Aylin Akbulut

Aylin Akbulut
University of Health Sciences Ankara Training and Application Hospital · Nuclear medicine

M.D.

About

55
Publications
6,188
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195
Citations
Citations since 2016
34 Research Items
133 Citations
201620172018201920202021202205101520
201620172018201920202021202205101520
201620172018201920202021202205101520
201620172018201920202021202205101520

Publications

Publications (55)
Article
Purpose: To evaluate the radioprotective effect of spirulina (SP) on the lacrimal glands after RAI treatment. Methods: A total of 30 rats were separated into control, RAI and SP group. The radioprotective effect of SP on lacrimal glands was evaluated with histopathological and cytopathological analysis. Lacrimal glands were analyzed for tumor ne...
Article
Objective: The present study was aimed to explore the potential ameliorating effects of N-acetyl cysteine (NAC) against radioiodine (RAI)-induced early liver damage. Methods: Thirty Wistar Albino male rats were arbitrarily allocated into three groups each containing 10 rats: the control group (group 1); the RAI group (group 2), oral 111 MBq/kg rad...
Article
The aim of this study was to investigated anti-proliferative and anti-apoptotic effects of coenzyme Q10 (CoQ10) in the prevention of radioiodine-131 (RAI) (I131) induced kidney damage. A total of 24 Wistar albino rats were seperated into equal three groups (n = 8/group): Group 1 (control): untreated group; Group 2 (RAI): 3 mCi/kg RAI oral route; Gr...
Article
Full-text available
Purpose: To evaluate protective effects of dexmedetomidine, calcitriol and their combination. Methods: Forty Wistar-albino rats were divided into 4 groups; group of Sham (Group Sham); group of dexmedetomidine (Group DEX); group of calcitriol (Group CAL) and group of dexmedetomidineandcalcitriol (Group DEX-CAL). Photographic analysis was used for m...
Article
Purpose We have evaluated the potential radioprotective, antioxidant and anti-apoptotic effects of resveratrol (RSV) against high-dose radioactive iodine (RAI) therapy associated damage of the lacrimal glands by biochemical, histopathological and immunohistochemical methods. Materials and Methods Thirty Wistar-albino rats were randomly divided int...
Article
Aim: The uses of plant based hemostatic agents are increasing for obtaining operative field hemostasis. However, their effects on vascularly challenged tissue is not known. The aim of this study was to investigate the effect, if any, of plant- based hemostatic agent, Ankaferd (ABS) on flap viability in a rat model. Material and Methods: Twenty rat...
Article
Full-text available
Objectives: The aim of this study was to show the efficacy of coenzyme Q10, known as anti-oxidant with anti-inflammatory properties, in liver damage after renal ischemia-reperfusion (RIR). Materials and Methods: For this purpose, rats were divided into three groups to design an experimental RIR model. Group 1 rats were Sham group. Group 2 rats unde...
Article
Purpose: Renal ischemia-reperfusion injury (RIRI) may occur secondary to several reasons leading to renal failure. Coenzyme-Q10 (CoQ10) is a well-known antioxidant. However, the effects CoQ10 against RIRI have not been evaluated. Our aim was to evaluate protective effects of CoQ10 to renal ischemia-reperfusion by biochemical, immunohistochemical a...
Article
Aim: Our goal was to evaluate the gastric emptying time in either reflux positive and negative children; and also the first reflux time, the number of reflux episodes in scintigraphy, reflux index (RI), and gastric emptying half time for liquids in infants and in children who were referred to our department for gastroesophageal reflux scintigraphy...
Article
Ectopic lingual thyroid is a rare developmental abnormality caused by aberrant embryogenesis during thyroid migration. Even though, most patients are asymptomatic, uncommonly the mass can be enlarged and cause dysphagia, dyspnea, upper airway obstruction, dysphonia, hypothyroidism. We report a very rare case of ectopic lingual thyroid presenting wi...
Article
Background Supernumerary kidney is an accessory organ with its own encapsulated parenchyma, blood vessels and ureters, either separated from the normal kidney or connected to it via fibrous tissue and ectopic kidney is a migration abnormality of the kidney. Here, we have evaluated a rare case of the supernumerary and ectopic kidney with DMSA, MAG3...
Article
Development of the apical pouches is a rare finding in HCM. Possible causes explaining the mechanism are the increased afterload and high apical pressure, ventricular remodeling, the increased oxygen need due to increased myocardial thickness and decreased oxygen reserve due to the decreased capillary network and apical myocardial infarction. The r...
Article
Objectives: The aim of the present study was to investigate the radioprotective effect of vitamin E in the prevention of radioiodine (RAI) induced gastrointestinal damage. Method: Twenty-four rats were randomly divided into three groups as follows: Group-1 was untreated control group, Group-2 was orally administered single dose of 111 MBq RAI, a...
Technical Report
Full-text available
The early repolarization pattern and gated SPECT abnormality at coronary stenosis.
Article
Primary diffuse leptomeningeal melanomatosis is a rare variant of malignant melanoma of the central nervous system, arising from melanocytes of leptomeninges. It may involve leptomeninges and may invade brain superficially. The diagnosis of the disease with conventional imaging techniques is quite difficult. This case demonstrates the F-FDG uptake...
Article
Multifocal nodular oncocytic hyperplasia (MNOH) is a rare lesion of the parotid gland and bilateral cases are extremely rare. We report the case of a 69-year-old woman who was operated from MNOH 10 years ago and the bilateralism of the case appeared 10 years later making the case metachronous.
Article
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Maxillary Sinusitis Mimicking Bone Metastasis in a Patient with MEN 2A
Article
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Background: Radioiodine I131 therapy (RAI) is an efficient method to decrease the function of very active thyroid tissues and to ablate the remnant thyroidal tissue after surgery and its metastases in differentiated thyroid carcinomas. Several cytoprotective, anti-oxidant or radioprotective mediators have been used in trials regarding RAI induced d...
Article
Full-text available
Purpose: Radioactive I131 (RAI) therapy is a standard method to ablate the remnant thyroidal tissue after total thyroidectomy and its metastases in differentiated thyroid carcinomas, however, I131 also accumulates in non-thyroidal tissue, which may cause adverse effects and limit the I131 dose required for treatment. We hypothesized that montelukas...
Article
Full-text available
The thyroid gland may show anatomical variations related to embryonic developmental stages. Persistence of the thyroglossal duct is the cause of most variations in the thyroid gland, which are seen as cyst or ectopic thyroid tissue formation and the pyramidal lobe. The presented case is a patient with Graves’ disease showing two pyramidal lobes at...
Article
Purpose: The aim of this study was to evaluate the effect of lycopene against radioactive iodine (RAI)-related gastrointestinal tract acute damage in a rat model as a novel radioprotective agent. Materials and methods: Twenty Wistar albino rats were divided into two equal groups: group 1 was administered only RAI and group 2 was administered RAI...
Article
Full-text available
A 63-year-old woman presented with a history of hyperthyroidism symptoms over two years, referred for thyroid scintigraphy. In the hospital archives we have met her previous thyroid scintigraphy showing a hot nodule in the upper part of right thyroid lobe. However, her recent thyroid scintigraphy was showing only cold nodules but no hot nodule, giv...
Article
Full-text available
Background: Endometriosis is defined as the implantation of endometrial gland and stroma ectopically outside the uterus. Clinically, it is a hormone dependent benign disease accompanied by pelvic pain and infertility. The aim of this study was to demonstrate the activated implants with 99m-Tc labeled erythrocyte scintigraphy (99mTc-RBCs) in patient...
Article
Full-text available
Background: We evaluated the stump region with scintigraphy and compared the correlation of treatment modalities and scintigraphic results. Methods: Sixty-eight cases with extremity amputation were included in the study. Amputation applied cases underwent four-phase Tc-99m hydroxymethylene diphosphonate scintigraphy. Groups were performed accord...
Article
Full-text available
To assess the frequency and the significance of incidental pulmonary lesions with 18F-fluorocholine (18F-FCH) PET/CT in prostate cancer (PCa) patients. 225 consecutive PCa patients referred for 18F-FCH PET/CT (median age 68 years) were retrospectively evaluated for the presence of lesions in the lungs: 173 referred for restaging and 52 for initial...
Article
Full-text available
Objective: To investigate the prevalence of Helicobacter pylori (Hp) infection in pre-school and school age children with C-14 urea breath test, and to explore its association with age and socioeconomic factors in Turkey. Methods: Hp infection status was determined by using Urea Breath Test (UBT). Patients who had previous gastric surgery, Hp eradi...
Article
Full-text available
Primary intrathoracic thyroid is a rare entity, lacking direct connection to the orthotopic gland. However it is even rarer to identify these tissues in asymptomatic patients. Here, we report a patient of incidental primary intrathoracic thyroid tissue in thyroid scintigraphy. A 58-year-old female patient was referred for the evaluation of her thyr...
Article
Full-text available
In this case report, we present a 70 year old female patient who had recieved Leech therapy (hirudotherapy) on her leg without informing referring physician. In dynamic bone scintigraphy there was increased perfusion and hyperemia in her left ankle and leg, also in late static images moderate increased uptake was seen in soft tissue region and at t...
Article
Full-text available
Molecular imaging with various biomarkers plays a significant role in the diagnostic assessment of patients with dementing disorders, by detecting functional and pathophysiologic changes in the brain. PET imaging, in particular, allows the measurements of different molecular targets, such as functional markers of neurodegeneration (glucose metaboli...
Article
Full-text available
Hypoxia, a condition of insufficient oxygen availability to support metabolism, occurs when the vascular supply is interrupted, as in stroke. The identification of the hypoxic and viable tissue in stroke as compared with irreversible lesions (necrosis) has relevant implications for the treatment of ischemic stroke. Traditionally, imaging by positro...
Article
Full-text available
We present the case of a 21-year-old man who was referred to us for parathyroid scintigraphy with high blood levels of intact parathormone and osteoporosis. Several methods and radiopharmaceuticals, e.g., Tc-99m MIBI and Tl-201 chloride/Tc-99m pertechnetate (Tl-201/TcPO−4) subtraction, are commonly used for this purpose. We present the case of a th...
Article
Full-text available
Multimodality image registration plays a crucial role in various clinical and research applications. The aim of this study is to present an optimized MR to CT whole‐body deformable image registration algorithm and its validation using clinical studies. A 3D intermodality registration technique based on B‐spline transformation was performed using op...
Article
Full-text available
Background: Diffuse pigmented villonodular synovitis (DPVNS) is an uncommon proliferative disease. After only surgery, recurrence rates are high. This study presents the efficacy of combined surgical and adjuvant radiosynovectomy (RS) in the treatment of DPVNS. Materials and methods: Between September 2006 and September 2012, 15 knee joints of 1...
Chapter
In both Hodgkin disease and non-Hodgkin lymphoma, imaging plays an important role for primary diagnosis and staging [1]. Except for cerebral lymphoma, whole-body MRI is of high research interest but not clinical routine in the staging algorithm of lymphoma patients. This situation could change quickly, and whole-body MRI might become a good alterna...
Chapter
Breast cancer is the leading cancer and the second leading cause of mortality in women in most European countries, North America, and Australia. In Europe, 1 out of every 10–15 women will develop breast cancer in her lifetime, and the risk is even higher in the United States, where it is 1 out of every 8 women. PET-CT was shown to be useful for det...
Chapter
FDG-PET is already recommended to evaluate lymph node extension and was proven superior to MRI for detection of lombo-aortic lymph node extension, which is a major prognostic factor. Given its excellent soft-tissue contrast, MRI plays an important role at diagnosis in the delineation of cervical lesions, and possible vaginal, parametrial, rectal or...
Chapter
Because of its high soft-tissue contrast, MRI is the method of choice for the assessment of brain tumors. Conventional MRI sequences provide excellent visualization of the lesions, but still have limitations for the accurate definition of lesion boundaries and for differentiating some treatment related changes and tumor recurrence. MRI techniques s...
Chapter
Prostate cancer is biologically and clinically a heterogeneous disease that makes imaging evaluation challenging because different stages of prostate cancer are managed with different treatment modalities. The role of imaging in prostate cancer includes diagnosis, localization and characterization of the primary tumor, determination of extracapsula...
Article
Full-text available
The use of coronary calcium scoring (CaScCT) for attenuation correction (AC) of (13)N-ammonia PET/CT studies (NH3) is still being debated. We compare standard ACCT to CaScCT using various respiratory phases and co-registration methods for AC. Forty-one patients underwent a stress/rest NH3. Standard ACCT scans and CaScCT acquired during inspiration...
Article
Full-text available
Multimodality image registration plays a crucial role in various clinical and research applications. The aim of this study is to present an optimized MR to CT whole-body deformable image registration algorithm and its validation using clinical studies. A 3D intermodality registration technique based on B-spline transformation was performed using op...
Article
Pulmonary embolism (PE) is a major health problem associated with a significant morbidity and mortality. Immediate recognition of submassive and massive cases is extremely important in order to commencement of early and appropriate therapy that could be life saving. The aim of this study was to assess the ability of two scoring systems, electrocard...

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Projects (2)
Project
salivary gland, lacrimal gland