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Bandana K. Thakur worked at the Department of Chemistry, Hemwati Nandan Bahuguna Garhwal University. Bandana does research in Phytochemistry, Medicinal Chemistry and Organic Chemistry. Their most recent publication is 'Synthesis, antibacterial screening and theoretical molecular properties prediction of hydantoin-chalcone conjugates'.
February 2008 - March 2011
- Isolation of phytoecdysteroids from Achyranthes aspera and A. bidentata and examine thier effect on bombyx mori l.
- Phytoecdysteroids, bombyx mori, Achyranthes aspera and A. bidentata
The potential of higher plants as a source of new drugs is still largely unexplored. Among the estimated 2.5-5 lakh plant species, only a small percentage has been investigated phytochemically and the fraction submitted to biological or pharmacological screening is even smaller. Cumulative studies have revealed that lauraceous plants, particularly...
Hydantoins and chalcones both are the privileged pharmacophores with significant importance in medicinal chemistry. A series of eleven hydantoin-chalcone conjugates was synthesized and virtually screened for its physico-chemical properties . Molinspiration and Osiris software were used for theoretical prediction of physic oc he mic al properties of...
In a search of new compounds active against cancer, synthesis of a series of C-5 curcumin analogues was carried out. The new compounds demonstrated good cytotoxicity against chronic myeloid leukemia (KBM5) and colon cancer (HCT116) cell lines. Further, these compounds were found to have better potential to inhibit TNF- α -induced NF- κ B activation...
Flavonoids are a group of low-molecular-weight polyphenolic compounds of plant origin. They exhibit a variety of biological activities such as anti-inflammatory, antioxidant, antiviral, and antitumor etc. Baicalein, is a bioactive flavone constituent of Scutellariae radix with a wide range of beneficial activities. But the poor solubility and disso...
Achyranthes bidentata is annual or perennial herb, which is widely used in the traditional and folk medicines. The seeds contain about 6.1% oil. The major fatty acid of seed oil was found to be arachidic acid (53.1%) followed by palmitic acid (20.8%) and oleic acid (20.5%). Eicosenic acid, linolenic acid, stearic acid and behenic acids were present...
Insects are an integral part of our system, constituting 72% of all animal species. Many insects and products of insect origin, are important in our daily lives such as silk, tasar, honey, beeswax, shellac, paints, dyes and medicines. Bombyx mori L., the silk worm, is an important economic insect since it is the producer of silk. It belongs to clas...
I am working on a lauraceaous plant. I extracted the leaves of the plant sequetially with petether, chloroform and methanol. I did CC of all extracts. in methanol extract, I was not able to isolate any promising fraction which could lead to a compound. So I tried to fractionate the methanol extract by other solvent (like ethyl acetate and butanol etc.) to reduce the complexity of extract. But when I dissolved the methanol extract in water more than 50% of extract was insoluble in water.
I want to know that what could be done with this water insoluble fraction. Can I isolate polysacchrides from this? Please suggest the methods for isolation of polysaccharides...