Bamidele Adewale Salau

Bamidele Adewale Salau
Redeemer's University · Department of Chemical Sciences

Dip (Public Health) BSc(Human Nutr) Msc (Human Nutr) PhD(Biochemistry)

About

51
Publications
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325
Citations
Introduction
Bamidele Adewale Salau currently works at the Department of Chemical Sciences, Redeemer's University. Bamidele does research in Nutritional Biochemistry. Their current project is 'Cyanogenic Glycosides Retention in Juiced and Blanched Leafy Vegetables Commonly Consumed in South-western Nigeria. '.
Additional affiliations
March 2011 - November 2013
Redeemer's University
Position
  • Professor (Full)
Description
  • I am currently working on the use of vegetables in moderating cardiovascular risk factors induced by high sucrose diet.
January 2000 - December 2000
Olabisi Onabanjo University Teaching Hospital
Position
  • Research Associate
Education
February 2001 - November 2010
Olabisi Onabanjo University
Field of study
  • Biochemistry

Publications

Publications (51)
Article
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The possible relevance of under-utilized vegetables for nutrition; has been reported in some studies. This study probed proximate, mineral and phytochemical properties three under-utilized traditional leafy vegetables; Solanum nigrum (SN), Cucurbita pepo (CP) and Crassocephalum crepidioides (CC). Standard methods were applied to determine proximate...
Article
Background and Objective: The role of sucrose in the biochemical derangement in many tissues/organs has been established. However, there is a dearth of information about its effect on mineral status in integumentary tissues such as hair, nail, and skin in male albino rats. This study investigated minerals response in some selected integumentary tis...
Article
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Background and Objective: Plantain is known as a rich source of several bioactive components yet there are several local claims on how those bioactive components could be promoted by employing fermentation. This study was set to investigate the effect of fermentation on the phytochemical constituents; exploring Fourier Transformer Infrared (FTIR) s...
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Background and Objective: Pesticides have been implicated in oxidative stress, which is associated with many disorders, including testicular dysfunction. This study, therefore, investigated the ameliorative effect of coconut oil (CCO) on male Wistar rats exposed to propanil (PPN), a commonly used herbicide. Materials and Methods: The study comprise...
Article
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Background and Aim: The present study evaluated the levels of some hepatic enzymes in the plasma of Nigerians affected with hematological malignancies, to determine if these enzymes could be established as predictors of possible metastasis to the liver, the degree of severity of the disease or prognostication of hematological malignancies. Material...
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Background The global increase in acceptance and use of herbal remedies in recent times is still accompanied with poor knowledge of their potential adverse effects and the toxicological implications of their use are underestimated. Methods Bon-santé Cleanser® (BSC), a polyherbal containing Anogeissus leiocarpus, Terminalia ivorensis, Massularia ac...
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Introduction: Current research effort at discovering effective anticataract agent is focus on evaluating Aldose reductase inhibition (ARI) capacities of medicinal plants and plant extracts. The present study was aimed at investigating the in vitro ARI activity of fractions of Lonchocarpus cyanescens leaves on partially purified AR from goat lens. M...
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Chromium is necessary for insulin function, nutrient uptake and regulation of major metabolism as well as boosting of immune system amongst others; available in vegetables, the cheapest source for the majority of people living in developing countries. Seven commonly consumed vegetables in south west Nigeria were collected from four major markets in...
Article
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Aim: We tested the hypothesis that administrations of methanolic extracts of Musa sapientum sucker (MEMS) with exercises attenuated hyperglycemia in alloxan-diabetic rats. Materials and methods: A total of 40 adult male rats were divided into equal eight groups. Normoglycemic Group A was Control. Alloxan (180 mg/kg, i.p.) was administered to rat...
Article
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Aim: Dearth of information exists on the phytochemistry and toxicity profile of ethanolic leaves extract of Lageneria breviflora in spite of the much touted medicinal efficacy of the plant. The present study qualitatively evaluated the phytochemical compositions as well as the toxicological effect of the ethanolic leaves extract of the plant. Study...
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Effects of various concentrations of sucrose diet were assessed on calcium status of thirty weanling male albino rats randomly divided into five equal groups as follows: G1 (baseline group); G2 (control group; rat chow only); G3, G4 and G5 (experimental groups; with energy supply from sucrose at 10, 20 and 30 percent respectively). The experimental...
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Abstract: Effect of methanolic extract of musa sapientum sucker (MEMSS) in indomethacin-induced ulceration in Wistar rats was investigated. Thirty albino rats (120-150g) were divided into six groups. Negative and positive control rats (group 1 and 2) received no treatment and indomethacin (50mg/kg) respectively. Group 3 rats received Omeprazole (0....
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Reports on the role of calcium on predisposition to cardiovascular disease have been rather inconsistent while studies on its interaction with other medications are ongoing. We therefore investigated the effect of separate and combine administration of calcium supplement with artemisinin-based combination drug on hepatic and serum lipid profile. Th...
Article
Effects of fluoride on the levels of Lipid peroxidation (LP) and antioxidant enzymes in the brain regions of protein undernourished (PU) and well-fed rats (WF) rats exposed to 100ppm fluoride in drinking water were investigated. The results indicate that the mean body weights and the total brain weights of PU rats as well as those given fluoride (b...
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Recently, there have been growing concerns over the reliance and safety of untested and unregulated plant remedies. Bridelia ferruginea is one of the herbal plants commonly used, of which chronic toxicity studies are yet to be examined. Sub-chronic toxicological effects of methanolic benth bark extract of bridelia ferruginea on biochemical indices...
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Saponin, a secondary plant metabolite acts as both antinutrient and antioxidant in humans. It is usually affected by different processing methods, majorly heating. Though, vegetables are usually subjected to processing before consumption, however, recent interest in vegetable juice is gaining ground among the populace without consideration to the l...
Article
We investigated anti-ulcer properties of Musa sapientum sucker in rats. Group I was control. Indomethacin (40mg/kg/ bodyweight) was orally administered to rats of Groups II - V for induction of ulcer. Four hours after administrations of the ulcerogen; 5, 10 and 20mg/kg/bodyweight of Musa sapientum sucker extract and 40mg/kg/bodyweight of Omeprazole...
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The effect of household preparation prior to consumption was assessed in five vegetables commonly consumed in Nigeria: Telfaria occidentalis, Celosia argentea, Amaranthus caudatus, Solanum macrocarpon and Talinum triangulare purchased from a local market in south-west Nigeria. Wholesomeness, colour, moisture and ascorbic acid content were determine...
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The involvement of sucrose and its amount in the causation of cardiovascular disease is still controversial and inconclusive. The two latest reports of WHO/FAO and Institute of Medicine of Food and Nutritional Board (IOM of FNB) on optimal level of sucrose consumption are at least contradictory; therefore the need to clarify the effect of different...
Article
This study investigated Lipid peroxidation status in twenty Nigerians; five (5) healthy subjects and 15 (fifteen) Haematological cancer patients; 5 affected with Chronic Myeloid leukaemia (CML), 5 (five) with Non-Hodgkin's Lymphoma and 5 (five) with Multiple Myeloma. Consents were sought and received from all participants used in the study. 10 mls...
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Bakeries in Ikenne Local Area of Ogun State, Nigeria, the home local council of the College of Health Sciences, Olabisi Onabanjo University, Remo Campus, Ikenne and Babcock University, llisan; were used to attenuate the possible exposure of students of the aforementioned institutions to potassium bromatc from bakeries product (a previously out-legi...
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Free radical and reactive oxygen species (ROS) have been implicated in contributing to growth retardation, diminished food efficiency and the process of ageing and disease. However, human beings protect themselves from these damaging compounds partly, by absorbing antioxidants from high antioxidants containing food. Forty-eight (48) weaned rats wer...
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Fruits and vegetables have been shown to contain vital components that moderate disease conditions. However, there is dearth of information of these effects in Africans diabetic subjects. Thus, we investigated the relative effect of fruits and vegetables on some selected heamorological factors associated with cardiovascular disease in diabetic subj...
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Automechanics are among the job professionals in proximity to diesel and gasoline exhaust whose components are known to be toxic. This raises serious public health concern. This study is a population-based-cross-sectional survey, set up to investigate the risk of cardiovascular and hepatic injury incurred by people engaged in work as mechanics. For...
Article
In the past few decades, there has been renewed interest on increase in intake of fruits and vegetables, owing to their numerous beneficial effects. The present study provides preliminary data on the ability of different fruits and vegetables grown and consumed in Ijebu North Local Government Area of Ogun State, Nigeria to concentrate iodine in the...
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Disproportion in intake of nutrient may lead to imbalance diet with resultant effects of malnutrition and its attendant’s problems. Although, there are reports indicating that uncontrolled intake of sucrose may cause different health disorders, sugar companies disagreed with these statements. This study was thus carried out in order to investigate...
Article
Full-text available
Effect of processing on iodine content of some selected plants food was investigated. Results show significant reduction (p < 0.05) in the iodine content of the processed food compared with the raw forms. The iodine value of 658.60 ± 17.2 μg/100g observed in raw edible portion of Discorea rotundata was significantly higher compared with the value o...
Article
Hydrocotyl bonariensis Comm. Ex Lam (Apiaceae) is being widely used in Western Nigeria in treating various symptoms of ophthalmic diseases; however scientific data in support of this medicinal use have not been reported. This study, investigated the efficacy of Hydrocotyl bonariensis leave extract in offering protection against experimental catarac...
Article
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Previous studies reported on relationship between chloroquine administration, insulin and glucose homeostasis, but the role of dietary fat and the combined effect of the drugs on liver function have not been exploited. The present study was set up to investigate the effect of combined administration of insulin and chloroquine on serum transferase a...
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Some selected staple foods: tubers, cereals, and legumes, grown, sold and consumed in Ijebu-North Local Government area, Nigeria were evaluated for their iodine content using standard methods. Among the tubers, Ipomea batata (sweet potatoe, red species) was observed to have the highest iodine content (311.33±8.52 µ µ µ µgI) while the least iodine v...
Article
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This study was carried out to investigate the cardiovascular effect of administration of antimalarial drugs amodiaquine and artesunate and the efficacy of Garcinia kola extract (kolaviron) in protecting against such possible effect. Thirty (30) adult male albino rats divided into six (6) groups were used in this study. Groups D, E and F were treate...
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The effect of kolaviron, a water extract of Garcinia Kola on hepatotoxicity induced by the antimalarial drug, amodiaquine was investigated. The effect was compared with that of artesunate, another antimalarial agent. Thirty (30) adult male rats divided into six (6) groups were used in the study. Groups D, E and F were treated with 100mg/Kg of the e...
Article
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Fruits and vegetables contain vital components such as potassium, antioxidants, vitamins and folic acid that might contribute to lowering blood pressure which is a major risk factor in cardiovascular disorders. However, the results of the few investigations on the correlation between intake of fruits and vegetables and cardiovascular disease have b...
Article
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Hyperlipidemia is a major risk factor in etiology of cardiovascular disease. Previous studies have shown association between vegetarian diet and low total serum cholesterol as well as LDL-cholesterol which is a pointer to low risk of cardiovascular disease. Dietary fiber, antioxidants and other classes of nutrients have been reported to ameliorate...
Article
Effect of combined administration of Insulin and Chloroquine on fasting blood glucose, total protein, creatinine and uric acid concentration were investigated in rats placed on diets high in fat and calcium (SP diet). Thirty-six (36) rats (grouped into six) were placed on different treatment: Grams A and B were fed with NP (normal diet) and SP diet...
Article
Full-text available
Studies on toxicity of galactose and its management have been largely concentrated on the lens. The present study compare the oxidative stress that occurred in various tissues of rats placed on dietary galactose and simultaneously administered with different doses of Hydrocotyl bonariensis leave extract. Male rats weanling rats placed on dietary ga...

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Projects (4)
Project
To determine the effect of sucrose on calcium and magnesium content of different tissues
Project
Abstract: Short term consumption of high sucrose diet has been associated with oxidative stress and impairment of antioxidant status on certain antioxidants. However, there is paucity of information on long term effect through consumption of sucrose d iet. Effect of sucrose rich diet was examined on weanling male albino rats weighing 56-63g. The rats were divided into four groups based on varying sucrose concentrations in their diets and were fed ad-libtum with different diets corresponding to their group label for a period of twelve weeks. Afterward, rats were sacrificed and plasma were prepared to assay for malondialdehyde, catalase, reduced glutathione, albumin and uric acid. The results show a significant decrease (p<0.05) in catalase activity and glutathione in all the experimental groups and significant increase (p<0.05) in uric acid and malondialdehyde level when compared to the control group. However, there was no significant effect on albumin level in all the groups. It can be concluded that sucrose consumption for a period of twelve weeks increases the generation of reactive oxygen species (ROS) and also impair the activity of catalase and the level of glutathione and uric acid. Thus, the effect on these parameters is accentuated as the energy from sucrose increases.