Aysha Mezoughi

• PhD in Chemical Biology
• Assistant Professor at University of Tripoli

The micellar properties of the anionic surfactant, sodium dodecyl sulfate (SDS) are modified by the biologically active amino acids. Amino acids (AAs) have experienced a variety of interactions and are proposed to influence SDS micelles due to their nominated hydrophobic interactions. The present study determines the critical micellar concentration...

Silver nanoparticles (AgNPs) possess unusual optical, electrical, and catalytic properties. Hence, they are promising candidates in biomedical applications due to their shape and high surface area. Therefore, in present study, AgNPs were functionalized by using chalcone derivative as reducing and capping agent. The synthesized chalcone derivative w...

The study of the interaction between aspartic acid (Asp) and cetyltrimethylammonium bromide (CTAB) reveals important information about surfactant organization, surface tension, critical micelle concentration (CMC), and surface pressure. Because of enhanced surfactant solubility brought about by electrostatic interactions, Asp’s ionization lowers CT...

Silver nanoparticles (AgNPs) in this study are prepared in one-step using vitamin C (VC) and kojic acid (KA) as stabilized ligands in presence of sodium borohydride (NaBH4). As known, the Food and Drug Administration (FDA, USA) approved the use of KA for dermatological treatment purposes. Also, vitamin C as an antioxidant has reduced cancer disease...

Silver nanoparticles (AgNPs) have been boosted in the medical field because of using suitable stabilized ligands leading to create specific shapes and sizes. AgNPs in this study are prepared in one-step using vitamin C (VC) and kojic acid (KA) as stabilized ligands in presence of sodium borohydride (NaBH4). As known, the Food and Drug Administratio...

In this study, stable novel iron oxide nanoparticles (IO-NPs) were synthesized via chemical and green methods. In the chemical method, p-aminobenzoic acid (AB), diacetyl monoxime (DIA), and adenosine 5-monophosphate disodium (AD) were used as stabilized ligands, whereas the extract of Teucrium apollinis was used in the green synthesis method. The e...

In this study, stable novel iron oxide nanoparticles (IO-NPs) were synthesized via chemical and green methods. In the chemical method, p-aminobenzoic acid (AB), diacetyl monoxime (DIA), and adenosine 5-monophosphate disodium (AD) were used as stabilized ligands, whereas the extract of Teucrium apollinis was used in the green synthesis method. The e...

Silver nanoparticles (AgNPs) in this study are prepared in one step using vitamin C (VC) and kojic acid (KA) as stabilized ligands in the presence of sodium borohydride (NaBH4). As known, the Food and Drug Administration (FDA, USA) approved the use of KA for dermatological treatment purposes. Also, vitamin C as an antioxidant has reduced cancer dis...

The micellar properties of the anionic surfactant, sodium dodecyl sulfate (SDS) are modified by the biologically active amino acids. Amino acids (AAs) have experienced a variety of interactions and are proposed to influence SDS micelles due to their nominated hydrophobic interactions. The present study determines the critical micellar concentration...

Gold nanoparticles (AuNPs) have received considerable attention recently because of their chemical properties and potential applications in the medical field.Monodispersed AuNPs in this paper are successfully synthesized by using some stabilized ligands including 3,5-dinitrobenzoic acid (DNBA) and sodium acetate (SA) dispersible in aqueous media, w...

2-Thiohydantoin derivatives are most remarkably known because of their extensive applications including, hypolipidemic, anticarcinogenic, antimutagenic, antifungal and antibacterial. For this reason, three of 5-aryl-2-thiohydantion derivatives (3-5) and the conversion of 2-thiohydantoin to thiol ether (7) by alkylation with methyl bromoacetate are...

Background: In Covid-19 the virus infects the respiratory tract in humans. When lung tissue becomes diseased, the walls and lining of the alveoli and capillaries are damaged. At this point lung compliance and ventilation decrease. A pulmonary surfactant that is produced and dispersed into alveolar space, has a significant role in understanding how...

Lytic transglycosylases such as Slt35 from E. coli are enzymes involved in bacterial cell wall remodelling and recycling, which represent potential targets for novel antibacterial agents. Here, we investigated a series of known glycosidase inhibitors for their ability to inhibit Slt35. While glycosidase inhibitors such as 1-deoxynojirimycin, castan...

Alkyl 3-aminothiophene carboxylates derivatives (3a-d) were prepared via reaction of (4-oxo-3-phenyl-1,3-thiazolidin-2-ylidene)malononitrile (2) with alcohols. Compound 3a was allowed to react with acetic anhydride, chloroacetyl chloride and nitrous acid to afford N,N,N-triacetylthiophene, 3-chloro-acetamidothiophene and 3-diazothiophene derivative...

2-Ylidene and 2,5-diylidene-4-thiazolidinones 2a–d were synthesized and converted into pyrazole derivatives 4a–d by reaction with hydrazine hydrate. A mechanism of this novel conversion is suggested.

Ketene N,S-acetal potassium salts (2a–g), prepared via reaction of active methylenes (1a–g) with phenyl isothiocyanate in the presence of potassium hydroxide, were allowed to react with ethyl chloroacetate or chloroacetamide to afford the corresponding 2-ylidene-4-thiazolidinones (3a–g) in good yields. Compounds (3a–g) reacted with a variety of aro...