Bailey DeBarmore

Bailey DeBarmore
Johnson & Johnson | J&J

Doctor of Philosophy

About

25
Publications
1,054
Reads
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33
Citations
Citations since 2016
21 Research Items
33 Citations
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2016201720182019202020212022051015

Publications

Publications (25)
Article
Cardiovascular disease surveillance involves quantifying the evolving population‐level burden of cardiovascular outcomes and risk factors as a data‐driven initial step followed by the implementation of interventional strategies designed to alleviate this burden in the target population. Despite widespread acknowledgement of its potential value, a n...
Article
Full-text available
Introduction: Acute exacerbations of chronic obstructive pulmonary disease (AECOPDs) are important clinical events, with many patients experiencing multiple AECOPDs annually. The terms used in the literature to define recurring AECOPD events are inconsistent and may impact the ability to describe the true burden of these events. We undertook a sys...
Article
Introduction: Probability of survival after out-of-hospital cardiac arrest (OHCA) doubles when a bystander initiates cardiopulmonary resuscitation and uses an automated external defibrillator (AED) rapidly. National, state, and community efforts have increased placement of AEDs in public spaces; however, bystander AED use remains less than 2% in t...
Article
Full-text available
Population cardiovascular health, or improving cardiovascular health among patients and the population at large, requires a redoubling of primordial and primary prevention efforts as declines in cardiovascular disease mortality have decelerated over the past decade. Great potential exists for healthcare systems–based approaches to aid in reversing...
Article
Full-text available
Introduction Mitochondrial DNA copy number (mtDNA-CN) is a measure of mitochondrial dysfunction and is associated with diabetes in experimental models. To explore the temporality of mitochondrial dysfunction and diabetes, we estimated the prevalent and incident association of mtDNA-CN and diabetes. Research design and methods We assessed the assoc...
Article
Background: In United States (US) emergency departments (ED), ~80% of patients presenting with exacerbation of heart failure (HF) symptoms are admitted to the hospital. However, some patients are at low-risk of adverse outcomes and might be effectively managed as outpatients. While ED HF risk prediction tools guide admission or discharge decisions,...
Article
Background: Chronic kidney disease (CKD) and cardiovascular disease share similar risk factors, such as diabetes, hypertension, and dyslipidemia promoting atherosclerosis. Acute myocardial infarction (MI) presenting without chest pain is associated with higher case fatality compared to MI with chest pain. Patients with non-ST-elevation MI (NSTEMI)...
Article
Introduction: Recent research shows changing incidence rates of AMI by subtype (ST segment elevation [STEMI] and non-ST segment elevation [NSTEMI]), anatomical location, and severity. However, trends in AMI symptom presentation are less well examined. Not all AMI patients present with classic chest pain of cardiac origin. Presentation without cardi...
Presentation
Full-text available
Some outcomes are subject to a ceiling effect, where a substantial portion of participants score at the top of the instrument. We compared different analytic approaches to determine which had the greatest power in the presence of ceiling effect as well as effect measure modification or treatment effect heterogeneity.
Article
Setting: Researchers use several tools to measure functional status in stroke patients. Analyses often use simple linear models, which assume a common treatment effect regardless of stroke severity. However, patients with mild stroke or TIA may perform at the maximum of an instrument, or the ceiling. The presence of a so-called ceiling effect confl...
Article
Full-text available
Blood pressure (BP) variability is associated with progression to clinical atherosclerosis. The evidence is inconclusive if BP variability predicts cardiovascular outcomes in low-risk populations. The aim of this study was to analyze the association of 24-hour BP variability with coronary artery calcium (CAC) among a group of individuals without co...
Article
Introduction: In the United States, the rising number of adults with type 2 diabetes (T2D) is thought to be associated with the rise in obesity. Obesity may be associated with T2D through biologic pathways where excess weight strains the body’s metabolic machinery, such as mitochondria. Mitochondria are dynamic organelles whose regulation and funct...
Poster
Full-text available
Open abdomen patients are a hypermetabolic intensive care population; however, enteral feeding is often delayed until after fascial closure due to concerns of GI intolerance and postponed closure. We explored the association of enteral feeding in OA patients and days to fascial closure in a retrospective electronic medical record chart review.
Article
Full-text available
In 2010, older Americans were the least-active age group in the United States, with only 11% over the age of 65 meeting recommended amounts of activity. Similarly, 28% of adults over age 65 are obese. In the coming years, older Americans will not only make up a greater percentage of the US population than ever before, but the racial composition of...
Article
Full-text available
According to 2013 data, older Americans often eat a nutrient-poor and sometimes energy-deficient diet. An individual's diet, health, nutritional and medical history, nutritional status, and SES factors all play an important role in how supplementation and/or diet can optimize nutrition status. Given the importance that nutrition plays in the lives...
Poster
Full-text available
A key tool in obesity research is the use of metabolic research kitchens, which may benefit from incorporating technology into nutrition research services to reduced labor time and improve accuracy. ProNESSy is an optional add-on to ProNutra that can track food weights for multiple subjects and studies. We compared the NIH CC Metabolic Kitchen stan...

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Projects

Projects (6)
Project
The purpose of EPICODE is to share code used to conduct epidemiological methods. Its inspiration is 3-fold. 1. Straightforward isn't always straightforward 2. Teaching & Efficiency 3. Open Access Attitude -- 1. Straightforward isn't always straightforward You find yourself wanting to use the same analysis as a paper you found. The problem is that the method is described only as a single line. For example "We utilized logistic regression to estimate case fatality percentages adjusted for age and sex." You think, "simple enough". Then you realize it involves using logits and SE(logit) to predict the probabilities. And you're not so sure how to do that. 2. Teaching versus Efficiency Much of code sharing these days is in the form of macros and similar programs to expedite analysis. There's a gap from basic epidemiology methods implementation (2 x 2 tables, OR, regression) to more sophisticated methods (inverse probability weights, standardization). Many researchers call for more widespread use of these sophisticated methods, but we can't do that if we don't know how. 3. Open Access Attitude While many statistics journals encourage or require code and public data used to be shared with published articles, to request code remains at the behest of the reader reaching out to the corresponding author in most cases. Use our EPICODE project to share link your paper to your code, share your comments, questions, and solutions, and contribute by writing your own post at www.baileydebarmore.com/epicode.
Project
What are the best analytic approaches to handle ceiling effect in patient-reported outcomes in comparative effectiveness research?