Azizallah Dehghan

Fasa University of Medical Sciences · Social Medicine

Background Chronic kidney disease (CKD) is associated with increased cardiovascular disease (CVD) risk factors and morbidity in the elderly population. This study aimed to examine the association between CKD and CVD risk factors in the elderly population of Fasa and Yazd (Shahdieh), Iran, using the data from the enrolment phase of Fasa and Shahedie...

Background Globorisk is one of the prediction tools for 10-year risk assessment of cardiovascular disease, featuring an office-based (non-laboratory-based) version. This version does not require laboratory tests for determining the CVD risk. The present study aims to determine the 10-year CVD risk using the office-based Globorisk model and factors...

Background Regarding the prevalence and pervasiveness of psychiatric disorders, which significantly affect not only the patients themselves, but also their families, family therapy has emerged as a promising intervention. This research examined the effects of Acceptance and Commitment Therapy (ACT) on stigma and family functioning in family members...

Background Imbalanced datasets pose significant challenges in predictive modeling, leading to biased outcomes and reduced model reliability. This study addresses data imbalance in diabetes prediction using machine learning techniques. Utilizing data from the Fasa Adult Cohort Study (FACS) with a 5-year follow-up of 10,000 participants, we developed...

Background Type 2 diabetes being a chronic condition that requires long-term care. This study examined the impact of an educational program using King’s goal attainment model on health behaviors and life satisfaction in type 2 diabetes patients. Methods This is a randomized controlled clinical trial with no blinding in which we tested two groups o...

Background The worldwide prevalence of type 2 diabetes mellitus in adults is experiencing a rapid increase. This study aimed to identify the factors affecting the survival of prediabetic patients using a comparison of the Cox proportional hazards model (CPH) and the Random survival forest (RSF). Method This prospective cohort study was performed o...

Background Androgenic alopecia (AGA), the most prevalent hair loss type, causes major psychological distress and reduced quality of life. A definite and safe cure/prevention for this condition is still lacking. The role of oxidative stress and inflammation in AGA pathogenesis prompted us to investigate the association between dietary antioxidant in...

Hypertension is a very common comorbidity in type 2 diabetes patients, which leads to important health and treatment challenges. The present study was conducted with the aim of determining the prevalence of hypertension and its risk factors in type 2 diabetes patients. This study was conducted using cross-sectional data from 1245 participants aged...

Background Belonging to the clinical environment and the professional values of the performers play a role in forming a professional identity. Therefore, it is necessary to understand the degree of connection among these concepts. Aim This study aimed to examine the mediating effects of professional values on the relationship between nurses’ clini...

Background Metabolic syndrome (MetS) is a collection of medical conditions that elevate the chance of cardiovascular disease. An unhealthy diet is a major risk factors for MetS through different mechanisms, especially systemic chronic inflammation. Objective This study aimed to investigate the effect of dietary inflammatory potential on MetS incid...

Background Imbalanced datasets pose significant challenges in predictive modeling, leading to biased outcomes and reduced model reliability. This study addresses data imbalance in diabetes prediction using machine learning techniques. Utilizing data from the Fasa Adult Cohort Study (FACS) with a 5-year follow-up of 10,000 participants, we developed...

Background Metabolic syndrome (MetS) is a cluster of risk factors and the Framingham risk score (FRS) is a useful metric for measuring the 10-year cardiovascular disease (CVD) risk of the population. The present study aimed to determine the 10-year risk of cardiovascular disease using the Framingham risk score in people with and without MetS in a l...

Exercise can have a wide range of health benefits, including improving blood lipid profiles. For women to achieve optimal cardiovascular health, it is vital to determine the effect of exercise on their health and whether different exercise intensities can affect their blood lipid profile. A systematic review and meta-analysis were conducted to exam...

The skin cancer (mostly of melanoma cells) rate has increased in recent years due to genetic and epigenetic reasons. The efficient treatment of skin cancer is an unmet requirement to achieve specific anticancer activity, reduction of the costs and side effects, and precluding resistance of cancer cells. Hence, employment of proper nanocarriers is p...

Introduction Complementary and alternative medicine (CAM) has gained popularity as a therapeutic approach outside conventional medicine for various medical conditions. This study aimed to assess the prevalence, patterns, and disclosure of CAM use among patients with thyroid diseases in Iran. Methods This descriptive-analytic cross-sectional study...

Background & Objectives: Dyslipidemia is a major public health issue worldwide characterized by changes in lipid index such as cholesterol, Low Density Lipoprotein (LDL), High Density Lipoprotein (HDL) and triglycerides (TG).This manuscript aimed to investigate the associated factors of dyslipidemia in Fasa Persian cohort study. Materials & Methods...

Background Framingham risk score (FRS) and Atherosclerotic Cardiovascular Disease risk score (ASCVDrs) are widely used tools developed based on the American population. This study aimed to compare the ASCVDrs and FRS in an Iranian population. Method The participants of the Fasa Adult Cohort Study and the patients of the cardiovascular database of...

Background: Urinary stones rank as the third most common disease of the genitourinary system, following urinary tract infections and prostate diseases. Their incidence is influenced by various demographic, environmental, and genetic factors. Objectives: This study aimed to explore the association between Body Mass Index (BMI), blood lipids, and kid...

Background Regular, detailed reporting on population health by underlying cause of death is fundamental for public health decision making. Cause-specific estimates of mortality and the subsequent effects on life expectancy worldwide are valuable metrics to gauge progress in reducing mortality rates. These estimates are particularly important follow...

Background Disorders affecting the nervous system are diverse and include neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment following COVID-19. Previous publications from the Global Burden of Disease, Injuries, and Risk Factor Study estimated the burden of 15 neurological conditio...

Background Acute myocardial infarction is still a leading cause of death worldwide, accounting for roughly three million deaths yearly. This study aimed to investigate the prevalence and factors associated with ST-Segment Elevation Myocardial Infarction and Non-ST Segment Elevation Myocardial Infarction in Iran. Methods This cross-sectional study...

Background Neck pain is a highly prevalent condition that leads to considerable pain, disability, and economic cost. We present the most current estimates of neck pain prevalence and years lived with disability (YLDs) from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) by age, sex, and location, with forecasted prevalence to...

Background One of the modifiable risk factors for cardiovascular diseases is the inter-arm blood pressure difference (IAD), which can be easily measured. This study aimed to determine the prevalence and factors related to the Iranian population’s inter-arm differences in systolic and diastolic blood pressure. Method This cross-sectional study was...

Objective Brucellosis is a highly contagious disease which is transmitted from animals to humans. One of the populations at high risk of infection is those living in rural areas. The present study was conducted to investigate rural populations’ knowledge, attitude, and practice about brucellosis in Iran. The study used a descriptive, cross-sectiona...

Background With increasing life expectancy and a growing population of older adults, the prevalence of osteoporosis has risen, resulting in a higher incidence of bone fractures, which necessitate extended treatment and specialized medical care. This study investigates the relationship between smoking, alcohol consumption, drug abuse, and osteoporos...

Burn injuries are considered an important public health problem in the world. Burns are considered the fourth most common kind of trauma in the world, after traffic accidents, falls, and interpersonal violence. Various biochemical agents are involved in the burn healing process such as cytokines (such as IL-6 and TNF-α), antioxidants, and liver and...

Background: Osteoporosis, as the most common bone-related disease, causes massive irrecoverable consequences for the health level and life quality of people, especially at advanced ages. The present research aimed to evaluate the prevalence and risk factors of osteoporosis and the correlation between drug consumption and osteoporosis. The present s...

Background Medication safety competence is very important as one of the clinical skills among nursing students to provide safe nursing care. The lack of medication safety competence in nursing students leads to occurrence of medication errors subsequently jeopardizing patient safety. Thus, the present study was conducted to investigate safe nursing...

Introduction: Due to the increase in public interest in the use of traditional and complementary medicine in various diseases, it is necessary in order to adopt a suitable policy that know the extent of people's use, the type of use and the characteristics of the people. We aimed to determine the frequency and pattern of complementary and alternati...

Background Addiction increases the risk of different lifelong disorders. However, there are limited studies evaluating the effects of opioid use disorder (OUD) on thyroid function. The present study aimed to compare the thyroid function of individuals with and without OUD. Methods This cross-sectional study was conducted on 700 eligible participan...

Background The study aimed to estimate the attributable burden to kidney dysfunction as a metabolic risk factor in the North Africa and Middle East (NAME) region and its 21 countries in 1990-2019. Methods The data used in this study were obtained from the Global Burden of Diseases (GBD) 2019 study, which provided estimated measures of deaths, disa...

Psychosocial interventions have shown potential in reducing the fear of re-injury after anterior cruciate ligament reconstruction (ACLR), but this has not been systematically reviewed. The aim of this study was to assess the available evidence on the effect of psychosocial interventions on kinesiophobia after ACLR. Two independent researchers condu...

Background: Metabolic syndrome (MS) is a cluster of metabolic abnormalities that dramatically causes Non-Alcoholic Fatty Liver disease (NAFLD). NAFLD is a common disorder that ranges from simple steatosis to lethal hepatocellular carcinoma. Therefore, preventing the development of MS to NAFLD is a worldwide priority. Interestingly recent studies sh...

Background: Two versions of Framingham's 10-year risk score are defined for cardiovascular diseases, namely laboratory-based and office-based models. The former is mainly employed in high-income countries, but unfortunately, it is not cost-effective or practical to utilize it in countries with poor facilities. Therefore, the present study aims to...

Background: Systemic lupus erythematosus (SLE) as an inflammatory autoimmune disease, originates from the production of autoantibodies against several cellular components, especially nuclear components such as DNA. Prolactin consists of 199 amino acids and due to the structural similarity with cytokines, this polypeptide has the ability to modulate...

The Globorisk and WHO cardiovascular risk prediction models are country-specific and region-specific, respectively. The goal of this study was to assess the agreement and correlation between the WHO and Globorisk 10-year cardiovascular disease risk prediction models. The baseline data of 6796 individuals aged 40–74 years who participated in the Fas...

Background: Childhood hypertension can have serious consequences for children, especially during their adulthood. This study aimed to determine the prevalence of hypertension and its related factors in children aged 7 to 12 years in Larestan (Iran). Methods: In this cross-sectional study, 1110 students from 7 to 12 years old in Larestan were enroll...

Background Non-alcoholic fatty liver disease (NAFLD) is a prevalent liver disease predisposing patients to life-threatening conditions, including cirrhosis. There is evidence that the incidence of NAFLD is related to the individuals’ dietary patterns; however, it is still remaining unknown whether the inflammatory potential of various foods/dietary...

Background: Oral mucositis (OM), an acute inflammation of the oral cavity, is a common complication in patients undergoing invasive myeloblastic chemotherapy or radiation therapy. 5-fluorouracil (5-FU) is one of the most effective therapeutic drugs, but one of the common side effects of 5-FU administration is OM. Unfortunately, no suitable treatme...

Background: Surgical site infection (SSI) and surgical wound dehiscence are among the main causes of readmission and an increase in treatment costs for patients undergoing cesarean section (CS) surgery. The present study aimed to investigate the prevalence and causes of SSI and surgical wound dehiscence after cesarean delivery in Zeinab hospital in...

Type 2 diabetes (T2DM) and its complications can cause severe morbidity and mortality. The researchers and clinicians’ attention has been toward finding an efficient treatment for T2DM to decrease its heavy burden on the people and countries. Whey protein (WP) is a known glucose-lowering treatment of traditional Persian medicine. This randomized co...

Background: The WHO model has laboratory-based and non-laboratory-based versions for 10-year risk prediction of cardiovascular diseases. Due to the fact that in some settings, there may not be the necessary facilities for risk assessment with a laboratory-based model, the present study aimed to determine the agreement between laboratory-based and...

The inter-arm blood pressure difference has been advocated to be associated with cardiovascular mortality and morbidity. Our study aimed to investigate the association between Inter-arm systolic and diastolic blood pressure differences and Cardio Vascular Disease (CVD). A total of 10,126 participants aged 35–70 years old were enrolled in a prospect...

Background Low back pain is highly prevalent and the main cause of years lived with disability (YLDs). We present the most up-to-date global, regional, and national data on prevalence and YLDs for low back pain from the Global Burden of Diseases, Injuries, and Risk Factors Study 2021. Methods Population-based studies from 1980 to 2019 identified i...

Background: Low back pain is highly prevalent and the main cause of years lived with disability (YLDs). We present the most up-to-date global, regional, and national data on prevalence and YLDs for low back pain from the Global Burden of Diseases, Injuries, and Risk Factors Study 2021. Methods: Population-based studies from 1980 to 2019 identified...

We used machine learning methods to investigate if body composition indices predict hypertension. Data from a cohort study was used, and 4663 records were included (2156 were male, 1099 with hypertension, with the age range of 35-70 years old). Body composition analysis was done using bioelectrical impedance analysis (BIA); weight, basal metabolic...

Background: Patients with cancer are at higher risk of contracting COVID-19 with poor prognosis. Therefore, the present study was conducted to investigate anxiety, spiritual well-being, and resilience levels in patients with cancer undergoing chemotherapy during the COVID-19 pandemic in the south of Fars Province, Iran. Methods: This is a descri...

Introduction:The most important change and evolution of adolescence, which is of special importance, is the process of puberty.Considering the sensitivity of adolescence and the characteristics of puberty, the present study was conducted to investigate the level of awareness and attitudes of male students, parents, and teachers regarding sexual pub...

Background & Objective: Prediction of preterm delivery can reduce a large number of its complications. The present study aimed to compare vaginal and plasma fibronectin concentrations in the diagnosis of preterm delivery.Materials & Methods: Serum samples were obtained from 105 women at 24-36 weeks of gestation. However, only 40 women gave permissi...

This randomized controlled clinical trial aimed to examine the effect of spirituality-based palliative care on pain, nausea, vomiting, and the quality of life in 80 Iranian colon cancer inpatients from January to June 2020 in southern Iran. Patients were randomly assigned to an intervention group and a control group. The intervention group took par...

Introduction: Hypertension is one of the most significant chronic diseases in all people, especially pregnant women, which can pose many risks to the mother and fetus. It also reduces the quality of life (QOL) of pregnant women. The aim of this study was to compare the effect of relaxation and cognitive counseling on blood pressure and quality of l...

Bisphenol A (BPA) is an endocrine disrupter with several adverse effects on human health and the natural ecosystem. BPA could be accumulated in marine environments and released into the food chain. The present study measured the concentration of BPA in 20 seawater samples, 128 fish as well as 20 urine samples of fishermen. Four highly used fish spe...

Why was the Fasa cohort set up? Non-communicable diseases (NCDs) are the leading cause of death in the world and accounted for 71% of all deaths in the world in 2016. The most important NCDs for this mortality are cardiovascular diseases (44% of all NCD deaths and 31% of all global deaths), cancers (22% of all NCD deaths and 16% of all global death...

Background: The present study aimed to compare the effect face-to-face and distance learning on knowledge, attitude and practice of females about breastfeeding in Shiraz, Iran. Methods: This randomized controlled trial was conducted in Shiraz, Iran in 2019 on 313 women who were referred to health centers (93 face-to-face group, 105 distance learnin...

Access the full text version of the article here: https://www.thelancet.com/journals/lanrhe/article/PIIS2665-9913(23)00098-X/fulltext

Objectives Opium use, cigarette smoking, and alcohol consumption are serious health problems in many countries including Iran. The present study aimed to examine the association between the opium use, cigarette smoking and alcohol consumption with liver enzyme levels in Southern Iran. This analytical cross-sectional study was conducted in 2020. The...

Background: Globorisk is a novel risk prediction model for predicting cardiovascular disease (CVD). Globorisk is a country-specific risk prediction model that determines CVD risk for all countries. This model has two versions; laboratory-based and office-based. This study aimed to determine the agreement between laboratory-based and office-based m...

Skin cancer is one of leading cancers globally, divided into two major categories including melanoma and nonmelanoma. Skin cancer is a global concern with an increasing trend, hence novel therapies are essential. The local treatment strategies play a key role in skin cancer therapy. Nanoparticles (NPs) exert potential applications in medicine with...

IntroductionSleeping is one of the most important human behaviors, which comprises one-third of human life. Sleeping process is required for proper performance of the brain. It is one of the important cycles of human life, which is repeated regularly and is directly associated with individuals’ activity while being awake. Human sleep is under the i...

Background: The musculoskeletal complaints of the shoulder are prevalent in people who work with computers for a long time. Objective: This study aimed to investigate the glenohumeral joint contact forces and kinematics in different keyboards and monitor setups using OpenSim. Material and Methods: Twelve randomly selected healthy males participated...

Cancers were the first cause of death in 2020; breast and skin are two common cancers worldwide. The most common cancer treatment approach is still chemotherapy; however, as side effects and multidrug resistance, the development of green nano drugs has received much attention. In this study, the chemical composition of Mentha spicata and Tanacetum...

Background: Understanding the magnitude of cancer burden attributable to potentially modifiable risk factors is crucial for development of effective prevention and mitigation strategies. We analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 to inform cancer control planning efforts globally. Methods:...