Bapela Johanna

University of Pretoria | UP · Department of Plant and Soil Sciences

Ethnopharmacological relevance The Vha-Venda people of South Africa use Pappea capensis EckI & Zeyh. (Sapindaceae) twigs to treat malaria and its related symptoms. Aim of study The main aim of this study was to evaluate the antiplasmodial and cytotoxic activity of P. capensis extracts and chromatographic fractions. Spectroscopy analysis was conduc...

Inflammation associated with sexually transmitted infection (STIs) often results from delayed diagnosis or treatment, and may result in life-threatening complications. The root or stem bark of plants selected in this study are used by traditional healers in the management of STIs and to treat the associated inflammation. This study evaluated the an...

Ethnopharmacological relevance: The Vha-Venda people living in rural areas of Limpopo Province of South Africa regularly use traditional plant-based medicines to treat malaria. In our earlier publication, twenty indigenous plant species used to treat malaria or its symptoms by Vha-Venda people were evaluated for antiplasmodial activity. The main o...

In vitro screening of forty extracts prepared from selected South African plant species was conducted against Leishmania donovani (MHOM-ET-67/L82). Crude plant extracts were also subjected to an antiproliferative bioassay in an attempt to determine their potential lethality or safe therapeutic application against rat skeletal myoblast L6 cells. Of...

The effect of Nitrogen: Phosphorus: Potassium (NPK) (2:1:2 (44)) fertilizers on growth, accumulation of bioactive naphthoquinones (shinanolone, 7-methyljuglone, diospyrin, isodiospyrin and neodiospyrin) and antimycobacterial activity was investigated in seedlings of Euclea natalensis (Ebenaceae) grown in shadehouse and in field conditions. Seedling...

Seasonal variation of naphthoquinones was investigated from eleven wild plants of Euclea natalensis A.DC. subsp. natalensis belonging to the same population. The study was carried out in Tembe National Park, KwaZulu-Natal, South Africa. Quantitative analysis of bioactive naphthoquinones (shinanolone, 7-methyljuglone, diospyrin, isodiospyrin and neo...

A correlation between plant growth and accumulation of naphthoquinones (shinanolone (1), 7-methyljuglone (2) and diospyrin (3)) was investigated in seeds and seedlings of Euclea natalensis A.DC. In this study, the seeds represented the first stage whereas the second seedling stage was defined as the stage, when the radicles were about 6 cm in lengt...