Aysegul Oruc

Aysegul Oruc
Uludag University · Division of Nephrology

Assoc. Prof. Dr.

About

151
Publications
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230
Citations

Publications

Publications (151)
Article
Background: We aimed to evaluate the perceptions of nephrologists about PD in Turkey. Material-method: An anonymous survey was conducted to a total of 150 nephrologists. Demographic data, perceptions, PD indications, contraindications, and possible reasons for low preference of PD were questioned. Results: In decision-making 93.4% of all state...
Article
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BACKGROUND AND AIMS There is not enough data on the post-COVID-19 (coronavirus disease 2019) period for peritoneal dialysis (PD) patients affected from COVID-19. We aimed to compare the clinical and laboratory data retrospectively obtained in the follow-up of PD patients after COVID-19 with a control PD group. METHOD This study, supported by the T...
Article
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BACKGROUND AND AIMS Although existing data suggest an increased mortality rate, data about the course of coronavirus disease 2019 (COVID-19) in peritoneal dialysis (PD) patients, its short- and long-term effects on the patient and technique survival are limited. Moreover, specific factors associated with increased risk of death have not been clearl...
Conference Paper
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Although it has been reported rarely in the literature in patients who develop acute kidney injury after COVID-19 disease, ANCA-related vasculitis should also be kept in mind. Thus, it is possible to reduce mortality and morbidity. We presented a middle-aged male patient who was diagnosed with post-COVID ANCA-associated vasculitis
Article
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INTRODUCTION: The activation of the sympathetic nervous system, which usually leads to a swift surge in blood pressure in the morning hours (MBPS) may be the cause of left ventricular hypertrophy (LVH) and endothelial dysfunction (ED) in early autosomal dominant polycystic kidney disease (ADPKD) patients. We studied the association between MBPS and...
Article
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Background In autosomal dominant polycystic kidney disease (ADPKD), endothelial dysfunction (ED) is common and occurs much earlier than kidney function impairment. The impact of smoking on ED in ADPKD patients has not been previously studied. The aim of this study was to investigate the potential contribution of smoking habits to ED and subclinical...
Article
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Background: The X-linked Fabry disease (FD) with lysosomal storage of globotriaosylceramide (Gb3) due to α-galactosidase deficiency contributes to nephropathy consisting of proteinuria and renal failure eventually. Early initiation of the enzyme replacement therapy promises favorable renal outcomes. With the importance of early diagnosis, we screen...
Article
Full-text available
Background: The X-linked Fabry disease (FD) with lysosomal storage of globotriaosylceramide (Gb3) due to α-galactosidase deficiency contributes to nephropathy consisting of proteinuria and renal failure eventually. Early initiation of the enzyme replacement therapy promises favorable renal outcomes. With the importance of early diagnosis, we screen...
Article
Background The novel coronavirus disease was declared as a pandemic and chronic kidney disease is an important risk factor for morbidity and mortality. Dialysis has additional contributions on transmission risk so prompt preventive strategies were implemented for dialysis patients. We aimed to evaluate pandemic-related perceptions and concerns of d...
Article
Background The novel coronavirus disease was declared as a pandemic and chronic kidney disease is an important risk factor for morbidity and mortality. Dialysis has additional contributions on transmission risk so prompt preventive strategies were implemented for dialysis patients. We aimed to evaluate pandemic-related perceptions and concerns of d...
Article
Full-text available
We describe a patient with membranous nephropathy (MN) who stayed in remission for 8 years and experienced a relapse after vaccination with a purified inactivated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus vaccine called CoronaVac (produced in China by Sinovac).
Article
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Purpose Hematuria is one of the most common laboratory findings in nephrology practice. To date, there is no enough data regarding the clinical and histopathologic characteristics of primary glomerular disease (PGD) patients with hematuria in our country. Methods Data were obtained from national multicenter (47 centers) data entered into the Turki...
Conference Paper
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Sjogren's syndrome (SjS) is a chronic, slow-progressing, autoimmune and lymphoproliferative disease. The main symptoms of the syndrome are xerostomia and keratoconjuctivitis sicca as a result of chronic inflammatory infiltration of the salivary and lacrimal glands. Focal Segmental Glomerulosclerosis complicating primary Sjögren's syndrome is extrem...
Conference Paper
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Autoimmune hemolytic anemia (AIHA) is a rare disease with a rate of 1-3 in 100,000 in adults. AIHA are defined as primary (idiopathic) or secondary depending on the presence or absence of accompanying disease. Secondary causes include drugs, immunodeficiencies, infections, other autoimmune diseases, or malignancies. Here, we report an 42-year-old f...
Conference Paper
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Light chain myeloma nephropathy is the most common form of renal involvement in plasma cell dyscrasias. It usually causes tubulointerstitial renal damage. About one in five people with multiple myeloma produce only light chains. We report a case of lambda light chain deposition disease in a 61-year-old female who presented with acute renal failure....
Article
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Evaluation of Death Patients on the Cadaveric Kidney Waiting List of Bursa Uludağ University Medical Faculty According to Years by Gender, Age, Blood Type, Dialysis Type In Turkey, there is 22953 end-stage kidney disease patient in national deceased kidney waiting list (1). According to the 2019 Registry Report of the Turkish Society of Nephrology,...
Article
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In Turkey, there is 22953 end-stage kidney disease patient in national deceased kidney waiting list (1). According to the 2019 Registry Report of the Turkish Society of Nephrology, the number of patients receiving hemodialysis (HD) and peritoneal dialysis (PD) treatment is 64633 (2). However, patients registered on the national kidney waiting list...
Article
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Background. Chronic kidney disease (CKD) and immunosuppression, such as in renal transplantation (RT), stand as one of the established potential risk factors for severe coronavirus disease 2019 (COVID-19). Case morbidity and mortality rates for any type of infection have always been much higher in CKD, haemodialysis (HD) and RT patients than in the...
Article
Spondin 2 (SPON2) plays an important role in multiple processes and is a member of the Spondin 2/F-spondin family of extracellular matrix proteins. We investigated serum SPON2 levels and its correlation with renal functions and urine protein excretion in different glomerular diseases. The cohort included 97 consecutive adults with persistant protei...
Article
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Background: Hypervolemia is an important consequence of heart failure (HF) that leads to poor quality of life and frequent hospitalizations. Ultrafiltration (UF) with dialysis is an option for HF patients who are resistant or inappropriate for diuretics. Peritoneal dialysis (PD) can be a long-term efficient solution for hypervolemia in appropriate...
Preprint
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Background Interferon and/or ribavirin treatment previously used in the treatment of HCV cannot be used effectively in hemodialysis patients due to dose adjustment and drug-related side effects. The direct-acting antiviral combination (DAA) is reported to be effective in hemodialysis patients. We evaluated the effectiveness of DAA in hemodialysis p...
Poster
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Objective: End-stage kidney disease is gradually increasing all over the world. In these patients, hemodialysis, peritoneal dialysis, or kidney transplant methods are used as replacement therapy. Kidney transplantation is the best treatment option because it improves the quality of life and reduces cost. In this study, the 1-year, 5-year and 10-yea...
Article
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Background: Persistent hypercalcemia and hyperparathyroidism after successful kidney transplantation can be detrimental in some recipients and should be ameliorated. Objective: To point out the concerns regarding resistance to cinacalcet in kidney transplant recipients with persistent hypercalcemia. Methods: 14 renal transplant recipients who...
Article
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Bupropion is a drug used to smoke cessation. Various complications have been reported after using this drug. In a 58-year-old female patient, skin findings and anti-Ro52 positivity developed after the use of this drug. Later, signs of vasculitis appeared under immunosuppressive therapy. The patient was diagnosed with cutaneous and systemic lupus er...
Article
Background and Aims Hematuria is one of the most common laboratory findings in nephrology practice. In different regions of the world, the etiologic causes differ. To date, there is no enough data regarding the clinical and histopathologic characteristics of primary glomerular diseases (PGD) patients with hematuria in our country. Method Data were...
Article
Full-text available
Background and Aims Membranous nephropathy (MN) is the most common cause of nephrotic syndrome in the adult population. The aim of our study is to determine the demographic and clinical characteristics and biopsy findings of the patients diagnosed with MN in our country. Method The study included 991 patients with renal biopsy who were followed in...
Article
Fabry disease, also known as Anderson-Fabry disease, is a X-linked lysosomal storage disease. Alpha-galactosidase A (alpha-Gal A) enzyme deficiency leads globotriaosylceramide (Gb3) accumulation in several cells which causes clinical manifestations of the disease. The clinical heterogeneity and non-specific symptoms cause under-diagnosis and diagno...
Article
Sistemik vaskülitler, inflamatuvar değişiklikler ile damar duvarı hasarına neden olan ve nekroz, tromboz, anevrizma oluşumu ve buna bağlı doku hasarı ile karakterize bir grup hastalıktır. İdiyopatik (primer) veya enfeksiyonlar, romatolojik hastalıklar, maligniteler ve ilaçlar gibi çeşitli etiyolojilere sekonder olabilir. Vaskülite bağlı klinik beli...
Article
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Objectives: Persistent hyperparathyroidism can have a deleterious effect on graft function in kidney transplant recipients, although serum calcium, phosphorus, and parathyroid hormone levels tend to normalize after successful transplant. Parathyroidectomy can result in sustained amelioration of persistent hyperparathyroidism despite graft failure...
Conference Paper
Full-text available
Kidney transplantation provides better survival and quality of life for patients with end-stage kidney disease. Success of transplantation depends on various factors such as immunosuppressive treatment adherence (ISTA). Non-adherence to immunosuppressive treatment is a prognostic indicator for poor long-term post-transplantation outcomes. ISTA is u...
Article
Full-text available
OBJECTIVE: Our aim was to assess cognitive dysfunction, which is common in hemodialysis patients and difficult to diagnose, by an easily applicable test, the Mini Mental State Examination and Clock Drawing Test. MATERIAL and METHODS: Two hundred and sixty six (266, 88.37%) dialysis patients that were followed-up at the Nephrology Clinic of Bursa Sp...
Article
Objective Besides severe organ shortage hepatitis C virus (HCV) infection is an important obstacle for kidney transplantation because of long waiting times on deceased kidney donor waiting lists. We aimed to evaluate calling number of candidates according to HCV serology. Method A total 404 adults in deceased donor waiting list invited for cadaver...
Article
Objective: Encapsulating peritoneal sclerosis (EPS) is a serious complication for patients with chronic kidney disease (CKD) who were treated with long-term peritoneal dialysis (PD). The risk of EPS was increased after kidney transplantation. In our study we evaluated risk factors for EPS patients after kidney transplantation who were treated befo...
Article
Full-text available
INTRODUCTION: Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common hereditary kidney disease and nephrolithiasis is frequent among ADPKD patients compared with general population. In this study, we aimed to review the factors associated with the development of kidney stones in ADPKD patients. METHODS: A total of 118 ADPKD patient...
Article
Full-text available
OBJECTIVE: Oxidative stress (OS) is described as the imbalance of oxidative and anti-oxidative systems towards oxidants and plays a role in the pathogenesis of GN. In many studies, ischemia-modified albumin (IMA) is identified as a sign of OS. However, it has not yet been studied in patients with primary GN in the literature. In the present study,...