Baoqiang Li

Harbin Institute of Technology | HIT · School of Materials Science and Engineering

Carbon dots/hydroxyapatite filler could have the reactive oxygen species (ROS) scavenging ability of CDs and the mechanical property improvement ability of hydroxyapatite. Carbon dots (CDs) not only have optical fluorescence by its physical property, but also regulates ROS by its biological property and had the binding ability of calcium ions by it...

Inside Front Cover In article number 2200637, Li, Li, and co‐workers reported N‐doped carbon dots derived carbon substrates containing N‐doped sp2/sp3 carbon interfaces to improve the hydrogen evolution reaction activity and stability of Ru. The existence of sp2/sp3 carbon interfaces contributed to boosting the hydrogen evolution reaction performan...

The bacterial colonization and poor osseointegration of Ti implants significantly compromise their applications in load-bearing bone repair and replacement. To endorse the Ti with both excellent bioactivity and antibacterial ability, we developed a microarc oxidation coating that was modified uniformly by hydroxyapatite (HA) nanodots arrays and loa...

The structure and properties of the carrier significantly affect the catalytic activity of the active centers for supported electrocatalysts. Therefore, elaborate design and regulation of the physicochemical properties of carbon carriers are essential to improve the activity and stability of the carbon‐supported ruthenium‐based catalysts. Herein, e...

Carbon dots (CDs) have been widely applied in metal ion recognition and detection, which makes them promising in the fields of environmental monitoring and biomedical science. However, CDs usually contain multiple functional groups that have different affinities for metal ions, so the relationship between CDs and recognized metal ions is ambiguous,...

The exploitation of ingenious strategies to improve the activity and stability of ruthenium (Ru) is crucial for the advancement of Ru-based electrocatalysts. Vacancy engineering is a typical strategy for modulating the catalytic activity of electrocatalysts. However, creating vacancies directly into pure metallic Ru is difficult because of the extr...

Reasonable design and facile synthesis of high-efficiency non-noble electrocatalysts for hydrogen evolution reaction (HER) in water splitting are crucial for renewable and clean energy technologies. Increasing the number of active sites via nanostructuring is a fundamental method to promote the HER activity of the catalysts. However, the balance be...

This research investigates a microwave transduction-based humidity sensor that is a promising candidate for real-time clinical healthcare applications and green miniaturized wearable electronic devices. Optimization of sensing material, sensing platform, and device fabrication techniques produces a carbon dots (CDs)-decorated metal organic framewor...

Target-oriented synthesis of multifunctional carbon dots with high synthetic yield is still a challenge. Herein, the acrylamide (AM) and acrylic acid (AA) which containing unsaturated carbon–carbon double bonds (CC) and different functional groups were chosen as switches for the directional synthesis of carrot derived carbon dots with water-solubil...

Injectable chitosan hydrogels exhibit excellent biological properties for application in biomedical engineering, however most of these hydrogels have limited applicability because “Swelling” can induce volume expansion of conventional hydrogels implanted in the body damages the surrounding tissues. Here, we report a new “Nonswelling” pentenyl chito...

Numbers of UV crosslinkable chitosan hydrogels through chemical modification had drawn increasing attention, however most of these chitosan hydrogels lost the pH-responsive performance because plenty of amino groups (‒NH2) in chitosan were consumed by reacting with other functional groups. To construct a pH-responsive UV-crosslinkable chitosan hydr...

To reveal the formation mechanism of new bone tissues induced by the multilayer titania coating with silicon-doped hydroxyapatite (Si-HA), plasma electrolyte oxidation (PEO) and microwave steam- hydrothermal treatment (MG) were performed to form Si-HA nanorods rapidly on the PEO coating. In the present work, the length and diameter of Si-HA nanorod...

Massive bleeding and wound infection after tissue trauma are the major dangerous factors of casualties in disasters; hence, first‐aid supplies that can greatly achieve wound closure and effectively control the hemorrhage and infection are urgently needed. Although existing tissue adhesives can adhere to the tissue surfaces and achieve rapid wound c...

In article number 2001820, Feng Xu and co‐workers report a multifunctional hydrogel‐based liquid bandage (LBA) for trauma emergency; the resulting photo‐responsive chitosan‐based hydrogel harvests robust adhesive, hemostatic, and antibacterial performances as a first‐aid tissue adhesive. LBA is simply prepared without any extraneous photo‐initiator...

Osteoclasts are the main cells of normal bone remodeling and pathological bone destruction in vivo. Overactivation of osteoclasts can lead to osteolytic diseases including breast cancer bone tumors, arthritis, aseptic loosening of orthopedic implants and Peget's disease. Excessive reactive oxygen species is the main cause of osteoclast overactivati...

In this work, we reported a novel and effective cancer treatment strategy by fabricating carbon dot (CD)-polyethylenimine (PEI)-doxorubicin (DOX) antitumor drug complexes from a combination of PEI-passivated CDs (CD-PEI) and DOX. CD-PEI was synthesized by the one-step microwave hydrothermal carbonization of a mixture of glycerol and PEI-25k, enabli...

Stimuli‐responsive chitosan (CS) hydrogels exhibit great potential for drug delivery and tissue engineering; however, the structure of these stimuli‐responsive CS hydrogels, such as dual pH‐ and thermo‐responsive hydrogels, is difficult to control or needs additional crosslinking agents. Here, a new dual pH‐ and thermo‐responsive hydrogel system is...

Hydrogel materials with exceptional mechanical properties at high water content are crucial need for practical applications in various fields. However, achieving a hydrogel possessed splendid mechanical performance with well trade-off between tensile strength and toughness is highly demanded due to the mechanical weakness of conventional hydrogel....

Hydrogels have been attracting great attention on account of their soft and wet nature, but inherently poor and unbalanced mechanical performance severely limits their applications. Herein, we reported a strategy to fabricate polyacrylamide/chitosan/montmorillonite nanocomposite hydrogels by simultaneously introducing lamellar montmorillonite and c...

Nanostructured metal oxides have shown outstanding promise for electrochemical energy storage, but are usually limited to low rate capability and poor cycling performance caused by irregular shapes and aggregation of nanoparticles at high mass loading (>1 mg cm⁻²). To solve these problems, we report the design of a novel Mn3O4 tetragonal bipyramid...

A high-performance multilayer coating with the external, flexible and silicon-doped hydroxyapatite (Si-HA) nanorods was designed using bionics. Plasma electrolytic oxidation (PEO) and microwave hydrothermal (MH) method were used to rapidly deposit this multilayer coating on a titanium (Ti) substrate, applied for 5 and 10 min, respectively. The bioa...

Rapid and high efficient synthesis of carbon dots is crucial problem for scalable synthesis and practical biomedical or environmental application. However, synthesis of carbon dots still has the challenges, such as long reaction time of hydrothermal carbonization and low synthetic yield of rapid microwave carbonization. To develop rapid and high-yi...

In order to enhance the bioactivity of the microarc oxidation (MAO) coating on titanium (Ti), a rapid modification technique of microwave hydrothermal (MH) treatment was used to form the dense, uniform and abundant hydroxyapatite (HA) crystals on the MAO coating surface. During the MH treatment, the calcium (Ca) and phosphorus (P) elements were mig...

A bioactive coating with the outwards growth of the uniform and abundant hydroxyapatite (HA) crystals was quickly fabricated on titanium (Ti) by microarc oxidation (MAO) and microwave hydrothermal (MH) treatment. The MAO coating consisted of a few of TiO 2 nanocrystals and lots of amorphous phase containing Ca, P, Si, Ti and O. The MH treating time...

Hyperbranched polysiloxane (HSi) molecules with tunable molecular structure were synthesized and served as a novel crosslinker for fabricating polyacrylamide/chitosan (PCH) hydrogels. Various characterizations demonstrated that HSi molecules with tunable bi-functional vinyl and epoxy groups were successful prepared and utilized to optimize the netw...

To improve the bioactivity and antibacterial ability of Zn-incorporated microarc oxidation (MAO-Zn) coating, the MAO-Zn coating was modified by hydrothermal treatment with deionized water (MAO-Zn-HT-0) and 5 mol/L NH3·H2O solution (MAO-Zn-HT-5). The hydrothermal treatment had a significantly effect on the structure, element and phase compositions o...

As one of important biomaterials for localized drug delivery system, chitosan hydrogel still exist several challenges, including poor mechanical properties, passive drug release behavior and lack of remote stimuli response. To address these challenges, a facile in-situ hybridization method was reported for fabricate tough magnetic chitosan hydrogel...

Manganese(II,III) oxide (Mn3O4) with various shapes including square prisms, polyhedra and tetragonal bipyramids are selectively synthesized with the mediation of fatty acids at nanoscale (<20 nm). Among all nanostructures, Mn3O4 tetragonal bipyramids show the largest gravimetric capacitance of 304 F g⁻¹ with excellent rate capability and long-term...

The nano brushite/TiO2 nanotubes composited coating with doubled layer structure was fabricated on titanium (Ti) by the multi-step treatments including sandblasting, acid etching, anodic oxidation and electrochemical deposition. The bonding strength of the brushite coating on Ti surface was improved by pre-treatment of the sandblasting, acid etchin...

Nitrogen and oxygen enriched hierarchically porous carbons (NOHPCs) derived from biomass have been successfully prepared by rapid microwave carbonization coupled with molten salt synthesis method in only 4 min. ZnCl2 plays important roles as microwave absorber, chemical activation agent and porogen in this process. NOHPC-1:10 sample possesses the m...

N-doped porous carbon with uniformly dispersed CoZn alloy nanoparticles is synthesized through pyrolysis of bimetallic zeolitic imidazolate framework containing Zn and Co elements. The surface area, pore size distribution and graphitization of the composites can be modulated easily by changing the molar ratio of Zn and Co of the zeolitic imidazolat...

Oxidative damage induced by accumulation of excessive reactive oxygen species (ROS) could result in increased chronic inflammation and thus ageing and age-related diseases. Carbonaceous nanodrug holds great promise for ameliorating age-related diseases, where it is necessary to develop ultrahigh-yield synthesis of such nanodrug. To improve the synt...

Visual in vivo degradation of hydrogel by fluorescence-related tracking and monitoring is crucial for quantitatively depicting the degradation profile of hydrogel in a real-time and non-invasive manner. However, the commonly used fluorescent imaging usually encounters limitations, such as intrinsic photobleaching of organic fluorophores and uncerta...

We have demonstrated a rapid and facile approach for preparing nitrogen doped and hierarchically porous carbons (NHPCs) using renewable chitosan as precursor via microwave carbonization in only 10 min. In microwave carbonization, ZnCl2 impregnated in chitosan hydrogel serves as microwave absorber, chemical activation agent and porogen. The porous t...

A new diarylethene–rhodamine derivative (1O) has been synthesized. It displayed colorimetric and fluorometric sensing abilities toward Cu²⁺ in CH3CN-H2O (4/1, v/v) solution, The fluorescence and absorbance detection limits for Cu²⁺ were calculated to be 0.31 μM and 0.28 μM, respectively. More importantly, the 1O-Cu²⁺ complex showed highly selective...

The sub-microporous microarc oxidation (MAO) coating covered Ti implant with micro-scale gouges has been fabricated via a multi-step MAO process to overcome the compromised bone-implant integration. The as-prepared implant has been further mediated by post-heat treatment to compare the effects of –OH functional group and the nano-scale orange peel-...

Amorphous microarc oxidation (MAO) coating containing Ca, P, Si and Na elements on Ti substrate has been heat treated in different atmospheres (air or argon) to adjust the phase composition, surface structure and bioactivity. After heat treatment in air at 800 °C for 1 h, the coating consists of anatase, rutile and CaTi4(PO4)6, with almost unchange...

The recognition and sensing of ions have attracted growing attention because of the important role played by ions in biological, industrial and environmental processes. However, many sensors can only detect a single ion. We report here a rhodamine-based sensor with functions of dual ion detection. It displays a quick colorimetric and fluorometric s...

Photoluminescent carbon nanodots (CNDs) have offered considerable potential to be used in biomedical and environmental fields including live cell imaging and heavy metal ion detection due to their superior quantum emission efficiencies, ability to be functionalized using a variety of chemistries and apparent absence of toxicity. However, to date, s...

To promote bone regeneration in vivo using critical-size calvarial defect model, hybrid hydrogel was prepared by mixing chitosan with hydroxyapatite (HA) and ultraviolet (UV) irradiation in situ. The hydrosoluble, UV-crosslinkable and injectable N-methacryloyl chitosan (N-MAC) was synthesized via single-step N-acylation reaction. The chemical struc...

This work was to improve the bioactivity of biomedical titanium (Ti) through constructing a bioactive surface with micro/nano-topography on Ti. Firstly, Ti plates were sandblasted, acid etched and anodized (SBAO) to obtain the controlled micro/nano-topography. And then, heat treatment was used to change the amorphous phase of Ti oxide nanotubes to...

Natural and biodegradable chitosan with unique amino groups has found widespread applications in tissue engineering and drug delivery. However, its applications have been limited by the poor solubility of native chitosan in neutral pH solution, which subsequently fails to achieve cell-laden hydrogel at physiological pH. To address this, we incorpor...

The microarc oxidation (MAO) coating covered pure Ti plates are steam-hydrothermally treated in autoclaves containing NaOH solutions with different concentrations of 0, 0.001, 0.01, 0.1 and 1mol·L(-1). Due to the composition of Ti, O, Ca, P, Si and Na elements in the MAO coating, anatase and hydroxyapatite (HA) crystals are generated from the previ...

A bioactive coating containing Ca, P, Si and Na elements with porous surface structure has been fabricated on titanium (Ti) plate by a three-step microarc oxidation. Randomly distributed gouges (80~200 μm) have been observed from the conformal MAO coating (with micro-scale pore size of 0.6~2μm in morphology) covered Ti surface which exhibits double...

H2Ti5O11•H2O nanorod arrays deposited titanium (Ti) surface has been fabricated via a hybrid technique of microarc oxidation (MAO) and chemical treatment. After the MAO treatment, amorphous phase composed porous coating containing Ca, P, Si and Na elements is formed on Ti surface. At the beginning of the chemical treatment, the elements of Ca, P, S...

The Ca, P, Si and Na incorporated bioactive coatings with double porous structure in macro (50–1000 μm) and micro (0.6–2.0 μm) scales have been successfully formed on Ti surface by a two-step treatment via microarc oxidation (MAO). The results reveal that the microarc oxidation and NO3− ion corrosion activated by plasma are the two key factors for...

Bioactive amorphous phase/TiO2 nanocrystal (APTN) composite coatings were fabricated by microarc oxidation (MAO) on Ti. The APTN coatings are composed of much amorphous phase with Si, Na, Ca, Ti and O elements and a few TiO2 nanocrystals. With increasing applied voltage, the micropore density of the APTN coating decreases and the micropore size of...

Sphene–titanium oxide composite coatings are prepared by a hybrid technique of microarc oxidation (MAO) and heat treatment on titanium. The average roughness of the MAO coating increases after heat treatment due to the crystallization and crystal growth of the MAO coating. The wetting ability, roughness, phase composition and surface topological st...

Macroporous Ti with macropores in size of 50-400 μm are prepared by sintering Ti microbeads with different diameters of 100, 200, 400 and 600 μm. Bioactive microarc oxidation (MAO) coatings with micropores in size of 2-5 μm are prepared on the macroporous Ti. The MAO coatings are composed of few TiO2 nanocrystals and lots of amorphous phase with Si...

The amorphous phase/TiO2 nanocrystals (APTN) composited coatings were prepared on Ti implants for biomedical applications. The Ti implants without and with the APTN composited coatings both do not cause any adverse effects after implantation into the rabbit tibia. The osseointegration of Ti implants after covering the APTN coatings is improved pron...

The microarc oxidation (MAO) was used to prepare TiO2 based coating containing Si, Ca and Na elements (SCN) on porous titanium sintered with different sizes of titanium beads. The chemical states of elements and apatite-forming ability of MAO coatings were investigated. The effect of titanium beads diameter on the chemical states of Ca and Si of MA...

Porous titanium was prepared by pressureless sintering of titanium beads with diameters of 100, 200, 400 and 600μm. The results indicated that the mechanical properties of porous titanium changed significantly with different bead diameters. Plastic deformations such as necking phenomenon and dimple structure were observed on the fracture surface of...

Porous titanium was prepared by vacuum sintering titanium beads with diameters of 100, 200, 400 and 600 mu m on titanium plate at temperature 1723 K for 2 h. Then TiO2-based coatings containing Si, Ca, Na (SCN) elements were fabricated by micro-arc oxidation (MAO) on the porous titanium. The results showed that the surface morphology, SCN concentra...

To address the high risk of postoperative infectious complications of bone implants and lack of the osteoinductive capacity of chitosan, the first line anti-tuberculosis drug rifampin (RFP) loading biomimetic bone structure chitosan/apatite composites (CS/AP) with sustained drug release were prepared by biomineralization which was achieved by soaki...

PPFBS modified MCM-41 was synthesized and the effect of hydrolysis time was investigated. The thermal decomposition of PPFBS/MCM-41 was also investigated. The XRD and TEM results indicate that the mesoporous layer spacing is 4.193 nm. With the increase of hydrolysis time, the degree of ordering of MCM-41 is improved. Excellent MCM-41 can be synthes...

In situ synthesis and hydrothermal carbonization were combined and carbon coated magnetite nanoparticles was synthesized. Its crystal structure, morphologies and magnetic property were investigated. XRD results indicate that chitosan coated magnetite nanoparticles (CS-MNP) are obtained via in situ synthesis. After hydrothermal carbonization, C-MNP...