Banu Onaral

Banu Onaral
Drexel University | DU · School of Biomedical Engineering, Science and Health Systems

About

191
Publications
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Publications

Publications (191)
Technical Report
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OBJECTIVES This document aims at providing an overview of the existing and developing standards in the field of neurotechnologies for brain‐machine interfacing. It is mainly focused on systems that provide a closed‐loop interaction with artificial devices based on information extracted from measures of the activity in the nervous systems. In additi...
Article
Full-text available
The use of serious game tools in training of medical professions is steadily growing. However, there is a lack of reliable performance assessment methods to evaluate learner’s outcome. The aim of this study is to determine whether functional near infrared spectroscopy (fNIRS) can be used as an additional tool for assessing the learning outcome of v...
Article
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Control of attention is thought to be specifically impaired in schizophrenia due to abnormal function in the prefrontal cortex (PFC). The PFC plays a critical role in the identification of relevant stimuli and the development of appropriate biases for the identified signals, including selection of an appropriate attentional ‘zoom’. We examined how...
Chapter
Serious game modules enhance knowledge and performance by offering participants to control the content and to arrange the suitable time for learning. Virtual Reality (VR)- based serious gaming modules are used as a complimentary tool for simulation based medical trainings and an emerging method to potentially replace lecture-based learning by enabl...
Article
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Background: The capacity for TMS to elicit neural activity and manipulate cortical excitability has created significant expectation regarding its use in both cognitive and clinical neuroscience. However, the absence of an ability to quantify stimulation effects, particularly outside of the motor cortex, has led clinicians and researchers to pair no...
Data
Detailed list of stimulation parameters and qualitative results for all studies investigating the effects of stimulation on task.
Data
Detailed list of stimulation parameters and qualitative results for all studies investigating stimulation at rest.
Article
Full-text available
Timing of the intervention for intracranial hematomas is critical for its success, specifically since expansion of the hemorrhage can result in debilitating and sometimes fatal outcomes. Led by Britton Chance, we and an extended team from University of Pennsylvania, Baylor and Drexel universities developed a handheld brain hematoma detector for ear...
Chapter
Functional Near-Infrared Spectroscopy (fNIRS) is a wearable and portable brain monitoring technology that tracks and monitors the cortical hemodynamic response using near infrared light sources and detectors placed over the scalp. fNIRS measures the changes of cortical deoxygenated hemoglobin (deoxy-Hb) and oxygenated hemoglobin (oxy-Hb) concentrat...
Chapter
Full-text available
Math anxiety is a problem that faces most people in their everyday life. Past research suggests that math anxiety can lead consumers to make errors in numerical computations. In this study, we utilized brain-based measures for the assessment of math anxiety in relationship to price perceptions. Functional near-infrared spectroscopy (fNIRS) from the...
Article
Full-text available
Transcranial magnetic stimulation (TMS) is a noninvasive method used to excite or inhibit cortical activity for experimental, diagnostic, and therapeutic interventions. However, nonmotor regions of the brain targeted in TMS therapies, such as the dorsolateral prefrontal cortex (DLPFC), offer no extrinsic response to stimulation, resulting in a need...
Article
Functional Near Infrared Spectroscopy (fNIRS) is an emerging neuroimaging technique that utilizes near infrared light to detect cortical concentration changes of oxy-hemoglobin and deoxy-hemoglobin non-invasively. Using light sources and detectors over the scalp, multi-wavelength light intensities are recorded as time series and converted to concen...
Article
Full-text available
The present study investigates brain-to-brain coupling, defined as inter-subject correlations in the hemodynamic response, during natural verbal communication. We used functional near-infrared spectroscopy (fNIRS) to record brain activity of 3 speakers telling stories and 15 listeners comprehending audio recordings of these stories. Listeners’ brai...
Article
Full-text available
The present study investigates brain-to-brain coupling, defined as inter-subject correlations in the hemodynamic response, during natural verbal communication. We used functional near-infrared spectroscopy (fNIRS) to record brain activity of speakers telling stories and listeners comprehending audio recordings of these stories. Listeners' brain act...
Conference Paper
Full-text available
The development of cognitive task battery applications for rehabilitation in telemedicine is a rapidly evolving field, with several tablet or web based programs already helping those suffering from working memory dysfunction or attention deficit disorders. However, there is little physiological evidence supporting a measurably significant change in...
Article
Our results illustrate the enhanced functional connectivity (FC) between motor-related brain regions and high-level cognitive brain regions during the transition period between rest and hand movements. These results suggest that the sensorimotor network is interacting with prefrontal areas during the transition period to maintain the preparation st...
Conference Paper
Full-text available
Simultaneously recorded electroencephalography (EEG) and functional near infrared spectroscopy (fNIRS) measures from sixteen subjects were used to assess neural correlates of a letter based n-back working memory task. We found that EEG alpha power increased and prefrontal cortical oxygenation decreased with increased practice time for the high memo...
Article
Full-text available
This review paper introduces the emerging technology of optical brain imaging, also known as functional near infrared (fNIR) spectroscopy, and discusses its potential role in enhancing theory and methodology used in MIS research. We discuss basic fNIR principles including the technique’s safe and portable nature, which allows ambulatory brain activ...
Patent
Full-text available
Disclosed are methods and devices for measuring a state of anesthesia in a noninvasive manner. Optical techniques may be used to measure changes in a functional near-infrared (fNIR) signal, where the fNIR signal is received in response to directing wavelengths of light in a near-infrared range on a patient. The optical density change may be used to...
Article
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Neuroimaging technologies, such as functional near-infrared spectroscopy (fNIR), could provide performance metrics directly from brain-based measures to assess safety and performance of operators in high-risk fields. In this paper, we objectively and subjectively examine the cognitive workload of air traffic control specialists utilizing a next-gen...
Article
Full-text available
In this case study, an early-career electrical engineer interviews an established translational biomedical engineer. The discussion covered topics such as challenges associated with the merging of fundamental engineering science with the pursuit of clinically informed research, how best to train engineering students for future innovation, and how t...
Article
Full-text available
Cognitive impairment in amyotrophic lateral sclerosis (ALS) is associated with cortical changes beyond the motor cortex. The overall goal of this project is to determine if task induced hemodynamic changes detected by functional near infrared (fNIR) spectroscopy from the anterior prefrontal cortex (PFC) has discriminant validity across ALS (n = 17)...
Chapter
The use of unmanned aerial vehicles (UAVs) is expected to increase exponentially over the next few years. UAV ground operators are required to acquire skills quickly and completely, with a level of expertise that builds the operator’s confidence in his/her ability to control the UAV under adverse conditions. As UAVs are held to increasingly higher...
Article
Full-text available
Functional near infrared spectroscopy (fNIRS) is a non-invasive, safe, and portable optical neuroimaging method that can be used to assess brain dynamics during skill acquisition and performance of complex work and everyday tasks. In this paper we describe neuroergonomic studies that illustrate the use of fNIRS in the examination of training-relate...
Conference Paper
Full-text available
An asynchronous P300-based brain computer interface (BCI) allows users to operate the BCI at their own pace by being able to detect a user's engagement. In our previous work, band powers has been shown to be able to provide additional information for characterizing user engagement and yielded better performance compared to the use of only the ampli...
Article
The construct of working memory and its reliance on dorsolateral prefrontal cortex (DLPFC) have been the focus of many studies in healthy subjects and in clinical populations. However, transfer of knowledge gained from cognitive science studies to clinical applications can be a challenging goal. This scarce cross-dissemination may be partially due...
Conference Paper
Full-text available
Synthetic speech has a growing role in human computer interaction and automated systems with the emergence of ubiquitous computing such as smart phones, car multimedia control and navigation systems. Cognitive processing costs associated with comprehension of synthetic speech relative to comprehension of natural speech have been demonstrated with b...
Conference Paper
Full-text available
Next generation brain computer interfaces (BCI) are expected to provide robust and continuous control mechanism. In this study, we assessed integration of optical brain imaging (fNIR: functional near infrared spectroscopy) to a P300-BCI for improving BCI usability by monitoring cognitive workload and performance. fNIR is a safe and wearable neuroim...
Conference Paper
Full-text available
Functional near infrared (fNIR) spectroscopy is a field-deployable optical neuroimaging technology that provides a measure of the prefrontal cortex’s cerebral hemodynamics in response to the completion of sensory, motor, or cognitive tasks. Technologies such as fNIR could provide additional performance metrics directly from brain-based measures to...
Conference Paper
Full-text available
There is growing evidence that there are functional changes in the brains of individuals with substance use disorders. Numerous studies utilizing functional magnetic resonance imaging (fMRI) have shown that drug cues elicit increased regional blood flow in reward-related brain areas among addicted participants that is not found among normal control...
Conference Paper
Full-text available
The role of practice is crucial in the skill acquisition process and for assessments of learning. In this study, we used a portable neuroimaging technique, functional near infrared (fNIR) spectroscopy for monitoring prefrontal cortex activation during learning of spatial navigation tasks throughout 11 days of training and testing. Two different tas...
Article
Full-text available
Endoscopic procedures performed in the United States routinely involve the use of conscious sedation as standard of care. The use of sedation reduces patient discomfort and anxiety while improving the technical quality of the procedure, and as a result, over 98% of clinicians have adopted the practice. The tremendous benefits of sedation are offset...
Patent
Full-text available
Functional near-infrared (fNIR) neuroimaging is used to assess credibility, detect deception, and implement a query methodology for determining deception via neuroimaging. Oxygenation levels of portions of the brain are imaged via fNIR spectroscopy and utilized to determine if the subject is telling a lie or a truth. In an example configuration, ox...
Article
Full-text available
Data indicated that dyslexic individuals exhibited difficulties on tasks involving Working Memory (WM). Previous studies have suggested that these deficits stem from impaired processing in the Phonological Loop (PL). The PL impairment was connected to poor phonological processing. However, recent data has pointed to the Central Executive (CE) syste...
Article
![Figure][1] Banu Onaral Our instincts as well as data ([ 1 ][2]) suggest that the conversion of scientific knowledge into social good and economic value creates well-being, prosperity, and peace, transcending cultural, disciplinary, or national boundaries. Forging innovation alliances that
Article
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In this study, a Brain Computer Interface (BCI) based on the P300 oddball paradigm has been developed for spatial navigation control in virtual environments. Functionality and efficacy of the system were analyzed with results from nine healthy volunteers. Each participant was asked to gaze at an individual target in a 3×3 P300 matrix containing dif...
Article
Full-text available
Brain-computer interface (BCI) provides patients suffering from severe neuromuscular disorders an alternative way of interacting with the outside world. The P300-based BCI is among the most popular paradigms in the field and most current versions operate in synchronous mode and assume participant engagement throughout operation. In this study, we d...
Article
Full-text available
Recent neuroimaging studies have implicated prefrontal and parietal cortices for mathematical problem solving. Mental arithmetic tasks have been used extensively to study neural correlates of mathematical reasoning. In the present study we used geometric problem sets (tangram tasks) that require executive planning and visuospatial reasoning without...
Article
The dual route model (DRM) of reading suggests two routes of reading development: the phonological and the orthographic routes. It was proposed that although the two routes are active in the process of reading; the first is more involved at the initial stages of reading acquisition, whereas the latter needs more reading training to mature. A number...
Conference Paper
Full-text available
This study used functional near-infrared spectroscopy (fNIRs) to test the hypothesis that non-treatment seeking alcohol-dependent participants (NTSA) would show greater response in dorsolateral prefrontal cortex (DLPFC) to alcohol cues than recovering alcoholics (RA; sober 90-180 days) or social drinkers. Opposite predictions were made for response...
Conference Paper
This study focuses on the positional effects on hemodynamic changes monitored by the functional near infrared (fNIR) spectroscopy. The motivation behind this exploratory study is to provide a standard approach for a number of bedside, and postural applications where the body-head position can influence the fNIR signal readings. By administering two...
Article
Full-text available
Artifact removal from physiological signals is an essential component of the biosignal processing pipeline. The need for powerful and robust methods for this process has become particularly acute as healthcare technology deployment undergoes transition from the current hospital-centric setting toward a wearable and ubiquitous monitoring environment...
Chapter
Full-text available
This study used functional near-infrared spectroscopy (fNIRs) to test the hypothesis that non-treatment seeking alcohol-dependent participants (NTSA) would show greater response in dorsolateral prefrontal cortex (DLPFC) to alcohol cues than recovering alcoholics (RA; sober 90-180 days) or social drinkers. Opposite predictions were made for response...
Conference Paper
Full-text available
The efficiency and safety of many complex human-machine systems are closely related to the cognitive workload and situational awareness of their human operators. In this study, we utilized functional near infrared (fNIR) spectroscopy to monitor anterior prefrontal cortex activation of experienced operators during a standard working memory and atten...
Conference Paper
Full-text available
The efficiency and safety of many complex human-machine systems such as Unmanned Aerial Vehicle (UAV) are closely related to the cognitive workload and situational awareness of their operators. Subjective operator reports, physiological and behavioral measures are not reliably sensitive for monitoring cognitive overload. Drexel's Optical Brain Imag...
Conference Paper
Full-text available
An accurate assessment of mental workload and expertise level would help improve operational safety and efficacy of human computer interaction for aerospace applications. The current study utilized functional near-infrared spectroscopy (fNIR) to investigate the relationship of the hemodynamic response in the anterior prefrontal cortex to changes in...
Article
This study aimed to affirm the use of functional near-infrared spectroscopy (fNIR) in examining frontal lobe role during automatic (i.e., requires retrieval from long-term memory) and method-based (i.e., requires calculation) arithmetic processing. Adult university students (math difficulties [MD] and control) performed simple arithmetic calculatio...
Article
An accurate measure of mental workload in human operators is a critical element of monitoring and adaptive aiding systems that are designed to improve the efficiency and safety of human-machine systems during critical tasks. Functional near infrared (fNIR) spectroscopy is a field-deployable non-invasive optical brain monitoring technology that prov...
Article
Full-text available
In this paper we present an experimental study where we investigated neural correlates of visuospatial reasoning during math problem solving in a computer-based environment to exemplify the potential for conducting interdisciplinary research that incorporates insights from educational research and cognitive neuroscience. Functional near-infrared sp...
Article
Full-text available
MazeSuite is a complete toolset to prepare, present and analyze navigational and spatial experiments1. MazeSuite can be used to design and edit adapted virtual 3D environments, track a participants' behavioral performance within the virtual environment and synchronize with external devices for physiological and neuroimaging measures, including elec...
Article
Full-text available
fNIRS recordings are increasingly utilized to monitor brain activity in both clinical and connected health settings. These optical recordings provide a convenient measurement of cerebral hemodynamic changes which can be linked to motor and cognitive performance. Such measurements are of clinical utility in a broad range of conditions ranging from d...
Article
Full-text available
A brain computer interface (BCI) is a system that translates neurophysiological signals detected from the brain to supply input to a computer or to control a device. Volitional control of neural activity and its real-time detection through neuroimaging modalities are key constituents of BCI systems. The purpose of this study was to develop and test...
Conference Paper
The process of reading activates a large-scale neural network which includes different cortical brain regions. This network is thought to be age-dependent and changes throughout the process of reading acquisition. The frontal lobe is considered to be related to higher, executive, functions. We conducted a functional Near InfraRed Spectroscopy (fNIR...