Bader Faiyaz Zuberi

• MBBS, FCPS, FACG, AGAF
• Professor (Full) at Dow University of Health Sciences

The Hep-Net position paper comes at a significant time in the history of Metabolically Associated Fatty Liver Disease (MAFLD) due to the rapid rise in this disease entity in the past decade. Metabolically Associated Fatty Liver Disease, by its very name, encompasses several common metabolic disease entities, top among those being diabetes and obesi...

Objective: To compare frequency of caesarean section in singleton primary-para women induced at 39 week and its comparison with conventional management. The other objective was comparison of perinatal and neonatal outcomes. Method: Open random allocation study was conducted at Gynae/Obst Department JPMC during period from 1st June 2022 to 30th Sept...

OBJECTIVE: To determine the frequency of anemia in patients with newly diagnosed pulmonary Tuberculosis (PTB) presenting at Dr Ruth K M Pfau Civil Hospital Karachi (CHK). METHODOLOGY: This cross-sectional study was conducted at Dr Ruth KM Pfau CHK from July to August 2023. Newly diagnosed pulmonary tuberculosis cases of either gender, between 14-40...

Objectives To assess medical students’ perceptions regarding learning, teachers, academics, atmosphere at campus and social self-perceptions at Dow University of Health Sciences using Dundee Ready Education Environment Measure (DREEM) Inventory. Method This cross-sectional observational study was conducted from March 1st, 2022 to September 30th, 2...

Objectives To compare efficacy of 10-mg of vonoprazan daily & on alternate days by Gastroesophageal Reflux Disease Symptom Assessment Scale (GSAS) Method This prospective interventional cohort was done at Department of Medicine/Gastroenterology Dow Medical College, Karachi, Pakistan during the period August 2022 & January 2023. Potential participa...

Objective To compare the healing of post-cesarean infected wounds by a combination of honey and povidone iodine & povidone-iodine alone dressings using ASEPSIS Score. Method This prospective randomised cohort study was carried out at at OBGYN Department Jinnah Postgraduate Medical Center from 1st August 2022 till 31st December 2022. Patients were...

Objective: To determine correlation of HbA1c with serum iron and transferrin saturation in non-diabetic patients with iron deficiency. Methods: This cross-sectional comparative study was conducted at Dr Ruth KM Pfau Civil Hospital Karachi from 15th September 2021 to 14th March 2022, on non-diabetic patients based on fasting blood sugar (FBS) of...

Objective: To determine the effect of Remdesivir on liver enzymes and renal functions in SARS-CoV-2 patients. Methods: This prospective cohort study was conducted at Dr. Ruth KM Pfau, Civil Hospital Karachi between 1st December 2021 to 31st January, 2022. All patients of severe SARS-CoV-2 infection who received Inj. Remdesivir for five days as p...

Objective: To present and validate psychometric properties of Urdu version CLDQ, yet another objective was to do exploratory factorial analysis (EFA) of CLDQ Urdu version. Methods: This Cross-sectional Analytical Study was conducted at Dr. Ruth K.M. Pfau Civil Hospital Karachi during the period Nov. 15, 2021 to Jan. 30, 2022. CLDQ Urdu questionn...

Objective: To describe the clinical, etiological and neuroimaging profile of children with microcephaly at a tertiary care children hospital of Karachi Study Design: Cross sectional study Place and Duration of Study: The study was conducted at neurology outpatient department of National institute of child health (NICH) Karachi from 1st December 202...

Objectives: To determine the frequency of vaccination status in patients with SARS-CoV-2 infection. Methods: This case-control study was conducted at Dr Ruth KM Pfau Civil Hospital Karachi, Pakistan between September 2021 to October 2021. All patients who had positive PCR on nasopharyngeal swab for SARS-CoV-2 infection were included. Information...

Objectives: To determine the frequency of caesarean section with its indication by grouping according to Modified Robson's Criteria at JPMC. Methods: This is a retrospective study done from 1st January to 30th June 2018. Records of all Caesarean Section performed during the study period were retrieved from elective and emergency operation theatr...

Background: Estimating correct gestational age is the first and foremost goal of obstetrician and gynaecologist and cannot be underestimated. Commonly the parameters used are BPD, head circumference (HC), Femur length (FL), Abdominal circumference (AC). Recently transverse cerebellar diameter is a new diagnostic tool to measure the gestational age....

Objectives: To assess frailty in cirrhotic by calculating Liver Frailty Index (LFI) using bedside clinical tests and correlate it with Child-Turcotte-Pugh (CTP), MELD, MELD Na, Fib- 4 and Transient Elastography (TE) scores. Methods: This cross-sectional observational comparative study was carried out in Dr Ruth KM Pfau Civil Hospital, Karachi fr...

Objectives: To compare the efficacy of Vonoprazan based dual treatment versus PPI based treatment for the eradication of Helicobacter pylori infection. Methods: A randomized controlled trial was conducted in Department of Medicine/Gastroenterology Ruth KM Pfau Civil Hospital, DMC during the period of 22 June to 21 September 2021. Sample size was...

Introduction: Gastro-esophageal reflux disease (GERD) is a common gastrointestinal disorder that occurs when backflow of the gastric contents into the esophagus results in troublesome symptoms. Though GERD has been extensively studied in Western populations, literature on the management of GERD in patients in Africa and Middle East (AME) is scarce...

Objectives: This study aimed to validate Baveno-VI recommendations for variceal screening in cACLD in our region and proposed our own cutoff values. Methods: Prospective cross-sectional study was conducted on cACLD patients from August 2020 till April 2021. Patients segregated into Group-A, having Liver stiffness measurement (LSM) of ≥ 20 kPa an...

Objectives This study was conducted to determine impact of insulin resistance using Homeostatic Model Assessment of Insulin Resistance (HOMA‐IR) score and BMI in non‐hypoxemic out‐patients with COPD on FEV1 using linear and polynomial regressions and to determine their correlation. Methods COPD patients of both genders were included after informed...

Objective: To determine frequency of Muscle Weakness in Non-Hypoxemic COPD out-patients and Comparison with age matched non-COPD Controls. Methods: This cross-sectional study was conducted at OPD of Ojha Institute of Chest Diseases and Medicine, Dow University of Health Sciences, Karachi, Pakistan, during the period 8th September 2019 till 30th...

Objective: To compare 7-Day All-Cause Mortality among HDU Patients with Modified Early Warning Score of ≥5 with Those with Score of <5. Methods: All patients of age more than 18 years, of either gender admitted in HDU of Medical Unit-II, CHK between September 2019 to February 2020 were included. MEWS was calculated for each patient at time of ad...

Objective: To determine the frequency of hyponatremia in patients taking Sodium Picosulfate Solution (SPS) solution for bowel preparation prior to colonoscopy and to compare serum sodium levels before and after SPS. Methods: This interventional study was conducted at Dr. Ruth K. M. Pfau, Civil Hospital Karachi between June 2019 to November 2019....

Objective: To estimate frequency of silent carotid artery stenosis and its associated factors in diabetic patients attending a tertiary care hospital. Methods: This cross-sectional study was conducted in tertiary care Civil Hospital, Karachi from March 2019 to September 2019,. A total of 166 patients with Diabetes Mellitus were included in this...

Approximately one half of patients develop ascites within 10 years of diagnosis of compensated cirrhosis. It is a poor prognostic indicator, with only 50% surviving beyond two years. Mortality worsens significantly to 20% to 50% at one year if the ascites becomes refractory to medical therapy. Pakistan has one of the highest prevalence of viral hep...

Objective: To determine correlation between transient elastography values with serum ferritin and duration of infection in patients of hepatitis C. Methods: A cross-sectional study was conducted at medical units of Civil Hospital, Karachi. The study protocol was approved by the Research Evaluation Unit of College of Physician and Surgeon Pakista...

Objective: To determine number of sessions of Endoscopic variceal band ligation required to obliterate the esophageal varices. Methods: This study was conducted at Civil Hospital Karachi between June 2018 to April 2019. All patients undergoing endoscopic Variceal Band Ligation (EVBL) were inducted. Number of sessions of band ligation required to...

Objective: To determine effect of pre-endoscopy intake of simethicone solution on endoscopic mucosal visibility. Methodology: A randomized, single blinded placebo control trial was done in patients undergoing oesophago-gastro-duodenoscopy for any indication at DOTs Endoscopy Suite, CHK during the period of April to June 2019. Informed consent wa...

Objective: To determine number of sessions of Endoscopic variceal band ligation required to obliterate the esophageal varices. Methods: This study was conducted at Civil Hospital Karachi between June 2018 to April 2019. All patients undergoing endoscopic Variceal Band Ligation (EVBL) were inducted. Number of sessions of band ligation required to ob...

Objective: To determine the caecal intubation time depending on bowel preparation as per Boston Bowel Preparation Scale. Methods: This cross-sectional study was conducted at Dr. Ruth K. M. Pfau, Civil Hospital Karachi between August 2018 to February 2019. A total of 201 patients were included in the study. Time was recorded from insertion of col...

Objectives To document frequency of non-specific impairment of lung functions (NILF) in patients of HCV and to compare according to gender, genotype, liver fibrosis score and smoking status. Methods Patients of chronic hepatitis C were included after informed consent. Demographic data was recorded, and they underwent baseline investigations, fibro...

Objective To determine the frequency of mycobacterium tuberculosis detection, in bronchial washing in sputum-scarce cases of suspected pulmonary tuberculosis. Methods A descriptive cross-sectional study was conducted at the Ojha Institute of Chest Diseases, Dow University of Health Sciences, Karachi, during July 2016 to December 2017. Sputum-scarc...

Objective To determine level and factors of job satisfaction among doctors working in tertiary care hospitals in Pakistan. Methods This is a multi-center cross-sectional survey conducted among Post graduate trainees, medical officers, consultants and faculty doctors. Job satisfaction was measured using 35 specific questions about sources of work-r...

Objective: To determine the frequency of mycobacterium tuberculosis detection, in bronchial washing in sputum-scarce cases of suspected pulmonary tuberculosis. Methods: A descriptive cross-sectional study was conducted at the Ojha Institute of Chest Diseases, Dow University of Health Sciences, Karachi, during July 2016 to December 2017. Sputum-scar...

Treating hepatitis C has never been so convenient after the advent of Directly Acting Antivirals (DAA). Convenience is at both ends; for the doctors to prescribe and for patients to comply due to all oral therapy with few adverse effects. Many are already in market, these include, Sofosbuvir, Declastavir & Velpastavir while many others are in pipel...

Objective: To determine diagnostic yield of Closed Pleural Biopsy (CPB) and Cytology in Exudative Pleural Effusion (PE). Methods: This prospective comparative study was conducted at Chest Unit-II & Medical Unit-IV of Dow University of Health Sciences, Karachi Pakistan from January 2011 till December 2014. Results: Ninety-four patients with exudativ...

In Pakistan, we have 4.9% prevalence of HCV in general population, with 79% genotype 3. Recently Sofosbuvir has been made available at compassionate price in Pakistan. Management of chronic hepatitis C includes counseling of HCV patients, their proper assessment to select those who need antiviral therapy, initiation of appropriate antiviral agents...

Objective: To compare mean homeostatic model assessment of insulin resistance (HOMA-IR) in patients with and without chronic obstructive pulmonary disease (COPD). Methods: A Case control analytic study was conducted in medical outpatient department of Medial Unit-II of Dow University of Health Sciences from April 2013 to September 2013. All pati...

Pakistan has the highest number of individuals with active hepatitis C virus (HCV) infection of all countries except China, but unlike China, the total number of infections in Pakistan is not declining. An estimated 4.2% of the general population or 7,192, 900 persons were infected with HCV in 2014. Therefore, it is critical to assess the impact of...

The hepatitis C virus (HCV) epidemic was forecasted through 2030 for 15 countries in Europe, the Middle East and Asia, and the relative impact of two scenarios was considered: increased treatment efficacy while holding the annual number of treated patients constant and increased treatment efficacy and an increased annual number of treated patients....

Detailed, country-specific epidemiological data are needed to characterize the burden of chronic hepatitis C virus (HCV) infection around the world. With new treatment options available, policy makers and public health officials must reconsider national strategies for infection control. In this study of 15 countries, published and unpublished data...

The total number, morbidity and mortality attributed to viraemic hepatitis C virus (HCV) infections change over time making it difficult to compare reported estimates from different years. Models were developed for 15 countries to quantify and characterize the viraemic population and forecast the changes in the infected population and the correspon...

Gastroesophageal reflux disease (GERD) is the most common acid-related disorder encountered during clinical practice in Pakistan and is associated with significant impairment of health-related quality of life. A number of guidelines and recommendations for the diagnosis and management of GERD have been published in different countries, but a Pakist...

Objective: To compare the efficacy of British Thoracic Society and American Thoracic Society guidelines for reintroduction of anti-tuberculous therapy after drug-induced liver injury, and to assess the ease of administration of each guideline on a scale of 1-10. Methods: The randomised prospective interventional study was conducted at the Depart...

BACKGROUND: Prevalence of hair fall and its relationship with stress has not been studied in Pakistan. Our study attempts at determining the prevalence of hair fall among female medical students of Dow Medical College, Karachi and to examine the relationship between stress and hair fall. METHODS: A cross-sectional study was conducted. All female m...

Objective: To determine insulin resistance in non-diabetic chronic hepatitis C patients using Homeostatic Model Assessment of Insulin Resistance (HOMA-IR). Methodology: Patients having anti-HCV positive were included in this study. Patients with diabetes mellitus, thyroid disease, hyperlipidemias, hypercortisolism and infective diseases other than...

Objectives: To determine frequency of depression in chronic hepatitis C naïve patients before interferon therapy using CES-D questionnaire. Methodology: Patients testing positive antibodies to HCV by EIA of more than 6 months duration and who have not taken interferon therapy previously were included after taking informed consent. Patients who had...

The aim of this study was to identify the risk factors for perinatal deaths in Pakistan, where perinatal mortality is still very high. This prospective cohort study was conducted in Sindh Government Lyari General Hospital, Karachi from 1 May 2006 to 30 April 2008. During this period, all perinatal deaths and each live infant delivered following eve...

Objective: To determine the frequency of Eosinophilic Esophagitis (EoE) in patients undergoing upper GI endoscopy. Methodology: Patients undergoing upper GI endoscopy for any indication were subjected to additional esophageal biopsies for dermination of eosinophilic esophagitis. The additional biopsy protocol was two each from proximal esophagus, d...

Objective: To determine the frequency of colonization of intravenous (IV) cannula by microorganism in patients admitted to intensive care unit (ICU) and to determine the frequency of common organisms involved in colonization of IV-cannula. Methodology: A total of 369 patients of age more than 12 years, and meeting inclusion criteria of the study we...

Objective: To determine the information about myths regarding asthma among internet users. Methodology: An open access internet based close ended survey was hosted on a website which included questions related to common myths regarding asthma. Data was entered automatically into a database at the hosting servers. The survey invitations were sent by...

Objective: To determine the frequency of colonization of intravenous (IV) cannula by microorganism in patients admitted to intensive care unit (ICU) and to determine the frequency of common organisms involved in colonization of IV-cannula. Methodology: A total of 369 patients of age more than 12 years, and meeting inclusion criteria of the study we...

Objectives: To determine the BMI status of the students of Dow Medical College and to calculate frequency of different BMI categories. Methodology: A cross-sectional questionnaire based study was carried out in Dow Medical College, Dow University of Health Sciences, Karachi. Body weight and height were measured and body mass index (BMI) values were...

Objective: To determine the frequency of acute HCV infection after needle stick injury and its treatment outcome. Methodology: Patients with HCV positive needle stick injury and reporting within 72 hours of incident were selected. Co-infections with HBV, HDV, HIV, hematological disorders and depression were excluded. Anti-HCV was done at presentati...

To determine the correlation of Adjusted Blood Requirement Index (ABRI) with the 7th day outcome in patients presenting with acute variceal bleeding. All patients presenting with acute variceal hemorrhage (AVH) were included. Patients with previous band ligation, sclerotherapy, gastrointestinal or hepatic malignancies were excluded. Patients were m...

OBJECTIVE: To document frequency of Hepatitis B and C in patients undergoing elective surgery. DESIGN: Descriptive case series SETTING: Surgical Unit II Civil Hospital Karachi, from June 2005 to May 2006. METHODS: All patients undergoing elective surgery were screened for Hepatitis B and C by enzyme immunoassay (EIA). Risk factors for hepatitis B a...

Objective: To detect neuropathy in diabetics who are clinically asymptomatic, using SW monofilament and to correlate the frequency of detected neuropathy with the duration of diabetes. Methodology: Known patients of type 2 diabetes that do not have symptoms of peripheral neuropathy were included. Height, weight and duration of diabetes were measure...

To determine the frequency of hepatitis C and D in patients of chronic hepatitis B and the treatment response of hepatitis B in such patients. Case series. Civil Hospital and Lyari General Hospital, Dow University of Health Sciences, from July 2003 to June 2005. All patients of hepatitis B presenting during the study period were screened for triple...

To document the sustained virological response (SVR) in rapid virological responders (RVR) of genotype-3 chronic hepatitis C with standard interferon (SdIF). Hepatitis C genotype-3 patients during the period July 2006 and June 2007 were included. Complete blood counts, prothrombin time, ALT, albumin, qualitative HCV RNA were done. SdIF and ribaviri...

Large platelets are more thrombogenic and thus put the patient at a higher risk status. Mean platelet volume (MPV) is a determinant of platelet functionality and increased MPV is associated with increased risk for myocardial infarction, stroke and transient ischaemic attacks. The objective of this study is to compare the MPV in patients with diabet...

Hepatitis B and hepatitis C are global health care problems causing morbidity and mortality. Much of it could be prevented by better education of the masses regarding its spread. The study was conducted to assess the knowledge base of internet users of Pakistan to help in formulating education strategies. A survey questionnaire consisting of 20 clo...

Objective: To determine the frequency of dual infection of Tuberculosis and Human Immunodeficiency Virus (HIV) and document the sexual practices of infected patients. Design: Cross-sectional study. Place and duration of study: Medical Unit-IV of Civil Hospital, Karachi, Pakistan, in collaboration with Sindh AIDS Control Program at Services Hos...

Objective: To compare hemoglobin, ferritin, and vitamin B12 levels in patients undergoing upper GI endoscopy according to their Helicobacter pylori status. Study design: Cross-sectional study. Place and Duration of the Study: Civil Hospital and Lyari General Hospitals, Karachi, from March 2004 to June 2006. Patients and methods: All patients u...

Objective: To compare hemoglobin, ferritin, and vitamin B12 levels in patients undergoing upper Gl endoscopy according to their Helicobacter pylori Status. Study Design: Cross-sectional study. Place and Duration of the Study: Civil Hospital and Lyari General Hospitals, Karachi, from March 2004 to June 2006. Patients and Methods: All patients underg...

To determine HBV suppression in patients with dual HBV and HDV infection after 48 weeks with 10.0 MIU of interferon-a 2b. Quasi experimental study. Civil Hospital, Karachi and Lyari General Hospital, Karachi, from July 2003 to June 2005. All HBsAg positive patients were screened for anti-HDV, all positives were included. Baseline investigations, li...

Autoimmune hepatitis is an uncommon cause o f chronic hepatitis in Pakistan. One such case is describedoccurring in an adult female cirrhotic diagnosed on raised serum IgG and LKM-I.

Quality of Life has an important status in patient management suffering from chronic disease like cirrhosis and health related quality of life has significant impact on patient management. This study was conducted to evaluate the correlation of health related quality of life with disease severity in patients of cirrhosis of liver. This cross-sectio...

To compare QTc duration and Heart Rate (HR) in patients with cirrhosis with non-cirrhotic controls. Cross-sectional analytical study. Civil Hospital and Lyari General Hospital, Karachi, from March 2004 to February 2006. Confirmed patients of cirrhosis were selected and allocated to Group-I. An equal number of non-cirrhotic patients were taken as co...

Objective: To determine the correlation of ABRI with treatment intervention and outcome as discharged or expired in patients of acute variceal bleed. Design: Cross-sectional study Patients and Methods: Records of all die patients admitted in Medical IJnit-IV, Civil Hospital Karachi with acute variceal bleeding during January 2004 to October 20...

Hepatitis D has been shown to be reducing in frequency in the Western countries commensurate with HBV decline while recent reports from Pakistan are indicating a rising frequency. This review describes the management and prevention of this often overlooked cause of hepatitis.

To find the frequency of hepatitis 'D' in patients of hepatitis 'B' seeking treatment and to compare clinical and biochemical features in patients harboring HDV with those who are not. Cross-sectional study. Medical Unit-IV, Civil Hospital Karachi, Medical Unit-VI and Surgical Unit-VII, Lyari General Hospital, Dow University of Health Sciences, Kar...

To determine the correlation between the clinical, endoscopic and histological findings in patients of GERD. An observational, cross-sectional study. Lyari General Hospital, Dow University of Health Sciences from November 2003 to October 2004. Patients complaining of heartburn and/or acid regurgitation at least twice per week for at least 3 months...

This case report describes a young female with idiopathic gastroparesis, who presented with persistent vomiting and weight loss. Treatment with erythromycin and tegaserod led to the recovery from symptoms and weight gain.

To study the frequency of Helicobacter pylori antibodies in patients presenting with porto-systemic encephalopathy due to liver disease. An observational, cross-sectional study. Different medical units at Civil Hospital, Karachi between May 2001 and April 2002. During the study period, seventy-six patients of porto-systemic encephalopathy due to li...

To evaluate the baseline National Institute of Health Stroke Scale (NIHSS) score as a predictor of functional outcome after ischemic stroke. A cross-sectional study. The study was carried out between September 2001 and May 2002 at the Department of Medicine, Civil Hospital, Karachi. The study included 50 patients who presented to Civil Hospital, Ka...

To record the effect of pyrazinamide on uric acid in patients of tuberculosis. Descriptive and observational study. Chandka Medical College Hospital, Larkana from February 2000 to January 2003. All patients receiving anti-tuberculosis drugs with pyrazinamide were included. Serum uric acid levels were monitored at weeks 0, 2, 8 and 12 of therapy. Se...

To document the frequency of rectal varices in patients with cirrhosis of liver and compare it with that of oesophageal varices in liver and to compare the frequency of rectal varices with non-cirrhotic controls. A cross-sectional analytical survey. The study was conducted in the medical wards of Civil Hospital, Karachi from August 2000 to July 200...

Objective: To see the efficacy of octreotide and sclerotherapy and combination thereof in control of variceal bleeding. Design: A prospective, open-label randomised study. Place and Duration of Study: Department of Medicine, Chandka Medical College, Larkana and Lateef Medical Complex, Larkana, Pakistan. Patients and Methods: This study was conducte...

Objective: To see the efficacy of octreotide and sclerotherapy and combination thereof in control of variceal bleeding. Design: A prospective, open-label randomised study. Place and Duration of Study: Department of Medicine, Chandka Medical College, Larkana and Lateef Medical Complex, Larkana, Pakistan. Patients and Methods: This study was conducte...

Objective: Chronic hepatitis due to C virus may regress with Interferon-alpha-2b (INF) therapy. Forty percent cases have an initial response to this therapy, but most relapse after stopping therapy. Because of this limited response, alternative forms of therapy including combining interferon with other antiviral agents have been investigated. Hence...

Objectives: Systemic lupus erythematosus (SLE), a multisystem disease thought to be an uncommon disease in our country was studied to see and compare its presentation and clinical features at Karachi and Larkana. Design: A cross-sectional and observational study. Place and Duration of Study: It was conducted at Karachi and Larkana during the period...

Objective: To evaluate safety, morbidity and complication of intracorporeal cystolithotripsy in children. Design: It was a prospective study. Place and Duration of Study: The study was conducted from February, 1998 to January, 2000 at Almas Kidney and Lithotripsy Centre, Larkana. Patients/Methods: In all 50 children with single or multiple vesical...

Mean maximum anal resting pressure is directly related to the activity of the smooth muscles of the internal and external sphincters and has been found to be increased in the patients of anal fissure. It has been shown that blood flow at the posterior midline of anoderm is inversely related to the mean maximum anal resting pressure, and topical app...

Efficacy of endoscopic variceal sclerotherapy (EVS) alone and in combination with octreotide in controlling acute variceal bleeding and preventing early rebleeding was compared in a double-blind study. Consecutive patients presenting with variceal bleeding with low-risk liver cirrhosis were randomized into two groups. Group A received EVS with 3-5...

Background— A young medical student developed severe toxicity, including seizures, respiratory distress, hypotension, and asystole, and died after gargling with lidocaine before upper gastrointestinal endoscopy. Upper gastrointestinal endoscopy is usually a safe outpatient procedure before which the throat is often anaesthetised. Case report— A 21...

Objective: To evaluate safety, morbidity and complication of intracorporeal cystolithotripsy in children. Design: It was a prospective study. Place and Duration of Study: The study was conducted from February, 1998 to January, 2000 at Almas Kidney and Lithotripsy Centre, Larkana. Patients/Methods: In all 50 children with single or multiple vesical...

A retrospective study of 228 cases of malignant skin tumors, reported at Chandka Medical College Hospital (CMCH), Larkana, and Larkana Institute of Nuclear Medicine and Radiotherapy (LINAR), during the period of 8 years from January, 1991 to December, 1998 is presented. During this period, maximum number of cases were reported in 1994. Out of 228 c...

Objectives: Systemic lupus erythematosus (SLE), a multisystem disease thought to be an uncommon disease ir, our country was studied to see and compare its presentation and clinical features at Karachi and Larkana. Design: A cross-sectional and observational study. Place and Duration of Study: It was conducted at Karachi and Larkana during the perio...

Efficacy of low-dose, intra-dermal hepatitis B vaccination was assessed among sixty-one doctors and paramedical staff of Chandka Medical College Hospital, Larkana. Subjects were randomly divided into two groups. Group-A (n = 25) received 20 micrograms of purified Hepatitis B Surface Antigen (Euvax B, LG Chemicals) by i.m. injection in the deltoid b...

Seven hundred sixty one patients of iridocyclitis confirmed after slit-lamp examination were inducted into the study. Selected patients were thoroughly examined and investigated for the presence of any underlying systemic disease. One hundred fourteen (14.98%) patients were found to have some underlying systemic disease. Rheumatoid arthritis was pr...

Cirhotic patients with ascites presenting at Chandka Medical College Hospital, Larkana, from May 1997 to June 1998 were included in the study to see the frequency, bacterial spectrum, clinical and biochemical features of spontaneous bacterial peritonitis (SBP). Ninety cases (63 males and 27 females) of liver cirrhosis with ascites were selected for...

Fifty-six patients of confirmed myocardial infarction were inducted into the study. Healthy attendants of patients donating blood to their relatives were-taken as control. Weight, height, smoking habits and diabetic status were recorded. Base line laboratory investigations, lipid profiles, creatine kinase total and MB, Troponin T and IgG antibodies...

This study was conducted to determine the prevalence of microalbuminuria and macroalbuminuria in insulin dependent diabetes mellitus (IDDM) and non insulin dependent diabetes mellitus (NIDDM) patients and their relationship with some known chronic complications of diabetes. Four hundred sixty two patients attending the diabetic clinic, Chandka Medi...