Ayfer Ali

Warwick Business School · Department of Strategy and International Business

Exaptation, the emergence of latent functionality in existing artifacts, is an underexplored mechanism of novelty generation in innovation. In this paper, we measure the frequency of exaptation in the pharmaceutical industry. We find that about 42% of new functions derived from existing drugs have an exaptive nature. We think that this constitutes...

In recent decades, teams that combine basic scientists with clinical researchers have become an important organizational mechanism to translate knowledge made in basic science ("the bench") to tangible medical innovations ("the bedside"). Our study explores whether inventing teams that span basic and clinical research are more effective at licensin...

Exaptation, the preadaptation of technologies for unintended functions, is an important mechanism in the expansion of the technosphere. In this paper we propose a method to measure the frequency of exaptation. We apply it to the pharmaceutical sector and offer the first measure of the frequency of exaption in an industry. We show that exaptation ac...

Research on markets for technology has suggested that lack of participation in these markets generally stems from the need of complementary technologies in the licensing firm. Lack of participation may also be due to a lack of complementarity that unfolds over the time dimension. In fact, the value of a technological innovation to a firm may depend...

Objective: To determine the role of clinicians in the discovery of off-label use of prescription drugs approved by the United States Food and Drug Administration (FDA). Data Sources. Micromedex Healthcare Series was used to identify new uses of new molecular entities approved by the FDA in 1998, literature from January 1999-December 2003 was acces...

Objectives. This article examines all postwar Summer and Winter Olympic Games in order to investigate the economic and political determinants of participation and medal-winning success. Methods. Using newly compiled data, regression analysis gives intuitive results with surprisingly accurate predictions beyond the historical sample. We also estimat...

Objectives. This article examines all postwar Summer and Winter Olympic Games in order to investigate the economic and political determinants of participation and medal-winning success. Methods. Using newly compiled data, regression analysis gives intuitive results with surprisingly accurate predictions beyond the historical sample. We also estimat...

This paper investigates the post-War Summer Olympic Games in order to determine the economic and political determinants of national participation, and of female participation in particular. Success at the Games (i.e., medal counts) is then analyzed in two ways, from the individual level and the national level, showing similar results. Female partic...

The great leaps that have been made in basic life sciences in recent decades have brought to light the need for translating these findings into practical applications.1 The increased amount of funding that goes into translational research emphasizes the need for interdisciplinary and multidisciplinary team collaboration as well as training of inter...