B. Ayres

B. Ayres
St George's, University of London | SGUL · Medical School

About

135
Publications
6,623
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398
Citations
Citations since 2017
49 Research Items
279 Citations
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20172018201920202021202220230204060
20172018201920202021202220230204060

Publications

Publications (135)
Article
Full-text available
Objectives To develop a nomogram that could predict spontaneous stone passage (SSP) in patients presenting with acute ureteric colic who are suitable for conservative management. Patients and Methods A 2517 patient dataset was utilised from an international multicentre cohort study (MIMIC, A Multi-centre Cohort Study Evaluating the role of Inflamma...
Article
Full-text available
Objectives: Following tumour positive sentinel lymph node biopsy (+DSNB), completion inguinal lymph node dissection (ILND) is negative in 84-89% of basins. Thus, ILND after +DSNB may be considered overtreatment resulting in substantial morbidity. This study aimed to develop a predictive model for additional inguinal lymph node metastases (LNM) at...
Article
Full-text available
Reconstruction after excision of locoregionally recurrent penile cancer can be a surgical challenge. In this short paper, we present two cases of perineal reconstruction using bilateral gracilis flaps supplemented by abdominal advancement for salvage of recurrent penile cancer, reviewing relevant literature and outlining our local approach to the p...
Article
Full-text available
Perivascular epithelioid cell neoplasms represent a group of uncommon mesenchymal tumours with as yet undiscovered benign counterpart. Although perivascular epithelioid cell neoplasms have been described arising in most organ systems as well as in soft tissue and bone, only a small number of perivascular epithelioid cell neoplasms have been reporte...
Article
Full-text available
PurposeRed cell distribution width (RDW) measures red cells’ size variability. Metastatic penile cancer displays poor chemotherapy response. As no validated prognostic predictor exists, we investigated whether RDW correlates independently with survival outcomes in metastatic penile cancer treated by chemotherapy.Methods Electronic chemotherapy file...
Article
Introduction: The standard intravesical treatment for high risk non muscle invasive bladder cancer (HRNMIBC) is Bacillus Calmette-Guérin (BCG), with failure often resulting in cystectomy. Radiofrequency-Induced Thermo-chemotherapeutic Effect Mitomycin (RITE-MMC) can be an alternative in BCG failure. There has been concern that RITE-MMC may delay a...
Article
Objectives: To assess the relationship of white blood cell count (WBC) and other routinely collected inflammatory and clinical markers including stone size, stone position, and medical expulsive therapy use (MET), with spontaneous stone passage (SSP) in a large contemporary cohort of patients with acute ureteric colic, as there are conflicting data...
Article
Full-text available
Objective To examine the effect of intravesical radiofrequency-induced chemohyperthermia (RF-CHT) in carcinoma in-situ (CIS) patients overall and split according to previously received therapy. Methods CIS patients that underwent an induction and maintenance phase of≥6 RF-CHT instillations, and had either pathology or cystoscopy plus cytology avai...
Article
Background Organ sparing surgery (OSS) in the treatment of penile squamous cell cancer (SCCp) is well established. A 5 mm margin has previously been considered oncologically safe. Objective To evaluate the significance of close surgical margins in OSS and clinico‐pathological factors that may influence local recurrence. Patients and Methods At ou...
Article
Full-text available
Introduction & Objectives There is conflicting evidence on the role of medical expulsive therapy (MET) in spontaneous stone passage in patients with acute ureteric colic. Randomised trial data has not shown a role for MET use, though these have been underpowered to explore its role in specific patient subgroups. It is unknown whether MET use may h...
Conference Paper
1 Eastbourne District General Hospital: East Sussex Healthcare Nhs Trust, Eastbourne, United Kingdom 2 Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom 3 St George's University Hospitals NHS Foundation Trust, London, United Kingdom 4 Brighton and Sussex University Hospitals NHS Trust , Brighton, United Kingdom 5 University Hospital...
Article
Objective Penile cancer services were centralised in England in 2002. Has this had an impact on treatments for penile cancer and survival? Patients and methods All cases of penile cancer from 1990 to 2009 were identified from national cancer registry data. Mortality data were obtained from the Office for National Statistics and survival data were...
Article
Achieving the best possible practice in the management of patients with penile cancer is hampered by a lack of evidence owing to the rare occurrence of this disease. New population-based data from the USA show improved surgical and medical practice patterns but also highlight challenges in providing optimum care to all patients.
Article
Full-text available
Sentinel lymph node biopsy (SLNB) is now an established technique in penile and pelvic cancers, resulting in a lower mortality and morbidity when compared with the traditional lymph node dissection. In renal cancer however, despite some early successes for the SLNB technique, paucity of data remains a problem, thus lymph node dissection and extende...
Article
Full-text available
To investigate and compare the trends in incidence and mortality of penile cancer between Australia, England and Wales, and the US, and provide hypotheses for these trends. Cancer registry data from 1982 to 2005 inclusive were obtained from Australia, England and Wales, and the United States. From these data, age-specific, -standardised and mortali...
Article
Hyperthermic mitomycin (HM) is a novel treatment modality for selected patients with high-risk non-muscle invasive bladder cancer (NMIBC). We sought to determine predictors of response to this therapy. A longitudinal, cohort study of 97 patients with high-risk NMIBC treated with ≥4 HM instillations on a prophylactic schedule was conducted. The prim...
Article
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Calcific uremic arteriolopathy or calciphylaxis is a rare condition that can present with clinical features similar to penile cancer. It is a diagnosis to consider in patients with end-stage renal failure (ESRF) presenting with a penile lesion. We describe one such case, where a patient with ESRF presented with a solid, tender penile mass and under...
Article
Glans resurfacing is a recently described technique in the management of precancerous lesions and superficial invasive tumours of the glans penis as well as cases of indolent persistent lichen sclerosus. The technique is complex and is usually only practiced in specialist centres with combined urological and plastic surgical expertise. Cosmetic and...
Article
Aim The aim of this study was to determine the added value of robotic surgery for radical cystectomy in the context of an established enhanced recovery programme (ERP). Background We have previously reported on ERP in open radical cystectomy (ORC) and shown that it is safe and not associated with an increase in complications or readmissions. Furth...
Article
Full-text available
We present a 21-year-old HIV-negative Somalian male who was diagnosed with an immunohistochemically proven human herpes virus 8 (HHV8)-positive primary penile Karposi's Sarcoma (KS). He was treated with local surgery and remained in complete clinical remission for 18 months. This is the first case of a heterosexual teenage and young adult (TYA) pat...
Article
Purpose of review: Prostate cancer remains the commonest nondermatological cause of cancer in Western men and the second leading cause of cancer death in these men. While low and intermediate-risk prostate cancers make up the vast bulk of prostate cancer diagnoses, it is high-risk prostate cancer that is a much larger killer. Management paradigms...
Article
The implementation of enhanced recovery programmes (ERPs) in colorectal surgery has seen improvements in the length of inpatient stay with no increase in complications. We investigated the role of ERP in radical cystectomy at our institution. Prospective data were collected from 26 consecutive patients prior to the introduction of the ERP and 51 pa...
Chapter
Holmium laser enucleation of the prostate Holmium laser enucleation of the prostate Holmium cystolitholapaxy Transurethral resection of prostate 1 Transurethral resection of prostate 2 Transurethral vaporisation of the prostate Use of catheter introducer An Alternative way to pass a urethral catheter post transurethral resection of prostate The 17F...
Article
Benjamin Ayres discusses the use of BCG in the management of non-muscle-invasive bladder cancer, emphasising the importance of controlling the inevitable side-effects of this toxic treatment. Copyright © 2013 John Wiley & Sons
Article
Full-text available
The principal advantage of dynamic sentinel lymph node biopsy (DSNB) over modified inguinal node dissection is the lower complication rate. The aim of this study was to identify factors associated with short-term complications of DSNB in order to lower morbidity of the procedure. Retrospective and prospective cohort studies were performed on patien...
Article
To evaluate the role of transperineal template prostate biopsies in men on active surveillance. In all, 101 men on active surveillance for prostate cancer underwent restaging transperineal template prostate biopsies at a single centre. Criteria for active surveillance were ≤75 years, Gleason ≤3+3, prostate-specific antigen (PSA) ≤15 ng/mL, clinical...