf...

Introduction and objectives: The Acute Cystitis Symptom Score (ACSS) is a patient self-reporting questionnaire for clinical diagnostics and patient-reported outcome (PRO), which may assess the symptoms and the effect on the quality of life in women with acute cystitis (AC). The current study aimed to create a validated Spanish version of the ACSS...

Introduction The COVID-19 pandemic has dramatically affected the Female and Functional Urology (FFU) practice, leading to massive waiting lists, while patients’ quality of life remains severely impaired. The aim of the present study is to develop consensual recommendations to guide clinicians on the management of FFU patients. The present paper foc...

Background: In this report, we describe a modification of transcorporal artificial urinary sphincter place ment known as Gullwing modification. Description of technique: Using a penoscrotal approach, bilateral corpora cavernosa flaps are harvested and sutured in the midline covering the lateral and ventral surfaces of the urethra. Transcorporal...

Introduction and objective Cancer-specific anxiety is the most frequently reported psychological response after radical prostatectomy (RP). We evaluated the prevalence of pretreatment psychiatric pathology in patients with prostate cancer undergoing RP and identified the effects of psychiatric diagnoses on their survival and prognosis. Material an...

Background: Prostate cancer is currently the most common malignant tumour in men. Research on hormone therapy advances is necessary because, unfortunately, some tumours are not organ-confined. Objective: To review and analyse the current state of evidence regarding clinical trials with neoadjuvant or adjuvant hormone therapy for prostate cancer and...

Resumen Introducción y objetivo La ansiedad específica del cáncer (CSA) es la reacción psicológica más frecuente tras la prostatectomía radical (PR). Evaluamos la prevalencia de la patología psiquiátrica pretratamiento de cáncer de próstata mediante PR e identificamos la influencia de los diagnósticos psiquiátricos en la supervivencia y pronóstico...

Introduction The 3-Day Bladder Diary (3dBD) has good feasibility, reliability and validity for the assessment of Lower Urinary Tract Symptoms (LUTS) in women. This study aims to evaluate the reliability of the first day of the 3dBD (fdBD) in the assessment of the symptoms of women with LUTS. Materials and Methods An epidemiologic, descriptive and...

Purpose of review Our goal was to summarize recent evidence regarding recurrent urinary tract infections and asymptomatic bacteriuria in different adult populations. Recent findings Several research groups are focused on the description of resident bacterial flora in the bladder and urinary dysbiosis in the microbiome era. Even the definitions mig...

Lower urinary tract infections (UTI) usually do not affect renal function [1], but it has been described a subclinical or silent damage of the renal parenchyma in 30% of the cases [2, 3], especially if the patient has had a UTI in the previous month or in lower UTI lasting more than 7 days [4]. Renal function alteration may carry important conseque...

Prostate cancer is the second most commonly diagnosed cancer in men, with an estimated 1,276,106 diagnoses worldwide in 2018, accounting for 7.1% of all cancers diagnosed (including both sexes) [1]. Family history and racial/ethnic background are associated with an increased incidence suggesting a genetic predisposition, but less than 10% of men wi...

Vesicovaginal fistulas (VVaFs) are relatively uncommon in developed countries but with devastating consequences for the women suffering them. Conservative management has a low response rate. The surgical repair is a technically demanding procedure. Transvaginal, open transabdominal or laparoscopic (pure or robot-assisted) approaches have been descr...

Urinary tract infections affect more than 50% of women. 25% derive from recurrent UTI (RUTI). It is not known the relationship between obstetric history and RUTI occurrence. Investigate the relationship between obstetric events and RUTI. Multicenter observational retrospective study. Groups: G.RUTI (n = 294): women with RUTI; G.NON.RUTI (n = 126):...

Context Controversy still exists regarding the balance of benefits and harms for the different surgical options for neurogenic stress urinary incontinence (N-SUI). Objective To identify which surgical option for N-SUI offers the highest cure rate and best safety without compromising urinary tract function and bladder management. Evidence acquisit...

Purpose: This study aimed to determine the effectiveness of whole-cell bacterial immunotherapy, i.e. MV140 and autovaccines, in reducing the number ofurinary tract infections (UTIs)in frail elderly patients with recurrent UTI (RUTI). Method: A prospective cohort observational study was performed including 200 frail elderly subjects suffering RUT...

Aim To perform a cross-cultural adaptation and validation of the Neurogenic Bladder Symptom Score (NBSS) to Spanish in patients with neurogenic lower urinary tract dysfunction. Materials and Methods The questionnaire was culturally adapted according to international guidelines. It was applied, twice in a range of 14–28 days. Psychometric propertie...

Context Neurourological patients often encounter bacteriuria without any symptoms or may experience symptoms suspicious of urinary tract infections (UTIs). However, there is a lack of guidelines that unequivocally state the definition of UTIs in this specific patient group. Objective To present all used definitions of UTIs in neurourological patie...

Background: When conservative management fails, patients with stress urinary incontinence (SUI) are considered for surgical treatment. Simpler, more economical and less invasive surgical techniques, such as the Remeex® system, have been developed. Objectives: To analyze the objective effectiveness of the Remeex® system in the treatment of male s...

Urethral stricture is a rare condition in women, representing a diagnostic challenge for the urologist. Its main etiology is traumatic or due to labor. Definitive treatment can be by means of dilations or urethroplasty using both local flaps and free grafts. In this study, we report the case of a patient with voiding symptoms during a period of 9 y...

Objective: To prove the benefits of pelvic floor muscle training with biofeedback (BFB) as a complementary treatment in women with bladder pain syndrome/interstitial cystitis (BPS/IC). Methods: Prospective, randomized study in 123 women with BPS/IC. Groups: BFB+ (n = 48): women with oral drug treatment (perphenazine and amitriptyline) plus intra...

Objective To characterize the impact on kidney injury of recurrent urinary tract infections (RUTI) in the frail elderly. Methods Prospective observational study in 200 frail elderly subjects for 1 year. Groups: GA ( n = 100): subjects without RUTI, GB ( n = 100): subjects with RUTI. Variables: age, concomitant diseases, glomerular filtration rate...

Introduction Prostate cancer (PCa) is the second most common male cancer in the world. Its incidence is estimated to grow to 1.7 million new cases and 499,000 new deaths by 2030. Treatment of OCPC can affect patients physically and mentally, as well as their close relationships and their job or career, which conditions health-related quality of lif...

Introduction: Prostate-specific antigen velocity (PSAV) is used to monitor men with clinical suspicion of prostate cancer (PCa), with a normal cut-off point of 0.3-0.5 ng/mL/year. The aim of the study is to establish the predictive capacity of PSAV (value and acceleration) and of the free PSA/total PSA index or ratio. Method: Prospective multice...

Objectives: to demonstrate the benefits of physiotherapy (PT) with pelvic floor biofeedback (BFB) in improving health-related quality of life when used as a complementary therapy after surgical treatment of cystocele, in cases in which perineal pain or discomfort persists. Materials and methods: prospective observational study in 226 women who r...

Introduction: High performance female athletes may be a risk group for the development of urinary incontinence due to the imbalance of forces between the abdomen and the pelvis. Pelvic floor physiotherapy may be a useful treatment in these patients. Objectives: (1) To identify the scientific evidence for pelvic floor (PF) dysfunctions that are asso...

Summary.- OBJECTIVES: To report the recommendations of an expert panel to reorganize Neurourology units and to prioritize examinations and both conservative and surgical treatments during the COVID-19 pandemic. MATERIALS AND METHODS: Non-systematic review of the literature and national experts’ opinion summarizing the recommendations in the diagnos...

Introduction: Prostate cancer (PCa) is the second most common male cancer in the world. Its incidence is estimated to grow to 1.7 million new cases and 499,000 new deaths by 2030. Treatment of OCPC can affect patients physically and mentally, as well as their close relationships and their job or career, which conditions health-related quality of l...

Introduction: Stress urinary incontinence (SUI) has an incidence of 15-80% in women. One of the most widely used surgical techniques for treatment is the placement of a suburethral transobturator tape (TOT). Although this technique has a relatively low morbidity rate, it is not exempt from intraoperative or postoperative complications, which can h...

Introduction The influence of tobacco on the microbiological spectrum, resistance-sensitivity pattern and evolution in patients with recurrent urinary tract infections (RUTI) is analyzed. Evaluation of the effect of polyvalent bacterial vaccine on the prevention of RUTI and smoking status. Material and methods Retrospective multicenter study of 85...

Objectives: To Evaluate the severity of symptoms in OAB patients and their outcomes expectations, symptoms management and Health-Related Quality of Life (HRQoL). Material and methods: Epidemiological, multicentre, non-interventional, cross-sectional study, conducted by 294 physicians in Spain in clinical practice. Female adult patients with OAB...

Purpose of Review In this review, the current literature available about sacral neuromodulation (SNM) in the management of bladder pain syndrome/interstitial cystitis (BPS/IC) will be addressed. Recent Findings SNM has emerged in recent years as a minimally invasive option of management for refractory BPS/IC patients that otherwise should undergo...

Context Coronavirus disease 19 (COVID-19) has changed standard urology practice around the world. The situation is affecting not only uro-oncological patients but also patients with benign and disabling conditions who are suffering delays in medical attention that impact their quality of life. Objective To propose, based on expert advice and curre...

Objectives: To report the recommendations of an expert panel to reorganize Neurourology units and to prioritize examinations and both conservative and surgical treatments during the COVID-19 pandemic. MATERIALS AND METHODS: Non-systematic review of the literature and national experts' opinion summarizing the recommendations in the diagnosis, manag...

Resumen Introducción Se analiza la influencia del tabaco en el espectro microbiológico, patrón de resistencia-sensibilidad y evolución en pacientes con infección de orina de repetición (ITUR). Evaluación del efecto de vacuna bacteriana polivalente en la prevención de las ITUR y el estado como fumador. Material y métodos Estudio retrospectivo mult...

Introduction Prostate cancer is the most common visceral neoplasm in men and the second one in the United States with the highest mortality behind lung cancer and ahead of colorectal cancer. While prostate cancer mortality rates have been reduced in the United States, Austria, United Kingdom and France, 5-year survival rates have been incremented i...

Aims: Pelvic organ prolapse (POP) is a very prevalent condition with a great impact on women's quality of life. At present, there is great controversy regarding the use of mesh in POP surgery. To understand the current moment, it is advisable to make a brief summary of the historical evolution of mesh use for pelvic floor pathology. The aim of thi...

Background and aim Pulmonary thromboembolism is one of the most common causes of non-surgical death in patients following urological abdominopelvic surgery. Since the beginning of prophylaxis for venous thromboembolic disease, episodes of deep vein thrombosis and pulmonary thromboembolism have decreased. Our objective is to analyse the prognosis fa...

Resumen Introducción El cáncer de próstata es la neoplasia visceral más frecuente en el varón, y en Estados Unidos es la segunda con mayor mortalidad, por detrás del cáncer de pulmón y por delante del cáncer colorrectal. La mortalidad por cáncer prostático se ha reducido en Estados Unidos, Austria, Reino Unido y Francia, mientras que la superviven...

Aims: The aim of this paper is to stablish de position of the Ibero-American Society of Neurourology and Urogynecology (SINUG) in relation to the use of suburethral meshes for the surgical treatment of female stress incontinence. Methods: Tension-free mid-urethral slings (MUS) have become the most popular procedure for the treatment of stress ur...

Resumen Antecedentes y objetivo El tromboembolismo pulmonar es una de las causas más comunes de muerte no quirúrgica en pacientes sometidos a cirugía urológica abdominopélvica. Desde el inicio de la profilaxis para la enfermedad tromboembólica venosa los episodios de trombosis venosa profunda y tromboembolia pulmonar han descendido considerablemen...

Introduction The classical teaching methodology was based on passive transmission-based learning. The model has changed toward an orientation based on student-centered learning. Objective The objective of the study has been to evaluate the students’ perception when learning about urinary tract infections, and their perspective about the teaching i...

ABSTRACT The classical teaching methodology was based on the passive transmission of content. The model has changed towards an orientation based on the fact that the axis of the teaching-learning system is the student. The objective of the study is to evaluate the perception of learning related to urinary tract infections that the students have, an...

There is an ongoing debate in functional urology forums about the role and utility of urodynamics as a diagnostic and prognostic tool for patients with urinary incontinence. Current evidence suggests that in a limited number of patients with pure stress urinary incontinence (those without relevant urogynaecological comorbidities and a low postvoid...

INTRODUCTION AND OBJECTIVES: Objective: to report the experience in 4 tertiary hospitals with the pre-connected, pre-filled and refillable artificial urinary sphincter (AUS) ZSI 375 PF (Zephyr Surgical Implants, Geneva, CH). METHODS: Retrospective, nonrandomised, multicentre study. From December 2015 to June 2018, 28 male patients (PTS) underwent...

Balloon dilatation has been proposed as a potential approach for the management of detrusor external sphincter dyssynergia, which is a technically-simple approach with a low chance for blood loss or other associated complications. Fluoroscopy might guide positioning and allows the performance of a retrograde urethrogram to assess for extravasation.

Introduction & Objectives: The artificial urinary sphincter (AUS) is now considered the gold standard for the management of severe stress urinary incontinence (UI) in males with a high success rate. The aim of the study is to report the experience in 4 tertiary hospitals with the pre-connected, pre-filled and refillable AUS ZSI 375 PF (Zephyr Surgi...

Surgical sphincterotomy aims to decrease outlet resistance in order to protect the upper urinary tracts, reduce risk of urinary tract infection, and diminish rates of autonomic dysreflexia in the face of neurogenic DESD [1]. Indications include worsening hydronephrosis, vesicoureteral reflux, autonomic dysreflexia and recurrent UTIs believed to be...

Purpose This work represents the efforts of the SIU-ICUD workgroup on this topic and comprehensive literature search of English language manuscripts regarding urologic surgery in spinal cord injury using key words of urologic surgery and spinal cord injury. Articles were compiled, and recommendations in the chapter are based on group discussion and...

Context: The objective of evidence-based medicine is to employ the best scientific information available to apply to clinical practice. Understanding and interpreting the scientific evidence involves understanding the available levels of evidence, where systematic reviews and metaanalyses of clinical trials are at the top of the levels-of-evidence...

Context: The objective of evidence-based medicine is to employ the best scientific information available to apply to clinical practice. Understanding and interpreting the scientific evidence involves understanding the available levels of evidence, where systematic reviews and meta-analyses of clinical trials are at the top of the levels-of-evidenc...

Aim: The main goals of neurogenic lower urinary tract dysfunction (NLUTD) management are preventing upper urinary tract damage (UUTD), improving continence, and quality of life. Here, we aimed to systematically assess all available evidence on urodynamics predicting UUTD in patients with NLUTD. Methods: A systematic review according to the Prefe...

Chondroma is a benign tumour of mesenchymal origin that is composed of cartilage and rarely located in soft tissues, being described so far only in four cases, as located in the bladder, according to our knowledge. We describe the fifth case of a 67-year-old woman who consulted for microscopic haematuria, with an endoscopic finding of submucosal no...

Aims: To describe all outcome parameters and definitions of cure used to report on outcome of surgical interventions for stress urinary incontinence (SUI) in neuro-urological (NU) patients. Methods: This systematic review was performed and reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) state...

Introduction The objective of this study was to determine the reproducibility in a murine model of renal tumors of various histological strains that could be useful for investigating the response to target drugs. Material and methods Development and analysis of the “in vivo” model: tumor xenograft of renal cell carcinomas with Balb/c nude athymic...

Objective: To study whether there are factors related to secondary diagnoses (SDg) present in patients with prostate cancer that influence the development of urinary incontinence after radical prostatectomy (RP). Materials and methods: A retrospective multicenter observational study was performed reviewing the medical records of 430 men who unde...

Introduction: The objective of this study was to determine the reproducibility in a murine model of renal tumours of various histological strains that could be useful for investigating the response to target drugs. Material and methods: Development and analysis of the "in vivo" model: tumour xenograft of renal cell carcinomas with Balb/c nude at...

Aims: To systematically evaluate effectiveness and safety of bladder augmentation for adult neuro-urological patients. Methods: The Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) statement was followed for review of publications. The Medline, Embase, and Cochrane controlled trial databases and clinicaltrial.gov were s...

Aims: To systematically review all available evidence on the effectiveness and complications of continent cutaneous stoma or tube (CCS/T) to treat bladder-emptying difficulties in adult neuro-urological patients. Methods: The search strategy and studies selection were performed on Medline, Embase, and Cochrane using the PICOS method according to...

The aim of the current study was to determine the demographic characteristics and risk factors associated with male urinary incontinence (UI) and to assess the effectiveness and the effect on the quality-of-life of a pelvic floor muscle training (PFMT) protocol with electromyography-biofeedback (EMG-BFB) with surface electrodes. A prospective, quas...

Context: Transcutaneous electrical nerve stimulation (TENS) is a promising therapy for non-neurogenic lower urinary tract dysfunction and might also be a valuable option in patients with an underlying neurological disorder. Objective: We systematically reviewed all available evidence on the efficacy and safety of TENS for treating neurogenic lower...

Context: Impaired sexual function has a significant effect on quality of life. Various patient-reported outcome measures (PROMs) are available to evaluate sexual function. The quality of the PROMs to be used for neurologic patients remains unknown. Objective: To systematically review which validated PROMs are available to evaluate sexual functio...