Azadeh Beizaei

University College Dublin | UCD · Systems Biology Ireland

Introduction: Cardiac troponin I (cTnI) is a highly specific biomarker of myocardial damage which can be used alone or in combination with other biomarkers for positive diagnosis of acute myocardial infarction. As 0.01 ng/ml concentration range has recommended for clinical cut off, developing precise and sensitive assays is highly desirable in poin...

Developing combination therapy for castrate-resistant prostate cancer (CRPC) may require exploiting new drug targets outside androgen receptor and PI3K / AKT / mTOR signal transduction pathways implicated in prostate cancer (PCa) progression. One such possible new target is YWHAZ of the 14-3-3 protein family as this gene has prognostic significance...

To provide an extended-release calcifediol supplement to dogs with CKD and to measure its effects on variables indicative of CKD-MBD. Animals: Ten dogs with International Renal Interest Society stages 2 and 3 CKD. Methods: In a prospective study, dogs received a calcifediol supplement for 84 days. Serum 25-hydroxyvitamin D (25[OH]D), 1,25-dihydroxy...

This is a highly sensitive assay to detect Aflatoxin in cereals by microarray immunoassay

We tested the hypothesis that patrolling myeloid cells due to their close association with the vascular lumen, play a role in regulating VSMC contraction.Presence of Myeloid cells significantly enhanced phenylephrine orangiotensin II-induced contraction by 25 to 80 folds. The intracellular calcium levels in VSMC at baseline was significantly enhanc...

There are over 34 millions people living with HIV worldwide and WHO guidelines recommend antiretroviral therapy (ART) treatment for HIV patients with a CD4+ T-cell count of less than 300 cells/ml. Clearly there is an urgent need for new technologies for HIV monitoring that produce accurate, rapid, and inexpensive viral load measurements. We have re...

There are over 34 millions people living with HIV worldwide and WHO guidelines recommend antiretroviral therapy (ART) treatment for HIV patients with a CD4+ T-cell count of less than 300 cells/ml. Clearly there is an urgent need for new technologies for HIV monitoring that produce accurate, rapid, and inexpensive viral load measurements. We have re...

We report a rapid, highly sensitive microarray method for quantitative aflatoxin B1 (AFB1) detection in cereal samples. Following optimisation using an indirect competitive immunoassay, optimised amounts of AFB1-bovine serum albumin (AFB1-BSA)-conjugate were contact-printed onto 16 isolated sub-arrays on multi-pad nitrocellulose coated slides subse...

Abstract Introduction: Unsaturated fatty acids are known to decrease serum leptin level. Considering that wild pistachio oil is a rich source of UFA and the reciprocal effects between leptin and thyroid hormones, the aim of the present study was to investigate the impact of dietary wild pistachio oil on serum leptin concentration and its relationsh...